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Aliases for CSAG3 Gene

Aliases for CSAG3 Gene

  • CSAG Family Member 3 2 5
  • Taxol-Resistant-Associated Gene 3 Protein 3 4
  • Cancer/Testis Antigen 24.2 3 4
  • CSAG Family, Member 3A 2 3
  • CSAG Family, Member 3 2 3
  • CT24.2 3 4
  • CSAG3A 3 4
  • Taxol Resistance Associated Gene 3 3
  • CSAG2 CSAG3 4
  • TRAG-3 4
  • TRAG3 4

External Ids for CSAG3 Gene

Previous HGNC Symbols for CSAG3 Gene

  • CSAG3A

Previous GeneCards Identifiers for CSAG3 Gene

  • GC0XM151630
  • GC0XM151876
  • GC0XP140729

Summaries for CSAG3 Gene

GeneCards Summary for CSAG3 Gene

CSAG3 (CSAG Family Member 3) is a Protein Coding gene. Diseases associated with CSAG3 include chondrosarcoma. An important paralog of this gene is CSAG2.

UniProtKB/Swiss-Prot for CSAG3 Gene

  • Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CSAG3 Gene

Genomics for CSAG3 Gene

Regulatory Elements for CSAG3 Gene


Genomic Location for CSAG3 Gene

Chromosome:
X
Start:
152,753,921 bp from pter
End:
152,760,222 bp from pter
Size:
6,302 bases
Orientation:
Plus strand

Genomic View for CSAG3 Gene

Genes around CSAG3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CSAG3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CSAG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CSAG3 Gene

Proteins for CSAG3 Gene

  • Protein details for CSAG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y5P2-CSAG2_HUMAN
    Recommended name:
    Chondrosarcoma-associated gene 2/3 protein
    Protein Accession:
    Q9Y5P2
    Secondary Accessions:
    • O75605
    • Q0VDC3
    • Q96IU8

    Protein attributes for CSAG3 Gene

    Size:
    127 amino acids
    Molecular mass:
    14430 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CSAG3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CSAG3 Gene

Proteomics data for CSAG3 Gene at MOPED

Post-translational modifications for CSAG3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CSAG3 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for CSAG3 Gene

Domains & Families for CSAG3 Gene

Protein Domains for CSAG3 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CSAG3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CSAG3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CSAG3 Gene

Function for CSAG3 Gene

Molecular function for CSAG3 Gene

UniProtKB/Swiss-Prot Function:
Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.

Phenotypes for CSAG3 Gene

GenomeRNAi human phenotypes for CSAG3:
genes like me logo Genes that share phenotypes with CSAG3: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CSAG3 Gene

Localization for CSAG3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CSAG3 Gene

Pathways & Interactions for CSAG3 Gene

SuperPathways for CSAG3 Gene

No Data Available

Interacting Proteins for CSAG3 Gene

Gene Ontology (GO) - Biological Process for CSAG3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CSAG3 Gene

Drugs & Compounds for CSAG3 Gene

No Compound Related Data Available

Transcripts for CSAG3 Gene

mRNA/cDNA for CSAG3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CSAG3 Gene

No ASD Table

Relevant External Links for CSAG3 Gene

GeneLoc Exon Structure for
CSAG3
ECgene alternative splicing isoforms for
CSAG3

Expression for CSAG3 Gene

mRNA expression in normal human tissues for CSAG3 Gene

mRNA Expression by UniProt/SwissProt for CSAG3 Gene

Q9Y5P2-CSAG2_HUMAN
Tissue specificity: Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435TR and the doxorubicin-resistant multiple myelanoma lines RPMI-8226/Dox40 and RPMI-8226/MDR10V.
genes like me logo Genes that share expression patterns with CSAG3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for CSAG3 Gene

Orthologs for CSAG3 Gene

Evolution for CSAG3 Gene

ENSEMBL:
Gene Tree for CSAG3 (if available)
TreeFam:
Gene Tree for CSAG3 (if available)

No data available for Orthologs for CSAG3 Gene

Paralogs for CSAG3 Gene

Paralogs for CSAG3 Gene

(1) SIMAP similar genes for CSAG3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CSAG3: view

Variants for CSAG3 Gene

Sequence variations from dbSNP and Humsavar for CSAG3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs5742340 -- 152,758,839(+) tttct(C/T)tctct intron-variant, upstream-variant-2KB
rs5970380 -- 152,759,840(+) CCTTC(C/T)AGGTT intron-variant
rs62610452 -- 152,758,835(-) AGAGA(A/G)AGAGA intron-variant, upstream-variant-2KB
rs782524329 -- 152,757,640(+) AATGG(-/AT)ATATA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CSAG3 Gene

Variant ID Type Subtype PubMed ID
dgv2493e1 CNV Complex 17122850

Relevant External Links for CSAG3 Gene

HapMap Linkage Disequilibrium report
CSAG3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CSAG3 Gene

Disorders for CSAG3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CSAG3 Gene - From: GeneCards

Disorder Aliases PubMed IDs
chondrosarcoma
  • chondrosarcoma of bone
- elite association - COSMIC cancer census association via MalaCards
Search CSAG3 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CSAG3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CSAG3
genes like me logo Genes that share disorders with CSAG3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CSAG3 Gene

Publications for CSAG3 Gene

  1. TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line. (PMID: 10095106) Duan Z. … Seiden M.V. (Gene 1999) 3 4 67
  2. Human tumor antigen-specific helper and regulatory T cells share common epitope specificity but exhibit distinct T cell repertoire. (PMID: 20483736) Fourcade J. … Zarour H.M. (J. Immunol. 2010) 3
  3. Coordinated expression of clustered cancer/testis genes encoded in a large inverted repeat DNA structure. (PMID: 18395366) Bredenbeck A. … Losch F.O. (Gene 2008) 3
  4. Taxol-resistance-associated gene-3 (TRAG-3/CSAG2) expression is predictive for clinical outcome in ovarian carcinoma patients. (PMID: 17216190) Materna V. … Lage H. (Virchows Arch. 2007) 3
  5. Expression of the TRAG-3 gene in human esophageal cancer: the frequent synchronous expression of MAGE-3 gene. (PMID: 16685391) Ohta M. … Mori M. (Oncol. Rep. 2006) 3

Products for CSAG3 Gene

Sources for CSAG3 Gene

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