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CSPP1 Gene

protein-coding   GIFtS: 50
GCID: GC08P067976

Centrosome And Spindle Pole Associated Protein 1

  See CSPP1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centrosome And Spindle Pole Associated Protein 11 2
CSPP2 3 5
JBTS212 5
Centrosome And Spindle Pole-Associated Protein 12

External Ids:    HGNC: 261931   Entrez Gene: 798482   Ensembl: ENSG000001042187   OMIM: 6116545   UniProtKB: Q1MSJ53   

Export aliases for CSPP1 gene to outside databases

Previous GC identifers: GC08P068141 GC08P063469


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CSPP1 Gene:
This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle
progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for
cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome.
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. (provided by
RefSeq, Apr 2014)

GeneCards Summary for CSPP1 Gene:
CSPP1 (centrosome and spindle pole associated protein 1) is a protein-coding gene. Diseases associated with CSPP1 include joubert syndrome 21, and joubert syndrome with jeune asphyxiating thoracic dystrophy.

UniProtKB/Swiss-Prot: CSPP1_HUMAN, Q1MSJ5
Function: May play a role in cell-cycle-dependent microtubule organization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_008183.20  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CSPP1 gene promoter:
         HFH-3   Pax-2   Pax-2a   FOXI1   MEF-2A   Pax-2b   NRF-2   POU2F1   POU2F1a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSPP1 promoter sequence
   Search Chromatin IP Primers for CSPP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSPP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.2   Ensembl cytogenetic band:  8q13.1   HGNC cytogenetic band: 8q13.2

CSPP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSPP1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P067976:  view genomic region     (about GC identifiers)

Start:
67,974,661 bp from pter      End:
68,108,849 bp from pter
Size:
134,189 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CSPP1_HUMAN, Q1MSJ5 (See protein sequence)
Recommended Name: Centrosome and spindle pole-associated protein 1  
Size: 1256 amino acids; 145522 Da
Subunit: Interacts with PLEKHG6 (By similarity)
Developmental stage: Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase. Isoform 2
expression is highest in G1 phase and decreases thereafter
Sequence caution: Sequence=AAH22867.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6ND63 Q70F00 Q8TBC1
Alternative splicing: 3 isoforms:  Q1MSJ5-3   Q1MSJ5-1   Q1MSJ5-2   

Explore the universe of human proteins at neXtProt for CSPP1: NX_Q1MSJ5

Explore proteomics data for CSPP1 at MOPED

Post-translational modifications: 

  • Phosphorylated. Phosphorylation increases in colcemide-treated cells1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CSPP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001278268.1  NP_079066.5  

    ENSEMBL proteins: 
     ENSP00000429546   ENSP00000262210   ENSP00000428793   ENSP00000428694   ENSP00000430092  
     ENSP00000415782  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026708 CSPP1

    Graphical View of Domain Structure for InterPro Entry Q1MSJ5

    ProtoNet protein and cluster: Q1MSJ5


    Find genes that share domains with CSPP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CSPP1_HUMAN, Q1MSJ5
    Function: May play a role in cell-cycle-dependent microtubule organization

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CSPP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CSPP1:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CSPP1
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    Block miRNA regulation of human, mouse, rat CSPP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CSPP1 (see all 14):
    hsa-miR-205 hsa-miR-944 hsa-miR-3617 hsa-miR-3924 hsa-miR-4282 hsa-miR-1284 hsa-miR-124 hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidCSPP1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CSPP1_HUMAN, Q1MSJ5: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton,
    spindle. Cytoplasm, cytoskeleton, spindle pole (By similarity). Note=Associated with mitotic spindles
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol1
    extracellular1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000922spindle pole IDA19129481
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IDA19129481
    GO:0005874microtubule IEA--

    Find genes that share ontologies with CSPP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CSPP1
    Interactions:

        GeneGlobe Interaction Network for CSPP1

    1 Interacting protein for CSPP1 (Q1MSJ53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032467positive regulation of cytokinesis IMP19129481
    GO:0051781positive regulation of cell division IMP19129481

    Find genes that share ontologies with CSPP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CSPP1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CSPP1 gene (3 alternative transcripts): 
    NM_001291339.1  NM_001077204.1  NM_024790.6  

    Unigene Cluster for CSPP1:

    Centrosome and spindle pole associated protein 1
    Hs.370147  [show with all ESTs]
    Unigene Representative Sequence: NM_024790
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521919 ENST00000262210(uc003xxj.3 uc003xxi.3 uc003xxk.3 uc010lyw.3)
    ENST00000519701 ENST00000519163(uc003xxg.1 uc003xxh.1) ENST00000519668
    ENST00000521168 ENST00000521324 ENST00000412460
    miRNA
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    Block miRNA regulation of human, mouse, rat CSPP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CSPP1 (see all 14):
    hsa-miR-205 hsa-miR-944 hsa-miR-3617 hsa-miR-3924 hsa-miR-4282 hsa-miR-1284 hsa-miR-124 hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidCSPP1 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSPP1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CSPP1
      QuantiTect SYBR Green Assays in human, mouse, rat CSPP1
      QuantiFast Probe-based Assays in human, mouse, rat CSPP1

    Additional mRNA sequence: 

    AJ583433.1 AK096205.1 AK127108.1 AK308372.1 AM156947.1 BC022867.1 BC029445.1 BX649147.1 

    18 DOTS entries:

    DT.443891  DT.97840977  DT.100023962  DT.91721224  DT.40213904  DT.99964206  DT.100673897  DT.100670730 
    DT.99944378  DT.100044163  DT.103289  DT.75173739  DT.87004357  DT.120640439  DT.120640566  DT.120640598 
    DT.120640610  DT.70104798 

    Selected AceView cDNA sequences (see all 103):

    BX649147 BM767347 AI125328 BQ012105 AW451189 AI474550 AW291113 H54754 
    AA721639 AI400587 AA883157 AL042666 BM771016 CA447290 AI621096 BM914827 
    CB243947 AK096205 BF223888 BM770928 BE673399 AA759354 BM744376 CB118683 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CSPP1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^
    SP1:                          -                                                                                                                                 
    SP2:                          -                 -                                                                                                               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                    -               
    SP5:                                    


    ECgene alternative splicing isoforms for CSPP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CSPP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGTAACTAC
    CSPP1 Expression
    About this image

    CSPP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CSPP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370147

    UniProtKB/Swiss-Prot: CSPP1_HUMAN, Q1MSJ5
    Tissue specificity: Detected in testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSPP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CSPP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cspp11 , 5 centrosome and spindle pole associated protein 11, 5 83.42(n)1
    79.21(a)1
      1 (2.30 cM)5
    2116601  NM_026493.31  NP_080769.31 
     100382185 
    chicken
    (Gallus gallus)
    Aves CSPP11 centrosome and spindle pole associated protein 1 67.93(n)
    59.76(a)
      420169  XM_004939898.1  XP_004939955.1 
    lizard
    (Anolis carolinensis)
    Reptilia CSPP16
    centrosome and spindle pole associated protein 1
    53(a)
    1 ↔ 1
    4(31114035-31171649)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.43862 Xenopus laevis transcribed sequence with weak similarity to protein pirT46481 (H.sapiens) T46481 hypothetical protein DKFZp434A025.1 - human (fragment) less 75.2(n)    CA787974.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-97a13.91 si:dkey-97a13.9 55.33(n)
    47.17(a)
      570598  XM_694098.5  XP_699190.4 


    ENSEMBL Gene Tree for CSPP1 (if available)
    TreeFam Gene Tree for CSPP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CSPP1 gene
    16 SIMAP similar genes for CSPP1 using alignment to 4 protein entries:     CSPP1_HUMAN (see all proteins):
    IK    CALCOCO2    C14orf105    RHBG    SLC24A1    DPP9
    FRG1    RBP7    LSM12    MRPL45    EEF1E1    GALK2
    TUBA1C    C12orf76    ZNF554    EIF3K

    Find genes that share paralogs with CSPP1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CSPP1 (see all 2224)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs617353151,2
    C,F--67976577(+) GTTGGC/TGAAGG 1 -- us2k12Minor allele frequency- T:0.02NS NA 196
    rs1814708461,2
    C,F--67976663(+) GCTGTA/GACCTC 2 V syn11Minor allele frequency- G:0.01EU 1267
    rs2002507311,2
    --67976683(+) CGACGA/GTCCTC 2 D G mis10--------
    rs1172107471,2
    C,F--67976750(+) AGCCGC/GGGATG 1 -- int11Minor allele frequency- G:0.04NA 120
    rs1143503751,2
    C,F--67976754(+) GCGGAT/AGGGGA 1 -- int11Minor allele frequency- A:0.25WA 118
    rs132738661,2
    F--67976792(+) TGGTGT/CAGGTT 1 -- int12Minor allele frequency- C:0.25NA 4
    rs1862062621,2
    --67976918(+) CTCTGC/GAATCT 1 -- int10--------
    rs1400606051,2
    C--67976935(+) GGGGT-/GGGGGT 1 -- int10--------
    rs761815001,2
    C--67977009(+) GTGGAG/TAGTTG 1 -- int13Minor allele frequency- T:0.22NA EA 242
    rs1147906911,2
    F--67977158(+) CGGTCG/TCTGCT 1 -- int11Minor allele frequency- T:0.04WA 118

    HapMap Linkage Disequilibrium report for CSPP1 (67974661 - 68108849 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CSPP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2737120CNV Deletion23290073
    esv2675478CNV Deletion23128226
    esv2197789CNV Deletion18987734
    nsv438063CNV Loss16468122
    nsv890975CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611654   
    OMIM disorders: 615636  
    3 diseases for CSPP1:    
    About MalaCards
    joubert syndrome 21    joubert syndrome with jeune asphyxiating thoracic dystrophy    asphyxiating thoracic dystrophy


    Find genes that share disorders with CSPP1           About GenesLikeMe

    Genetic Association Database (GAD): CSPP1
    Human Genome Epidemiology (HuGE) Navigator: CSPP1 (1 document)

    Export disorders for CSPP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CSPP1 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with CSPP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel centrosome/microtubule-associated coiled- coil protein involved in cell-cycle progression and spindle organization. (PubMed id 15580290)1, 2, 3, 9 Patzke S.... Aasheim H.-C. (Oncogene 2005)
    2. CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization. (PubMed id 16826565)1, 2, 9 Patzke S.... Aasheim H.-C. (J. Cell. Physiol. 2006)
    3. Mutations in CSPP1 Lead to Classical Joubert Syndrome. (PubMed id 24360807)1, 3 Akizu N....Gleeson J.G. (Am. J. Hum. Genet. 2014)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle. (PubMed id 19129481)1, 9 Asiedu M.... Wei Q. (Mol. Biol. Cell 2009)
    6. Mutations in CSPP1 Cause Primary Cilia Abnormalities and Joubert Syndrome with or without Jeune Asphyxiating Thoracic Dystrophy. (PubMed id 24360808)1 Tuz K....Ferland R.J. (Am. J. Hum. Genet. 2014)
    7. Mutations in CSPP1, encoding a core centrosomal protein, cause a range of ciliopathy phenotypes in humans. (PubMed id 24360803)1 Shaheen R....Alkuraya F.S. (Am. J. Hum. Genet. 2014)
    8. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79848 HGNC: 26193 AceView: FLJ22490 Ensembl:ENSG00000104218 euGenes: HUgn79848
    ECgene: CSPP1 H-InvDB: CSPP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CSPP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CSPP1 gene:
    Search GeneIP for patents involving CSPP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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