Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CST9L Gene

protein-coding   GIFtS: 50
GCID: GC20M023545

Cystatin 9-Like

(Previous name: cystatin 9 (mouse)-like)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cystatin 9-Like1 2
Cystatin 9 (Mouse)-Like1
CTES7B2
bA218C14.12
cystatin-9-like2
testatin2

External Ids:    HGNC: 162331   Entrez Gene: 1288212   Ensembl: ENSG000001014357   UniProtKB: Q9H4G13   

Export aliases for CST9L gene to outside databases

Previous GC identifers: GC20M023533 GC20M023493 GC20M023540 GC20M023506


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CST9L Gene:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory
activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type
2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found
in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the
type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar
to mouse cystatin 9. Based on its testis-specific expression, it is likely to have a role in tissue
reorganization during early testis development. (provided by RefSeq, Jul 2008)

GeneCards Summary for CST9L Gene:
CST9L (cystatin 9-like) is a protein-coding gene. Diseases associated with CST9L include epididymitis. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CST9.

Gene Wiki entry for CST9L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011387.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the CST9L gene promoter:
         SRY   ISGF-3   POU2F1   POU2F1a   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCST9L promoter sequence
   Search Chromatin IP Primers for CST9L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CST9L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.21   Ensembl cytogenetic band:  20p11.21   HGNC cytogenetic band: 20p11.21

CST9L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CST9L gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M023545:  view genomic region     (about GC identifiers)

Start:
23,545,369 bp from pter      End:
23,549,386 bp from pter
Size:
4,018 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CST9L_HUMAN, Q9H4G1 (See protein sequence)
Recommended Name: Cystatin-9-like precursor  
Size: 147 amino acids; 17276 Da
Secondary accessions: B2R5A1

Explore the universe of human proteins at neXtProt for CST9L: NX_Q9H4G1

Explore proteomics data for CST9L at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn117, Asn139

  • See CST9L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_542177.1  
    ENSEMBL proteins: 
     ENSP00000366178  

    CST9L Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CST9L
    OriGene Protein Over-expression Lysate for CST9L
    OriGene MassSpec for CST9L
    OriGene Custom Protein Services for CST9L
    GenScript Custom Purified and Recombinant Proteins Services for CST9L
    Novus Biologicals CST9L Protein
    Novus Biologicals CST9L Lysate
    Sino Biological Recombinant Protein for CST9L
    Sino Biological Cell Lysate for CST9L
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CST9L

    CST9L Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CST9L
    OriGene Custom Antibody Services for CST9L
    Novus Biologicals CST9L Antibody
    Abcam antibodies for CST9L
    Cloud-Clone Corp. Antibodies for CST9L
    Search ThermoFisher Antibodies for CST9L
    LSBio Antibodies in human, mouse, rat for CST9L

    CST9L Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CST9L
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CST9L
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CST9L
    Cloud-Clone Corp. CLIAs for CST9L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR000010 Prot_inh_cystat
     IPR027213 CST9_like
     IPR027214 Cystatin

    Graphical View of Domain Structure for InterPro Entry Q9H4G1

    ProtoNet protein and cluster: Q9H4G1

    2 Blocks protein domains:
    IPB000010 Cysteine protease inhibitor
    IPB003243 Proteinase inhibitor I25A and I25B


    UniProtKB/Swiss-Prot: CST9L_HUMAN, Q9H4G1
    Similarity: Belongs to the cystatin family


    CST9L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004869cysteine-type endopeptidase inhibitor activity IEA--
         
    CST9L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CST9L:
     Increased G2M DNA content 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Cst9):
     normal 

    CST9L for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for CST9L: Cst9tm1Aw Cst9tm1Nnkj

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CST9L
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CST9L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CST9L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CST9L

    miRNA
    Products:
        
    miRTarBase miRNAs that target CST9L:
    hsa-mir-335-5p (MIRT018903), hsa-mir-132-3p (MIRT021779)

    Block miRNA regulation of human, mouse, rat CST9L using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CST9L
    SwitchGear 3'UTR luciferase reporter plasmidCST9L 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CST9L
    Predesigned siRNA for gene silencing in human, mouse, rat CST9L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CST9L

    Clone
    Products:
         
    OriGene clones in human, mouse for CST9L (see all 5)
    OriGene ORF clones in mouse, rat for CST9L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CST9L
    Sino Biological Human cDNA Clone for CST9L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CST9L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CST9L

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CST9L
    Browse ESI BIO Cell Lines and PureStem Progenitors for CST9L 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CST9L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CST9L_HUMAN, Q9H4G1: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    CST9L for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CST9L
    Interactions:

        Search GeneGlobe Interaction Network for CST9L

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CST9L (ENSP000003661784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCR5ENSP000002923034STRING: ENSP00000292303
    SLC22A2ENSP000003559204STRING: ENSP00000355920
    TAB2ENSP000002863324STRING: ENSP00000286332
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CST9L

    1 Novoseek inferred chemical compound relationship for CST9L gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cysteine 58.4 3 11756564 (1), 12586767 (1), 12644294 (1)



    CST9L for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CST9L gene: 
    NM_080610.2  

    Unigene Cluster for CST9L:

    Cystatin 9-like
    Hs.121554  [show with all ESTs]
    Unigene Representative Sequence: NM_080610
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000376979(uc002wtk.4)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CST9L using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CST9L
    SwitchGear 3'UTR luciferase reporter plasmidCST9L 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CST9L
    Predesigned siRNA for gene silencing in human, mouse, rat CST9L
    Clone
    Products:
         
    OriGene clones in human, mouse for CST9L (see all 5)
    OriGene ORF clones in mouse, rat for CST9L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CST9L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CST9L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CST9L
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CST9L
    OriGene qSTAR qPCR primer pairs in human, mouse for CST9L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CST9L
      QuantiTect SYBR Green Assays in human, mouse, rat CST9L
      QuantiFast Probe-based Assays in human, mouse, rat CST9L

    Additional mRNA sequence: 

    AK312112.1 AY358615.1 BC029656.1 

    1 DOTS entry:

    DT.409828 

    Selected AceView cDNA sequences (see all 32):

    AI631708 BC029656 AA608859 AA496078 AI638675 AY358615 AW572915 BX380551 
    NM_080610 BE500968 AA973942 AA758532 BX104050 AF494536 BI825261 AA968716 
    BX402568 AA911102 AW104268 AA812885 AW024125 BP369653 BE041425 AA934362 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CST9L expression in normal human tissues (normalized intensities)      CST9L embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGTGTAGAT
    CST9L Expression
    About this image


    CST9L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Mature Sertoli Cells Seminiferous Tubules
     
     Gonad
             XY Germ Cells Testis Cord
    CST9L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CST9L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.121554
        Custom PCR Arrays for CST9L
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CST9L
    OriGene qSTAR qPCR primer pairs in human, mouse for CST9L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CST9L
    QuantiTect SYBR Green Assays in human, mouse, rat CST9L
    QuantiFast Probe-based Assays in human, mouse, rat CST9L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CST9L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and mouse.

    Orthologs for CST9L gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cst91 , 5 cystatin 91, 5 64.42(n)1
    56.73(a)1
      2 (73.58 cM)5
    130131  NM_009979.11  NP_034109.11 
     1488351475 


    ENSEMBL Gene Tree for CST9L (if available)
    TreeFam Gene Tree for CST9L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CST9L gene
    CST92  
    5 SIMAP similar genes for CST9L using alignment to 1 protein entry:     CST9L_HUMAN:
    CST9LP1    CST9    CSTL1    CST2    CST11

    CST9L for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CST9L
    PGOHUM00000247611


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CST9L (see all 209)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1380774411,2
    --23544871(+) GATGCA/TGTTCT 1 -- ds50010--------
    rs1145848171,2
    F--23544977(+) AACATT/CTCTAA 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs60760921,2
    H--23545029(+) TTTTAC/GGAGGG 1 -- ds50014Minor allele frequency- G:0.00NS EA 420
    rs22955601,2
    C,F,A,H--23545056(+) TCTTCT/CGCCCA 1 -- ds500127Minor allele frequency- C:0.43EA NS NA CSA WA 3965
    rs22082821,2
    C,H--23545099(+) GCCACC/TCTTCA 1 -- ds500113Minor allele frequency- T:0.04NA WA CSA EA 376
    rs753672591,2
    F--23545159(+) TCCAGG/ACACAT 1 -- ds50011Minor allele frequency- A:0.05WA 118
    rs1437696411,2
    --23545188(+) TAGTCA/GTTGCA 1 -- ds50010--------
    rs1463560111,2
    --23545303(+) CTTGTC/TTGCCC 1 -- ds50010--------
    rs1911470471,2
    --23545468(+) TGCAAA/TATAGG 1 -- ut310--------
    rs1836945861,2
    C--23545539(+) GTCCAC/TGGAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CST9L (23545369 - 23549386 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CST9L:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv458949CNV Gain19166990
    dgv4559n71CNV Gain21882294
    nsv470544CNV Gain18288195
    nsv912820CNV Gain+Loss21882294
    esv7185OTHER Inversion19470904

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CST9L
    DNA2.0 Custom Variant and Variant Library Synthesis for CST9L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for CST9L:    About MalaCards
    epididymitis


    CST9L for disorders           About GeneDecksing

    Genetic Association Database (GAD): CST9L
    Human Genome Epidemiology (HuGE) Navigator: CST9L (1 document)

    Export disorders for CST9L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CST9L gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with CST9L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins. (PubMed id 20565543)1, 3 Frygelius J....TAPhAPnen V. (amp 2010)
    2. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)1, 4 Hwang S.J....Fox C.S. (BMC Med. Genet. 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    7. Isolation of the human testatin gene and analysis in patients with abnormal gonadal development. (PubMed id 11756564)1, 9 Eriksson A....Nordqvist K. (Mol. Hum. Reprod. 2002)
    8. A new subgroup of the family 2 cystatins. (PubMed id 12644294)1, 9 Cornwall G.A. and Hsia N. (Mol. Cell. Endocrinol. 2003)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 128821 HGNC: 16233 AceView: CST9LandCST9 Ensembl:ENSG00000101435 euGenes: HUgn128821
    ECgene: CST9L H-InvDB: CST9L

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CST9L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CST9L gene:
    Search GeneIP for patents involving CST9L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CST9L   OriGene RNAi products in human, mouse, rat for CST9L  
     OriGene qPCR primer pairs and template standards for CST9L   OriGene Protein Over-expression Lysate for CST9L  
     OriGene MassSpec something-or-other for CST9L   OriGene clones in human, mouse for CST9L  
     OriGene qSTAR qPCR primer pairs in human, mouse for CST9L   OriGene Purified Protein for CST9L  
     OriGene ORF clones in mouse, rat for CST9L   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CST9L   OriGene Custom Protein Services for CST9L  

     
     
     Block miRNA regulation of human, mouse, rat CST9L using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CST9L
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CST9L Predesigned siRNA for gene silencing in human, mouse, rat CST9L
     QuantiFast Probe-based Assays in human, mouse, rat CST9L QuantiTect SYBR Green Assays in human, mouse, rat CST9L
     Custom PCR Arrays for CST9L Search Chromatin IP Primers for CST9L
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CST9L  Search GeneGlobe Interaction Network for CST9L
     Regulatory tfbs in CST9L promoter
     GenScript Custom Purified and Recombinant Proteins Services for CST9L GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CST9L
     GenScript Custom Assay Services for CST9L GenScript Custom overexpressing Cell Line Services for CST9L
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CST9L
     Proteins for CST9L
     Cell Lysates for CST9L
     cDNA Clones for CST9L
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CST9L antibodies
     CST9L proteins
     CST9L lysates
     Antibodies for CST9L
     See all of Abcam's Antibodies, Kits and Proteins for CST9L
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CST9L
     Antibodies for CST9L
     ELISAs for CST9L
     CLIAs for CST9L



     Browse ESI BIO Cell Lines and PureStem Progenitors for CST9L
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CST9L
     SwitchGear 3'UTR luciferase reporter plasmids for CST9L
     SwitchGear Promoter luciferase reporter plasmids for CST9L
     Search ThermoFisher Antibodies for CST9L
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CST9L
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CST9L
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CST9L
     LSBio Antibodies in human, mouse, rat for CST9L
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CST9L gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4