Aliases for CSRNP1 Gene
External Ids for CSRNP1 Gene
Previous HGNC Symbols for CSRNP1 Gene
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for CSRNP1 Gene
CSRNP1 (Cysteine And Serine Rich Nuclear Protein 1) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. An important paralog of this gene is CSRNP2.
UniProtKB/Swiss-Prot for CSRNP1 Gene
Binds to the consensus sequence 5-AGAGTG-3 and has transcriptional activator activity (By similarity). May have a tumor-suppressor function. May play a role in apoptosis.