Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CT47B1 Gene

Aliases for CT47B1 Gene

  • Cancer/Testis Antigen Family 47, Member B1 2 3 5
  • Cancer/Testis CT47 Family, Member 13 2 3
  • Cancer/Testis Antigen 47.13 3 4
  • CT47.13 3 4
  • Cancer/Testis Antigen Family 147, Member B1 3
  • Cancer/Testis Antigen 47B 3
  • CT47A13 3

External Ids for CT47B1 Gene

Previous GeneCards Identifiers for CT47B1 Gene

  • GC0XM119893
  • GC0XM120006

Summaries for CT47B1 Gene

GeneCards Summary for CT47B1 Gene

CT47B1 (Cancer/Testis Antigen Family 47, Member B1) is a Protein Coding gene. An important paralog of this gene is CT47A8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CT47B1 Gene

Genomics for CT47B1 Gene

Regulatory Elements for CT47B1 Gene

Enhancers for CT47B1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF120313 1.1 ENCODE 16.2 +566.2 566229 0.3 PKNOX1 ARID4B FEZF1 ZNF2 ZNF302 ZNF416 ZNF143 ZNF548 SP3 REST NKAPP1 EEF1A1P30 RHOXF2B CT47B1 CT47A1 CT47A6 CT47A12 ZBTB33 NKAP CXorf56
GH0XF120309 1 ENCODE 16.2 +566.5 566516 0.2 PKNOX1 ZNF133 ARID4B FEZF1 GLI4 ZNF48 ZNF2 ZNF121 GLIS2 ZNF416 NKAPP1 EEF1A1P30 RHOXF2B CT47B1 CT47A1 CT47A6 CT47A12 ZBTB33 NKAP CXorf56
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CT47B1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CT47B1 Gene

Chromosome:
X
Start:
120,872,597 bp from pter
End:
120,875,929 bp from pter
Size:
3,333 bases
Orientation:
Minus strand

Genomic View for CT47B1 Gene

Genes around CT47B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CT47B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CT47B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CT47B1 Gene

Proteins for CT47B1 Gene

  • Protein details for CT47B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C2W7-CT47B_HUMAN
    Recommended name:
    Cancer/testis antigen 47B
    Protein Accession:
    P0C2W7
    Secondary Accessions:
    • A6NM97

    Protein attributes for CT47B1 Gene

    Size:
    299 amino acids
    Molecular mass:
    31319 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CT47B1 Gene

Post-translational modifications for CT47B1 Gene

No Post-translational modifications

Other Protein References for CT47B1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CT47B1 Gene

Domains & Families for CT47B1 Gene

Protein Domains for CT47B1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CT47B1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CT47B1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CT47B1 Gene

Function for CT47B1 Gene

Phenotypes for CT47B1 Gene

GenomeRNAi human phenotypes for CT47B1:
genes like me logo Genes that share phenotypes with CT47B1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CT47B1 Gene

Localization for CT47B1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CT47B1 gene
Compartment Confidence
nucleus 2
cytosol 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CT47B1 Gene

Pathways & Interactions for CT47B1 Gene

SuperPathways for CT47B1 Gene

No Data Available

Interacting Proteins for CT47B1 Gene

Gene Ontology (GO) - Biological Process for CT47B1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CT47B1 Gene

Transcripts for CT47B1 Gene

mRNA/cDNA for CT47B1 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CT47B1 Gene

Cancer/testis antigen family 47, member B1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CT47B1 Gene

No ASD Table

Relevant External Links for CT47B1 Gene

GeneLoc Exon Structure for
CT47B1
ECgene alternative splicing isoforms for
CT47B1

Expression for CT47B1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CT47B1 Gene

mRNA differential expression in normal tissues according to GTEx for CT47B1 Gene

This gene is overexpressed in Testis (x52.6).

Protein differential expression in normal tissues from HIPED for CT47B1 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CT47B1 Gene



Protein tissue co-expression partners for CT47B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of CT47B1 Gene:

CT47B1

SOURCE GeneReport for Unigene cluster for CT47B1 Gene:

Hs.729566
genes like me logo Genes that share expression patterns with CT47B1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CT47B1 Gene

Orthologs for CT47B1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CT47B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CT47B1 34 35
  • 97.55 (n)
dog
(Canis familiaris)
Mammalia -- 35
  • 22 (a)
OneToMany
Species where no ortholog for CT47B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CT47B1 Gene

ENSEMBL:
Gene Tree for CT47B1 (if available)
TreeFam:
Gene Tree for CT47B1 (if available)

Paralogs for CT47B1 Gene

(12) SIMAP similar genes for CT47B1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CT47B1: view

Variants for CT47B1 Gene

Sequence variations from dbSNP and Humsavar for CT47B1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111967197 -- 120,873,655(+) GCCAA(A/G)AAGTA intron-variant
rs112723019 -- 120,873,275(+) TAAGA(A/C)TTCAT intron-variant
rs116730381 -- 120,874,768(+) ACCTG(C/T)TTCAC intron-variant
rs139114591 -- 120,875,089(+) ACCGA(C/T)GCAGC reference, synonymous-codon
rs140225257 -- 120,872,843(+) CACCA(C/G)TGACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CT47B1 Gene

Variant ID Type Subtype PubMed ID
esv27639 CNV gain+loss 19812545
nsv515167 CNV gain 21397061
nsv7061 CNV deletion 18451855
nsv820952 CNV deletion 20802225
nsv9972 CNV gain+loss 18304495

Variation tolerance for CT47B1 Gene

Residual Variation Intolerance Score: 98.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.57; 30.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CT47B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CT47B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CT47B1 Gene

Disorders for CT47B1 Gene

Relevant External Links for CT47B1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CT47B1

No disorders were found for CT47B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CT47B1 Gene

Publications for CT47B1 Gene

  1. Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome. (PMID: 16382448) Chen Y.-T. … Jongeneel C.V. (Genes Chromosomes Cancer 2006) 2 3 4 64
  2. Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE. (PMID: 23092983) Nava C. … Depienne C. (Transl Psychiatry 2012) 4 64
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 64

Products for CT47B1 Gene

Sources for CT47B1 Gene

Content
Loading form....