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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CSRP1 Gene

protein-coding   GIFtS: 57
GCID: GC01M201452

cysteine and glycine-rich protein 1


(Previous symbol: CYRP)
 Explore 14 diseases affiliated with
CSRP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CSRP1    

Aliases
for CSRP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cysteine And Glycine-Rich Protein 11 2     Cysteine-Rich Protein 12 3
CSRP1 2 3 5     CRP2 3
CYRP1 2 3     CRP12 3
D1S181E1 2     LIM-Domain Protein2

External Ids:    HGNC: 24691   Entrez Gene: 14652   Ensembl: ENSG000001591767   OMIM: 1238765   UniProtKB: P212913   

Export aliases for CSRP1 gene to outside databases

Previous GC identifers: GC01M199155 GC01M196889 GC01M197919 GC01M198740 GC01M198184 GC01M199719 GC01M172618


Summaries
for CSRP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CSRP1:
This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain
proteins, which may be involved in regulatory processes important for development and cellular differentiation. The
LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation,
cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. (provided by
RefSeq, Aug 2010)

UniProtKB/Swiss-Prot: CSRP1_HUMAN, P21291
Function: Could play a role in neuronal development

Gene Wiki entry for CSRP1


Genomic Views
for CSRP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CSRP1 gene promoter:
         USF1   GATA-3   USF2   Olf-1   USF-1:USF-2   AP-4   C/EBPalpha   CHOP-10   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CSRP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CSRP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSRP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32

CSRP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSRP1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M201452:  view genomic region     (about GC identifiers)

Start:
 201,452,658 bp from pter      End:
 201,478,584 bp from pter
Size:
 25,927 bases      Orientation:
 minus strand

Proteins
for CSRP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CSRP1_HUMAN, P21291 (See protein sequence)
Recommended Name: Cysteine and glycine-rich protein 1  
Size: 193 amino acids; 20567 Da
Subunit: Monomer (By similarity)
Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for CSRP1: NX_P21291

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P21291

    • CSRP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001180499.1  NP_001180500.1  NP_001180501.1  NP_004069.1  

    ENSEMBL proteins: 
     ENSP00000356275   ENSP00000432110   ENSP00000434147   ENSP00000436792   ENSP00000436491  
     ENSP00000437218   ENSP00000345079  

    Human Recombinant Protein Products: 
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    Novus Biologicals CSRP1 Proteins
    Novus Biologicals CSRP1 Lysate
    Sino Biological Recombinant Protein for CSRP1
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CSRP1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    CSRP1 for ontologies           About GeneDecksing



    CSRP1 Antibody Products: 
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    Uscn Antibodies for CSRP1
    ThermoFisher Antibodies for CSRP1

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    Uscn ELISAs and CLIAs for CSRP1

    Protein Domains /
    Families
    for CSRP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CSRP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry P21291

    ProtoNet protein and cluster: P21291

    1 Blocks protein family: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: CSRP1_HUMAN, P21291
    Similarity: Contains 2 LIM zinc-binding domains


    Function
    for CSRP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CSRP1_HUMAN, P21291
    Function: Could play a role in neuronal development

         Genatlas biochemistry entry for CSRP1:
    cysteine and glycine rich protein,20.5kDa,expressed by a serum-inducible immediate response gene,likely involved in the
    determination of cell lineage and regulation of cell differentiation

    miRNA
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    hsa-mir-1 (MIRT001373)

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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSRP1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate CSRP1:
    hsa-miR-3934 hsa-miR-3606 hsa-miR-1245 hsa-miR-188-3p hsa-miR-921 hsa-miR-1207-5p hsa-miR-4308 hsa-miR-34a*
    SwitchGear 3'UTR luciferase reporter plasmid: CSRP1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSRP1 (see all 7)
    OriGene shRNA RFP: CSRP1
    OriGene siRNA: CSRP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSRP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CSRP1

    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 4): CSRP1 (NM_001193570)
    Sino Biological Human cDNA Clone for CSRP1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRP1 

    Cell Line
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    Search LifeMap BioReagents cell lines for CSRP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRP1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--


    CSRP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CSRP1:
     Decreased focal adhesion (FA)  

    Animal Models:
         Mouse knock-out Csrp1tm1Mbk for CSRP1
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Csrp1):
     cardiovascular system  homeostasis/metabolism  muscle 

    CSRP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CSRP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CSRP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/7 Interacting proteins for CSRP1 (P212913 ENSP000003450794) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTN1P128143, ENSP000003779414I2D: score=2 STRING: ENSP00000377941
    EGFRP005333, ENSP000002754934I2D: score=2 STRING: ENSP00000275493
    YWHAZP631043I2D: score=1 
    CRPENSP000002550304STRING: ENSP00000255030
    GRB2ENSP000003390074STRING: ENSP00000339007
    About this table

    Drugs & Compounds
    for CSRP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CSRP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CSRP1
    2 Novoseek chemical compound relationships for CSRP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cysteine 51.7 12 8286377 (1), 12667067 (1), 10191274 (1), 7664053 (1) (see all 8)
    zinc 48.6 6 9115265 (2), 8632452 (1), 8841116 (1), 17934856 (1)

    Search CenterWatch for drugs/clinical trials and news about CSRP1 

    Transcripts
    for CSRP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CSRP1 gene (5 alternative transcripts): 
    NM_001193570.1  NM_001193571.1  NM_001193572.1  NM_004078.2  NM_001144773.1  

    Unigene Cluster for CSRP1:

    Cysteine and glycine-rich protein 1
    Hs.108080  [show with all ESTs]
    Unigene Representative Sequence: CR627407
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000367306(uc021phg.1 uc021phh.1 uc001gws.3 uc010ppr.2)
    ENST00000533402 ENST00000527662(uc001gwr.2) ENST00000532313 ENST00000531916
    ENST00000532460 ENST00000526256 ENST00000533432 ENST00000530120 ENST00000526723
    ENST00000526317 ENST00000524951 ENST00000458271(uc010pps.2) ENST00000527573
    ENST00000529975 ENST00000533188 ENST00000471596 ENST00000481851

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSRP1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate CSRP1:
    hsa-miR-3934 hsa-miR-3606 hsa-miR-1245 hsa-miR-188-3p hsa-miR-921 hsa-miR-1207-5p hsa-miR-4308 hsa-miR-34a*
    SwitchGear 3'UTR luciferase reporter plasmid: CSRP1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSRP1 (see all 7)
    OriGene shRNA RFP: CSRP1
    OriGene siRNA: CSRP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSRP1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSRP1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 4): CSRP1 (NM_001193570)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSRP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRP1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSRP1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CSRP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSRP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSRP1

    Additional cDNA sequence: 

    AB209756.1 AK057876.1 AK122812.1 AK126445.1 AK126507.1 AK290133.1 AK293053.1 AK302237.1 
    AK304415.1 BC004265.1 BC007492.2 BC018806.1 BC032493.1 BT019520.1 BX537488.1 BX641046.1 
    CR627407.1 M33146.1 

    24/36 DOTS entries (see all 36):

    DT.95107072  DT.100879890  DT.40189536  DT.100879897  DT.91717746  DT.100646778  DT.97836273  DT.95249407 
    DT.101985493  DT.100879896  DT.101985492  DT.100879879  DT.95087014  DT.100879888  DT.100032992  DT.95217240 
    DT.121461440  DT.121461475  DT.100879887  DT.100879889  DT.92468624  DT.97858197  DT.100759569  DT.100835566 

    24/967 AceView cDNA sequences (see all 967):

    BQ686886 CA407928 BX505038 BP372485 CB117611 CF132210 BP368013 BU507499 
    BP372651 BC004265 BQ959569 CR598103 BP342009 BP374704 CA389822 BP342020 
    BM839641 NM_004078 BP372481 AU138649 CR615597 BP380005 CR610287 AA046054 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for CSRP1 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e · 5f ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d · 8e ·
    SP1:                          -                                                                       -     -     -     -                                       
    SP2:                          -                                                                 -     -     -     -     -                                       
    SP3:                          -     -                                                                 -     -     -     -                                       
    SP4:                          -                                         -     -                       -     -     -     -                                       
    SP5:                          -                       -     -                                         -     -     -     -                                       

    ExUns: 8f ^ 9a · 9b
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for CSRP1

    Expression
    for CSRP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CSRP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCTGTACCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CSRP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/13 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 13) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeHindgutHindgut Endoderm CellsEndoderm
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    LimbZeugopodPrechondrocytic Mesenchymal CellsBone, Cartilage
    Reproductive SystemMesonephrosMesonephric cellsReproductive System
    Gut TubeHindgutGut Tube
    Gut TubeMidgutGut Tube
    HeartHeart TubeHeart
    KidneyGlomerular TuftKidney
    KidneyGlomerulusKidney
    KidneyInterstitial StromaKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 7 LifeMap Cells 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ progenitor E68 (Embryonic Progenitor Cell)
    PureStem™ progenitor T42 (Embryonic Progenitor Cell)
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)

    See CSRP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CSRP1

    SOURCE GeneReport for Unigene cluster: Hs.108080
        SABiosciences Custom PCR Arrays for CSRP1
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    In Situ
    Assay Products:     
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    Orthologs
    for CSRP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CSRP1 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CSRP11 cysteine and glycine-rich protein 1 81.9(n)
    90.32(a)    		   396176  NM_205248.1  NP_990579.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CSRP16
    		 --
    		 89(a)
    		 1 ↔ 1
    		 4(131544466-131553943)
    zebrafish
    (Danio rerio)    		 Actinopterygii csrp12 cysteine and glycine-rich protein 1 75.67(n)   378726  CK026064.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Mlp84B1 , 3 cell differentiation3
    Muscle LIM protein at 84B1    		 48(a)3
    56.51(n)1
    53.45(a)1    		   408491  NM_057774.41  NP_477122.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea mlp-11 Protein MLP-1 52.14(n)
    47.86(a)    		   175847  NM_065900.2  NP_498301.2 


    ENSEMBL Gene Tree for CSRP1 (if available)
    TreeFam Gene Tree for CSRP1 (if available) 

    Paralogs
    for CSRP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CSRP1 gene
    CSRP22  CRIP22  ENSG000002573412  CRIP32  CRIP12  CSRP32  
    11 SIMAP similar genes for CSRP1 using alignment to 5 protein entries:     CSRP1_HUMAN (see all proteins):
    DKFZp686M148    DKFZp686P2249    CSRP3    CSRP2    AJUBA    CRIP1
    LHX6    LHX8    CRIP3    CRIP2    LIMS2

    CSRP1 for paralogs           About GeneDecksing



    Genomic Variants
    for CSRP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/497 NCBI SNPs in CSRP1 are shown (see all 497)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs5865071,2
    		C,F,A,H,--201452356(-) ACAAAC/TGTGAA 4 -- ds500115Minor allele frequency- T:0.15NA WA CSA EA 381
    rs4948381,2
    		C,F,A,H,--201452473(-) GGTGGT/CGGGTG 4 -- ds500112Minor allele frequency- C:0.31MN NA WA CSA 572
    rs10536351,2
    		C,H--201452906(-) AGAATC/TTTCCC 4 -- ut31 trp37Minor allele frequency- T:0.02MN NS EA NA 604
    rs562427491,2
    		C,--201453022(+) CTGGGC/ATCTGC 4 -- ut312Minor allele frequency- A:0.09WA 120
    rs1867361591,2
    		--201453063(+) CCAGAC/GATAAA 4 -- ut310--------
    rs1911787491,2
    		--201453079(+) ATTTGA/GGCCAT 4 -- ut310--------
    rs5766971,2
    		C,F,A,H,--201453289(+) GACCCC/G/TGCCTG 8 -- ut31 ese321EA NA WA CSA 1987
    rs1382570591,2
    		--201453314(+) TCCAAC/TAGTGA 4 -- ut310--------
    rs1412146021,2
    		--201453407(+) ATCCAA/GAAAAC 4 -- ut310--------
    rs778904101,2
    		C,--201453417(+) CCCAGC/TCTTCC 4 -- ut310--------

    HapMap Linkage Disequilibrium report for CSRP1 (201452658 - 201478584 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CSRP1: --

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    Disorders / Diseases
    for CSRP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CSRP1 for disorders           About GeneDecksing

    OMIM gene information: 123876    OMIM disorders: --

    14 diseases for CSRP1:    About MalaCards
    endocardial fibroelastosis    pontiac fever    dilated cardiomyopathy    herpes simplex
    diphtheria    crohn's disease    cardiomyopathy    sepsis
    hepatocellular carcinoma    lung cancer    prostate cancer    prostatitis
    carcinoma    neuronitis

    2 Novoseek disease relationships for CSRP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sepsis 7.75 4 10208949 (1), 17691022 (1), 10452048 (1)
    tumors 4.94 1 11119586 (1)

    Human Genome Epidemiology (HuGE) Navigator: CSRP1 (1 document)

    Export disorders for CSRP1 gene to outside databases

    Publications
    for CSRP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CSRP1 gene, integrated from 9 sources (see all 78):
    (articles sorted by number of sources associating them with CSRP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif. (PubMed id 2115670)1, 2, 3 Liebhaber S.A.... Cooke N.E. (1990)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization. (PubMed id 9925910)1, 3 Erdel M. and Weiskirchen R. (1998)
    6. Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc. (PubMed id 1374386)1, 2 Wang X.... Cooke N.E. (1992)
    7. Ultraviolet B radiation regulates cysteine-rich prote in 1 in human keratinocytes. (PubMed id 20415737)1, 9 Latonen L....Laiho M. (2010)
    8. Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma. (PubMed id 17341888)1, 9 Hirasawa Y....Yokosuka O. (2006)
    9. Fine mapping of the alpha-actinin binding site within cysteine-rich protein. (PubMed id 10926853)1, 9 Harper B.D....Pomies P. (2000)
    10. Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism. (PubMed id 1385304)1, 9 Wang X....Cooke N.E. (1992)

    External Searches for CSRP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing CSRP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1465 HGNC: 2469 AceView: CSRP1 Ensembl:ENSG00000159176 euGenes: HUgn1465
    ECgene: CSRP1 H-InvDB: CSRP1

    Other Databases showing CSRP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CSRP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CSRP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CSRP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CSRP1 gene:
    Search GeneIP for patents involving CSRP1

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