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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CSGALNACT2 Gene

protein-coding GIFtS: 52
GCID: GC10P043633

chondroitin sulfate N-acetylgalactosaminyltransferase 2

Explore 2 diseases affiliated with
CSGALNACT2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Chondroitin Sulfate N-Acetylgalactosaminyltransferase 2¹ ²		Beta 4 GalNAcT-2²
GALNACT2¹ ² ³		Chondroitin Beta1,4 N-Acetylgalactosaminyltransferase 2²
GALNACT-2¹ ²		Beta4GalNAcT-2³
CHGN2² ³		EC 2.4.1.174³
MGC40204¹		GalNAcT-2³
PRO0082¹		Chondroitin Beta-1,4-N-Acetylgalactosaminyltransferase 2³

External Ids:	HGNC: 24292¹	Entrez Gene: 55454²	Ensembl: ENSG00000169826⁷	UniProtKB: Q8N6G5³

Export aliases for CSGALNACT2 gene to outside databases

Previous GC identifers: GC10P042954 GC10P040176

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CSGALNACT2:

This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved

in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X.

(provided by RefSeq, Dec 2012)

UniProtKB/Swiss-Prot: CGAT2_HUMAN, Q8N6G5

Function: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid

(GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of

chondroitin chains

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_033985.7

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CSGALNACT2 gene promoter:
AhR NF-1 RFX1 AML1a CUTL1 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 MZF-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CSGALNACT2 promoter sequence

Search SABiosciences Chromatin IP Primers for CSGALNACT2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSGALNACT2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.21 Ensembl cytogenetic band: 10q11.21 HGNC cytogenetic band: 10q11.21

CSGALNACT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSGALNACT2 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P043633: view genomic region (about GC identifiers)

Start:	43,633,934 bp from pter	End:	43,680,756 bp from pter
Size:	46,823 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CGAT2_HUMAN, Q8N6G5 (See protein sequence)

Recommended Name: Chondroitin sulfate N-acetylgalactosaminyltransferase 2

Size: 542 amino acids; 62572 Da

Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable)

Sequence caution: Sequence=AAF71068.1; Type=Erroneous initiation;

Secondary accessions: B3KWL7 Q6MZJ5 Q6MZP6 Q8TCH4 Q9P1I6

Alternative splicing: 2 isoforms: Q8N6G5-1 Q8N6G5-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CSGALNACT2: NX_Q8N6G5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N6G5

CSGALNACT2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_061060.3

ENSEMBL proteins:

ENSP00000363590 ENSP00000363588

Reactome Protein details: Q8N6G5
Human Recombinant Protein Products:

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	Uscn Proteins for CSGALNACT2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0030173	integral to Golgi membrane	NAS	11788602
GO:0032580	Golgi cisterna membrane	IEA	--

CSGALNACT2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CSGALNACT2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CSGALNACT2 for domains About GeneDecksing

1 InterPro domain/family:

IPR008428 Chond_GalNAc

Graphical View of Domain Structure for InterPro Entry Q8N6G5

ProtoNet protein and cluster: Q8N6G5

UniProtKB/Swiss-Prot: CGAT2_HUMAN, Q8N6G5

Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CGAT2_HUMAN, Q8N6G5

Function: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid

(GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of

chondroitin chains

Catalytic activity: UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-proteoglycan = UDP +

N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-(1->3)-beta-D-galactosylproteoglycan

Enzyme Number (IUBMB): EC 2.4.1.174¹

miRNA Products:		OriGene 3'-UTR Clone: CSGALNACT2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSGALNACT2
		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate CSGALNACT2 (see all 11):
		hsa-miR-3163 hsa-miR-217 hsa-miR-520f hsa-miR-1263 hsa-miR-125a-3p hsa-miR-512-3p hsa-miR-373* hsa-miR-583

		SwitchGear 3'UTR luciferase reporter plasmid: CSGALNACT2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSGALNACT2

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008376	acetylgalactosaminyltransferase activity	IDA	11788602
GO:0046872	metal ion binding	IEA	--
GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	IEA	--

CSGALNACT2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for CSGALNACT2:

Synthetic lethal with c-Myc af

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/14 pathways (see all 14)
MPS VI - Maroteaux-Lamy syndrome	1.00	MPS VII - Sly syndrome	1.00
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS I - Hurler syndrome	1.00	MPS IIID - Sanfilippo syndrome D	1.00
Mucopolysaccharidoses	1.00	MPS IX - Natowicz syndrome	1.00

dermatan sulfate biosynthesis

dermatan sulfate biosynthesis	1.00	chondroitin and dermatan biosynthesis	0.38
Glycosaminoglycan biosynthesis - chondroitin sulfate	0.73	chondroitin sulfate biosynthesis (late stages)	0.32
chondroitin sulfate biosynthesis	0.64	Chondroitin sulfate biosynthesis	0.24

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Disease

Disease

1.00

A tetrasaccharide linker sequence is required for GAG synthesis

Chondroitin sulfate/dermatan sulfate metabolism

0.54

Pathway sources
See GeneCards unified pathways
Show all pathways

4 BioSystems Pathways for CSGALNACT2

	chondroitin sulfate biosynthesis (late stages)
	chondroitin and dermatan biosynthesis
	chondroitin sulfate biosynthesis
	dermatan sulfate biosynthesis

5/18 Reactome Pathways for CSGALNACT2 (see all 18)

	Chondroitin sulfate/dermatan sulfate metabolism
	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	MPS II - Hunter syndrome

2 Kegg Pathways (Kegg details for CSGALNACT2):

	Glycosaminoglycan biosynthesis - chondroitin sulfate
	Metabolic pathways

CSGALNACT2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CSGALNACT2

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

5/9 Interacting proteins for CSGALNACT2 (ENSP00000363590⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B3GAT1	ENSP00000307875⁴	STRING: ENSP00000307875
B3GAT2	ENSP00000230053⁴	STRING: ENSP00000230053
B3GAT3	ENSP00000265471⁴	STRING: ENSP00000265471
CHPF	ENSP00000243776⁴	STRING: ENSP00000243776
CHPF2	ENSP00000035307⁴	STRING: ENSP00000035307

About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0030166	proteoglycan biosynthetic process	IDA	11788602
GO:0030203	glycosaminoglycan metabolic process	TAS	--
GO:0030204	chondroitin sulfate metabolic process	TAS	--
GO:0030206	chondroitin sulfate biosynthetic process	TAS	--

CSGALNACT2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CSGALNACT2

2 HMDB Compounds for CSGALNACT2 About this table

Compound	Synonyms	CAS #	PubMed Ids
Manganese	manganese	7439-96-5	--
Uridine diphosphate-N-acetylgalactosamine	UDP-N-acetyl-D-galactosamine (see all 17)	7277-98-7	--

Search CenterWatch for drugs/clinical trials and news about CSGALNACT2 / CGAT2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CSGALNACT2 gene:

NM_018590.4

Unigene Cluster for CSGALNACT2:

Chondroitin sulfate N-acetylgalactosaminyltransferase 2

Hs.657569 [show with all ESTs]

Unigene Representative Sequence: BX647369

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000374466(uc001jan.3) ENST00000374464(uc001jam.1)

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		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate CSGALNACT2 (see all 11):
		hsa-miR-3163 hsa-miR-217 hsa-miR-520f hsa-miR-1263 hsa-miR-125a-3p hsa-miR-512-3p hsa-miR-373* hsa-miR-583

		SwitchGear 3'UTR luciferase reporter plasmid: CSGALNACT2 3' UTR sequence

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Additional cDNA sequence:

AB079252.1 AB090811.1 AF086458.1 AF116646.1 AK074474.1 AK125300.1 BC030268.1 BX640967.1

BX641073.1 BX647369.1

8 DOTS entries:

DT.313056 DT.99987843 DT.95218930 DT.121238832 DT.75124647 DT.87009799 DT.75138315 DT.95367561

24/127 AceView cDNA sequences (see all 127):

AA748617 BF431097 AI674924 AV729184 AA825719 AA721408 BQ437930 AI902340

AA235741 CA390490 BX102005 Z41557 AB079252 CD365706 AW471241 AA773203

AF086458 AA321947 NM_018590 D79651 BX094189 AI673813 BC030268 AK125300

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CSGALNACT2 (see all 7) About this scheme

ExUns:	1	^	2a	·	2b	·	2c	^	3a	·	3b	^	4	^	5a	·	5b	^	6a	·	6b	^	7a	·	7b	^	8a	·	8b	^	9	^	10	^	11
SP1:																			-						-
SP2:																			-
SP3:																							-		-
SP4:																															-
SP5:			-		-		-

ECgene alternative splicing isoforms for CSGALNACT2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CSGALNACT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATCTGTTAC

About this image
See CSGALNACT2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CSGALNACT2

SOURCE GeneReport for Unigene cluster: Hs.657569

UniProtKB/Swiss-Prot: CGAT2_HUMAN, Q8N6G5

Tissue specificity: Ubiquitous

SABiosciences Custom PCR Arrays for CSGALNACT2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSGALNACT2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CSGALNACT2 gene from 4/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CSGALNACT2¹	chondroitin sulfate N-acetylgalactosaminyltransferase more	78.81(n) 86.62(a)		423632 XM_421516.3 XP_421516.2
lizard (Anolis carolinensis)	Reptilia	CSGALNACT2⁶	--	85(a)	1 ↔ 1	GL343233.1(709378-730863)
zebrafish (Danio rerio)	Actinopterygii	BU744178.1²	--	82.08(n)		337862 BU744178.1
fruit fly (Drosophila melanogaster)	Insecta	CG12913⁶	--	36(a)	1 → many	2R(6136762-6142479)

ENSEMBL Gene Tree for CSGALNACT2 (if available)
TreeFam Gene Tree for CSGALNACT2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CSGALNACT2 gene

CSGALNACT1² CHSY3² CHPF² CHPF2² CHSY1²

2 SIMAP similar genes for CSGALNACT2 using alignment to 1 protein entry: CGAT2_HUMAN:

CSGALNACT1 ChGn

CSGALNACT2 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for CSGALNACT2
PGOHUM00000241908 PGOHUM00000250082

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs142405913^1,2		--	43631950(+)	`CTAGAA/GATGCC`	1	--	us2k¹		0	--	--	--	--
rs145933519^1,2		--	43631966(+)	`AATGAA/GAATCA`	1	--	us2k¹		0	--	--	--	--
rs74579327^1,2	C,F,	--	43632021(+)	`CTCCAC/TGCAGA`	1	--	us2k¹		1		EA	120
rs191252775^1,2		--	43632176(+)	`AAAACC/TGTGGA`	1	--	us2k¹		0	--	--	--	--
rs142020655^1,2	C,	--	43632223(+)	`CAGGG-/GAATCAG`	1	--	us2k¹		0	--	--	--	--
rs115426020^1,2	F,	--	43632415(+)	`ATTTTA/TCAACT`	1	--	us2k¹		1		WA	118
rs138618618^1,2		--	43632660(+)	`CGCTTC/GAGCCC`	1	--	us2k¹		0	--	--	--	--
rs35987671^1,2	C,	--	43632713(+)	`CTACC-/AAAAAA`	1	--	us2k¹		0	--	--	--	--
rs184351592^1,2		--	43632773(+)	`TACTCA/GGGAGG`	1	--	us2k¹		0	--	--	--	--
rs189731984^1,2		--	43632891(+)	`TAGATG/TAATAA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CSGALNACT2 (43633934 - 43680756 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CSGALNACT2
2 CNVs: 23386 70976

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSGALNACT2

DNA2.0 Custom Variant and Variant Library Synthesis for CSGALNACT2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CSGALNACT2 for disorders About GeneDecksing

2 diseases for CSGALNACT2: About MalaCards

hirschsprung's disease alzheimer's disease

Human Genome Epidemiology (HuGE) Navigator: CSGALNACT2 (1 document)

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CSGALNACT2 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with CSGALNACT2)

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Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate. (PubMed id 12446672)^{1, 2, 3} Sato T.... Narimatsu H. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Molecular cloning and expression of a second chondroitin N- acetylgalactosaminyltransferase involved in the initiation and elongation of chondroitin/dermatan sulfate. (PubMed id 12433924)^{1, 2} Uyama T.... Sugahara K. (2003)
Simultaneous siRNA-mediated silencing of pairs of gene s coding for enzymes involved in glycosaminoglycan synthesis. (PubMed id 22590693)¹ Dziedzic D....Jakobkiewicz-Banecka J. (2012)
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. (PubMed id 19196962)¹ Garcia-Barcelo M.M....Tam P.K. (2009)
Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells. (PubMed id 19298595)¹ Bret C....Klein B. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)¹ Grupe A....Goate A. (2006)
Molecular cloning and expression of human chondroitin N- acetylgalactosaminyltransferase: key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate. (PubMed id 11788602)¹ Uyama T.... Sugahara K. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55454	HGNC: 24292	AceView: GALNACT-2	Ensembl:ENSG00000169826	euGenes: HUgn55454
ECgene: CSGALNACT2	Kegg: 55454	H-InvDB: CSGALNACT2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CSGALNACT2	Pharmacogenomics, SNPs, Pathways
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_478

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CSGALNACT2 Gene

chondroitin sulfate N-acetylgalactosaminyltransferase 2

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CSGALNACT2 Gene

chondroitin sulfate N-acetylgalactosaminyltransferase 2

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