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CSN3 Gene

protein-coding   GIFtS: 55
GCID: GC04P071156

Casein Kappa

(Previous names: casein, kappa)
(Previous symbol: CSN10)
  See CSN3-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Casein Kappa1 2     KCA2
CSN101 2 3 5     kappa-casein2
CSNK2 3     CASK3
Casein, Kappa1     

External Ids:    HGNC: 24461   Entrez Gene: 14482   Ensembl: ENSG000001712097   OMIM: 6016955   UniProtKB: P074983   

Export aliases for CSN3 gene to outside databases

Previous GC identifers: GC04P071358 GC04P071423 GC04P071289 GC04P066910


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CSN3 Gene:
CSN3 (casein kappa) is a protein-coding gene. Diseases associated with CSN3 include dentin sensitivity, and mammary paget's disease.

UniProtKB/Swiss-Prot: CASK_HUMAN, P07498
Function: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk

Gene Wiki entry for CSN3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the CSN3 gene promoter:
         TBP   AML1a   AP-1   ATF-2   HNF-3beta   RORalpha1   POU2F1   TFIID   POU2F1a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSN3 promoter sequence
   Search Chromatin IP Primers for CSN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21.1

CSN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSN3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P071156:  view genomic region     (about GC identifiers)

Start:
71,108,305 bp from pter      End:
71,117,145 bp from pter
Size:
8,841 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CASK_HUMAN, P07498 (See protein sequence)
Recommended Name: Kappa-casein precursor  
Size: 182 amino acids; 20305 Da
Subunit: Heteromultimers composed of alpha-s1 casein and kappa casein linked by disulfide bonds
Secondary accessions: Q13575

Explore the universe of human proteins at neXtProt for CSN3: NX_P07498

Post-translational modifications: 

  • The N-terminus is blocked1
  • Glycosylation2 at Thr133, Thr143, Thr148, Thr151, Thr157, Thr167, Thr169
  • Modification sites at PhosphoSitePlus
  • REFSEQ proteins: NP_005203.2  
    ENSEMBL proteins: 
     ENSP00000304822  

    CSN3 Human Recombinant Protein Products:

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    Novus Biologicals CSN3 Protein
    Novus Biologicals CSN3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CSN3

     
    Search eBioscience for Proteins for CSN3 

     
    antibodies-online proteins for CSN3 (18 products) 

     
    antibodies-online peptides for CSN3

    CSN3 Antibody Products:

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    antibodies-online antibodies for CSN3 (29 products) 

    CSN3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for CSN3
    Cloud-Clone Corp. CLIAs for CSN3
    Search eBioscience for ELISAs for CSN3 
    antibodies-online kits for CSN3 (19 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000117 Casein_kappa

    Graphical View of Domain Structure for InterPro Entry P07498

    ProtoNet protein and cluster: P07498

    1 Blocks protein domain: IPB000117 Kappa casein

    UniProtKB/Swiss-Prot: CASK_HUMAN, P07498
    Similarity: Belongs to the kappa-casein family


    Find genes that share domains with CSN3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CASK_HUMAN, P07498
    Function: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk

    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Csn3):

     endocrine/exocrine gland  integument 

    Find genes that share phenotypes with CSN3           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Csn3tm1Kuma for CSN3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CSN3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CSN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CSN3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CSN3

    miRNA
    Products:
        
    miRTarBase miRNAs that target CSN3:
    hsa-mir-335-5p (MIRT018995), hsa-mir-26b-5p (MIRT030202)

    Block miRNA regulation of human, mouse, rat CSN3 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CSN3:
    hsa-miR-3136-5p hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidCSN3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CSN3
    Predesigned siRNA for gene silencing in human, mouse, rat CSN3

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: CSN3 (NM_005212)
    Sino Biological Human cDNA Clone for CSN3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSN3

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CSN3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSN3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CASK_HUMAN, P07498: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    endoplasmic reticulum2
    plasma membrane2
    cytoskeleton1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with CSN3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for CSN3
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CSN3
    Interactions:

        Search GeneGlobe Interaction Network for CSN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for CSN3 (P074982, 3 ENSP000003048224) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2A2P197843, ENSP000002625064I2D: score=1 STRING: ENSP00000262506
    MAPRE1Q156913, ENSP000003647214I2D: score=1 STRING: ENSP00000364721
    CSN2P058143, ENSP000003410304I2D: score=1 STRING: ENSP00000341030
    COPS7AQ9UBW83, ENSP000002292514I2D: score=1 STRING: ENSP00000229251
    EIF3EP602283, ENSP000002208494I2D: score=1 STRING: ENSP00000220849
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007595lactation IEA--

    Find genes that share ontologies with CSN3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CSN3 (CASK)

    Selected Novoseek inferred chemical compound relationships for CSN3 gene (see all 19)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rennet 90.1 7 9839241 (1), 15747733 (1), 16674841 (1), 17658821 (1) (see all 6)
    whey 83.3 31 17658821 (3), 18701003 (2), 11358252 (2), 14705892 (2) (see all 19)
    glucono-delta-lactone 79.6 1 14664539 (1)
    sodium caseinate 71.9 6 19505156 (3)
    allergens 47.1 4 18307527 (1), 10594547 (1), 11529896 (1)
    peptone 36.5 1 12018413 (1)
    polyacrylamide 34.5 1 15545371 (1)
    lactose 33.4 2 15591397 (1)
    hydroxyapatite 31.8 3 10601790 (2), 7717888 (1)
    sodium dodecylsulfate 28 4 15545361 (1), 18155889 (1)



    Find genes that share compounds with CSN3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CSN3 gene: 
    NM_005212.2  

    Unigene Cluster for CSN3:

    Casein kappa
    Hs.54415  [show with all ESTs]
    Unigene Representative Sequence: BF667812
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000304954(uc003hfe.4)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CSN3 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CSN3:
    hsa-miR-3136-5p hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidCSN3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CSN3
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CSN3 (NM_005212)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CSN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSN3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CSN3
    OriGene qSTAR qPCR primer pairs in human, mouse for CSN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CSN3
      QuantiTect SYBR Green Assays in human, mouse, rat CSN3
      QuantiFast Probe-based Assays in human, mouse, rat CSN3

    Additional mRNA sequence: 

    BC010935.1 X66417.1 

    2 DOTS entries:

    DT.103940  DT.121249472 

    12 AceView cDNA sequences:

    BG199886 H25114 BC010935 NM_005212 BG204492 BG191674 BX283897 M73628 
    BG217189 X66417 BG210286 BF667812 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CSN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCACATTCAA
    CSN3 Expression
    About this image


    CSN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neurons
             Mature Rod Cells Outer Nuclear Layer
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer
     
     Skeletal Muscle (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
     
     Somite (Muscoskeletal System)
             Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
    CSN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.54415

    UniProtKB/Swiss-Prot: CASK_HUMAN, P07498
    Tissue specificity: Mammary gland specific. Secreted in milk

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CSN3 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Csn31 , 5 casein kappa1, 5 61.51(n)1
    37.5(a)1
      5 (43.56 cM)5
    129941  NM_007786.41  NP_031812.21 
     879255795 


    ENSEMBL Gene Tree for CSN3 (if available)
    TreeFam Gene Tree for CSN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CSN3 (see all 318)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs784354391,2
    C,F--71106347(+) AATTCA/GTCTAC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs738245601,2
    C,F--71106450(+) TATGAG/AGTCCA 1 -- us2k12Minor allele frequency- A:0.09WA 120
    rs1154725201,2
    F--71106468(+) AGAGAT/AGTTTA 1 -- us2k11Minor allele frequency- A:0.05NA 120
    rs623083701,2
    C--71106513(+) AAACAG/ATATCT 1 -- us2k14Minor allele frequency- A:0.21NA EA 244
    rs623083711,2
    C--71106516(+) CAGTAT/CCTGAA 1 -- us2k14Minor allele frequency- C:0.21NA EA 244
    rs623083721,2
    C--71106588(+) AATGTA/CCAGTT 1 -- us2k14Minor allele frequency- C:0.20NA EA 244
    rs1384740401,2
    --71106644(+) TGACAC/GCATGG 1 -- us2k10--------
    rs18424791,2
    C,F,O,A,H--71106679(+) AGAAAT/AGATTA 1 -- us2k1 trp331Minor allele frequency- A:0.28NS EA NA WA CSA 2919
    rs1899325951,2
    --71106704(+) TGTTCG/TTAAAA 1 -- us2k10--------
    rs1811507491,2
    --71106781(+) ATTCAA/GTACTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CSN3 (71108305 - 71117145 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CSN3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv822612CNV Loss20364138
    nsv879466CNV Loss21882294
    nsv829963CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CSN3
    DNA2.0 Custom Variant and Variant Library Synthesis for CSN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601695    OMIM disorders: --

    2 diseases for CSN3:    
    About MalaCards
    dentin sensitivity    mammary paget's disease

    2 diseases from the University of Copenhagen DISEASES database for CSN3:
    Dentin sensitivity     Hypersensitivity reaction type I disease

    Find genes that share disorders with CSN3           About GenesLikeMe

    8 Novoseek inferred disease relationships for CSN3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    allergy milk 82.8 1 12170271 (1)
    allergy food 39 1 9316283 (1)
    allergy 27.4 2 12170271 (2)
    dermatitis atopic 17 4 17106206 (2), 9316283 (1)
    tumors 0.6 2 7970700 (1)
    autoimmune diseases 0 1 1724453 (1)
    thrombosis 0 2 11242453 (2)
    carcinoma 0 2 7680194 (1), 8450194 (1)

    Genetic Association Database (GAD): CSN3
    Human Genome Epidemiology (HuGE) Navigator: CSN3 (1 document)

    Export disorders for CSN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CSN3 gene, integrated from 10 sources (see all 182):
    (articles sorted by number of sources associating them with CSN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure of the human kappa-casein gene. (PubMed id 8863730)1, 2, 3 Edlund A.... Hansson L. (Gene 1996)
    2. Structural features of a peptide corresponding to human kappa-casein residues 84-101 by 1H-nuclear magnetic resonance spectroscopy. (PubMed id 10191473)1, 2, 9 Plowman J.E.... Cross J.J. (J. Dairy Res. 1999)
    3. Cloning and sequencing of human kappa-casein cDNA. (PubMed id 1296818)1, 2, 9 Bergstroem S....Stroemqvist M. (DNA Seq. 1992)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Genomic organization and chromosomal localization of the human casein gene family. (PubMed id 9050925)1, 3 Fujiwara Y....Ueda M. (Hum. Genet. 1997)
    6. Preparation and amino acid sequence of human kappa-casein. (PubMed id 4018271)1, 2 Brignon G.... Ribadeau-Dumas B. (FEBS Lett. 1985)
    7. Localisation and importance of the sugar part of human casein. (PubMed id 7460900)1, 2 Fiat A.-M....Jolles P. (Eur. J. Biochem. 1980)
    8. Suspension of the calcium-sensitive human beta-caseins by human kappa-casein. (PubMed id 12146463)1, 9 Sood S.M. and Slatter C.W. (J. Dairy Sci. 2002)
    9. Rare variants in ischemic stroke: an exome pilot study. (PubMed id 22536414)1 Cole J.W....O'Connell J.R. (PLoS ONE 2012)
    10. Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)1 Satoh J....Tabunoki H. (Neuropathol. Appl. Neurobiol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1448 HGNC: 2446 AceView: CSN3 Ensembl:ENSG00000171209 euGenes: HUgn1448
    ECgene: CSN3 H-InvDB: CSN3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CSN3 Pharmacogenomics, SNPs, Pathways
    Protein Spotlighthttp://web.expasy.org/spotlight/back_issues/016

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CSN3 gene:
    Search GeneIP for patents involving CSN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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