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CSRNP2 Gene

protein-coding   GIFtS: 47
GCID: GC12M051454

Cysteine-Serine-Rich Nuclear Protein 2

(Previous names: chromosome 12 open reading frame 22, family with sequence...)
(Previous symbols: C12orf22, FAM130A1)
  Search for CSRNP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cysteine-Serine-Rich Nuclear Protein 21 2     Protein Phosphatase 11
C12orf221 2 3     Regulatory Subunit 721
FAM130A11 2 3     C12orf22
Family With Sequence Similarity 130, Member A11 2     PPP1R722
CSRNP-22 3     Cysteine/Serine-Rich Nuclear Protein 22
TAIP-122 3     Protein Phosphatase 1, Regulatory Subunit 722
TGF-Beta-Induced Apoptosis Protein 122 3     TAIP123
Chromosome 12 Open Reading Frame 221     Protein FAM130A13

External Ids:    HGNC: 160061   Entrez Gene: 815662   Ensembl: ENSG000001109257   UniProtKB: Q9H1753   

Export aliases for CSRNP2 gene to outside databases

Previous GC identifers: GC12M049743 GC12M048487


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CSRNP2 Gene:
The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions,
including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the
sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may
have redundant functions. Alternatively spliced transcript variants have been found for this gene. (provided by
RefSeq, Aug 2011)

GeneCards Summary for CSRNP2 Gene:
CSRNP2 (cysteine-serine-rich nuclear protein 2) is a protein-coding gene. GO annotations related to this gene include phosphatase binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is CSRNP1.

UniProtKB/Swiss-Prot: CSRN2_HUMAN, Q9H175
Function: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity).
May play a role in apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CSRNP2 gene promoter:
         HOXA9B   HOXA9   AML1a   MEF-2   Cdc5   C/EBPalpha   MEF-2A   IRF-7A   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSRNP2 promoter sequence
   Search Chromatin IP Primers for CSRNP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSRNP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.11-q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.11-q13.12

CSRNP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSRNP2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051454:  view genomic region     (about GC identifiers)

Start:
51,454,990 bp from pter      End:
51,477,447 bp from pter
Size:
22,458 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CSRN2_HUMAN, Q9H175 (See protein sequence)
Recommended Name: Cysteine/serine-rich nuclear protein 2  
Size: 543 amino acids; 59591 Da

Explore the universe of human proteins at neXtProt for CSRNP2: NX_Q9H175

Explore proteomics data for CSRNP2 at MOPED


See CSRNP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_110436.1  
ENSEMBL proteins: 
 ENSP00000228515   ENSP00000447983   ENSP00000447657   ENSP00000447065   ENSP00000449152  

CSRNP2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
PPP1R: Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits

1 InterPro protein domain:
 IPR023260 Cys/Ser-rich_nuc_prot

Graphical View of Domain Structure for InterPro Entry Q9H175

ProtoNet protein and cluster: Q9H175

UniProtKB/Swiss-Prot: CSRN2_HUMAN, Q9H175
Similarity: Belongs to the AXUD1 family


Find genes that share domains with CSRNP2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CSRN2_HUMAN, Q9H175
Function: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity).
May play a role in apoptosis

     Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity ISS17726538
GO:0005515protein binding IPI15231748
GO:0019902phosphatase binding IDA19389623
     
Find genes that share ontologies with CSRNP2           About GenesLikeMe


Phenotypes:
     4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Csrnp2):
 embryogenesis  hematopoietic system  immune system  mortality/aging 

Find genes that share phenotypes with CSRNP2           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Csrnp2tm1Jni for CSRNP2

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CSRNP2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CSRNP2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CSRNP2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CSRNP2

miRNA
Products:
    
miRTarBase miRNAs that target CSRNP2:
hsa-mir-125b-5p (MIRT046040)

Block miRNA regulation of human, mouse, rat CSRNP2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate CSRNP2 (see all 85):
hsa-miR-3130-5p hsa-miR-15a hsa-miR-1260b hsa-miR-3148 hsa-miR-374b* hsa-miR-4300 hsa-miR-130a* hsa-miR-23c
SwitchGear 3'UTR luciferase reporter plasmidCSRNP2 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for CSRNP2
Predesigned siRNA for gene silencing in human, mouse, rat CSRNP2

Gene Editing
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GenScript: all cDNA clones in your preferred vector: CSRNP2 (NM_030809)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRNP2

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRNP2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CSRN2_HUMAN, Q9H175: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
chloroplast2
cytosol2

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus ISS17726538

Find genes that share ontologies with CSRNP2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CSRNP2
Interactions:

    Search GeneGlobe Interaction Network for CSRNP2

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CSRNP2 (Q9H1751, 2, 3 ENSP000002285154) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
PPP1CAP621361, 2, 3, ENSP000003260314EBI-5235958,EBI-357253 MINT-62208 I2D: score=3 STRING: ENSP00000326031
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated ----
GO:0006915apoptotic process IEA--
GO:0010923negative regulation of phosphatase activity IDA19389623
GO:0045944positive regulation of transcription from RNA polymerase II promoter ISS17726538

Find genes that share ontologies with CSRNP2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CSRNP2 (CSRN2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CSRNP2 gene: 
NM_030809.2  

Unigene Cluster for CSRNP2:

Cysteine-serine-rich nuclear protein 2
Hs.524425  [show with all ESTs]
Unigene Representative Sequence: NR_045072
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000228515(uc021qxx.1 uc001rxu.2) ENST00000548206 ENST00000548981
ENST00000550533 ENST00000552899 ENST00000546935 ENST00000552680 ENST00000550461

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CSRNP2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate CSRNP2 (see all 85):
hsa-miR-3130-5p hsa-miR-15a hsa-miR-1260b hsa-miR-3148 hsa-miR-374b* hsa-miR-4300 hsa-miR-130a* hsa-miR-23c
SwitchGear 3'UTR luciferase reporter plasmidCSRNP2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CSRNP2
Predesigned siRNA for gene silencing in human, mouse, rat CSRNP2
Clone
Products:
     
OriGene clones in human, mouse for CSRNP2 (see all 7)
OriGene ORF clones in mouse, rat for CSRNP2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CSRNP2 (NM_030809)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSRNP2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSRNP2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CSRNP2
OriGene qSTAR qPCR primer pairs in human, mouse for CSRNP2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CSRNP2
  QuantiTect SYBR Green Assays in human, mouse, rat CSRNP2
  QuantiFast Probe-based Assays in human, mouse, rat CSRNP2

Additional mRNA sequence: 

AB063302.2 AF052105.1 AJ298133.1 AK098442.1 AK313080.1 BC017221.2 NR_045072.1 

8 DOTS entries:

DT.455833  DT.92425990  DT.100786615  DT.95169678  DT.100025243  DT.100659376  DT.100786616  DT.40273734 

Selected AceView cDNA sequences (see all 203):

AI990241 AI027258 AW449343 AA393444 AA814410 AI377549 BQ023792 CA390415 
AW008687 BE704201 Z38350 AA718981 AI910380 CA311793 F11720 AF052105 
BM142231 AA425674 BM840014 AI081621 AA703699 AI085023 BE779647 BU736512 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for CSRNP2 (see all 8)    About this scheme

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b ^ 8
SP1:                                -     -     -     -     -     -                                                         
SP2:        -     -     -     -     -     -     -     -     -     -                                                         
SP3:                                -     -                                                                                 
SP4:                                      -     -     -     -     -     -                                                   
SP5:                                      -     -     -     -     -                                                         


ECgene alternative splicing isoforms for CSRNP2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CSRNP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GTTGCTAGGA
CSRNP2 Expression
About this image

CSRNP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CSRNP2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.524425
    Custom PCR Arrays for CSRNP2
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSRNP2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for CSRNP2 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Csrnp21 , 5 cysteine-serine-rich nuclear protein 21, 5 86.45(n)1
92.32(a)1
  15 (56.32 cM)5
2077851  NM_153407.21  NP_700456.11 
 1004795705 
chicken
(Gallus gallus)
Aves CSRNP21 cysteine-serine-rich nuclear protein 2 75.82(n)
82.11(a)
  100859835  XM_003643886.2  XP_003643934.2 
lizard
(Anolis carolinensis)
Reptilia CSRNP26
cysteine-serine-rich nuclear protein 2
71(a)
1 ↔ 1
2(67412580-67450538)
tropical clawed frog
(Xenopus tropicalis)
Amphibia csrnp21 cysteine-serine-rich nuclear protein 2 66.67(n)
70.66(a)
  100145289  NM_001126767.1  NP_001120239.1 
zebrafish
(Danio rerio)
Actinopterygii csrnp21 cysteine-serine-rich nuclear protein 2 62.86(n)
62.38(a)
  100003989  XM_001343376.5  XP_001343412.1 
fruit fly
(Drosophila melanogaster)
Insecta Axud16
--
18(a)
1 → many
2L(2365345-2370137)
worm
(Caenorhabditis elegans)
Secernentea C41D11.36
Protein C41D11.3, isoform a (C41D11.3) mRNA, compl...
20(a)
1 → many
I(4428475-4431916) WBGene00016562


ENSEMBL Gene Tree for CSRNP2 (if available)
TreeFam Gene Tree for CSRNP2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CSRNP2 gene
CSRNP12  CSRNP32  
2 SIMAP similar genes for CSRNP2 using alignment to 5 protein entries:     CSRN2_HUMAN (see all proteins):
CSRNP3    CSRNP1

Find genes that share paralogs with CSRNP2           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CSRNP2 (see all 581)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs111696901,2
C,F,H--51454786(+) TCAGCC/TGAACA 2 -- ds500134Minor allele frequency- N:0.00NS EA NA WA CSA 3260
rs1910167271,2
--51454816(+) ACCAAA/GTCCAG 2 -- ds50010--------
rs1409220021,2
--51454838(+) CCAAAA/GAGAAT 2 -- ds50010--------
rs1810376531,2
--51454935(+) ATCCTC/TTTTCT 2 -- ds50010--------
rs111696911,2
C,F,H--51454952(+) TAACTG/CAACTG 2 -- ds500113Minor allele frequency- C:0.36NA NS EA WA 926
rs1863923231,2
C--51455013(+) ATATTA/CCATTT 2 -- ut31 nc-transcript-variant0--------
rs73097891,2
C,F,H--51455075(+) AAAAAA/GTTATT 2 -- ut31 nc-transcript-varianttrp311Minor allele frequency- G:0.20NS EA NA WA CSA 784
rs1911516661,2
--51455119(+) GAAAAC/TACTAC 2 -- ut31 nc-transcript-variant0--------
rs77221,2
C,F,A,H--51455404(-) TTAACG/TCTACA 2 -- ut31 nc-transcript-variantese323Minor allele frequency- T:0.44MN NA NS EA WA CSA 2661
rs1497673081,2
--51455571(+) GCCGGA/CGCCTT 2 -- ut31 nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for CSRNP2 (51454990 - 51477447 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CSRNP2:    About this table    
Variant IDTypeSubtypePubMed ID
esv2671499CNV Deletion23128226
esv34039CNV Loss18971310

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CSRNP2
DNA2.0 Custom Variant and Variant Library Synthesis for CSRNP2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Find genes that share disorders with CSRNP2           About GenesLikeMe

Genetic Association Database (GAD): CSRNP2
Human Genome Epidemiology (HuGE) Navigator: CSRNP2 (1 document)

Export disorders for CSRNP2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CSRNP2 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with CSRNP2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. (PubMed id 20800603)1, 4 Flachsbart F....Nebel A. (Mutat. Res. 2010)
  2. Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP). (PubMed id 17726538)1, 3 Gingras S....Ihle J.N. (PLoS ONE 2007)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  5. Docking motif-guided mapping of the interactome of protein phosphatase-1. (PubMed id 19389623)1 Hendrickx A.... Bollen M. (Chem. Biol. 2009)
  6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  7. Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (Genome Res. 2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (Genome Res. 1997)
  10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 81566 HGNC: 16006 AceView: C12orf22 Ensembl:ENSG00000110925 euGenes: HUgn81566
ECgene: CSRNP2 H-InvDB: CSRNP2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CSRNP2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CSRNP2 gene:
Search GeneIP for patents involving CSRNP2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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