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CSF2RB Gene

protein-coding GIFtS: 66

GC22P035642

colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: IL3RB)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
CD131 ^¹, ²
CDw131 ^², ³
IL3RB ^², ³
IL5RB ^¹, ², ³

Descriptions
CD131 antigen ^³
GM-CSF/IL-3/IL-5 receptor common beta-chain ^², ³
colony stimulating factor 2 receptor, beta ^²
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) ^²
colony-stimulating factor-2 receptor, beta, low-affinity ^²
cytokine receptor common subunit beta ^²
interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity) ^²

External Ids
HGNC: 2436¹
Entrez Gene: 1439²
UniProtKB: P32927³
Ensembl: ENSG00000100368⁷

Search outside databases for aliases for CSF2RB gene

Previous GC identifers: GC22P033932 GC22P035552 GC22P035561

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CSF2RB:

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3,

IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar

proteinosis (PAP). [provided by RefSeq]

UniProtKB/Swiss-Prot: IL3RB_HUMAN, P32927

Function: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage

colony-stimulating factor

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CSF2RB gene

Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q12.3 HGNC cytogenetic band: 22q12.2-q13.1

CSF2RB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P035642: (about GC identifiers)

Start:	35,639,616 bp from pter
End:	35,666,437 bp from pter
Size:	26,822 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: IL3RB_HUMAN, P32927 (See protein sequence)

Recommended Name: Cytokine receptor common subunit beta precursor

Size: 897 amino acids; 97336 Da

Subunit: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and

GM-CSF receptors

Subcellular location: Membrane; Single-pass type I membrane protein

PDB structures from and Proteopedia :

1C8P (3D)

1EGJ (3D)

1GH7 (3D)

2GYS (3D)

3CXE (3D)

Secondary accessions: Q5JZI1 Q6ICE0

Alternative splicing: 2 isoforms: P32927-1 P32927-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_000386.1

ENSEMBL proteins:

ENSP00000262825 ENSP00000385271 ENSP00000384053

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (IL3RB)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex	TAS	9410898

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Antibodies for CSF2RB:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	R&D Systems Antibodies for CSF2RB (Common beta Chain)
	Antibodies from Abcam (IL3RB), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CSF2RB)
	Novus Biologicals Antibodies for CSF2RB

Assays for CSF2RB:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P32927

ProtoNet protein and cluster: P32927

1 Blocks protein family: IPB003531 Short hematopoietin receptor

UniProtKB/Swiss-Prot: IL3RB_HUMAN, P32927

Domain: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient

intracellular transport and cell-surface receptor binding

Domain: The box 1 motif is required for JAK interaction and/or activation

Similarity: Belongs to the type I cytokine receptor family. Type 4 subfamily

Similarity: Contains 2 fibronectin type-III domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CSF2RB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CSF2RB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000395

Applied Biosystems Silencer® siRNAs for CSF2RB

Sigma-Aldrich siRNA and siRNA Panels for CSF2RB

Sigma-Aldrich shRNA Panels and shRNA for CSF2RB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CSF2RB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000395
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000395
untagged cDNA clone in CMV expression vector: NM_000395

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000395

UniProtKB/Swiss-Prot: IL3RB_HUMAN, P32927

Function: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage

colony-stimulating factor

Genatlas biochemistry entry for CSF2RB:

colony-stimulating factor 2 (granulocyte,macrophage), interleukin 3,interleukin 5 receptor common

subunit beta (high affinity),critical for the activation of both the JAK/STAT (JAK2,STAT5) and MAP

kinase pathways,involved in LYN binding

3 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Csf2rb):

hematopoietic system

immune system

respiratory system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	TAS	9410898
GO:0004912	contributes to interleukin-3 receptor activity	TAS	9410898
GO:0004914	contributes to interleukin-5 receptor activity	TAS	9410898
GO:0005515	protein binding	IPI	17828305

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for CSF2RB (Your Favorite Gene powered by Ingenuity)

GM-CSF Signaling
Acute Myeloid Leukemia Signaling
IL-3 Signaling
RAR Activation

GeneDecks CSF2RB for the pathways selected above

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5/64 Interacting proteins for CSF2RB (ENSP00000262825³ P32927¹) via UniProtKB, MINT, and/or STRING (see all 64 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CSF2	P04141¹	STRING (score=.999) EBI-1809771, EBI-1809826
JAK2	O60674¹	STRING (score=.999) EBI-1809771, EBI-518647
IL3	P08700¹	EBI-1809771, EBI-1811718
CSF2RA	ENSP00000370920³	STRING (score=.999)
SHC1	ENSP00000357432³	STRING (score=.998)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	NAS	1702217
GO:0007585	respiratory gaseous exchange	TAS	9410898
GO:0019221	cytokine-mediated signaling pathway	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CSF2RB

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CSF2RB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CSF2RB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000395

Sigma-Aldrich siRNA and siRNA Panels for CSF2RB

Sigma-Aldrich shRNA Panels and shRNA for CSF2RB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000395

REFSEQ mRNAs for CSF2RB gene:

NM_000395.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000395

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000395
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000395
                                 untagged cDNA clone in CMV expression vector: NM_000395

Additional cDNA sequence:

AK302993.1 BC070085.1 CR456428.1 CR604461.1 M59941.1

5 DOTS entries:

DT.99935002 DT.100744002 DT.101956029 DT.100687954 DT.453853

24/112 AceView cDNA sequences (see all 112 ):

CR456428 C01377 AA847136 CR604461 AI379138 M59941 BF002507 AA960845

BC070085 H55302 CA448651 CA306570 AU185738 BX450991 BU617730 AA768316

CA428322 AA761543 AI523112 AA279147 AI718599 NM_000395 CD608389 BG002017

highest scoring ESTs for CSF2RB:

M59941 AA001063 BI059234 BQ342799 CA406713 CR456428 D58877 H55302 AL540399 AV756141

Unigene Cluster for CSF2RB:

Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Hs.592192 [show with all ESTs]

Unigene Representative Sequence: NM_000395

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CSF2RB

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13	^	14
SP1:					-														-
SP2:					-
SP3:

About this scheme

ECgene alternative splicing isoforms for CSF2RB

3 Ensembl transcripts including schematic representations:

ENST00000262825 ENST00000406230 ENST00000403662

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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CSF2RB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CSF2RB

¹ / ² / ³

5 probe-sets matching CSF2RB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37494_at²^{, 3}	U95-A	1	1.00	1.00	0.67	0.73	M59941	1.00	1.00	1.00	1
37493_at²^{, 3}	U95-A	1	1.00	1.00	0.97	1.29	H04668	0.60	1.00	0.82	1
1086_at²^{, 3}	U95-A	1	1.00	1.00	0.01	0.38	M59941	1.00	1.00	1.00	1
205159_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AV756141	0.60	1.00	0.82	1
205159_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CSF2RB for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TACCTGAAGT

SOURCE GeneReport for Unigene cluster: Hs.592192
Expression variation in blood from EXPOLDB for CSF2RB

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CSF2RB gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CSF2RB¹	--	colony stimulating factor 2 receptor, beta, low-affinity more	77.27(n) 65.8(a)	481276 XM_538397.2 XP_538397.2
chimpanzee (Pan troglodytes)	CSF2RB¹	--	colony stimulating factor 2 receptor, beta, low-affinity more	98.33(n) 97.73(a)	458802 XM_001145357.1 XP_001145357.1
cow (Bos taurus)	CSF2RB¹	--	colony stimulating factor 2 receptor, beta, low-affinity more	77.1(n) 66.78(a)	528530 XM_606956.3 XP_606956.3
rat (Rattus norvegicus)	Csf2rb¹	--	colony stimulating factor 2 receptor, beta, low-affinity more	70.22(n) 56.45(a)	171081 NM_133555.1 NP_598239.1
mouse (Mus musculus)	Csf2rb⁵ Csf2rb2¹	15 (43.30 cM)⁵	colony stimulating factor 2 receptor, beta, low-affinity more⁵ colony stimulating factor 2 receptor, beta 2, low-affinity more¹	69.88(n)¹ 57.57(a)¹	12984¹ NM_007781.2¹ NP_031807.1¹ AF483496⁵ AF483497⁵ (see all 38)

About this table Species with no ortholog for CSF2RB

ENSEMBL Gene Tree for CSF2RB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/134 NCBI SNPs in CSF2RB are shown (see all 134 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 96)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs131842^1,2	A,C,F,H,O	35665719(-)	`CCATCC/TGTGAA`	1	--	ut3¹		13	EU EA WA NA	1164
	rs4821568^1,2	A,C,F,H	35646422(+)	`gattaT/Caggga`	1	--	ng5¹ tfbs³		4	EU EA WA	418
--	rs6000495^1,2	A,C,F,H	35664899(+)	`GATGCG/AGCTGG`	1	--	ut3¹		8	EU EA WA	840
	rs5756408^1,2	A,C,F,H	35647794(+)	`GCCCCT/CGTCTC`	1	--	ng5¹		3	EA WA	282
	rs6000496^1,2	A,C,F,H	35665261(+)	`GTGGTG/CGGCAG`	1	--	ut3¹		4	EU EA WA	418
	rs4821567^1,2	A,C,F,H	35646334(+)	`cctaaT/Gcccca`	1	--	ng5¹		4	EU EA WA	418
	rs5756407^1,2	A,C,F,H	35646205(+)	`GAGTAT/CTGTTT`	1	--	ng5¹		11	EU EA WA NA	974
	rs10222238^1,2	C,F,H	35647960(+)	`AACACG/TGGCGG`	1	--	ng5¹		4	EU EA WA	372
	rs4820261^1,2	C,F,H	35646895(+)	`tCATCG/ACTTCA`	1	--	ng5¹ tfbs³		12	EU EA WA NS NA	668
	rs16845^1,2	C,F,H	35656389(+)	`ACCTGG/CAGTGC`	1	Q/E	mis¹		10	MN EU EA WA	904

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HapMap Linkage Disequilibrium images for CSF2RB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 138981

UniProtKB/Swiss-Prot: IL3RB_HUMAN, P32927

Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP)

[MIM:265120]. PAP is an autosomal recessive fatal respiratory disease

1 PharmGKB disease relationship for CSF2RB gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

Human Gene Mutation Database: CSF2RB
Human Genome Epidemiology Navigator: CSF2RB (5 documents)

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/77 PubMed articles for CSF2RB gene (see all 77 ):

An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope. (PubMed id 16754968)^{1, 3, 4} Carr P.D.... Young I.G. (2006)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{3, 4} Collins J.E.... Dunham I. (2004)
Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration. (PubMed id 11207369)^{3, 4} Carr P.D.... Young I.G. (2001)
Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist. (PubMed id 10753826)^{3, 4} Rossjohn J.... Bagley C.J. (2000)
The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony- stimulating factor, interleukin-3 and interleukin-5. (PubMed id 10736232)^{3, 4} Mulhern T.D.... Bagley C.J. (2000)
Human pulmonary alveolar proteinosis associated with a defect in GM- CSF/IL-3/IL-5 receptor common beta chain expression. (PubMed id 9410898)^{3, 4} Dirksen U.... Burdach S. (1997)
Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA) localized to the X-Y pseudoautosomal region. (PubMed id 8213838)^{2, 3} Milatovich A....Francke U. (1993)
Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. (PubMed id 1833064)^{2, 3} Kitamura T.... Miyajima A. (1991)
Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. (PubMed id 1702217)^{3, 4} Hayashida K....Miyajima A. (1990)
Association study of CSF2RB with schizophrenia in Irish family and case - control samples. (PubMed id 17667962)^{1, 3} Chen Q....Chen X. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 1439	HGNC: 2436	AceView: CSF2RB	Ensembl:ENSG00000100368	euGenes: HUgn1439
ECgene: CSF2RB	H-InvDB: CSF2RB

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for CSF2RB	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for CSF2RB
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for CSF2RB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CSF2RB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CSF2RB		Browse antibodies at Sigma-Aldrich
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	Lentivirus-delivered shRNAs for CSF2RB		Browse small molecules at Sigma-Aldrich
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Antibodies for CSF2RB

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CSF2RB Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for CSF2RB

Summaries
for CSF2RB

Genomic Location
for CSF2RB

Proteins
for CSF2RB

Protein Domains/
Families
for CSF2RB

Gene Function
for CSF2RB

Pathways & Interactions
for CSF2RB

Drugs & Compounds
for CSF2RB

Transcripts
for CSF2RB

Expression
for CSF2RB

Orthologs
for CSF2RB

Paralogs
for CSF2RB

SNPs/Variants
for CSF2RB

Disorders & Mutations
for CSF2RB

Medical News
for CSF2RB

Publications
for CSF2RB

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Genome Databases showing CSF2RB

Other Databases showing CSF2RB

Specialized Databases showing CSF2RB

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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CSF2RB Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor CSF2RB

Summariesfor CSF2RB

Genomic Locationfor CSF2RB

Proteinsfor CSF2RB

Protein Domains/Familiesfor CSF2RB

Gene Functionfor CSF2RB

Pathways & Interactionsfor CSF2RB

Drugs & Compoundsfor CSF2RB

Transcriptsfor CSF2RB

Expression for CSF2RB

Orthologsfor CSF2RB

Paralogsfor CSF2RB

SNPs/Variantsfor CSF2RB

Disorders & Mutationsfor CSF2RB

Medical Newsfor CSF2RB

Publicationsfor CSF2RB

Search for CSF2RB

Genome Databases showing CSF2RB

Other Databases showing CSF2RB

Specialized Databases showing CSF2RB

Licensable Technologiesfor CSF2RB

Servicesfor CSF2RB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CSF2RB

Summaries
for CSF2RB

Genomic Location
for CSF2RB

Proteins
for CSF2RB

Protein Domains/
Families
for CSF2RB

Gene Function
for CSF2RB

Pathways & Interactions
for CSF2RB

Drugs & Compounds
for CSF2RB

Transcripts
for CSF2RB

Expression
for CSF2RB

Orthologs
for CSF2RB

Paralogs
for CSF2RB

SNPs/Variants
for CSF2RB

Disorders & Mutations
for CSF2RB

Medical News
for CSF2RB

Publications
for CSF2RB

Licensable Technologies
for CSF2RB

Services
for CSF2RB