CRYBB3 Gene
protein-coding GIFtS: 54
GCID: GC22P025595
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crystallin, beta B3 (Previous symbol: CRYB3)
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Aliases for CRYBB3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Crystallin, Beta B31 2 | | CRYB31 2 3 5 | | Beta-B3 Crystallin2 3 | | CATCN22 5 | | Beta-Crystallin B32 | | Eye Lens Structural Protein2 |
| External Ids: | HGNC: 24001 | Entrez Gene: 14172 | Ensembl: ENSG000001000537 | OMIM: 1236305 | UniProtKB: P269983 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n334586 | |
Export aliases for CRYBB3 gene to outside databasesPrevious GC identifers: GC22P022291 GC22P023920 GC22P008543
Summaries for CRYBB3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CRYBB3: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes themajor proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lenscentral fiber cells lose their nuclei during development, these crystallins are made and then retained throughoutlife, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gammafamilies; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further dividedinto acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connectingpeptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of theC-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates ofdifferent sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins.This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in thisgene result in cataract congenital nuclear autosomal recessive type 2. (provided by RefSeq, Feb 2013) UniProtKB/Swiss-Prot: CRBB3_HUMAN, P26998Function: Crystallins are the dominant structural components of the vertebrate eye lens Gene Wiki entry for CRYBB3
|
Genomic Views for CRYBB3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CRYBB3 gene promoter: AhR HFH-3 Spz1 AML1a Brachyury Lmo2 AP-4 E47 Arnt FOXI1 Other transcription factors
Search SABiosciences Chromatin IP Primers for CRYBB3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRYBB3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23CRYBB3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P025595: view genomic region
(about GC identifiers)
Start:
|
25,595,817 bp from pter |
End:
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25,603,330 bp from pter |
Size:
|
7,514 bases |
Orientation:
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plus strand |
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Proteins for CRYBB3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CRBB3_HUMAN, P26998 (See
protein sequence)Recommended Name: Beta-crystallin B3 Size: 211 amino acids; 24252 Da
Subunit: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to bestabilized through interactions between the N-terminal arms (By similarity)
Mass spectrometry: Mass=24222; Mass_error=3; Method=Electrospray; Range=1-211; Source=PubMed:8999933;
1 PDB 3D structure from and Proteopedia for CRYBB3:3QK3 (3D)
 
Secondary accessions: Q3B7S9 Q3T1B7 Q6ISK6 Q92965 Q9UH09Explore the universe of human proteins at neXtProt for CRYBB3: NX_P26998
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P26998 CRYBB3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004067.1 ENSEMBL proteins: ENSP00000215855 ENSP00000386123 Human Recombinant Protein Products:
CRYBB3 Antibody Products: Assay Products for CRYBB3: |
Protein
Domains / Families for CRYBB3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CRYBB3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P26998ProtoNet protein and cluster: P26998 2 Blocks protein families: IPB001064 Beta and gamma crystallin IPB011024 Gamma-crystallin related
UniProtKB/Swiss-Prot: CRBB3_HUMAN, P26998Domain: Has a two-domain beta-structure, folded into four very similar Greek key motifsSimilarity: Belongs to the beta/gamma-crystallin familySimilarity: Contains 4 beta/gamma crystallin 'Greek key' domains |
Function for CRYBB3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CRBB3_HUMAN, P26998Function: Crystallins are the dominant structural components of the vertebrate eye lens Genatlas biochemistry entry for CRYBB3:crystallin,beta polypeptide B3 (see CRYB@)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CRYBB3 (NM_004076) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CRYBB3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYBB3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYBB3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005212 | structural constituent of eye lens |
IEA | -- |
CRYBB3 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CRYBB3:
|
Pathways & Interactions for CRYBB3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CRYBB3
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
 5/7 Interacting proteins for CRYBB3 (P269982, 3 ENSP000002158554) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
CRYBB3 for ontologies About GeneDecksing
|
Drugs & Compounds for CRYBB3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CRYBB3 for compounds About GeneDecksing
Browse Tocris compounds for CRYBB3 2 Novoseek chemical compound relationships for CRYBB3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| pancreozymin |
93.1 |
2 |
9183670 (1), 9645429 (1) |
| progesterone |
22.2 |
2 |
9183670 (1), 9645429 (1) |
Search CenterWatch for drugs/clinical trials and news about CRYBB3 / CRBB3 
|
Transcripts for CRYBB3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CRYBB3 gene: NM_004076.4 Unigene Cluster for CRYBB3: Crystallin, beta B3 Hs.533022 [show with all ESTs]Unigene Representative Sequence: NM_0040762 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000215855(uc003abo.1) ENST00000404334
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CRYBB3 (NM_004076) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CRYBB3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYBB3  |
Additional cDNA sequence: BC069479.1 BC102021.1 BC102022.1 BC107482.1 CR456427.1 U71216.1 1 DOTS entry: DT.40226435 22 AceView cDNA sequences: BM711382 BF726162 BC069479 BM706274 BM716587 BF726163 NM_004076 BU734551 BM697349 BU737654 BU737044 BF726571 BF726617 BF726971 BU737531 BF726385 U71216 BM699917 BF727357 BM699711 CR456427 AA652300 GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CRYBB3 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CRYBB3
|
Expression for CRYBB3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CRYBB3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GCTTCCAGGA
About this image See CRYBB3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CRYBB3
SOURCE GeneReport for Unigene cluster: Hs.533022 SABiosciences Custom PCR Arrays for CRYBB3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRYBB3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CRYBB3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRYBB3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRYBB3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYBB3 |
Orthologs for CRYBB3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CRYBB3 gene from 3/9 species (see all 9) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
CRYBB31 |
crystallin, beta B3 |
75.67(n) 75.36(a) |
  |
396108 NM_205191.1 NP_990522.1 |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.263492 |
Xenopus laevis transcribed sequence with weak similarity more |
76.44(n) |
  |
CD362449.1 |
zebrafish (Danio rerio) |
Actinopterygii |
crybb31 |
crystallin, beta B3 |
70.03(n) 68.75(a) |
  |
553184 XM_001338607.4 XP_001338643.4 |
ENSEMBL Gene Tree for CRYBB3 (if available) TreeFam Gene Tree for CRYBB3 (if available)  |
Paralogs for CRYBB3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CRYBB3 gene
- CRYBA42 CRYGB2 CRYBA12 CRYBB22 CRYGD2 CRYGA2 CRYBB12 CRYGC2
- CRYGN2 CRYBA22 CRYGS2
16 SIMAP similar genes for CRYBB3 using alignment to 2 protein entries: CRBB3_HUMAN (see all proteins):CRYBB1 CRYBB2 CRYBA2 CRYBA1 CRYBA4 CRYGN CRYGS CRYGB CRYGC CRYGA CRYGD CRYBG3 AIM1L DKFZp434A0627 DKFZp434L1713 AIM1
CRYBB3 for paralogs About GeneDecksing
|
Genomic Variants for CRYBB3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 22 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CRYBB3 (25595817 - 25603330 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for CRYBB3 5 CNVs: 2270 5357 31083 4120 34657 Human Gene Mutation Database (HGMD): CRYBB3
Locus Specific Mutation Databases (LSDB): CRYBB3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRYBB3 |
|
Disorders
/ Diseases for CRYBB3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CRYBB3 for disorders About GeneDecksing
OMIM gene information: 123630 OMIM disorders: 609741 UniProtKB/Swiss-Prot: CRBB3_HUMAN, P26998
Defects in CRYBB3 are the cause of cataract congenital nuclear autosomal recessive type 2 (CATCN2)[MIM:609741]. A congenital cataract affecting the central nucleus of the eye. Nuclear cataracts are often not highlyvisually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like,central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified corticalfibers encircling the nuclear opacity, which are referred to as cortical riders 5 diseases for CRYBB3: About MalaCardscataract, congenital nuclear, 2 cerulean cataract cataract congenital cataracts neurofibromatosis
2 Novoseek disease relationships for CRYBB3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| congenital cataract |
83.4 |
1 |
15914629 (1) |
| cataract |
65.4 |
3 |
20450675 (1), 19262743 (1) |
Export disorders for CRYBB3 gene to outside databases
|
Publications for CRYBB3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CRYBB3 gene, integrated from 9 sources (see all 22): (articles sorted by number of sources associating them with CRYBB3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens. (PubMed id 8999933)1, 2, 3 Lampi K.J....David L.L. (1997)
- Mutations in betaB3-crystallin associated with autosomal recessive cataract in two Pakistani families. (PubMed id 15914629)1, 2, 9 Riazuddin S.A.... Hejtmancik J.F. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Different evolution rates within the lens-specific beta-crystallin gene family. (PubMed id 2499686)1, 2 Aarts H.J.M....Schoenmakers J.G.G. (1989)
- A possibility of all mRNA expression in a human single lymphocyte. (PubMed id 9183670)1, 9 Kimoto Y. (1996)
- A second gene for cerulean cataracts maps to the beta crystallin region on chromosome 22. (PubMed id 8812489)1, 9 Kramer P....Litt M. (1996)
- Linkage and association analyses of intragenic SNPs in the canine beta-crystallin genes CRYBB1, CRYBB2, CRYBB3, CRYBA1 and CRYBA4 with primary cataracts in wire-haired Dachshunds. (PubMed id 18162101)1 Muller C. and Distl O. (2008)
- Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
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External Searches for CRYBB3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CRYBB3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CRYBB3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CRYBB3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for CRYBB3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CRYBB3 gene: Search GeneIP for patents involving CRYBB3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CRYBB3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for CRYBB3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CRYBB3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRYBB3 | | OriGene Protein Over-expression Lysate for CRYBB3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CRYBB3 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRYBB3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for CRYBB3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CRYBB3 | | OriGene Custom Protein Services for CRYBB3 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CRYBB3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRYBB3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRYBB3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRYBB3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRYBB3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRYBB3 |
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 |  |  |  | |
| | | Search Tocris compounds for CRYBB3 |
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 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYBB3 |
|  |  |  | | | Search ThermoFisher Antibodies for CRYBB3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRYBB3 |
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