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CSN2 Gene

protein-coding   GIFtS: 60
GCID: GC04M070869

Casein Beta


(Previous symbol: CASB)
  See CSN2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Casein Beta1 2
CASB1 2 3
beta-casein2

External Ids:    HGNC: 24471   Entrez Gene: 14472   Ensembl: ENSG000001352227   OMIM: 1154605   UniProtKB: P058143   

Export aliases for CSN2 gene to outside databases

Previous GC identifers: GC04M070731 GC04M071070 GC04M071136 GC04M071001 GC04M066618


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CSN2 Gene:
CSN2 (casein beta) is a protein-coding gene. Diseases associated with CSN2 include type 1 diabetes mellitus. GO annotations related to this gene include enzyme inhibitor activity and calcium ion binding.

UniProtKB/Swiss-Prot: CASB_HUMAN, P05814
Function: Important role in determination of the surface properties of the casein micelles

Gene Wiki entry for CSN2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CSN2 gene promoter:
         STAT5B   TBP   p53   AML1a   Evi-1   MEF-2A   POU2F1   POU2F1a   aMEF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSN2 promoter sequence
   Search Chromatin IP Primers for CSN2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21.1

CSN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSN2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M070869:  view genomic region     (about GC identifiers)

Start:
70,820,974 bp from pter      End:
70,826,726 bp from pter
Size:
5,753 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CASB_HUMAN, P05814 (See protein sequence)
Recommended Name: Beta-casein precursor  
Size: 226 amino acids; 25382 Da
Secondary accessions: Q4VAZ9 Q9UCM5

Explore the universe of human proteins at neXtProt for CSN2: NX_P05814

Explore proteomics data for CSN2 at MOPED

Post-translational modifications: 

  • Form 1-P is phosphorylated once; half of the molecules are phosphorylated on Ser-24, half on Ser-251
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CSN2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001882.1  
    ENSEMBL proteins: 
     ENSP00000341030  
    Reactome Protein details: P05814

    CSN2 Human Recombinant Protein Products:

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    ProSpec Recombinant Protein for CSN2
    Cloud-Clone Corp. Proteins for CSN2

     
    Search eBioscience for Proteins for CSN2 

     
    antibodies-online proteins for CSN2 (20 products) 

     
    antibodies-online peptides for CSN2

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    antibodies-online antibodies for CSN2 (40 products) 

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    Cloud-Clone Corp. ELISAs for CSN2
    Cloud-Clone Corp. CLIAs for CSN2
    Search eBioscience for ELISAs for CSN2 
    antibodies-online kits for CSN2 (20 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001588 Casein
     IPR016345 Casein_beta

    Graphical View of Domain Structure for InterPro Entry P05814

    ProtoNet protein and cluster: P05814

    1 Blocks protein domain: IPB001588 Casein

    UniProtKB/Swiss-Prot: CASB_HUMAN, P05814
    Similarity: Belongs to the beta-casein family


    Find genes that share domains with CSN2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CASB_HUMAN, P05814
    Function: Important role in determination of the surface properties of the casein micelles

         Genatlas biochemistry entry for CSN2:
    casein,beta

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004857enzyme inhibitor activity TAS2387396
    GO:0005215transporter activity IEA--
    GO:0005509calcium ion binding TAS2387396
         
    Find genes that share ontologies with CSN2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CSN2:
     Increased cell death in breast 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Csn2):
     endocrine/exocrine gland  integument  other 

    Find genes that share phenotypes with CSN2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Csn2tm1Psim for CSN2

       genOway: Develop your customized and physiologically relevant rodent model for CSN2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CSN2 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate CSN2:
    hsa-miR-203 hsa-miR-3671 hsa-miR-4264 hsa-miR-183* hsa-miR-145
    SwitchGear 3'UTR luciferase reporter plasmidCSN2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CSN2

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    Sino Biological Human cDNA Clone for CSN2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSN2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CASB_HUMAN, P05814: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    nucleus2
    chloroplast1
    cytoskeleton1
    cytosol1
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--

    Find genes that share ontologies with CSN2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CSN2 About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Prolactin Signaling Pathway
    Development Prolactin receptor signaling0.39
    Prolactin signaling pathway0.33
    2PI-3K cascade
    Signaling by ERBB40.66
    3Signaling by GPCR
    Signal Transduction0.58
    4ErbB4 Pathway
    Prolactin Signaling0.54
    5Signaling events mediated by PTP1B
    Signaling events mediated by PTP1B


    Find genes that share SuperPaths with CSN2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for CSN2
        Prolactin Signaling

    1 GeneGo (Thomson Reuters) Pathway for CSN2
        Development Prolactin receptor signaling

    2 BioSystems Pathways for CSN2
        Glucocorticoid receptor regulatory network
    Signaling events mediated by PTP1B


    1 Reactome Pathway for CSN2
        Nuclear signaling by ERBB4


    1 Kegg Pathway  (Kegg details for CSN2):
        Prolactin signaling pathway

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CSN2
    Interactions:

        Search GeneGlobe Interaction Network for CSN2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for CSN2 (P058142, 3 ENSP000003410304) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFYCQ139523, ENSP000003966204I2D: score=3 STRING: ENSP00000396620
    CSN3P074983, ENSP000003048224I2D: score=1 STRING: ENSP00000304822
    HTRA2O434643, ENSP000002580804I2D: score=1 STRING: ENSP00000258080
    NEK3P519563, ENSP000003832104I2D: score=1 STRING: ENSP00000383210
    NEK8Q86SG63, ENSP000002687664I2D: score=1 STRING: ENSP00000268766
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006816calcium ion transport TAS2387396
    GO:0043086negative regulation of catalytic activity TAS2387396

    Find genes that share ontologies with CSN2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CSN2 (CASB)

    Selected Novoseek inferred chemical compound relationships for CSN2 gene (see all 55)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    whey 75.4 26 15930449 (5), 16848557 (2), 11174844 (1), 14976147 (1) (see all 18)
    imac 68.8 8 15565681 (1), 17723369 (1), 10960913 (1), 17900103 (1)
    exorphins 66.1 1 1764604 (1)
    sodium caseinate 65.7 8 19505156 (2), 15542336 (1), 16080171 (1)
    glyceryl monooleate 59.7 9 16618167 (3), 15248719 (2), 17580860 (2), 12502394 (1)
    rennet 59.5 2 10905693 (1)
    monoacylglycerol 57.2 27 16471923 (5), 15248719 (4), 19127751 (4), 16618167 (3) (see all 7)
    phosphothreonine 56.7 2 11857762 (1)
    phosphoserine 56.3 4 19641788 (1), 11857762 (1), 18420601 (1)
    zirconia 43 1 17269746 (1)



    Find genes that share compounds with CSN2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CSN2 gene: 
    NM_001891.2  

    Unigene Cluster for CSN2:

    Casein beta
    Hs.2242  [show with all ESTs]
    Unigene Representative Sequence: NM_001891
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000353151(uc003hes.4 uc003het.4)
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate CSN2:
    hsa-miR-203 hsa-miR-3671 hsa-miR-4264 hsa-miR-183* hsa-miR-145
    SwitchGear 3'UTR luciferase reporter plasmidCSN2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CSN2
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CSN2
      QuantiTect SYBR Green Assays in human, mouse, rat CSN2
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    Additional mRNA sequence: 

    BC069554.1 BC096194.3 BC096195.1 BC096196.3 BC096197.3 X13766.1 X17070.1 X55739.1 

    1 DOTS entry:

    DT.407783 

    8 AceView cDNA sequences:

    BG184927 X55739 BG219803 BG208669 NM_001891 X13766 X17070 BC069554 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CSN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CSN2 Expression
    About this image

    CSN2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CSN2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.2242

    UniProtKB/Swiss-Prot: CASB_HUMAN, P05814
    Tissue specificity: Mammary gland specific. Secreted in milk

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CSN2 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Csn21 , 5 casein beta1, 5 66.67(n)1
    49.19(a)1
      5 (43.56 cM)5
    129911  NM_009972.21  NP_034102.11 
     876926245 


    ENSEMBL Gene Tree for CSN2 (if available)
    TreeFam Gene Tree for CSN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CSN2 (see all 201)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1164622171,2
    C,F--70820792(+) CTATAG/ACAAAT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs14914291,2
    C,F,O,H--70820800(+) AATGGG/AGTATA 1 -- int120Minor allele frequency- A:0.07NS EA NA WA CSA 932
    rs14914301,2
    C,F--70820814(+) GCATCC/TTTTCT 1 -- int15Minor allele frequency- T:0.04EA NA 158
    rs171478851,2
    C,F,H--70820946(+) ATTAGG/ATTTGA 1 -- int115Minor allele frequency- A:0.04NA NS EA WA 1628
    rs1862696221,2
    --70820947(+) TTAGGC/TTTGAA 1 -- int10--------
    rs26378161,2
    C,F--70821025(+) CTTAAA/GGAAAT 1 -- ut312Minor allele frequency- G:0.17NA EA 240
    rs1152928301,2
    C,F--70821064(+) TGTATA/GCATAT 1 -- ut311Minor allele frequency- G:0.02WA 118
    rs1474119871,2
    C--70821195(+) ATATA-/AAAT  
            
    AAATA
    1 -- ut310--------
    rs1473022441,2
    --70821207(+) TAAAGA/GGACAA 1 -- ut310--------
    rs1159398621,2
    C,F--70821232(+) ATATAA/CACTCA 1 -- ut311Minor allele frequency- C:0.04WA 118

    HapMap Linkage Disequilibrium report for CSN2 (70820974 - 70826726 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CSN2:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv5629n71CNV Loss21882294
    dgv5628n71CNV Loss21882294
    nsv879455CNV Loss21882294
    nsv879460CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CSN2
    DNA2.0 Custom Variant and Variant Library Synthesis for CSN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 115460    OMIM disorders: --

    1 disease for CSN2:    
    About MalaCards
    type 1 diabetes mellitus

    1 disease from the University of Copenhagen DISEASES database for CSN2:
    Breast cancer

    Find genes that share disorders with CSN2           About GenesLikeMe

    Selected Novoseek inferred disease relationships for CSN2 gene (see all 18)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    allergy milk 59.9 2 11678861 (2)
    autoimmune thyroid disease 17.2 3 8843812 (2), 12198602 (1)
    diabetes mellitus insulin-dependent 7.32 6 11015514 (2), 9662058 (2), 9230603 (1), 11850100 (1)
    breast cancer 5.98 4 15534001 (2), 9813040 (1), 18843297 (1)
    diabetes autoimmune 4.16 2 12198602 (2)
    carcinoma 4.13 1 9092813 (1)
    tumors 2.69 5 14976147 (1), 8440707 (1), 9537254 (1), 9374476 (1) (see all 5)
    immunodeficiency 2.47 1 16545061 (1)
    aids 1.82 2 11185556 (1), 16545061 (1)
    autoimmune diseases 0 1 12198602 (1)


    Export disorders for CSN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CSN2 gene, integrated from 10 sources (see all 363):
    (articles sorted by number of sources associating them with CSN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Regional localization of human beta-casein gene (CSN2) to 4pter-q21. (PubMed id 1577486)1, 3, 9 Menon R.S....Ham R.G. (Genomics 1992)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Structure of the human beta-casein encoding gene. (PubMed id 8112603)1, 2 Hansson L.... Bergstroem S. (Gene 1994)
    4. Cloning and sequencing of a cDNA encoding human milk beta-casein. (PubMed id 2387396)1, 2 Loennerdal B.... Hernell O. (FEBS Lett. 1990)
    5. Human beta-casein: partial cDNA sequence and apparent polymorphism. (PubMed id 2717418)1, 2 Menon R.S. and Ham R.G. (Nucleic Acids Res. 1989)
    6. Human beta-casein. Amino acid sequence and identification of phosphorylation sites. (PubMed id 6715339)1, 2 Greenberg R.... Dower H.J. (J. Biol. Chem. 1984)
    7. New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors. (PubMed id 12788072)1, 9 Ohashi A....Katunuma N. (Biochem. Biophys. Res. Commun. 2003)
    8. Assignment of the gene for beta-casein (CSN2) to 4q13 --&gt; q21 in humans and 3p13 --&gt; p12 in chimpanzees. (PubMed id 8565637)1, 9 McConkey E.H....Sutherland G.R. (Cytogenet. Cell Genet. 1996)
    9. Derivatives of human beta-casein fragments (54-59) exhibit highly potent immunosuppressant activity. (PubMed id 19463972)1, 9 Puri A....Haq W. (Int. Immunopharmacol. 2009)
    10. Reconstituted micelle formation using reduced, carboxymethylated bovine kappa-casein and human beta-casein. (PubMed id 16947075)1, 9 Sood S.M....Slattery C.W. (Protein J. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1447 HGNC: 2447 AceView: CSN2 Ensembl:ENSG00000135222 euGenes: HUgn1447
    ECgene: CSN2 Kegg: 1447 H-InvDB: CSN2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CSN2 Pharmacogenomics, SNPs, Pathways
    Protein Spotlighthttp://web.expasy.org/spotlight/back_issues/016

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CSN2 gene:
    Search GeneIP for patents involving CSN2

    GeneCards and IP:
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