Aliases for CSF2 Gene
External Ids for CSF2 Gene
Previous GeneCards Identifiers for CSF2 Gene
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
GeneCards Summary for CSF2 Gene
CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Leukemoid Reaction and Cyclic Thrombocytopenia. Among its related pathways are PEDF Induced Signaling and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding.
UniProtKB/Swiss-Prot for CSF2 Gene
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.