Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CSRP2BP Gene

protein-coding   GIFtS: 51
GCID: GC20P018066

CSRP2 binding protein
 Explore 1 disease affiliated with
CSRP2BP via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CSRP2BP    

Aliases
for CSRP2BP gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
CSRP2 Binding Protein1 2     CSRP2-Binding Protein2 3
ATAC21 2 3     ATAC Component 2 Homolog2
CRP2BP1 2 3     CRP2 Binding Partner2
KAT141 2     CRP2 Binding Protein2
PRO11941 2     Cysteine-Rich Protein 2-Binding Protein2
DJ717M23.11     CRP2-Binding Partner3
ADA2A-Containing Complex Subunit 22 3     

External Ids:    HGNC: 159041   Entrez Gene: 573252   Ensembl: ENSG000001494747   UniProtKB: Q9H8E83   
ORGUL members:         
NONCODE:n408238    

Export aliases for CSRP2BP gene to outside databases

Previous GC identifers: GC20P018106 GC20P018113


Summaries
for CSRP2BP gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CSRP2BP:
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse
function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to
form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains
an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a
nuclear protein. Alternatively spliced transcript variants have been described. (provided by RefSeq, Jun 2011)

UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May
function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase
activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle

Gene Wiki entry for CSRP2BP


Genomic Views
for CSRP2BP gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CSRP2BP gene promoter:
         N-Myc   USF1   USF-1   GCNF-1   GCNF   Nkx2-5   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CSRP2BP promoter sequence
   Search SABiosciences Chromatin IP Primers for CSRP2BP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSRP2BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.23   Ensembl cytogenetic band:  20p11.23   HGNC cytogenetic band: 20p11.23

CSRP2BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSRP2BP gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P018066:  view genomic region     (about GC identifiers)

Start:
 18,118,499 bp from pter      End:
 18,169,031 bp from pter
Size:
 50,533 bases      Orientation:
 plus strand

Proteins
for CSRP2BP gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8 (See protein sequence)
Recommended Name: Cysteine-rich protein 2-binding protein  
Size: 782 amino acids; 88844 Da
Subunit: Interacts with the LIM 1 domain of CSRP2. Component of the ADA2A-containing complex (ATAC), composed of
CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts
directly with KAT2A, MBIP and WDR5
Subcellular location: Nucleus. Cytoplasm. Note=Mainly nuclear
Sequence caution: Sequence=CAB56651.2; Type=Erroneous gene model prediction;
Secondary accessions: A2A2I5 Q96GW6 Q96IH3 Q9HBF0 Q9UIY5
Alternative splicing: 2 isoforms:  Q9H8E8-1   Q9H8E8-2   (May be due to an intron retention)

Explore the universe of human proteins at neXtProt for CSRP2BP: NX_Q9H8E8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H8E8

    • CSRP2BP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065397.3  
    ENSEMBL proteins: 
     ENSP00000278816   ENSP00000366909   ENSP00000424752   ENSP00000425909   ENSP00000392318  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: CSRP2BP
    OriGene Protein Over-expression Lysate (see all 2): CSRP2BP
    OriGene Custom Protein Services for CSRP2BP 
    GenScript Custom Purified and Recombinant Proteins Services for CSRP2BP
    Novus Biologicals CSRP2BP Protein
    Novus Biologicals CSRP2BP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CSRP2BP

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IPI10924333
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IDA18838386
    GO:0005737cytoplasm IEA--


    CSRP2BP for ontologies           About GeneDecksing



    CSRP2BP Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CSRP2BP 
    GenScript Custom Superior Antibodies Services for CSRP2BP
    Novus Biologicals CSRP2BP Antibodies
    Abcam antibodies for CSRP2BP 
    Uscn Antibodies for CSRP2BP
    Search ThermoFisher Antibodies for CSRP2BP

    Assay Products for CSRP2BP: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CSRP2BP
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CSRP2BP

    Protein Domains /
    Families
    for CSRP2BP gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CSRP2BP for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000182 GNAT_dom
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry Q9H8E8

    ProtoNet protein and cluster: Q9H8E8

    1 Blocks protein family: IPB000182 GCN5-related N-acetyltransferase

    UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
    Similarity: Contains 1 N-acetyltransferase domain


    Function
    for CSRP2BP gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
    Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May
    function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase
    activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle

    miRNA
    Products:            		 OriGene 3'-UTR Clone: CSRP2BP
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSRP2BP
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate CSRP2BP:
    hsa-miR-4309 hsa-miR-4294
    SwitchGear 3'UTR luciferase reporter plasmid: CSRP2BP 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSRP2BP (see all 4)
    OriGene shRNA RFP: CSRP2BP
    OriGene siRNA: CSRP2BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSRP2BP

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CSRP2BP

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CSRP2BP (NM_020536)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSRP2BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRP2BP 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CSRP2BP
    Search LifeMap BioReagents cell lines for CSRP2BP

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRP2BP

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004402histone acetyltransferase activity IDA19103755
    GO:0005515protein binding IPI19060904
    GO:0030274LIM domain binding NAS10924333


    CSRP2BP for ontologies           About GeneDecksing


    Animal Models:
         10 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Csrp2bp):
     cardiovascular system  cellular  craniofacial  embryogenesis  growth/size 
     immune system  mortality/aging  nervous system  skeleton  vision/eye 

    CSRP2BP for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CSRP2BP gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CSRP2BP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/19 Interacting proteins for CSRP2BP (Q9H8E81, 2, 3 ENSP000002788164) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MBIPQ9NS731, 2, 3, ENSP000003244444EBI-750907,EBI-741953 MINT-67943 I2D: score=5 STRING: ENSP00000324444
    CCDC101Q96ES72, 3, ENSP000003161144MINT-8012362 I2D: score=1 STRING: ENSP00000316114
    TADA2AO754783, ENSP000002253964I2D: score=1 STRING: ENSP00000225396
    WDR5P619643, ENSP000003514464I2D: score=1 STRING: ENSP00000351446
    YEATS2Q9ULM33, ENSP000003069834I2D: score=1 STRING: ENSP00000306983
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009790embryo development IEA--
    GO:0016573histone acetylation ----
    GO:0022402cell cycle process IEA--
    GO:0043966histone H3 acetylation IDA18838386


    CSRP2BP for ontologies           About GeneDecksing



    Drugs & Compounds
    for CSRP2BP gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CSRP2BP
    Search CenterWatch for drugs/clinical trials and news about CSRP2BP / CSR2B 

    Transcripts
    for CSRP2BP gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CSRP2BP gene (2 alternative transcripts): 
    NM_020536.4  NM_177926.1  

    Unigene Cluster for CSRP2BP:

    CSRP2 binding protein
    Hs.728790  [show with all ESTs]
    Unigene Representative Sequence: NM_020536
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000278816 ENST00000377681(uc010zru.2) ENST00000464792 ENST00000489422
    ENST00000484001 ENST00000492286 ENST00000489634(uc002wqk.3) ENST00000435364(uc021wbb.1)


    miRNA
    Products:             		 OriGene 3'-UTR Clone: CSRP2BP
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSRP2BP
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate CSRP2BP:
    hsa-miR-4309 hsa-miR-4294
    SwitchGear 3'UTR luciferase reporter plasmid: CSRP2BP 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSRP2BP (see all 4)
    OriGene shRNA RFP: CSRP2BP
    OriGene siRNA: CSRP2BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSRP2BP
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CSRP2BP (NM_020536)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSRP2BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRP2BP 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSRP2BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CSRP2BP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSRP2BP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSRP2BP

    Additional cDNA sequence: 

    AF086492.1 AF252257.1 AK023634.1 AK023759.1 BC007537.1 BC009174.2 NR_028402.2 

    6 DOTS entries:

    DT.99968633  DT.454749  DT.40123286  DT.91931474  DT.120802521  DT.92068206 

    24/174 AceView cDNA sequences (see all 174):

    NM_177926 CB321885 BC007537 AI417332 AF252257 BF478242 AW028835 Z41471 
    AA564115 AI650639 T16637 BM702555 BI754622 BU620288 NM_020536 BQ071298 
    BC009174 AW001621 N67977 BQ710886 AW516861 AA935033 AI458929 AF086492 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for CSRP2BP (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                                                                          -                                                               
    SP2:                                                                                                                    -     -               
    SP3:                                                                          -                                                               
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for CSRP2BP

    Expression
    for CSRP2BP gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CSRP2BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGTCCCAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CSRP2BP expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TrophoblastMural TrophectodermMural Trophectoderm CellsExtraembryonic Tissues
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CSRP2BP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CSRP2BP

    SOURCE GeneReport for Unigene cluster: Hs.728790

    UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
    Tissue specificity: Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High
    expression in skeletal muscle and heart. Lower expression in lung

        SABiosciences Expression via Pathway-Focused PCR Array including CSRP2BP: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSRP2BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CSRP2BP
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSRP2BP
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSRP2BP
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRP2BP

    Orthologs
    for CSRP2BP gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CSRP2BP gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Csrp2bp1 , 5 cysteine and glycine-rich protein 2 binding protein1, 5 87.55(n)1
    95.38(a)1    		   2 (71.01 cM)5
    2287141  NM_181417.31  NP_852082.21 
     1443689835 
    chicken
    (Gallus gallus)    		 Aves CSRP2BP1 CSRP2 binding protein 79.44(n)
    88.21(a)    		   416721  NM_001199441.1  NP_001186370.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CSRP2BP6
    		 --
    		 82(a)
    		 1 ↔ 1
    		 4(74510586-74528137)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.137792 Transcribed sequence 77.34(n)    BX737607.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii csrp2bp1 cysteine and glycine-rich protein 2 binding protein 68.41(n)
    75.49(a)    		   562636  NM_001002699.2  NP_001002699.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG104143
    Atac21    		 ATAC complex component 21 41(a)3
    45.48(n)1
    38.41(a)1    		   36F73
    351131  NM_136045.21  NP_609889.11 


    ENSEMBL Gene Tree for CSRP2BP (if available)
    TreeFam Gene Tree for CSRP2BP (if available) 

    Paralogs
    for CSRP2BP gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CSRP2BP gene

    CSRP2BP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CSRP2BP
    PGOHUM00000232910


    Genomic Variants
    for CSRP2BP gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/77 NCBI SNPs in CSRP2BP are shown (see all 77)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs575080151,2
    		C,F,--18084583(+) TGCCTG/TCCTTG 1 -- us2k16Minor allele frequency- T:0.25WA NA CSA 246
    rs774872231,2
    		F,--18085045(+) AACTTT/CAAAAA 1 -- us2k12Minor allele frequency- C:0.10WA NA 238
    rs12052131,2
    		C,A,--18085091(+) aatccG/Agcact 1 -- us2k13Minor allele frequency- A:0.14NA EA 242
    rs761688701,2
    		--18085707(+) AAATTC/TGGAAA 1 -- ut511Minor allele frequency- T:0.01EA 120
    rs758397271,2
    		C,--18086358(+) AGTGCA/CAAAAA 2 K Q mis10--------
    rs119066771,2
    		C,F,H,--18086457(+) TGAATG/ATAAAA 1 -- int16Minor allele frequency- A:0.02NS EA NA WA 540
    rs1148820721,2
    		C,F,--18086521(+) TTTATA/GTAAAA 1 -- int11Minor allele frequency- G:0.02WA 118
    rs73511731,2
    		H--18086595(+) TTTGGT/GGGTAA 2 -- int1 us2k14Minor allele frequency- G:0.00NS EA 418
    rs756788411,2
    		F,--18086660(+) TTTTTC/TTAACA 2 -- int1 us2k11Minor allele frequency- T:0.02WA 118
    rs1877757011,2
    		--18120883(+) TGCAGG/TTGGGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for CSRP2BP (18118499 - 18169031 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CSRP2BP: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSRP2BP
    DNA2.0 Custom Variant and Variant Library Synthesis for CSRP2BP

    Disorders / Diseases
    for CSRP2BP gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CSRP2BP for disorders           About GeneDecksing

    1 disease for CSRP2BP:    About MalaCards
    anorexia nervosa

    Human Genome Epidemiology (HuGE) Navigator: CSRP2BP (1 document)

    Export disorders for CSRP2BP gene to outside databases

    Publications
    for CSRP2BP gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CSRP2BP gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with CSRP2BP)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein. (PubMed id 10924333)1, 2, 3, 9 Weiskirchen R. and Gressner A.M. (2000)
    2. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. (PubMed id 19103755)1, 2, 3 Guelman S.... Zha J. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. WD repeat-containing protein 5, a ubiquitously express ed histone methyltransferase adaptor protein, regulates smooth muscle cell-selec tive gene activation through interaction with pituitary homeobox 2. (PubMed id 21531708)1 Gan Q....Owens G.K. (2011)
    7. Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
    8. A genome-wide association study on common SNPs and ra re CNVs in anorexia nervosa. (PubMed id 21079607)1 Wang K....Hakonarson H. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)

    External Searches for CSRP2BP gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CSRP2BP gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57325 HGNC: 15904 AceView: CSRP2BP Ensembl:ENSG00000149474 euGenes: HUgn57325
    ECgene: CSRP2BP H-InvDB: CSRP2BP

    Other Databases showing CSRP2BP gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CSRP2BP gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CSRP2BP Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CSRP2BP gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CSRP2BP gene:
    Search GeneIP for patents involving CSRP2BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for CSRP2BP gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for CSRP2BP  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSRP2BP   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSRP2BP  
     OriGene Protein Over-expression Lysate for CSRP2BP   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for CSRP2BP   OriGene 3'-UTR Clone for CSRP2BP  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP2BP  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for CSRP2BP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CSRP2BP   OriGene Custom Protein Services for CSRP2BP  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CSRP2BP
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSRP2BP
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSRP2BP
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSRP2BP
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSRP2BP
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSRP2BP
     GenScript Custom Purified and Recombinant Proteins Services for CSRP2BP GenScript cDNA clones with any tag delivered in your preferred vector for CSRP2BP
     GenScript Custom Assay Services for CSRP2BP GenScript Custom Superior Antibodies Services for CSRP2BP
     GenScript Custom overexpressing Cell Line Services for CSRP2BP CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CSRP2BP promoter
     Search Chromatin IP Primers for CSRP2BP
     RT2 qPCR Primer Assay in human, mouse, rat CSRP2BP
     GNC Network for CSRP2BP
     SABiosciences PCR Arrays including human, mouse, rat CSRP2BP
     Search Tocris compounds for CSRP2BP
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CSRP2BP antibodies
     CSRP2BP proteins
     CSRP2BP lysates
     Antibodies for CSRP2BP
     See all of Abcam's Antibodies, Kits and Proteins for CSRP2BP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     CSRP2BP Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for CSRP2BP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRP2BP
     SwitchGear 3'UTR luciferase reporter plasmids for CSRP2BP
     SwitchGear Promoter luciferase reporter plasmids for CSRP2BP
     Search ThermoFisher Antibodies for CSRP2BP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRP2BP
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      CSRP2BP gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4