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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CSDE1 Gene

protein-coding   GIFtS: 54
GCID: GC01M115259

cold shock domain containing E1, RNA-binding

 Explore 6 diseases affiliated with
CSDE1 via our new
 Human Malady Compendium 
Biological research products
for CSDE1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cold Shock Domain Containing E1, RNA-Binding1 2     Cold Shock Domain-Containing Protein E12
D1S155E1 2 3 5     Upstream Of NRAS2
UNR1 2 3 5     KIAA08853
N-Ras Upstream Gene Protein2 3     NRU3
NRAS-Related1     Protein UNR3
RP5-1000E10.32     

External Ids:    HGNC: 299051   Entrez Gene: 78122   Ensembl: ENSG000000093077   OMIM: 1915105   UniProtKB: O755343   

Export aliases for CSDE1 gene to outside databases

Previous GC identifers: GC01M114972 GC01M115049 GC01M113117


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CSDE1_HUMAN, O75534
Function: RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved
in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic
deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of
instability (mCRD) domain

Gene Wiki entry for CSDE1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CSDE1 gene promoter:
         FOXC1   NRSF form 1   NRSF form 2   Pax-4a   Gfi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCSDE1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CSDE1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSDE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22   Ensembl cytogenetic band:  1p13.2   HGNC cytogenetic band: 1p13.2

CSDE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CSDE1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M115259:  view genomic region     (about GC identifiers)

Start:
115,259,534 bp from pter      End:
115,301,297 bp from pter
Size:
41,764 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CSDE1_HUMAN, O75534 (See protein sequence)
Recommended Name: Cold shock domain-containing protein E1  
Size: 798 amino acids; 88885 Da
Subunit: Component of a multi subunit autoregulatory ribonucleoprotein complex (ARC), at least composed of IGF2BP1,
PABPC1 and CSDE1. Interacts with STRAP. Part of a complex associated with the FOS mCRD domain and consisting of
PABPC1, PAIP1, HNRPD and SYNCRIP. The interaction with PABPC1 is direct and RNA-independent
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAA74908.2; Type=Erroneous initiation; Sequence=CAH18231.1; Type=Erroneous initiation;
5 PDB 3D structures from and Proteopedia for CSDE1:
1WFQ (3D)        1X65 (3D)        2YTV (3D)        2YTX (3D)        2YTY (3D)    
Secondary accessions: A8K281 E9PGZ0 O94961 Q5TF04 Q5TF05 Q68DF1 Q68DI9 Q9Y2S4
Alternative splicing: 3 isoforms:  O75534-1   O75534-2   O75534-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CSDE1: NX_O75534

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75534

  • CSDE1 Protein expression data from MOPED and PaxDb:    About this image 
    CSDE1 Protein Expression
    REFSEQ proteins (6 alternative transcripts): 
    NP_001007554.1  NP_001123995.1  NP_001229820.1  NP_001229821.1  NP_001229822.1  NP_009089.4  

    ENSEMBL proteins: 
     ENSP00000342408   ENSP00000407724   ENSP00000351329   ENSP00000261443   ENSP00000431297  
     ENSP00000358543   ENSP00000432958   ENSP00000437159   ENSP00000431770   ENSP00000435185  
     ENSP00000431562   ENSP00000432805  

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    Novus Biologicals CSDE1 Proteins
    Novus Biologicals CSDE1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CSDE1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005743mitochondrial inner membrane ----

    CSDE1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CSDE1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CSDE1 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR024642 SUZ-C
     IPR019844 Cold-shock_CS
     IPR012340 NA-bd_OB-fold
     IPR011129 Cold_shock_prot
     IPR002059 CSP_DNA-bd

    Graphical View of Domain Structure for InterPro Entry O75534

    ProtoNet protein and cluster: O75534

    2 Blocks protein families:
    IPB002059 Cold-shock DNA-binding domain
    IPB011129 Cold shock protein


    UniProtKB/Swiss-Prot: CSDE1_HUMAN, O75534
    Similarity: Contains 9 CSD (cold-shock) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CSDE1_HUMAN, O75534
    Function: RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved
    in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic
    deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of
    instability (mCRD) domain

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003723RNA binding IEA--
         
    CSDE1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CSDE1 

    miRNA
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    hsa-miR-582-3p hsa-miR-15a hsa-miR-519a hsa-miR-218 hsa-miR-502-3p hsa-miR-424 hsa-miR-124 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidCSDE1 3' UTR sequence
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSDE1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Validated targets of C-MYC transcriptional repression
    Validated targets of C-MYC transcriptional repression1.00


    1 BioSystems Pathway for CSDE1 
        Validated targets of C-MYC transcriptional repression


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CSDE1

    5/21 Interacting proteins for CSDE1 (O755343) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STT3AP469773I2D: score=4 
    LOH12CR1Q969J33I2D: score=3 
    WNK1Q9H4A33I2D: score=3 
    CDC42P609533I2D: score=2 
    DENRO435833I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0008584male gonad development TAS2204029

    CSDE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CSDE1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CSDE1
    1 Novoseek chemical compound relationship for CSDE1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenylate 24.9 3 15314026 (2)

    Search CenterWatch for drugs/clinical trials and news about CSDE1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CSDE1 gene (6 alternative transcripts): 
    NM_001007553.2  NM_001130523.2  NM_001242891.1  NM_001242892.1  NM_001242893.1  NM_007158.5  

    Unigene Cluster for CSDE1:

    Cold shock domain containing E1, RNA-binding
    Hs.69855  [show with all ESTs]
    Unigene Representative Sequence: NM_001242891
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000339438(uc001efj.3 uc001efl.3 uc001efn.3) ENST00000438362(uc001efi.3 uc001efm.3)
    ENST00000358528(uc001efk.3 uc009wgv.3) ENST00000261443 ENST00000530886
    ENST00000369530 ENST00000483407 ENST00000534699 ENST00000483030 ENST00000530784
    ENST00000529046 ENST00000525132 ENST00000534389 ENST00000525878 ENST00000525970
    ENST00000533818 ENST00000524652

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CSDE1
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate CSDE1 (see all 41):
    hsa-miR-582-3p hsa-miR-15a hsa-miR-519a hsa-miR-218 hsa-miR-502-3p hsa-miR-424 hsa-miR-124 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidCSDE1 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSDE1 (see all 7)
    OriGene shRNA RFP: CSDE1
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    Sirion Biotech Custom design and validation of potent shRNA sequences against CSDE1 
    Clone
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    Additional cDNA sequence: 

    AB020692.1 AF070542.1 AF077054.1 AK022516.1 AK022528.1 AK130392.1 AK290146.1 AL050150.1 
    AL110192.1 AY049788.1 BC017662.1 BC021692.1 BC032446.1 BX648561.1 BX648780.1 CR749378.1 
    CR749431.1 

    24/69 DOTS entries (see all 69):

    DT.92474308  DT.100693473  DT.92474348  DT.100766644  DT.92378501  DT.95101494  DT.92474344  DT.121460021 
    DT.100693459  DT.97818910  DT.100693465  DT.121460068  DT.121459963  DT.95124940  DT.121460114  DT.95200028 
    DT.100693483  DT.102839209  DT.100041872  DT.100855923  DT.121460122  DT.100693460  DT.100693485  DT.121459921 

    24/1776 AceView cDNA sequences (see all 1776):

    BM801160 BQ421587 AI207185 BX421385 AA780939 BQ434011 BG778279 AA358281 
    AA535385 CA391099 CA430492 AI436399 CR615916 BQ051116 BQ717950 BU162266 
    BP343792 BE814147 AI889950 AL042033 BE891445 AU280686 AW675792 CB128834 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for CSDE1 (see all 15)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b · 14c ^ 15 ^ 16 ^
    SP1:                                                  -     -                                                                                                   
    SP2:                                                  -                                   -     -                                                               
    SP3:                                                  -     -                             -     -                                                               
    SP4:              -     -           -     -           -     -                             -     -                                                               
    SP5:              -     -     -     -     -     -     -     -                             -     -                                                               

    ExUns: 17 ^ 18a · 18b ^ 19a · 19b ^ 20 ^ 21a · 21b · 21c ^ 22a · 22b · 22c ^ 23 ^ 24 ^ 25a · 25b · 25c
    SP1:                                      -                             -                                 
    SP2:                                      -                             -                                 
    SP3:                                      -                             -                                 
    SP4:                                                                                                      
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for CSDE1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CSDE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAAATGAGGA
    CSDE1 Expression
    About this image
    See CSDE1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CSDE1

    SOURCE GeneReport for Unigene cluster: Hs.69855
        SABiosciences Expression via Pathway-Focused PCR Array including CSDE1: 

              Nitric Oxide Signaling Pathway in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CSDE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CSDE1 gene from 6/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Csde11 , 5 cold shock domain containing E1, RNA binding1, 5 94.57(n)1
    98.5(a)1
      3 (45.25 cM)5
    2296631  NM_144901.31  NP_659150.11 
     1030205465 
    chicken
    (Gallus gallus)
    Aves CSDE11 cold shock domain containing E1, RNA-binding 85.38(n)
    92.44(a)
      419886  NM_001030918.1  NP_001026089.1 
    lizard
    (Anolis carolinensis)
    Reptilia CSDE16
    --
    91(a)
    1 ↔ 1
    4(130396422-130420115)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.46772 Xenopus laevis clone S10-34-A4 mRNA sequence 75.25(n)    AF549970.1 
    zebrafish
    (Danio rerio)
    Actinopterygii csde11 cold shock domain containing E1, RNA-binding 71.45(n)
    78.49(a)
      337096  XM_002663095.2  XP_002663141.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Unr1 Upstream of N-ras 52.97(n)
    50.56(a)
      38963  NM_001144440.2  NP_001137912.1 


    ENSEMBL Gene Tree for CSDE1 (if available)
    TreeFam Gene Tree for CSDE1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/657 NCBI SNPs in CSDE1 are shown (see all 657    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1493908151,2
    --115261668(+) TAGCTA/GACACC 6 -- int10--------
    rs772548241,2
    F--115261750(+) CAAAAC/GAGTGG 6 -- int11Minor allele frequency- G:0.05WA 118
    rs1463957801,2
    --115261799(+) GTGGCA/GCATGC 6 -- int10--------
    rs1850171741,2
    --115261833(+) GCTGAC/TGTGGG 6 -- int10--------
    rs1891393751,2
    --115261858(+) CCAGGG/TGGTTG 6 -- int10--------
    rs1397525771,2
    --115261898(+) GTAACC/TGAATC 6 -- int10--------
    rs1432144281,2
    --115262076(+) AAGTAG/TGAAGT 6 -- int10--------
    rs120668181,2
    C,H--115262122(+) GAAAAG/ATGATG 6 -- int14Minor allele frequency- A:0.00NS EA 410
    rs726878761,2
    C,F--115262124(+) AAAGTG/AATGTG 6 -- int16Minor allele frequency- A:0.12WA NA CSA EA 364
    rs1483939681,2
    C--115262226(+) GCGCTA/GCACTT 12 C syn10--------

    HapMap Linkage Disequilibrium report for CSDE1 (115259534 - 115301297 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for CSDE1
         3 CNVs: 2322 3306 64651
    Human Gene Mutation Database (HGMD): CSDE1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSDE1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CSDE1 for disorders           About GeneDecksing

    OMIM gene information: 191510    OMIM disorders: --

    6 diseases for CSDE1:    About MalaCards
    diamond-blackfan anemia    chronic lymphocytic leukemia    lymphocytic leukemia    leukemia
    breast cancer    anemia

    1 Novoseek disease relationship for CSDE1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 18.8 5 7518919 (2), 8934551 (1), 10101203 (1)

    Human Genome Epidemiology (HuGE) Navigator: CSDE1 (6 documents)

    Export disorders for CSDE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CSDE1 gene, integrated from 9 sources (see all 68):
    (articles sorted by number of sources associating them with CSDE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T....Ohara O. (1998)
    2. Characterization of unr; a gene closely linked to N-ras. (PubMed id 2204029)1, 3, 9 Jeffers M....Pellicer A. (1990)
    3. UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. (PubMed id 15314026)1, 2, 9 Chang T.-C.... Shyu A.-B. (2004)
    4. Exon skipping in the expression of the gene immediately upstream of N-ras (unr/NRU). (PubMed id 8439573)1, 2, 9 Boussadia O.... Dautry F. (1993)
    5. unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. (PubMed id 10049359)1, 2, 9 Hunt S.L.... Jackson R.J. (1999)
    6. A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex. (PubMed id 11051545)1, 2, 9 Grosset C....Shyu A.-B. (2000)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    9. The autoregulatory translational control element of poly(A)-binding protein mRNA forms a heteromeric ribonucleoprotein complex. (PubMed id 16356927)1, 2 Patel G.P.... Bag J. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7812 HGNC: 29905 AceView: NRASandUNR Ensembl:ENSG00000009307 euGenes: HUgn7812
    ECgene: CSDE1 H-InvDB: CSDE1

    (According to HUGE)
    About This Section
    HUGE: KIAA0885

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CSDE1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CSDE1 gene:
    Search GeneIP for patents involving CSDE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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