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Aliases for CSAG1 Gene

Aliases for CSAG1 Gene

  • Chondrosarcoma Associated Gene 1 2 3 5
  • Cancer/Testis Antigen Family 24, Member 1 2 3
  • Cancer/Testis Antigen CSAGE 3 4
  • Cancer/Testis Antigen 24.1 3 4
  • CT24.1 3 4
  • CSAGE 3 4
  • Putative Chondrosarcoma-Associated Gene 1 Protein 3

External Ids for CSAG1 Gene

Previous GeneCards Identifiers for CSAG1 Gene

  • GC0XP151573
  • GC0XP151653
  • GC0XP151903
  • GC0XP140705

Summaries for CSAG1 Gene

Entrez Gene Summary for CSAG1 Gene

  • This gene encodes a member of a family of tumor antigens. The protein is expressed in chondrosarcomas, but may also be expressed in normal tissues such as testis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for CSAG1 Gene

CSAG1 (Chondrosarcoma Associated Gene 1) is a Protein Coding gene. Diseases associated with CSAG1 include Chondrosarcoma. An important paralog of this gene is CSAG2.

Additional gene information for CSAG1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CSAG1 Gene

Genomics for CSAG1 Gene

Regulatory Elements for CSAG1 Gene

Genomic Locations for CSAG1 Gene

Genomic Locations for CSAG1 Gene
6,253 bases
Minus strand

Genomic View for CSAG1 Gene

Genes around CSAG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CSAG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CSAG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CSAG1 Gene

Proteins for CSAG1 Gene

  • Protein details for CSAG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative chondrosarcoma-associated gene 1 protein
    Protein Accession:
    Secondary Accessions:
    • A6NE22

    Protein attributes for CSAG1 Gene

    78 amino acids
    Molecular mass:
    8669 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CSAG1 Gene


neXtProt entry for CSAG1 Gene

Post-translational modifications for CSAG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CSAG1 Gene

No data available for DME Specific Peptides for CSAG1 Gene

Domains & Families for CSAG1 Gene

Gene Families for CSAG1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CSAG1 Gene


Suggested Antigen Peptide Sequences for CSAG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CSAG1: view

No data available for UniProtKB/Swiss-Prot for CSAG1 Gene

Function for CSAG1 Gene

genes like me logo Genes that share phenotypes with CSAG1: view

Animal Model Products

CRISPR Products

miRNA for CSAG1 Gene

miRTarBase miRNAs that target CSAG1

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CSAG1 Gene

Localization for CSAG1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CSAG1 gene
Compartment Confidence
nucleus 3
extracellular 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CSAG1 Gene

Pathways & Interactions for CSAG1 Gene

SuperPathways for CSAG1 Gene

No Data Available

Interacting Proteins for CSAG1 Gene

Gene Ontology (GO) - Biological Process for CSAG1 Gene


No data available for Pathways by source and SIGNOR curated interactions for CSAG1 Gene

Drugs & Compounds for CSAG1 Gene

No Compound Related Data Available

Transcripts for CSAG1 Gene

mRNA/cDNA for CSAG1 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CSAG1 Gene

Chondrosarcoma associated gene 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for CSAG1 Gene

No ASD Table

Relevant External Links for CSAG1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CSAG1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CSAG1 Gene

mRNA differential expression in normal tissues according to GTEx for CSAG1 Gene

This gene is overexpressed in Brain - Caudate (basal ganglia) (x5.1), Brain - Putamen (basal ganglia) (x5.1), Testis (x5.0), Brain - Frontal Cortex (BA9) (x4.6), Brain - Anterior cingulate cortex (BA24) (x4.6), Brain - Hippocampus (x4.1), and Brain - Substantia nigra (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of CSAG1 Gene:


SOURCE GeneReport for Unigene cluster for CSAG1 Gene:


mRNA Expression by UniProt/SwissProt for CSAG1 Gene:

Tissue specificity: Expressed in chondrosarcoma, melanoma, cartilage and testis, but not in other normal tissues.
genes like me logo Genes that share expression patterns with CSAG1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CSAG1 Gene

Orthologs for CSAG1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CSAG1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CSAG1 34
  • 90 (a)
Species where no ortholog for CSAG1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CSAG1 Gene

Gene Tree for CSAG1 (if available)
Gene Tree for CSAG1 (if available)

Paralogs for CSAG1 Gene

Paralogs for CSAG1 Gene

(2) SIMAP similar genes for CSAG1 Gene using alignment to 2 proteins: Pseudogenes for CSAG1 Gene

genes like me logo Genes that share paralogs with CSAG1: view

Variants for CSAG1 Gene

Sequence variations from dbSNP and Humsavar for CSAG1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111942589 -- 152,733,616(-) GGATC(A/C)TGAGG intron-variant, upstream-variant-2KB
rs111946653 -- 152,732,998(-) TATTT(C/G)TACGA intron-variant, upstream-variant-2KB
rs112028367 -- 152,727,322(-) GATTT(C/T)ATTTT downstream-variant-500B
rs112142853 -- 152,732,819(-) ACCCA(A/G)TTTTC intron-variant, upstream-variant-2KB
rs112210250 -- 152,734,522(-) ATTCC(C/T)GCGGC intron-variant, upstream-variant-2KB

Variation tolerance for CSAG1 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.31; 70.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CSAG1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CSAG1 Gene

Disorders for CSAG1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CSAG1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
  • chondrosarcoma of bone
- elite association - COSMIC cancer census association via MalaCards
Search CSAG1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CSAG1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CSAG1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CSAG1 Gene

Publications for CSAG1 Gene

  1. Cancer/testis antigen CSAGE is concurrently expressed with MAGE in chondrosarcoma. (PMID: 12039054) Lin C … Terek RM (Gene 2002) 2 3 4 60
  2. Analysis of compensatory substitution and gene evolution on the MAGEA/CSAG-palindrome of the primate X chromosomes. (PMID: 23257410) Qi Y … Ai D (Computational biology and chemistry 2013) 3 60
  3. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M … Gstaiger M (Cell reports 2013) 3 60
  4. Exome sequencing in a family segregating for celiac disease. (PMID: 21627641) Szperl AM … Zheng HC (Clinical genetics 2011) 3 60
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 60

Products for CSAG1 Gene

Sources for CSAG1 Gene

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