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CSRP2BP Gene

protein-coding   GIFtS: 53
GCID: GC20P018066

CSRP2 Binding Protein

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CSRP2 Binding Protein1 2     PRO11942
ATAC22 3     ATAC Component 2 Homolog2
CRP2BP2 3     CRP2 Binding Partner2
ADA2A-Containing Complex Subunit 22 3     CRP2 Binding Protein2
CSRP2-Binding Protein2 3     Cysteine-Rich Protein 2-Binding Protein2
ATAC Component 2 Homolog (Drosophila)1     dJ717M23.12
Cysteine Rich Protein 2 Binding Protein1     CRP2-Binding Partner3
KAT142     

External Ids:    HGNC: 159041   Entrez Gene: 573252   Ensembl: ENSG000001494747   UniProtKB: Q9H8E83   

Export aliases for CSRP2BP gene to outside databases

Previous GC identifers: GC20P018106 GC20P018113


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CSRP2BP Gene:
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse
function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins
to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and
contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is
predominantly a nuclear protein. Alternatively spliced transcript variants have been described. (provided by
RefSeq, Jun 2011)

GeneCards Summary for CSRP2BP Gene:
CSRP2BP (CSRP2 binding protein) is a protein-coding gene. Diseases associated with CSRP2BP include anorexia nervosa. GO annotations related to this gene include histone acetyltransferase activity and LIM domain binding.

UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone
acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of
the cell cycle

Gene Wiki entry for CSRP2BP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CSRP2BP gene promoter:
         N-Myc   USF1   USF-1   GCNF-1   GCNF   Nkx2-5   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSRP2BP promoter sequence
   Search Chromatin IP Primers for CSRP2BP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSRP2BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.23   Ensembl cytogenetic band:  20p11.23   HGNC cytogenetic band: 20p11.23

CSRP2BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSRP2BP gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P018066:  view genomic region     (about GC identifiers)

Start:
18,118,762 bp from pter      End:
18,169,031 bp from pter
Size:
50,270 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8 (See protein sequence)
Recommended Name: Cysteine-rich protein 2-binding protein  
Size: 782 amino acids; 88844 Da
Subunit: Interacts with the LIM 1 domain of CSRP2. Component of the ADA2A-containing complex (ATAC), composed of
CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts
directly with KAT2A, MBIP and WDR5
Sequence caution: Sequence=CAB56651.2; Type=Erroneous gene model prediction;
Secondary accessions: A2A2I5 Q96GW6 Q96IH3 Q9HBF0 Q9UIY5
Alternative splicing: 2 isoforms:  Q9H8E8-1   Q9H8E8-2   (May be due to an intron retention)

Explore the universe of human proteins at neXtProt for CSRP2BP: NX_Q9H8E8

Explore proteomics data for CSRP2BP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CSRP2BP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065397.3  
    ENSEMBL proteins: 
     ENSP00000424752   ENSP00000392318   ENSP00000366909   ENSP00000425909  
    Reactome Protein details: Q9H8E8

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000182 GNAT_dom
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry Q9H8E8

    ProtoNet protein and cluster: Q9H8E8

    1 Blocks protein domain: IPB000182 GCN5-related N-acetyltransferase

    UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
    Similarity: Contains 1 N-acetyltransferase domain


    CSRP2BP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CSR2B_HUMAN, Q9H8E8
    Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
    May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone
    acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of
    the cell cycle

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004402histone acetyltransferase activity IDA19103755
    GO:0005515protein binding IPI16189514
    GO:0008080N-acetyltransferase activity ----
    GO:0030274LIM domain binding NAS10924333
         
    CSRP2BP for ontologies           About GeneDecksing


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Csrp2bp):
     cardiovascular system  cellular  craniofacial  embryogenesis  growth/size/body 
     immune system  mortality/aging  nervous system  skeleton  vision/eye 

    CSRP2BP for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CSRP2BP
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CSRP2BP
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    miRNA
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    miRTarBase miRNAs that target CSRP2BP:
    hsa-mir-26a-5p (MIRT050132)

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    2 qRT-PCR Assays for microRNAs that regulate CSRP2BP:
    hsa-miR-4309 hsa-miR-4294
    SwitchGear 3'UTR luciferase reporter plasmidCSRP2BP 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: CSRP2BP (NM_020536)
    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CSR2B_HUMAN, Q9H8E8: Nucleus. Cytoplasm. Note=Mainly nuclear
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IPI10924333
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IDA18838386
    GO:0005737cytoplasm IEA--

    CSRP2BP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CSRP2BP About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for CSRP2BP
        HATs acetylate histones



    CSRP2BP for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including CSRP2BP: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CSRP2BP

    Selected Interacting proteins for CSRP2BP (Q9H8E81, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MBIPQ9NS731, 2, 3EBI-750907,EBI-741953 MINT-67943 I2D: score=5 
    CCDC101Q96ES72, 3MINT-8012362 I2D: score=1 
    CSRP2Q165273I2D: score=2 
    DR1Q016583I2D: score=1 
    HCFC1P516103I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle IEA--
    GO:0006325chromatin organization TAS--
    GO:0009790embryo development IEA--
    GO:0016573histone acetylation ----
    GO:0022402cell cycle process ----

    CSRP2BP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CSRP2BP (CSR2B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CSRP2BP gene (2 alternative transcripts): 
    NM_020536.4  NM_177926.1  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000464792 ENST00000489422 ENST00000484001 ENST00000492286 ENST00000435364(uc021wbb.1)
    ENST00000377681(uc010zru.2) ENST00000489634(uc002wqk.3)
    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate CSRP2BP:
    hsa-miR-4309 hsa-miR-4294
    SwitchGear 3'UTR luciferase reporter plasmidCSRP2BP 3' UTR sequence
    Inhib. RNA
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    OriGene qPCR primer pairs and template standards for CSRP2BP
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CSRP2BP
      QuantiTect SYBR Green Assays in human, mouse, rat CSRP2BP
      QuantiFast Probe-based Assays in human, mouse, rat CSRP2BP

    Selected AceView cDNA sequences (see all 174):

    BQ710886 AW005678 AF086492 AI650639 AU140233 AY358666 F11249 NM_020536 
    AI417332 N67977 BQ434869 AA935033 AI458929 AW001621 BC009174 CB321885 
    BI754622 BU620288 NM_177926 AA564115 AW028835 BM702555 Z41471 BM552422 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CSRP2BP (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                                                                          -                                                               
    SP2:                                                                                                                    -     -               
    SP3:                                                                          -                                                               
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for CSRP2BP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CSRP2BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCCCAAA
    CSRP2BP Expression
    About this image


    CSRP2BP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
    CSRP2BP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CSRP2BP Protein Expression

    UniProtKB/Swiss-Prot: CSR2B_HUMAN, Q9H8E8
    Tissue specificity: Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High
    expression in skeletal muscle and heart. Lower expression in lung

        Pathway & Disease-focused RT2 Profiler PCR Array including CSRP2BP: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

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    QuantiTect SYBR Green Assays in human, mouse, rat CSRP2BP
    QuantiFast Probe-based Assays in human, mouse, rat CSRP2BP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRP2BP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CSRP2BP gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Csrp2bp1 , 5 cysteine and glycine-rich protein 2 binding protein1, 5 87.55(n)1
    95.38(a)1
      2 (71.01 cM)5
    2287141  NM_181417.31  NP_852082.21 
     1443689835 
    chicken
    (Gallus gallus)
    Aves CSRP2BP1 CSRP2 binding protein 79.56(n)
    88.93(a)
      416721  NM_001199441.1  NP_001186370.1 
    lizard
    (Anolis carolinensis)
    Reptilia CSRP2BP6
    CSRP2 binding protein
    82(a)
    1 ↔ 1
    4(74504903-74529745)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.137792 Transcribed sequence 77.34(n)    BX737607.1 
    zebrafish
    (Danio rerio)
    Actinopterygii csrp2bp1 cysteine and glycine-rich protein 2 binding protein 68.41(n)
    75.39(a)
      562636  NM_001002699.2  NP_001002699.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104143   -- 41(a)   36F7   --


    ENSEMBL Gene Tree for CSRP2BP (if available)
    TreeFam Gene Tree for CSRP2BP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CSRP2BP gene
    1 SIMAP similar gene for CSRP2BP using alignment to 3 protein entries:     CSR2B_HUMAN (see all proteins):
    PET117

    CSRP2BP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CSRP2BP
    PGOHUM00000232910


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CSRP2BP (see all 1017)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1877757011,2
    --18083691(+) TGCAGG/TTGGGG 1 -- us2k10--------
    rs1909670341,2
    --18083746(+) CAAGGA/GTGCAT 1 -- us2k10--------
    rs1824924981,2
    C--18083838(+) GAGGAA/GGTCCA 1 -- us2k10--------
    rs1142730321,2
    C,F--18083954(+) TCTATA/GTAGCC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs755904851,2
    C--18084289(+) AAAAAA/CCAATA 1 -- us2k11Minor allele frequency- C:0.00WA 2
    rs2002576561,2
    --18084493(+) TTTTT-/TTTA  
            
    TTTTT
    1 -- us2k10--------
    rs61363081,2
    C--18084503(+) TTTTTA/TTTTTT 1 -- us2k10--------
    rs575080151,2
    C,F--18084583(+) TGCCTG/TCCTTG 1 -- us2k16Minor allele frequency- T:0.25WA NA CSA 246
    rs1444346351,2
    --18084650(+) AACCTG/TTAGAG 1 -- us2k10--------
    rs1483940051,2
    C--18084808(+) TTTTCC/TGCTGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CSRP2BP (18118762 - 18169031 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CSRP2BP:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833933CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for CSRP2BP:    
    About MalaCards
    anorexia nervosa


    CSRP2BP for disorders           About GeneDecksing

    Genetic Association Database (GAD): CSRP2BP
    Human Genome Epidemiology (HuGE) Navigator: CSRP2BP (1 document)

    Export disorders for CSRP2BP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CSRP2BP gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with CSRP2BP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein. (PubMed id 10924333)1, 2, 3, 9 Weiskirchen R. and Gressner A.M. (Biochem. Biophys. Res. Commun. 2000)
    2. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. (PubMed id 19103755)1, 2, 3 Guelman S.... Zha J. (Mol. Cell. Biol. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. (PubMed id 21079607)1 Wang K....Hakonarson H. (Mol. Psychiatry 2011)
    7. WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. (PubMed id 21531708)1 Gan Q....Owens G.K. (J. Biol. Chem. 2011)
    8. Comparative proteomic analysis identifies a role for SUMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (Sci Signal 2011)
    9. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    10. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (Science 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57325 HGNC: 15904 AceView: CSRP2BP Ensembl:ENSG00000149474 euGenes: HUgn57325
    ECgene: CSRP2BP H-InvDB: CSRP2BP

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CSRP2BP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CSRP2BP gene:
    Search GeneIP for patents involving CSRP2BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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