Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CRYGA Gene

protein-coding   GIFtS: 50
GCID: GC02M209025

Crystallin, Gamma A


(Previous symbol: CRYG1)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Crystallin, Gamma A1 2     CRYG52
CRYG11 2 3 5     Crystallin, Gamma 12
Gamma-Crystallin 52 3     Gamma-Crystallin A2
Gamma Crystallin 51     Gamma-A-crystallin3
CRY-g-A2     

External Ids:    HGNC: 24081   Entrez Gene: 14182   Ensembl: ENSG000001685827   OMIM: 1236605   UniProtKB: P118443   

Export aliases for CRYGA gene to outside databases

Previous GC identifers: GC02M207194 GC02M207750 GC02M208989 GC02M209228 GC02M208850 GC02M208733 GC02M200873


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CRYGA Gene:
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class
constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the
lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then
retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into
alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta
families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four
homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous
group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions.
They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D)
and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster.
Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
(provided by RefSeq, Jul 2008)

GeneCards Summary for CRYGA Gene:
CRYGA (crystallin, gamma A) is a protein-coding gene. GO annotations related to this gene include structural constituent of eye lens. An important paralog of this gene is CRYBB3.

UniProtKB/Swiss-Prot: CRGA_HUMAN, P11844
Function: Crystallins are the dominant structural components of the vertebrate eye lens

Gene Wiki entry for CRYGA Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CRYGA gene promoter:
         SRF   NCX/Ncx   SRF (504 AA)   HTF   MIF-1   LCR-F1   AREB6   PPAR-gamma1   c-Myb   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCRYGA promoter sequence
   Search Chromatin IP Primers for CRYGA

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRYGA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q34   Ensembl cytogenetic band:  2q34   HGNC cytogenetic band: 2q34

CRYGA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRYGA gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M209025:  view genomic region     (about GC identifiers)

Start:
209,025,464 bp from pter      End:
209,028,300 bp from pter
Size:
2,837 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CRGA_HUMAN, P11844 (See protein sequence)
Recommended Name: Gamma-crystallin A  
Size: 174 amino acids; 20877 Da
Subunit: Monomer (By similarity)
1 PDB 3D structure from and Proteopedia for CRYGA:
1LER (3D)    
Secondary accessions: Q53ST5

Explore the universe of human proteins at neXtProt for CRYGA: NX_P11844

Explore proteomics data for CRYGA at MOPED


See CRYGA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_055432.2  
ENSEMBL proteins: 
 ENSP00000302105  

CRYGA Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for CRYGA
OriGene Protein Over-expression Lysate for CRYGA
OriGene MassSpec for CRYGA
OriGene Custom Protein Services for CRYGA
GenScript Custom Purified and Recombinant Proteins Services for CRYGA
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for CRYGA 

CRYGA Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for CRYGA
Abcam antibodies for CRYGA
Browse Antibodies at Cloud-Clone Corp.
ThermoFisher Antibodies for CRYGA
LSBio Antibodies in human, mouse, rat for CRYGA

CRYGA Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for CRYGA
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CRYGA
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.
Search eBioscience for ELISAs for CRYGA 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
2 InterPro protein domains:
 IPR001064 Beta/gamma_crystallin
 IPR011024 G_crystallin-rel

Graphical View of Domain Structure for InterPro Entry P11844

ProtoNet protein and cluster: P11844

2 Blocks protein domains:
IPB001064 Beta and gamma crystallin
IPB011024 Gamma-crystallin related


UniProtKB/Swiss-Prot: CRGA_HUMAN, P11844
Domain: Has a two-domain beta-structure, folded into four very similar Greek key motifs
Similarity: Belongs to the beta/gamma-crystallin family
Similarity: Contains 4 beta/gamma crystallin 'Greek key' domains


Find genes that share domains with CRYGA           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CRGA_HUMAN, P11844
Function: Crystallins are the dominant structural components of the vertebrate eye lens

     Genatlas biochemistry entry for CRYGA:
crystallin,gamma polypeptide A

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005212structural constituent of eye lens NAS12507494
     
Find genes that share ontologies with CRYGA           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for CRYGA:
 Decreased Salmonella enterica  

     1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Cryga):
 vision/eye 

Find genes that share phenotypes with CRYGA           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CRYGA
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CRYGA

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CRYGA
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CRYGA

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat CRYGA using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate CRYGA
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CRYGA
Predesigned siRNA for gene silencing in human, mouse, rat CRYGA

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CRYGA

Clone
Products:
     
OriGene clones in human, mouse for CRYGA (see all 6)
OriGene ORF clones in mouse, rat for CRYGA
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CRYGA (NM_014617)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRYGA
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYGA

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CRYGA
Browse ESI BIO Cell Lines and PureStem Progenitors for CRYGA 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYGA


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular3
cytosol1
mitochondrion1
nucleus1
peroxisome1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--

Find genes that share ontologies with CRYGA           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CRYGA
Interactions:

    Search GeneGlobe Interaction Network for CRYGA

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for CRYGA (ENSP000003021054) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
MYH3ENSP000002262094STRING: ENSP00000226209
NEURL2ENSP000003615964STRING: ENSP00000361596
About this table

Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001654eye development ----
GO:0002088lens development in camera-type eye IEA--
GO:0007601visual perception NAS12507494

Find genes that share ontologies with CRYGA           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CRYGA (CRGA)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for CRYGA gene: 
NM_014617.3  

Unigene Cluster for CRYGA:

Crystallin, gamma A
Hs.122566  [show with all ESTs]
Unigene Representative Sequence: BC114456
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000304502(uc002vcq.4)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CRYGA using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate CRYGA
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CRYGA
Predesigned siRNA for gene silencing in human, mouse, rat CRYGA
Clone
Products:
     
OriGene clones in human, mouse for CRYGA (see all 6)
OriGene ORF clones in mouse, rat for CRYGA
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CRYGA (NM_014617)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRYGA
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYGA
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for CRYGA
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CRYGA
  QuantiTect SYBR Green Assays in human, mouse, rat CRYGA
  QuantiFast Probe-based Assays in human, mouse, rat CRYGA

Additional mRNA sequence: 

BC114456.1 EF426311.1 

2 DOTS entries:

DT.307153  DT.120998479 

12 AceView cDNA sequences:

BM710792 BM698997 BM667614 BM698524 BM710815 BM667439 NM_014617 BX281946 
AI052518 BG207174 AA404481 AA780079 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

CRYGA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
CRYGA Expression
About this image


CRYGA expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 
 Eye (Sensory Organs)
         Lens
CRYGA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CRYGA Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.122566
    Custom PCR Arrays for CRYGA
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for CRYGA
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CRYGA
QuantiTect SYBR Green Assays in human, mouse, rat CRYGA
QuantiFast Probe-based Assays in human, mouse, rat CRYGA
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYGA

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for CRYGA gene from Selected species (see all 8)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cryga1 , 5 crystallin, gamma A1, 5 83.52(n)1
84.48(a)1
  1 (32.84 cM)5
129641  NM_007774.31  NP_031800.11 
 651003895 
zebrafish
(Danio rerio)
Actinopterygii crygmx1 crystallin, gamma MX 62.02(n)
52.33(a)
  335789  NM_001013262.1  NP_001013280.1 


ENSEMBL Gene Tree for CRYGA (if available)
TreeFam Gene Tree for CRYGA (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for CRYGA gene
CRYBB32  CRYGB2  CRYBA42  CRYBA12  CRYBB22  CRYGD2  CRYBB12  CRYGC2  
CRYBA22  CRYGN2  CRYGS2  
14 SIMAP similar genes for CRYGA using alignment to 2 protein entries:     CRGA_HUMAN (see all proteins):
CRYGB    CRYGD    CRYGC    CRYGS    DKFZp434A0627    CRYGN
CRYBA2    CRYBA1    CRYBB3    CRYBB1    CRYBA4    CRYBB2
AIM1L    AIM1

Find genes that share paralogs with CRYGA           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for CRYGA (see all 174)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1850680641,2
--208413414(+) TCTACC/TAGTAA 1 -- int10--------
rs67290511,2
C,F,A,H--208413423(+) AAGTAG/TCAGAG 1 -- int123Minor allele frequency- T:0.21NS EA NA WA 2446
rs1889834721,2
--208413498(+) CTTCTC/TCACGT 1 -- int10--------
rs24413491,2
C,A,H--208413589(+) CGGGCA/GGATCA 1 -- int10--------
rs24413501,2
C,H--208413622(+) CAGCCT/CGACCA 1 -- int17Minor allele frequency- C:0.00NA WA 14
rs134305641,2
C,F--208413696(+) taatcC/Acagtt 1 -- int11Minor allele frequency- A:0.00NA 2
rs1809104301,2
--208413727(+) AGGATG/TGATTG 1 -- int10--------
rs1863156071,2
--208413769(+) GATAGC/TGCCAT 1 -- int10--------
rs2017895741,2
C,F--208413886(+) ATTTAT/CTATGT 1 -- ut311Minor allele frequency- C:0.01EU 1323
rs1895421841,2
C--208413898(+) TCTATA/GGGGAT 1 -- ut310--------

HapMap Linkage Disequilibrium report for CRYGA (209025464 - 209028300 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for CRYGA:    About this table    
Variant IDTypeSubtypePubMed ID
dgv4418n71CNV Loss21882294
nsv834517CNV Loss17160897
nsv875747CNV Loss21882294
nsv875748CNV Gain21882294

Human Gene Mutation Database (HGMD): CRYGA
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CRYGA
DNA2.0 Custom Variant and Variant Library Synthesis for CRYGA

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 123660    OMIM disorders: --


Find genes that share disorders with CRYGA           About GenesLikeMe

1 Novoseek inferred disease relationship for CRYGA gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cataract 54.6 1 12646746 (1)

Genetic Association Database (GAD): CRYGA
Human Genome Epidemiology (HuGE) Navigator: CRYGA (1 document)

Export disorders for CRYGA gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for CRYGA gene, integrated from 10 sources (see all 22):
(articles sorted by number of sources associating them with CRYGA)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin. (PubMed id 19384013)1, 4 Kapur S....Rajkumar S. (Indian J Ophthalmol 2009)
  2. Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins. (PubMed id 12507494)1, 2 Salim A. and Zaidi Z.H. (Biochem. Biophys. Res. Commun. 2003)
  3. Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts. (PubMed id 12011157)1, 2 Santhiya S.T.... Graw J. (J. Med. Genet. 2002)
  4. Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family. (PubMed id 3670288)1, 2 Meakin S.O.... Breitman M.L. (Mol. Cell. Biol. 1987)
  5. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PubMed id 20235792)4 Uhl G.R....MunafA^ M.R. (Pharmacogenomics 2010)
  6. Lens aging: effects of crystallins. (PubMed id 19463898)1 Sharma K.K. and Santhoshkumar P. (Biochim. Biophys. Acta 2009)
  7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Structure of the crystallins. (PubMed id 10627816)1 Slingsby C. and Clout N.J. (Eye (Lond) 1999)
  10. The crystallins: genes, proteins and diseases. (PubMed id 9426193)1 Graw J. (Biol. Chem. 1997)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 1418 HGNC: 2408 AceView: CRYGA Ensembl:ENSG00000168582 euGenes: HUgn1418
ECgene: CRYGA H-InvDB: CRYGA

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for CRYGA Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for CRYGA gene:
Search GeneIP for patents involving CRYGA

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CRYGA  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for CRYGA  
 OriGene MassSpec something-or-other for CRYGA   OriGene clones in human, mouse for CRYGA  
 OriGene qSTAR qPCR primer pairs in human, mouse for CRYGA   OriGene Purified Protein for CRYGA  
 OriGene ORF clones in mouse, rat for CRYGA   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CRYGA   OriGene Custom Protein Services for CRYGA  

 
 
 Block miRNA regulation of human, mouse, rat CRYGA using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CRYGA
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRYGA Predesigned siRNA for gene silencing in human, mouse, rat CRYGA
 QuantiFast Probe-based Assays in human, mouse, rat CRYGA QuantiTect SYBR Green Assays in human, mouse, rat CRYGA
 Custom PCR Arrays for CRYGA Search Chromatin IP Primers for CRYGA
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CRYGA  Search GeneGlobe Interaction Network for CRYGA
 Regulatory tfbs in CRYGA promoter
 GenScript Custom Purified and Recombinant Proteins Services for CRYGA GenScript cDNA clones with any tag delivered in your preferred vector for CRYGA
 GenScript Custom Assay Services for CRYGA GenScript Custom overexpressing Cell Line Services for CRYGA
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for CRYGA (CRGA)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Biologicals
 Novus Tissue Slides
 Antibodies for CRYGA
 See all of Abcam's Antibodies, Kits and Proteins for CRYGA
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for CRYGA
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYGA
 Browse SwitchGear 3'UTR luciferase reporter plasmids for CRYGA
 SwitchGear Promoter luciferase reporter plasmids for CRYGA
 ThermoFisher Antibodies for CRYGA
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYGA
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CRYGA
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CRYGA
 LSBio Antibodies in human, mouse, rat for CRYGA
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for CRYGA
  Search eBioscience for proteins for CRYGA
  Search eBioscience for elisas for CRYGA
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      CRYGA gene at Home site.
Version: 3.12.224 13 Oct 2014
hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4