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Aliases for CSAG1 Gene

Aliases for CSAG1 Gene

  • Chondrosarcoma Associated Gene 1 2 3
  • Cancer/Testis Antigen CSAGE 3 4
  • Cancer/Testis Antigen 24.1 3 4
  • CT24.1 3 4
  • CSAGE 3 4
  • Putative Chondrosarcoma-Associated Gene 1 Protein 3
  • Cancer/Testis Antigen Family 24, Member 1 3
  • Cancer/Testis Antigen Family 24 2
  • Member 1 2

External Ids for CSAG1 Gene

Summaries for CSAG1 Gene

Entrez Gene Summary for CSAG1 Gene

  • This gene encodes a member of a family of tumor antigens. The protein is expressed in chondrosarcomas, but may also be expressed in normal tissues such as testis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for CSAG1 Gene

CSAG1 (Chondrosarcoma Associated Gene 1) is a Protein Coding gene. Diseases associated with CSAG1 include chondrosarcoma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CSAG1 Gene

Genomics for CSAG1 Gene

Genomic Location for CSAG1 Gene

Start:
152,727,484 bp from pter
End:
152,733,735 bp from pter
Size:
6,252 bases
Orientation:
Minus strand

Genomic View for CSAG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CSAG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CSAG1 Gene

Regulatory Elements for CSAG1 Gene

Proteins for CSAG1 Gene

  • Protein details for CSAG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PB30-CSAG1_HUMAN
    Recommended name:
    Putative chondrosarcoma-associated gene 1 protein
    Protein Accession:
    Q6PB30
    Secondary Accessions:
    • A6NE22

    Protein attributes for CSAG1 Gene

    Size:
    78 amino acids
    Molecular mass:
    8669 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CSAG1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CSAG1 Gene

Proteomics data for CSAG1 Gene at MOPED

Post-translational modifications for CSAG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CSAG1 Gene

No data available for DME Specific Peptides for CSAG1 Gene

Domains for CSAG1 Gene

Protein Domains for CSAG1 Gene

ProtoNet:
genes like me logo Genes that share domains with CSAG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CSAG1 Gene

Function for CSAG1 Gene

Phenotypes for CSAG1 Gene

GenomeRNAi human phenotypes for CSAG1:
genes like me logo Genes that share phenotypes with CSAG1: view

miRNA for CSAG1 Gene

miRTarBase miRNAs that target CSAG1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for CSAG1 Gene

Localization for CSAG1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CSAG1 Gene COMPARTMENTS Subcellular localization image for CSAG1 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for CSAG1 Gene

Pathways for CSAG1 Gene

SuperPathways for CSAG1 Gene

No Data Available

Interacting Proteins for CSAG1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359310%0d%0a9606.ENSP00000377262%0d%0a9606.ENSP00000362931%0d%0a
Selected Interacting proteins: ENSP00000359310 for CSAG1 Gene via STRING

Gene Ontology (GO) - Biological Process for CSAG1 Gene

None

No data available for Pathways by source for CSAG1 Gene

Transcripts for CSAG1 Gene

mRNA/cDNA for CSAG1 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CSAG1 Gene

Chondrosarcoma associated gene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CSAG1 Gene

No ASD Table

Relevant External Links for CSAG1 Gene

GeneLoc Exon Structure for
CSAG1
ECgene alternative splicing isoforms for
CSAG1

Expression for CSAG1 Gene

mRNA expression in normal human tissues for CSAG1 Gene

mRNA differential expression in normal tissues according to GTEx for CSAG1 Gene

This gene is overexpressed in Brain - Caudate (basal ganglia) (5.1), Brain - Putamen (basal ganglia) (5.1), Testis (5.0), Brain - Frontal Cortex (BA9) (4.6), Brain - Anterior cingulate cortex (BA24) (4.6), Brain - Hippocampus (4.1), and Brain - Substantia nigra (4.1).

SOURCE GeneReport for Unigene cluster for CSAG1 Gene Hs.423718

mRNA Expression by UniProt/SwissProt for CSAG1 Gene

Q6PB30-CSAG1_HUMAN
Tissue specificity: Expressed in chondrosarcoma, melanoma, cartilage and testis, but not in other normal tissues.
genes like me logo Genes that share expressions with CSAG1: view

Orthologs for CSAG1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CSAG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CSAG1 37
  • 90 (a)
OneToOne
Species with no ortholog for CSAG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CSAG1 Gene

ENSEMBL:
Gene Tree for CSAG1 (if available)
TreeFam:
Gene Tree for CSAG1 (if available)

Paralogs for CSAG1 Gene

Selected SIMAP similar genes for CSAG1 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for CSAG1 Gene

genes like me logo Genes that share paralogs with CSAG1: view

No data available for Paralogs for CSAG1 Gene

Variants for CSAG1 Gene

Sequence variations from dbSNP and Humsavar for CSAG1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1974444 -- 152,731,141(-) ACACT(C/T)GCCTA intron-variant
rs2471783 -- 152,730,659(-) agact(A/G)ggtgg intron-variant
rs2471784 -- 152,730,438(-) catga(A/T)ctagt intron-variant
rs2471785 -- 152,729,038(-) AATCT(A/G)TGTGT intron-variant
rs2471786 -- 152,728,527(-) TAAGA(C/T)TGCGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CSAG1 Gene

Variant ID Type Subtype PubMed ID
dgv2493e1 CNV Complex 17122850

Relevant External Links for CSAG1 Gene

HapMap Linkage Disequilibrium report
CSAG1
Locus Specific Mutation Databases (LSDB)
CSAG1

Disorders for CSAG1 Gene

(1) MalaCards Diseases for CSAG1 Gene

Search for CSAG1 Gene in MalaCards »
genes like me logo Genes that share disorders with CSAG1: view

No data available for UniProtKB/Swiss-Prot for CSAG1 Gene

Publications for CSAG1 Gene

  1. Cancer/testis antigen CSAGE is concurrently expressed with MAGE in chondrosarcoma. (PMID: 12039054) Lin C. … Terek R.M. (Gene 2002) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family. (PMID: 17342728) Hansen M.A. … Leffers H. (Mol. Reprod. Dev. 2008) 3
  5. Exome sequencing in a family segregating for celiac disease. (PMID: 21627641) Szperl A.M. … Zheng H.C. (Clin. Genet. 2011) 3

Products for CSAG1 Gene

Sources for CSAG1 Gene

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