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CSN1S1 Gene

protein-coding   GIFtS: 50
GCID: GC04P070845

Casein Alpha S1

(Previous names: casein, alpha)
(Previous symbols: CASA, CSN1)
  See CSN1S1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Casein Alpha S11 2
CSN11 2 3 5
CASA1 2 3
Casein, Alpha1 2
alpha-S1-casein2

External Ids:    HGNC: 24451   Entrez Gene: 14462   Ensembl: ENSG000001265457   OMIM: 1154505   UniProtKB: P477103   

Export aliases for CSN1S1 gene to outside databases

Previous GC identifers: GC04P071046 GC04P071113 GC04P071114 GC04P070977 GC04P066594


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CSN1S1 Gene:
CSN1S1 (casein alpha s1) is a protein-coding gene. Diseases associated with CSN1S1 include nocardiosis, and autoimmune enteropathy. GO annotations related to this gene include transporter activity.

UniProtKB/Swiss-Prot: CASA1_HUMAN, P47710
Function: Important role in the capacity of milk to transport calcium phosphate
Function: Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors

Gene Wiki entry for CSN1S1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CSN1S1 gene promoter:
         GATA-3   ATF-2   CUTL1   GATA-1   GATA-2   CRE-BP1   POU2F1   POU2F1b   POU2F1a   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSN1S1 promoter sequence
   Search Chromatin IP Primers for CSN1S1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CSN1S1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21.1

CSN1S1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSN1S1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P070845:  view genomic region     (about GC identifiers)

Start:
70,796,799 bp from pter      End:
70,812,289 bp from pter
Size:
15,491 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CASA1_HUMAN, P47710 (See protein sequence)
Recommended Name: Alpha-S1-casein precursor  
Size: 185 amino acids; 21671 Da
Subunit: Heteromultimers of alpha-s1 casein and kappa-casein; disulfide-linked
Miscellaneous: In milk, the alpha s1- and beta-caseins precipitate in presence of calcium (so-called
calcium-sensitive caseins). Kappa-casein prevents the precipitation of the other caseins by calcium through the
formation of large stable colloidal particles termed micelles
Secondary accessions: A1A510 A1A511 E9PB60 Q4PNR5
Alternative splicing: 4 isoforms:  P47710-1   P47710-2   P47710-3   P47710-4   

Explore the universe of human proteins at neXtProt for CSN1S1: NX_P47710

Explore proteomics data for CSN1S1 at MOPED

Post-translational modifications: 

  • Not glycosylated1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CSN1S1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001020275.1  NP_001881.1  

    ENSEMBL proteins: 
     ENSP00000246891   ENSP00000422611   ENSP00000427490   ENSP00000426684   ENSP00000421314  
     ENSP00000413157  

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    Novus Biologicals CSN1S1 Protein
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CSN1S1 

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    Search eBioscience for ELISAs for CSN1S1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001588 Casein
     IPR026999 Alpha-s1_casein

    Graphical View of Domain Structure for InterPro Entry P47710

    ProtoNet protein and cluster: P47710

    1 Blocks protein domain: IPB001588 Casein

    UniProtKB/Swiss-Prot: CASA1_HUMAN, P47710
    Similarity: Belongs to the alpha-casein family


    Find genes that share domains with CSN1S1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CASA1_HUMAN, P47710
    Function: Important role in the capacity of milk to transport calcium phosphate
    Function: Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
         
    Find genes that share ontologies with CSN1S1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CSN1S1:
     Synthetic lethal with Ras 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Csn1s1):
     endocrine/exocrine gland  integument 

    Find genes that share phenotypes with CSN1S1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Csn1s1tm1Afk for CSN1S1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CSN1S1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CSN1S1
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    miRNA
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    1 qRT-PCR Assays for microRNA that regulate CSN1S1:
    hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidCSN1S1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CASA1_HUMAN, P47710: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytoskeleton3
    cytosol3
    nucleus3
    plasma membrane3
    endoplasmic reticulum2
    golgi apparatus2
    mitochondrion2
    vacuole2
    chloroplast1
    endosome1
    lysosome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with CSN1S1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CSN1S1
    Interactions:

        Search GeneGlobe Interaction Network for CSN1S1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for CSN1S1 (P477103 ENSP000002468914) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929053, ENSP000003505124I2D: score=1 STRING: ENSP00000350512
    CPSF1Q105703, ENSP000003393534I2D: score=1 STRING: ENSP00000339353
    HTRA2O434643, ENSP000002580804I2D: score=1 STRING: ENSP00000258080
    STK4Q130433, ENSP000003618924I2D: score=1 STRING: ENSP00000361892
    TTBK1Q5TCY13, ENSP000002597504I2D: score=1 STRING: ENSP00000259750
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CSN1S1 (CASA1)

    1 HMDB Compound for CSN1S1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Selected Novoseek inferred chemical compound relationships for CSN1S1 gene (see all 154)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    whey 93.8 577 12617395 (9), 19589961 (8), 12617598 (7), 17109475 (7) (see all 99)
    rennet 91.1 64 12416796 (4), 10717847 (4), 15323482 (3), 10905693 (3) (see all 31)
    sodium caseinate 87.2 29 17630759 (2), 7738243 (2), 7593828 (2), 10564038 (1) (see all 15)
    calcium caseinate 79.4 3 2054060 (1), 14521035 (1), 16277399 (1)
    exorphins 78.5 6 11461171 (1), 18411161 (1), 9216246 (1), 12197782 (1) (see all 6)
    glucono-delta-lactone 74.9 5 15285105 (2), 11233022 (1), 19592288 (1)
    dnp-peptide 69.2 2 1650234 (1), 1659460 (1)
    lactose 67.6 59 15315384 (2), 1907301 (2), 12897287 (2), 16434457 (2) (see all 46)
    gliadin 66 44 14611720 (4), 9314097 (3), 9784660 (3), 7737562 (2) (see all 25)
    gluten 63.2 56 12153499 (4), 18425890 (4), 16685183 (3), 15106205 (3) (see all 34)



    Find genes that share compounds with CSN1S1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CSN1S1 gene (2 alternative transcripts): 
    NM_001025104.1  NM_001890.1  

    Unigene Cluster for CSN1S1:

    Casein alpha s1
    Hs.3155  [show with all ESTs]
    Unigene Representative Sequence: NM_001890
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000246891(uc003hep.1 uc003her.1) ENST00000507763 ENST00000507772
    ENST00000505782 ENST00000510936 ENST00000444405(uc003heq.1)
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate CSN1S1:
    hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidCSN1S1 3' UTR sequence
    Inhib. RNA
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    Primer
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    Additional mRNA sequence: 

    BC128227.1 BC128228.1 DQ064604.1 U23157.1 X78416.1 X98084.1 

    3 DOTS entries:

    DT.91693718  DT.91693723  DT.121273972 

    14 AceView cDNA sequences:

    X78416 NM_001890 BG199031 BG187562 BG205233 U23157 BG187172 BG206324 
    X98084 BG217918 BG207337 BG181959 BG217390 BG200584 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CSN1S1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTACAGTGGT
    CSN1S1 Expression
    About this image

    CSN1S1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CSN1S1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.3155

    UniProtKB/Swiss-Prot: CASA1_HUMAN, P47710
    Tissue specificity: Mammary gland specific. Secreted in milk

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CSN1S1 gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Csn1s15 casein alpha s1   --   5 (43.56 cM) 87666224 


    ENSEMBL Gene Tree for CSN1S1 (if available)
    TreeFam Gene Tree for CSN1S1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CSN1S1 (see all 484)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1832877471,2
    --70794884(+) TTGCCA/CAGGCC 2 -- us2k10--------
    rs1890784941,2
    --70794912(+) TGAATA/GGGAGT 2 -- us2k10--------
    rs1435484701,2
    --70794955(+) TTTCAA/CAGGGA 2 -- us2k10--------
    rs12208431,2
    C,F,H--70794993(-) agccaG/Atatca 2 -- us2k12Minor allele frequency- A:0.50NA 4
    rs1926344381,2
    --70795102(+) AAAGGA/CCTTTT 2 -- us2k10--------
    rs562758001,2
    C--70795168(+) TATTAC/TGTTTA 2 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1848392981,2
    --70795170(+) TTACGG/TTTATT 2 -- us2k10--------
    rs1464765211,2
    --70795282(+) TTTATA/TGAGGA 2 -- us2k10--------
    rs1390597071,2
    C--70795327(+) AAAATC/TCTTTT 2 -- us2k10--------
    rs1166468141,2
    F--70795341(+) GTTGTG/TTCTCT 2 -- us2k11Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for CSN1S1 (70796799 - 70812289 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CSN1S1:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv5629n71CNV Loss21882294
    nsv879454CNV Loss21882294
    dgv5628n71CNV Loss21882294
    nsv879455CNV Loss21882294
    nsv879460CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CSN1S1
    DNA2.0 Custom Variant and Variant Library Synthesis for CSN1S1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 115450    OMIM disorders: --

    12 diseases for CSN1S1:    
    About MalaCards
    nocardiosis    autoimmune enteropathy    enamel erosion    eosinophilic gastroenteritis
    denture stomatitis    lactose intolerance    gastroenteritis    dental caries
    pellagra    ovarian mucinous neoplasm    mycetoma    meniere's disease

    13 diseases from the University of Copenhagen DISEASES database for CSN1S1:
    Hypersensitivity reaction type I disease     Amyloidosis     Mastitis     protein-energy malnutrition
    Dental caries     Enamel erosion     Vascular disease     Diarrhea
    Atopic dermatitis     Diabetes mellitus     Breast cancer     Pellagra
    Kidney disease

    Find genes that share disorders with CSN1S1           About GenesLikeMe

    Selected Novoseek inferred disease relationships for CSN1S1 gene (see all 89)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    allergy milk 88.7 30 20212353 (3), 10400857 (2), 11193464 (2), 9291294 (2) (see all 19)
    allergy food 65.9 4 9316283 (2), 14980195 (1)
    allergy 54.4 31 10400857 (3), 11193464 (3), 20015589 (2), 7978534 (2) (see all 21)
    dermatitis atopic 48.2 9 7532192 (1), 7492156 (1), 9316283 (1), 9027438 (1) (see all 8)
    encephalopathy chronic 36.9 1 2204661 (1)
    atopy 33.3 7 15829656 (1), 12512191 (1), 17300640 (1), 12642834 (1) (see all 5)
    enterocolitis 32.7 3 8258625 (1), 7532192 (1), 19650428 (1)
    allergic reaction 32.6 2 12012792 (1), 9316283 (1)
    autistic 29.7 8 17974154 (1), 15294752 (1), 18425890 (1), 12197782 (1) (see all 6)
    protein-energy malnutrition 24.4 9 12888117 (1), 15356995 (1), 12619051 (1), 7638725 (1)


    Export disorders for CSN1S1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CSN1S1 gene, integrated from 10 sources (see all 1213):
    (articles sorted by number of sources associating them with CSN1S1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of three types of human alpha s1-casein mRNA transcripts. (PubMed id 7619062)1, 2, 3, 9 Johnsen L.B.... Berglund L. (Biochem. J. 1995)
    2. Genomic organization and chromosomal localization of the human casein gene family. (PubMed id 9050925)1, 2, 3 Fujiwara Y....Ueda M. (Hum. Genet. 1997)
    3. Human alpha S1-casein like protein: purification and N-terminal sequence determination. (PubMed id 8192860)1, 2 Cavaletto M.... Conti A. (Biol. Chem. Hoppe-Seyler 1994)
    4. Analysis of the human casein phosphoproteome by 2-D electrophoresis and MALDI-TOF/TOF MS reveals new phosphoforms. (PubMed id 18847231)2, 9 Poth A.G.... Holland J.W. (J. Proteome Res. 2008)
    5. On studying protein phosphorylation patterns using bottom-up LC- MS/MS: the case of human alpha-casein. (PubMed id 17646876)2, 9 Kjeldsen F.... Zubarev R.A. (Analyst 2007)
    6. A surface plasmon resonance study of the interactions between the component subunits of protein kinase CK2 and two protein substrates, casein and calmodulin. (PubMed id 11827172)1, 9 BenA-tez M.J....JimAcnez J.S. (Mol. Cell. Biochem. 2001)
    7. Human alpha s1-casein: purification and characterization. (PubMed id 7749638)2, 9 Rasmussen L.K.... Petersen T.E. (Comp. Biochem. Physiol. 1995)
    8. Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1. (PubMed id 22474075)1 Gastaldello S....Masucci M.G. (J Mol Cell Biol 2012)
    9. Insulin autoantibodies with high affinity to the bovine milk protein alpha casein. (PubMed id 21361910)1 Adler K....Bonifacio E. (Clin. Exp. Immunol. 2011)
    10. Casein I+ s1 is expressed by human monocytes and upregulates the production of GM-CSF via p38 MAPK. (PubMed id 21135174)1 VordenbAoumen S....Schneider M. (J. Immunol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1446 HGNC: 2445 AceView: CSN1S1 Ensembl:ENSG00000126545 euGenes: HUgn1446
    ECgene: CSN1S1 H-InvDB: CSN1S1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CSN1S1 Pharmacogenomics, SNPs, Pathways
    Protein Spotlighthttp://web.expasy.org/spotlight/back_issues/016

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CSN1S1 gene:
    Search GeneIP for patents involving CSN1S1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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