CSAG1 Gene
protein-coding GIFtS: 38
GCID: GC0XP151903
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chondrosarcoma associated gene 1
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Aliases
for CSAG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chondrosarcoma Associated Gene 11 2 | | Cancer/Testis Antigen CSAGE2 3 | | CSAGE1 2 3 | | Cancer/Testis Antigen Family 24, Member 12 | | CT24.11 2 3 | | Putative Chondrosarcoma-Associated Gene 1 Protein2 | | Cancer/Testis Antigen 24.12 3 | | |
Export aliases for CSAG1 gene to outside databasesPrevious GC identifers: GC0XP151573 GC0XP151653 GC0XP140705 |
Summaries
for CSAG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CSAG1:
This gene encodes a member of a family of tumor antigens. The protein is expressed in chondrosarcomas, but may also beexpressed in normal tissues such as testis. Alternative splicing of this gene results in two transcript variantsencoding the same protein. (provided by RefSeq, Jul 2008)
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Genomic Views
for CSAG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167198.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CSAG1 gene promoter:
TBP HNF-1A POU2F1 FOXJ2 (long isoform) TFIID HNF-1 POU2F1a FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CSAG1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSAG1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28CSAG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP151903: view genomic region
(about GC identifiers)
Start:
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151,903,228 bp from pter |
End:
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151,909,518 bp from pter |
Size:
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6,291 bases |
Orientation:
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plus strand |
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Proteins
for CSAG1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CSAG1_HUMAN, Q6PB30 (See
protein sequence)Recommended Name: Putative chondrosarcoma-associated gene 1 protein precursor Size: 78 amino acids; 8669 Da
Secondary accessions: A6NE22Alternative splicing: 2 isoforms: Q6PB30-1 Q6PB30-2 Explore the universe of human proteins at neXtProt for CSAG1: NX_Q6PB30
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6PB30
CSAG1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001096046.1 NP_705611.1
ENSEMBL proteins: ENSP00000359310 ENSP00000396520 ENSP00000354898 ENSP00000359314
Human Recombinant Protein Products for CSAG1:
CSAG1 Antibody Products:
Assay Products for CSAG1: |
Protein
Domains /
Families
for CSAG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6PB30 |
Function
for CSAG1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for CSAG1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CSAG1 (NM_001102576) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CSAG1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSAG1 |
|
Pathways & Interactions
for CSAG1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CSAG1
|
Drugs & Compounds
for CSAG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CSAG1
Search CenterWatch for drugs/clinical trials and news about CSAG1
|
Transcripts
for CSAG1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CSAG1 gene (3 alternative transcripts): NM_001102576.1 NM_153478.1 NM_153479.1 Unigene Cluster for CSAG1: Chondrosarcoma associated gene 1 Hs.423718 [show with all ESTs]Unigene Representative Sequence: CA4552614 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370287(uc004fge.3 uc004fgf.3 uc004fgd.3) ENST00000452779
ENST00000361211 ENST00000370291
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CSAG1 (NM_001102576) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CSAG1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSAG1 |
Additional cDNA sequence: AF195880.1 AF268418.1 BC059947.1 3 DOTS entries: DT.95271761 DT.100754649 DT.95271758 14 AceView cDNA sequences: NM_153478 BM810082 BQ681208 BC059947 BI859613 BI859027 BG189235 AF195880 BG188186 BI858553 BG193951 BG212104 BF570999 BQ277563
GeneLoc Exon Structure
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Expression
for CSAG1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CSAG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGTAAAAAA
About this image
See CSAG1 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.423718
UniProtKB/Swiss-Prot: CSAG1_HUMAN, Q6PB30Tissue specificity: Expressed in chondrosarcoma, melanoma, cartilage and testis, but not in other normal tissues
SABiosciences Custom PCR Arrays for CSAG1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSAG1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CSAG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSAG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSAG1 |
Orthologs
for CSAG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
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ENSEMBL Gene Tree for CSAG1 (if available)
TreeFam Gene Tree for CSAG1 (if available) |
Paralogs
for CSAG1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CSAG1 gene
2 SIMAP similar genes for CSAG1 using alignment to 2 protein entries: CSAG1_HUMAN (see all proteins):CSAG2 CSAG3
CSAG1 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for CSAG1
PGOHUM00000258435 PGOHUM00000241603 PGOHUM00000258444
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Genomic Variants
for CSAG1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CSAG1 (151903228 - 151909518 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CSAG1
1 CNV: 3273
Human Gene Mutation Database (HGMD): CSAG1
Locus Specific Mutation Databases (LSDB): CSAG1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSAG1 |
|
Disorders
/ Diseases
for CSAG1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CSAG1 for disorders About GeneDecksing
2  diseases for CSAG1: About MalaCardschondrosarcoma melanoma
Export disorders for CSAG1 gene to outside databases
|
Publications
for CSAG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CSAG1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CSAG1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cancer/testis antigen CSAGE is concurrently expressed with MAGE in chondrosarcoma. (PubMed id 12039054)1, 2, 3 Lin C....Terek R.M. (2002)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for CSAG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CSAG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CSAG1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CSAG1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CSAG1 gene:
Search GeneIP for patents involving CSAG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CSAG1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CSAG1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CSAG1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CSAG1 | | | OriGene Protein Over-expression Lysate for CSAG1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CSAG1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CSAG1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CSAG1 | | OriGene Custom Protein Services for CSAG1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CSAG1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CSAG1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CSAG1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CSAG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CSAG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CSAG1 |
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 | | | CSAG1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for CSAG1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CSAG1 |
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