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CST2 Gene

protein-coding   GIFtS: 49
GCID: GC20M023805

Cystatin SA

  See CST2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cystatin SA1 2     cystatin-SA2
Cystatin 21 2     Cysteine-Proteinase Inhibitor2
Cystatin S52     Salivary Cysteine (Thiol) Protease Inhibitor2
cystatin-22     Cystatin-23
cystatin-S52     Cystatin-S53

External Ids:    HGNC: 24741   Entrez Gene: 14702   Ensembl: ENSG000001703697   OMIM: 1238565   UniProtKB: P092283   

Export aliases for CST2 gene to outside databases

Previous GC identifers: GC20M023792 GC20M023799 GC20M023752


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CST2 Gene:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members
are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory
activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type
2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found
in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin
locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located
in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and
seminal plasma. (provided by RefSeq, Jul 2008)

GeneCards Summary for CST2 Gene:
CST2 (cystatin SA) is a protein-coding gene. Diseases associated with CST2 include autoimmune polyendocrine syndrome type 1. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CST4.

UniProtKB/Swiss-Prot: CYTT_HUMAN, P09228
Function: Thiol protease inhibitor

Gene Wiki entry for CST2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CST2 gene promoter:
         Zic1   Nkx5-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCST2 promoter sequence
   Search Chromatin IP Primers for CST2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CST2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.21   Ensembl cytogenetic band:  20p11.21   HGNC cytogenetic band: 20p11.2

CST2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CST2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M023805:  view genomic region     (about GC identifiers)

Start:
23,804,404 bp from pter      End:
23,807,368 bp from pter
Size:
2,965 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CYTT_HUMAN, P09228 (See protein sequence)
Recommended Name: Cystatin-SA precursor  
Size: 141 amino acids; 16445 Da
Mass spectrometry: Mass=14336.9856; Mass_error=0.0158; Method=Electrospray; Range=21-141; Source=PubMed:20189825;
Secondary accessions: Q9UCQ7

Explore the universe of human proteins at neXtProt for CST2: NX_P09228

Explore proteomics data for CST2 at MOPED


See CST2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001313.1  
ENSEMBL proteins: 
 ENSP00000307540  

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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3 InterPro protein domains:
 IPR018073 Prot_inh_cystat_CS
 IPR000010 Prot_inh_cystat
 IPR027214 Cystatin

Graphical View of Domain Structure for InterPro Entry P09228

ProtoNet protein and cluster: P09228

2 Blocks protein domains:
IPB000010 Cysteine protease inhibitor
IPB003243 Proteinase inhibitor I25A and I25B


UniProtKB/Swiss-Prot: CYTT_HUMAN, P09228
Similarity: Belongs to the cystatin family


Find genes that share domains with CST2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CYTT_HUMAN, P09228
Function: Thiol protease inhibitor

     Genatlas biochemistry entry for CST2:
cystatin SA,cysteine proteinase inhibitor,found at high levels in saliva,tears,seminal plasma,type 2
family,including two variants cystatin SA1 and cystatin SA2

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004869cysteine-type endopeptidase inhibitor activity IEA--
     
Find genes that share ontologies with CST2           About GenesLikeMe


Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for CST2

miRNA
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miRTarBase miRNAs that target CST2:
hsa-mir-26b-5p (MIRT030133), hsa-mir-335-5p (MIRT018818)

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CYTT_HUMAN, P09228: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
cytosol1
lysosome1
peroxisome1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region ----
GO:0005615extracellular space IDA--

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for CST2 About    
See pathways by source

SuperPathContained pathways About
1Salivary secretion
Salivary secretion0.34


Find genes that share SuperPaths with CST2           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways




1 Kegg Pathway  (Kegg details for CST2):
    Salivary secretion

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CST2
Interactions:

    Search GeneGlobe Interaction Network for CST2

Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001580detection of chemical stimulus involved in sensory perception of bitter taste IDA--
GO:0010951negative regulation of endopeptidase activity TAS3446578

Find genes that share ontologies with CST2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CST2 (CYTT)

2 Novoseek inferred chemical compound relationships for CST2 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
kininogen 73.9 4 2338365 (1), 2107324 (1)
cysteine 72.7 14 12586767 (2), 15196002 (1), 15603510 (1), 9099741 (1) (see all 13)



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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CST2 gene: 
NM_001322.2  

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000304725(uc002wtq.1)
miRNA
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Selected AceView cDNA sequences (see all 25):

NM_001322 CK905411 CK905410 BP334783 BP334327 CB959441 BC062679 BP334323 
BP334646 BP334681 BQ683774 BP334802 BP335077 BP334571 AI521546 BP334367 
BP335021 CD611299 BP334101 AW117764 BM509439 BP334115 BM509192 BP334272 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CST2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GTACACACAC
CST2 Expression
About this image


CST2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 
 Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 4 entries
         hIPS1
CST2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CST2 Protein Expression

UniProtKB/Swiss-Prot: CYTT_HUMAN, P09228
Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level).
Expressed in submandibular gland and parotid gland

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CST2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CST2 gene from Selected species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chicken
(Gallus gallus)
Aves gga-mir-35266
Gallus gallus cystatin C (CST3), mRNA.
37(a)
1 → many
3(14928612-14932913)
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
38(a)
1 → many
4(82204275-82217421)
zebrafish
(Danio rerio)
Actinopterygii cst36
cystatin C (amyloid angiopathy and cerebral hemorr...
30(a)
many ↔ many
13(33900031-33908388) ENSDARG00000007795
        Species with no ortholog for CST2

ENSEMBL Gene Tree for CST2 (if available)
TreeFam Gene Tree for CST2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CST2 gene
CST42  CSTL12  CST82  CST12  CST32  CST52  CST112  
10 SIMAP similar genes for CST2 using alignment to 1 protein entry:     CYTT_HUMAN:
CST1    CST4    CST5    CST3    CST11    CSTL1
CST8    CST6    CST9LP1    CST9L

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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CST2 (see all 261)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs61143181,2
C,F,H--23803966(+) CATTTG/ATCTAT 1 -- ds500120Minor allele frequency- A:0.25NS EA NA WA CSA 2339
rs1426470371,2
--23804046(+) TCCACC/TGAGGC 1 -- ds50010--------
rs781407431,2
C,F--23804104(+) CAGTAG/ACTCAG 1 -- ds50011Minor allele frequency- A:0.02WA 118
rs1506154391,2
C--23804133(+) CTTCCC/TGGGCA 1 -- ds50010--------
rs1894461741,2
C--23804209(+) TCCAGA/CCCCTG 1 -- ds50010--------
rs1397186101,2
--23804243(+) CTCAGA/GCCTCC 1 -- ds50010--------
rs413093451,2
C--23804265(+) CAGCTC/TCCCTG 1 -- ds50014Minor allele frequency- T:0.19CSA WA NA EA 360
rs1115361071,2
C,F--23804296(+) TCAGGT/CCCCAG 1 -- ds50012Minor allele frequency- C:0.03CSA WA 120
rs1497687801,2
C--23804328(+) AAGCAC/GAACAA 1 -- ds50010--------
rs61381231,2
C,F--23804355(+) AACTGC/TAGAAA 1 -- ds50015Minor allele frequency- T:0.07WA NA CSA 129

HapMap Linkage Disequilibrium report for CST2 (23804404 - 23807368 bp)

Structural Variations
     Database of Genomic Variants (DGV) 9 variations for CST2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv436326CNV Deletion17901297
dgv698e201CNV Deletion23290073
dgv783e199CNV Deletion23128226
esv2722309CNV Deletion23290073
esv2722310CNV Deletion23290073
nsv458953CNV Loss19166990
nsv3336CNV Loss18451855
nsv833944CNV Gain17160897
nsv912823CNV Gain21882294

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 123856    OMIM disorders: --

1 disease for CST2:    
About MalaCards
autoimmune polyendocrine syndrome type 1


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Genetic Association Database (GAD): CST2
Human Genome Epidemiology (HuGE) Navigator: CST2 (3 documents)

Export disorders for CST2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CST2 gene, integrated from 10 sources (see all 69):
(articles sorted by number of sources associating them with CST2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S. (PubMed id 1778989)1, 2, 9 Isemura S.... Minakata K. (J. Biochem. 1991)
  2. Sac I Restriction Fragment Length Polymorphism (RFLP) related to the human CST2 gene. (PubMed id 12013824)1, 4, 9 Minaguchi K....Sanada K. (Bull. Tokyo Dent. Coll. 2002)
  3. Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland. (PubMed id 11879580)1, 2, 9 Dickinson D.P.... Hicks M.J. (DNA Cell Biol. 2002)
  4. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
  5. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
  6. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
  9. Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes. (PubMed id 3202964)1, 2 Saitoh E.... Maeda N. (Biol. Chem. Hoppe-Seyler 1988)
  10. Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. (PubMed id 3446578)1, 2 Saitoh E.... Maeda N. (Gene 1987)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1470 HGNC: 2474 AceView: CST2 Ensembl:ENSG00000170369 euGenes: HUgn1470
ECgene: CST2 Kegg: 1470 H-InvDB: CST2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CST2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CST2 gene:
Search GeneIP for patents involving CST2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 EMD Millipore genomic analysis products

  
 Antibodies for CST2 (Cystatin SA)   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Recombinant/Natural Proteins for CST2 (Cystatin SA)   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for CST2   OriGene RNAi products in human, mouse, rat for CST2  
 OriGene qPCR primer pairs and template standards for CST2   OriGene Protein Over-expression Lysate for CST2  
 OriGene MassSpec for CST2   OriGene clones in human, mouse for CST2  
 OriGene qSTAR qPCR primer pairs in human, mouse for CST2   OriGene Purified Protein for CST2  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CST2   OriGene Custom Protein Services for CST2  

 
 
 Block miRNA regulation of human, mouse, rat CST2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CST2
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CST2 Predesigned siRNA for gene silencing in human, mouse, rat CST2
 QuantiFast Probe-based Assays in human, mouse, rat CST2 QuantiTect SYBR Green Assays in human, mouse, rat CST2
 Custom PCR Arrays for CST2 Search Chromatin IP Primers for CST2
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CST2  Search GeneGlobe Interaction Network for CST2
 Regulatory tfbs in CST2 promoter
 GenScript Custom Purified and Recombinant Proteins Services for CST2 GenScript cDNA clones with any tag delivered in your preferred vector for CST2
 GenScript Custom Assay Services for CST2 GenScript Custom overexpressing Cell Line Services for CST2
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for CST2 (CYTT)
 Proteins for CST2
 Cell Lysates for CST2
 cDNA Clones for CST2
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 CST2 antibodies
 CST2 proteins
 CST2 lysates
 Antibodies for CST2
 See all of Abcam's Antibodies, Kits and Proteins for CST2
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for CST2
 Antibodies for CST2
 ELISAs for CST2
 CLIAs for CST2



 Browse ESI BIO Cell Lines and PureStem Progenitors for CST2
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CST2
 SwitchGear 3'UTR luciferase reporter plasmids for CST2
 SwitchGear Promoter luciferase reporter plasmids for CST2
 Search ThermoFisher Antibodies for CST2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CST2
 Browse compounds at ApexBio
 Search Addgene for plasmids for CST2
  Search eBioscience for proteins for CST2
  Search eBioscience for elisas for CST2
  eBioscience FlowRNA Probe Sets
 genOway: Develop your customized and physiologically relevant rodent model for CST2
 antibodies-online antibodies for CST2 (21 products)
 antibodies-online kits for CST2 (5 products)
 antibodies-online peptides for CST2
 antibodies-online proteins for CST2 (10 products)
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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