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Aliases for CT45A3 Gene

Aliases for CT45A3 Gene

  • Cancer/Testis Antigen Family 45, Member A3 2 3
  • Cancer/Testis Antigen CT45-3 2 3
  • Cancer/Testis Antigen 45-3 3 4
  • Cancer/Testis Antigen 45A3 3 4
  • CT45.3 3 6
  • CT45-3 3 4
  • Cancer/Testis Antigen Family 45 Member A3 3

External Ids for CT45A3 Gene

Previous GeneCards Identifiers for CT45A3 Gene

  • GC0XP134712
  • GC0XP134869

Summaries for CT45A3 Gene

GeneCards Summary for CT45A3 Gene

CT45A3 (Cancer/Testis Antigen Family 45, Member A3) is a Protein Coding gene. An important paralog of this gene is LOC101060211.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CT45A3 Gene

Genomics for CT45A3 Gene

Regulatory Elements for CT45A3 Gene

Genomic Location for CT45A3 Gene

Start:
135,759,846 bp from pter
End:
135,777,474 bp from pter
Size:
17,629 bases
Orientation:
Minus strand

Genomic View for CT45A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CT45A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CT45A3 Gene

Proteins for CT45A3 Gene

  • Protein details for CT45A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHU0-CT453_HUMAN
    Recommended name:
    Cancer/testis antigen family 45 member A3
    Protein Accession:
    Q8NHU0
    Secondary Accessions:
    • B2RU20
    • B7ZMC9
    • D3DTG6

    Protein attributes for CT45A3 Gene

    Size:
    189 amino acids
    Molecular mass:
    21331 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CT45A3 Gene

Proteomics data for CT45A3 Gene at MOPED

Post-translational modifications for CT45A3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CT45A3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CT45A3 Gene

Domains for CT45A3 Gene

Protein Domains for CT45A3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CT45A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CT45A3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CT45A3 Gene

Function for CT45A3 Gene

Gene Ontology (GO) - Molecular Function for CT45A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with CT45A3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CT45A3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CT45A3 Gene

Localization for CT45A3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CT45A3 Gene COMPARTMENTS Subcellular localization image for CT45A3 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CT45A3 Gene

Pathways for CT45A3 Gene

SuperPathways for CT45A3 Gene

No Data Available

Interacting Proteins for CT45A3 Gene

Selected Interacting proteins: Q8NHU0-CT453_HUMAN for CT45A3 Gene via UniProtKB I2D

Gene Ontology (GO) - Biological Process for CT45A3 Gene

None

No data available for Pathways by source for CT45A3 Gene

Transcripts for CT45A3 Gene

mRNA/cDNA for CT45A3 Gene

(5) Additional mRNA sequences :
(4) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CT45A3 Gene

Cancer/testis antigen family 45, member A3:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CT45A3

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CT45A3
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CT45A3 Gene

No ASD Table

Relevant External Links for CT45A3 Gene

GeneLoc Exon Structure for
CT45A3
ECgene alternative splicing isoforms for
CT45A3

Expression for CT45A3 Gene

mRNA expression in normal human tissues for CT45A3 Gene

mRNA differential expression in normal tissues according to GTEx for CT45A3 Gene

This gene is overexpressed in Testis (35.5).

SOURCE GeneReport for Unigene cluster for CT45A3 Gene Hs.535080

mRNA Expression by UniProt/SwissProt for CT45A3 Gene

Q8NHU0-CT453_HUMAN
Tissue specificity: Testis specific. Expressed in cancer cell lines.
genes like me logo Genes that share expressions with CT45A3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for CT45A3 Gene

Orthologs for CT45A3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CT45A3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100609226 35
  • 98.24 (n)
  • 95.24 (a)
Species with no ortholog for CT45A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CT45A3 Gene

ENSEMBL:
Gene Tree for CT45A3 (if available)
TreeFam:
Gene Tree for CT45A3 (if available)

Paralogs for CT45A3 Gene

Paralogs for CT45A3 Gene

Selected SIMAP similar genes for CT45A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CT45A3: view

Variants for CT45A3 Gene

Sequence variations from dbSNP and Humsavar for CT45A3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2446141 -- 135,770,868(-) TTGTC(A/G)CACAT intron-variant
rs6633773 -- 135,775,454(+) TACAA(C/T)GAACT intron-variant
rs113727676 -- 135,771,212(+) CCCCC(A/G)ATTTG intron-variant
rs191497672 -- 135,776,238(+) TAATG(A/G)GTGCA intron-variant
rs200401649 -- 135,775,141(+) GGATC(C/G)CTTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CT45A3 Gene

Variant ID Type Subtype PubMed ID
dgv2477e1 CNV Complex 17122850
esv785 CNV CNV 17122850
esv27752 CNV Gain+Loss 19812545
dgv2479e1 CNV Complex 17122850
esv2740498 CNV Deletion 23290073
nsv517224 CNV Gain+Loss 19592680
nsv527747 CNV Gain 19592680
nsv7105 CNV Loss 18451855
nsv7460 OTHER Inversion 18451855
esv1010013 CNV Gain 20482838
nsv9976 CNV Gain+Loss 18304495
nsv215 CNV Loss 15895083
dgv2480e1 CNV Complex 17122850
essv24688 CNV CNV 17122850
nsv469568 CNV Gain 16826518
nsv471605 CNV Gain+Loss 15918152

Relevant External Links for CT45A3 Gene

HapMap Linkage Disequilibrium report
CT45A3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CT45A3 Gene

Disorders for CT45A3 Gene

No disorders were found for CT45A3 Gene.

No data available for UniProtKB/Swiss-Prot for CT45A3 Gene

Publications for CT45A3 Gene

  1. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. (PMID: 15905330) Chen Y.-T. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2005) 2 3 4
  2. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for CT45A3 Gene

Sources for CT45A3 Gene

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