Aliases for CSRP2 Gene
External Ids for CSRP2 Gene
Previous GeneCards Identifiers for CSRP2 Gene
CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for CSRP2 Gene
CSRP2 (Cysteine And Glycine Rich Protein 2) is a Protein Coding gene. Diseases associated with CSRP2 include Miller-Dieker Lissencephaly Syndrome. Among its related pathways are Immune response IL-23 signaling pathway and ATF-2 transcription factor network. An important paralog of this gene is CSRP1.
UniProtKB/Swiss-Prot for CSRP2 Gene
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.