CRYBB2P1 Gene
pseudogene GIFtS: 26
GCID: GC22P025847
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crystallin, beta B2 pseudogene 1
(Previous symbol: CRYB2B)
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Aliases
for CRYBB2P1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| Crystallin, Beta B2 Pseudogene 11 2 | | CRYB2B1 2 |
Export aliases for CRYBB2P1 gene to outside databasesPrevious GC identifers: GC22P022540 GC22P024168 GC22P025845 GC22P008791 |
Summaries
for CRYBB2P1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for CRYBB2P1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CRYBB2P1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CRYBB2P1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRYBB2P1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.2-q12.1 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.2-q12.1CRYBB2P1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P025847: view genomic region
(about GC identifiers)
Start:
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25,844,054 bp from pter |
End:
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25,916,821 bp from pter |
Size:
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72,768 bases |
Orientation:
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plus strand |
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Proteins
for CRYBB2P1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for CRYBB2P1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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Function
for CRYBB2P1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Molecular Function:
Genatlas biochemistry entry for CRYBB2P1:crystallin,beta polypeptide B2,pseudogene 1 (see CRYB@)
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for CRYBB2P1 | |  | Search LifeMap BioReagents cell lines for CRYBB2P1 |
Pathways & Interactions
for CRYBB2P1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CRYBB2P1
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Drugs & Compounds
for CRYBB2P1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for CRYBB2P1
Search CenterWatch for drugs/clinical trials and news about CRYBB2P1 
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Transcripts
for CRYBB2P1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for CRYBB2P1: Crystallin, beta B2 pseudogene 1 Hs.571835 [show with all ESTs]Unigene Representative Sequence: BC0142164 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000382734(uc003abt.3 uc003abu.3) ENST00000415709 ENST00000354451(uc003abv.3)
ENST00000509460
Additional cDNA sequence: BC004918.2 BC014216.2 BC037884.1 BC047380.1 NR_033733.1 NR_033734.1 20 DOTS entries: DT.95161733 DT.91762033 DT.100031437 DT.91762031 DT.95278732 DT.120646193 DT.100774370 DT.100774371 DT.120646122 DT.120646267 DT.70104156 DT.92052241 DT.100019422 DT.100031435 DT.91891950 DT.95286813 DT.120646216 DT.120646233 DT.121607797 DT.40271179 24/134 AceView cDNA sequences (see all 134): AI686936 BU616356 AA281467 BM510569 AW768511 BQ446689 CK902415 BU071205 BM479766 BQ900578 BE501161 AA280230 AA100391 AA235705 BE796362 AA455810 BQ433813 AW591547 AA281649 BE550183 AI355405 BE298690 BC037884 BE167853
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for CRYBB2P1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CRYBB2P1
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Expression
for CRYBB2P1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CRYBB2P1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for CRYBB2P1
SOURCE GeneReport for Unigene cluster: Hs.571835
SABiosciences Custom PCR Arrays for CRYBB2P1
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CRYBB2P1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRYBB2P1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRYBB2P1 |
Orthologs
for CRYBB2P1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for CRYBB2P1 (if available)
TreeFam Gene Tree for CRYBB2P1 (if available) |
Paralogs
for CRYBB2P1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for CRYBB2P1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for CRYBB2P1 (25844054 - 25916821 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CRYBB2P1: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for CRYBB2P1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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CRYBB2P1 for disorders About GeneDecksing
3  diseases for CRYBB2P1: About MalaCardscerulean cataract cataract neurofibromatosis
Export disorders for CRYBB2P1 gene to outside databases
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Publications
for CRYBB2P1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for CRYBB2P1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CRYBB2P1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A second gene for cerulean cataracts maps to the beta crystallin region on chromosome 22. (PubMed id 8812489)1, 9 Kramer P....Litt M. (1996)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Direct assignment of the human beta B2 and beta B3 crystallin genes to 22q11.2----q12: markers for neurofibromatosis 2. (PubMed id 2055112)1 Hulsebos T.J....Westerveld A. (1991)
- Linkage between the beta B2 and beta B3 crystallin genes in man and rat: a remnant of an ancient beta-crystallin gene cluster. (PubMed id 3436525)1 Aarts H.J....Schoenmakers J.G. (1987)
- The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5. (PubMed id 7789995)9 Hulsebos T.J....Copeland N.G. (1995)
- Regional fine mapping of the beta crystallin genes on chromosome 22 excludes these genes as physically linked markers for neurofibromatosis type 2. (PubMed id 7504514)9 Bijlsma E.K.... Hulsebos T.J.M. (1993)
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External Searches for CRYBB2P1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CRYBB2P1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing CRYBB2P1 gene
(According to HUGE)
About This Section
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Specialized Databases showing CRYBB2P1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for CRYBB2P1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CRYBB2P1 gene:
Search GeneIP for patents involving CRYBB2P1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CRYBB2P1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CRYBB2P1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRYBB2P1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRYBB2P1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRYBB2P1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRYBB2P1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRYBB2P1 |
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 | | | | |  |  |  |  | | | | Search ThermoFisher Antibodies for CRYBB2P1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CRYBB2P1 |
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