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CST7 Gene

protein-coding   GIFtS: 54
GCID: GC20P024924

Cystatin F (Leukocystatin)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cystatin F (Leukocystatin)1 2     cystatin-F2
Cystatin-Like Metastasis-Associated Protein2 3     leukocystatin2
CMAP2 3     Cystatin-73
cystatin-72     Leukocystatin3

External Ids:    HGNC: 24791   Entrez Gene: 85302   Ensembl: ENSG000000779847   OMIM: 6032535   UniProtKB: O760963   

Export aliases for CST7 gene to outside databases

Previous GC identifers: GC20P024917 GC20P024877


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CST7 Gene:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory
activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type
2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found
in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a
putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression
of the protein has been observed in various human cancer cell lines established from malignant tumors. (provided
by RefSeq, Jul 2008)

GeneCards Summary for CST7 Gene:
CST7 (cystatin F (leukocystatin)) is a protein-coding gene. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity and endopeptidase inhibitor activity. An important paralog of this gene is CST6.

UniProtKB/Swiss-Prot: CYTF_HUMAN, O76096
Function: Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in
immune regulation through inhibition of a unique target in the hematopoietic system

Gene Wiki entry for CST7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011387.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the CST7 gene promoter:
         Bach1   Sox5   NF-E2 p45   Roaz   AREB6   PPAR-gamma1   Sox9   PPAR-gamma2   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCST7 promoter sequence
   Search Chromatin IP Primers for CST7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CST7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.21   Ensembl cytogenetic band:  20p11.21   HGNC cytogenetic band: 20p11.21

CST7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CST7 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P024924:  view genomic region     (about GC identifiers)

Start:
24,929,866 bp from pter      End:
24,940,564 bp from pter
Size:
10,699 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CYTF_HUMAN, O76096 (See protein sequence)
Recommended Name: Cystatin-F precursor  
Size: 145 amino acids; 16454 Da
Subunit: Homodimer; disulfide-linked
Sequence caution: Sequence=AAH15507.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAP88827.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAA34941.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAB11886.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened; Sequence=CAB75498.2; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for CST7:
2CH9 (3D)    
Secondary accessions: Q6FH95 Q7Z4J8 Q9UED4

Explore the universe of human proteins at neXtProt for CST7: NX_O76096

Explore proteomics data for CST7 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn62, Asn115

  • See CST7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003641.3  
    ENSEMBL proteins: 
     ENSP00000420384   ENSP00000366031  

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    Cloud-Clone Corp. Proteins for CST7

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000010 Prot_inh_cystat
     IPR027214 Cystatin

    Graphical View of Domain Structure for InterPro Entry O76096

    ProtoNet protein and cluster: O76096

    2 Blocks protein domains:
    IPB000010 Cysteine protease inhibitor
    IPB003243 Proteinase inhibitor I25A and I25B


    UniProtKB/Swiss-Prot: CYTF_HUMAN, O76096
    Similarity: Belongs to the cystatin family


    Find genes that share domains with CST7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CYTF_HUMAN, O76096
    Function: Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in
    immune regulation through inhibition of a unique target in the hematopoietic system

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004866endopeptidase inhibitor activity TAS9632704
    GO:0004869cysteine-type endopeptidase inhibitor activity IEA--
    GO:0005515protein binding IPI18256700
         
    Find genes that share ontologies with CST7           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Cst7):
     normal 

    Find genes that share phenotypes with CST7           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cst7tm1Ayr for CST7

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CST7
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CST7

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CYTF_HUMAN, O76096: Secreted. Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    lysosome2
    cytosol1
    mitochondrion1
    vacuole1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with CST7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including CST7: 
              Tumor Metastasis in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for CST7

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for CST7 (O760961, 2, 3 ENSP000003660314) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTSCP536341, 2, 3, ENSP000002272664EBI-2807448,EBI-1047323 MINT-6179696 MINT-6179710 I2D: score=2 STRING: ENSP00000227266
    CTSBP078583, ENSP000003420704I2D: score=2 STRING: ENSP00000342070
    CTSLP077113, ENSP000003453444I2D: score=2 STRING: ENSP00000345344
    SH2D4AENSP000002658074STRING: ENSP00000265807
    --ENSP000004079504STRING: ENSP00000407950
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response TAS9632704
    GO:0010951negative regulation of endopeptidase activity TAS9632704

    Find genes that share ontologies with CST7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CST7 (CYTF)

    2 Novoseek inferred chemical compound relationships for CST7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 64.5 4 11079561 (1), 19192250 (1), 12203898 (1)
    cysteine 54.6 8 12423348 (2), 11079561 (1), 19192250 (1), 15752368 (1) (see all 6)



    Find genes that share compounds with CST7           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CST7 gene: 
    NM_003650.3  

    Unigene Cluster for CST7:

    Cystatin F (leukocystatin)
    Hs.143212  [show with all ESTs]
    Unigene Representative Sequence: BQ051877
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480798(uc002wtx.2) ENST00000376835
    miRNA
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    Additional mRNA sequence: 

    AB015225.1 AF031824.1 AF036342.1 BC015507.1 BT009825.1 CR541860.1 CR541878.1 

    3 DOTS entries:

    DT.454133  DT.75104824  DT.75114452 

    Selected AceView cDNA sequences (see all 60):

    BQ707136 AJ712419 AI583980 NM_003650 CR611499 AF031824 AL559379 BQ054230 
    AA984868 AI581497 BQ052118 BM917046 BI837059 BM561663 BX283405 BQ710056 
    BT009825 BI768143 BI833917 BQ053396 AI734965 BP429926 BV205829 BE879283 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CST7    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4
    SP1:                                -         
    SP2:                                          
    SP3:                                          


    ECgene alternative splicing isoforms for CST7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CST7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAGCGCCTC
    CST7 Expression
    About this image


    CST7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 5 entries
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
             Bone marrow-derived hematopoietic stem cells (family)
             Bone Marrow CD34+ Cells   
     
     Yolk Sac (Extraembryonic Tissues)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
     
     Umbilical Cord (Extraembryonic Tissues)
             Cord Blood Natural Killer Cells (CD56+)   
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Spleen (Hematopoietic System)
    CST7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CST7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.143212

    UniProtKB/Swiss-Prot: CYTF_HUMAN, O76096
    Tissue specificity: Primarily expressed in peripheral blood cells and spleen

        Pathway & Disease-focused RT2 Profiler PCR Array including CST7: 
              Tumor Metastasis in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CST7 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cst71 , 5 cystatin F (leukocystatin)1, 5 78.33(n)1
    72.14(a)1
      2 (74.67 cM)5
    130111  NM_009977.31  NP_034107.21 
     1505704155 
    chicken
    (Gallus gallus)
    Aves CST71 cystatin F (leukocystatin) 57.38(n)
    50.71(a)
      416716  NM_001199394.1  NP_001186323.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cst71 cystatin F (leukocystatin) 56.11(n)
    55(a)
      496776  NM_001011317.1  NP_001011317.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CST76
    cystatin F (leukocystatin)
    32(a)
    1 ↔ 1
    Zv9_NA824(102-3411) ENSDARG00000089946


    ENSEMBL Gene Tree for CST7 (if available)
    TreeFam Gene Tree for CST7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CST7 gene
    CST62  
    7 SIMAP similar genes for CST7 using alignment to 1 protein entry:     CYTF_HUMAN:
    CSTL1    KNG1    CST8    CST3    CST6    CST1
    CST5

    Find genes that share paralogs with CST7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CST7 (see all 464)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs61149521,2
    C,F--24927914(+) ggataC/Taaata 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1846233371,2
    --24927925(+) AATGGA/GAAAAC 1 -- us2k10--------
    rs60501931,2
    C,F,H--24927931(+) aaaacA/Tttcca 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1895013981,2
    --24927961(+) TCAATA/GTTGTG 1 -- us2k10--------
    rs1806937501,2
    --24927962(+) CAATGC/TTGTGA 1 -- us2k10--------
    rs1876689091,2
    --24927973(+) AAATGG/TCCATA 1 -- us2k10--------
    rs1383113251,2
    --24928024(+) AAGCTA/GTCATT 1 -- us2k10--------
    rs1894349261,2
    --24928027(+) CTATCA/GTTGAC 1 -- us2k10--------
    rs1817091131,2
    --24928078(+) GGGAAA/CCAAAA 1 -- us2k10--------
    rs1492452911,2
    --24928179(+) AGTAAC/TCAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CST7 (24929866 - 24940564 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CST7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1703823CNV Insertion17803354
    nsv510783CNV Loss20534489
    nsv522873CNV Gain19592680
    nsv524921CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603253    OMIM disorders: --

    5 diseases from the University of Copenhagen DISEASES database for CST7:
    Carpal tunnel syndrome     Neuropathy     Polyneuropathy     Myopathy
    Amyotrophic lateral sclerosis

    Find genes that share disorders with CST7           About GenesLikeMe

    3 Novoseek inferred disease relationships for CST7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    metastasis 11.4 8 12171889 (6), 9892200 (1)
    tumors 0 8 18575712 (4), 12171889 (1), 9892200 (1)
    cancer 0 11 12171889 (3), 9892200 (1), 15212960 (1), 10945474 (1)


    Export disorders for CST7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CST7 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with CST7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor. (PubMed id 9733783)1, 2, 3, 9 Ni J.... Abrahamson M. (J. Biol. Chem. 1998)
    2. Leukocystatin, a new class II cystatin expressed selectively by hematopoietic cells. (PubMed id 9632704)1, 2, 3, 9 Halfon S.... Zurawski G. (J. Biol. Chem. 1998)
    3. Genomic construct and mapping of the gene for CMAP (leukocystatin/cystatin F, CST7) and identification of a proximal novel gene, BSCv (C20orf3). (PubMed id 10945474)1, 2, 9 Morita M.... Nishimura S. (Genomics 2000)
    4. Regulated expression and intracellular localization of cystatin F in human U937 cells. (PubMed id 12423348)1, 2, 9 Nathanson C.M.... Abrahamson M. (Eur. J. Biochem. 2002)
    5. Structural basis of reduction-dependent activation of human cystatin F. (PubMed id 16601115)1, 2, 9 Schuettelkopf A.W.... van Aalten D.M.F. (J. Biol. Chem. 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    8. Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. (PubMed id 15752368)1, 9 Langerholc T....Kos J. (FEBS J. 2005)
    9. Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources. (PubMed id 19192250)1, 9 Colbert J.D....Watts C. (Traffic 2009)
    10. Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis. (PubMed id 18256700)1, 9 Hamilton G....Watts C. (EMBO J. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8530 HGNC: 2479 AceView: CST7 Ensembl:ENSG00000077984 euGenes: HUgn8530
    ECgene: CST7 H-InvDB: CST7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CST7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CST7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CST7 gene:
    Search GeneIP for patents involving CST7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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