External Ids for CS Gene
Previous GeneCards Identifiers for CS Gene
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008]
GeneCards Summary for CS Gene
CS (Citrate Synthase) is a Protein Coding gene. Diseases associated with CS include critical illness polyneuropathy and mitochondrial cardiomyopathy. Among its related pathways are Metabolism and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include citrate (Si)-synthase activity.