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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CRYBA1 Gene

protein-coding GIFtS: 55
GCID: GC17P027573

crystallin, beta A1

(Previous symbol: CRYB1)

Explore 8 diseases affiliated with
CRYBA1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Crystallin, Beta A1¹ ²
CRYB1¹ ² ³ ⁵
Beta-Crystallin A3²
Crystallin, Beta A3²
Eye Lens Structural Protein²

External Ids:	HGNC: 2394¹	Entrez Gene: 1411²	Ensembl: ENSG00000108255⁷	OMIM: 123610⁵	UniProtKB: P05813³

Export aliases for CRYBA1 gene to outside databases

Previous GC identifers: GC17M027303 GC17P029473 GC17P027425 GC17P027719 GC17P024598 GC17P023782

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CRYBA1:

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the

major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens

central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout

life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma

families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided

into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting

peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the

C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of

different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins.

This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a

single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate

translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with

sutural opacities'. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CRBA1_HUMAN, P05813

Function: Crystallins are the dominant structural components of the vertebrate eye lens

Gene Wiki entry for CRYBA1 (Crystallin, beta A1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010799.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CRYBA1 gene promoter:
Tal-1 AP-1 Pax-2 Lmo2 Pax-2a Tal-1beta E47 POU2F1 POU2F1a ITF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CRYBA1 promoter sequence

Search SABiosciences Chromatin IP Primers for CRYBA1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRYBA1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q11.2 HGNC cytogenetic band: 17q11.2-q12

CRYBA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRYBA1 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P027573: view genomic region (about GC identifiers)

Start:	27,573,875 bp from pter	End:	27,581,512 bp from pter
Size:	7,638 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CRBA1_HUMAN, P05813 (See protein sequence)

Recommended Name: Beta-crystallin A3

Size: 215 amino acids; 25150 Da

Subunit: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be

stabilized through interactions between the N-terminal arms (By similarity)

Mass spectrometry: Mass=25192; Mass_error=3; Method=Electrospray; Range=1-215; Source=PubMed:8999933;

Mass spectrometry: Mass=25192; Method=Electrospray; Range=1-215; Source=PubMed:15576560;

Mass spectrometry: Mass=23101; Mass_error=3; Method=Electrospray; Range=19-215; Source=PubMed:8999933;

Mass spectrometry: Mass=23102; Method=Electrospray; Range=19-215; Source=PubMed:15576560;

Mass spectrometry: Mass=22646; Method=Electrospray; Range=23-215; Source=PubMed:15576560;

Mass spectrometry: Mass=22351; Method=Electrospray; Range=26-215; Source=PubMed:15576560;

Mass spectrometry: Mass=22294; Method=Electrospray; Range=27-215; Source=PubMed:15576560;

Secondary accessions: Q13633 Q14CM9

Alternative initiation: 2 isoforms: P05813-1 P05813-2 (Initiator Met-1 is removed. Contains a N-acetylalanine at position 2)

Explore the universe of human proteins at neXtProt for CRYBA1: NX_P05813

Post-translational modifications:

Specific cleavages in the N-terminal arm occur during lens maturation and give rise to several truncated forms.

Cleavages do not seem to have adverse effects on solubility¹

S-methylation and glutathionylation occur in normal young lenses and do not seem to be detrimental¹

Isoform A1 initiator methionine is removed. The new N-terminal amino acid is then N-acetylated¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P05813

CRYBA1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_005199.2

ENSEMBL proteins:

ENSP00000225387 ENSP00000464368

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Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005625	soluble fraction	--	--
GO:0005634	nucleus	ISS	--
GO:0005737	cytoplasm	ISS	--

CRYBA1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CRYBA1 for domains About GeneDecksing

2 InterPro domains/families:

IPR001064 Beta/gamma_crystallin

IPR011024 G_crystallin-rel

Graphical View of Domain Structure for InterPro Entry P05813

ProtoNet protein and cluster: P05813

2 Blocks protein families:

IPB001064 Beta and gamma crystallin

IPB011024 Gamma-crystallin related

UniProtKB/Swiss-Prot: CRBA1_HUMAN, P05813

Domain: Has a two-domain beta-structure, folded into four very similar Greek key motifs

Similarity: Belongs to the beta/gamma-crystallin family

Similarity: Contains 4 beta/gamma crystallin 'Greek key' domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CRBA1_HUMAN, P05813

Function: Crystallins are the dominant structural components of the vertebrate eye lens

Genatlas biochemistry entry for CRYBA1:

crystallin,beta polypeptide A1

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRYBA1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--
GO:0005212	structural constituent of eye lens	IEA	--
GO:0042803	protein homodimerization activity	IEA	--

CRYBA1 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Cryba1):

vision/eye

CRYBA1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CRYBA1

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5 Interacting proteins for CRYBA1 (P05813^{2, 3} ENSP00000225387⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CRYAB	P02511²^,³, ENSP00000227251⁴	MINT-3388193 MINT-3388174 I2D: score=1 STRING: ENSP00000227251
CRYBB3	P26998³, ENSP00000215855⁴	I2D: score=1 STRING: ENSP00000215855
CRYBB1	P53674³, ENSP00000215939⁴	I2D: score=2 STRING: ENSP00000215939
CRYBB2	P43320³	I2D: score=1
--	ENSP00000215861⁴	STRING: ENSP00000215861

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002088	lens development in camera-type eye	IEA	--
GO:0007601	visual perception	NAS	8999933
GO:0043010	camera-type eye development	--	--

CRYBA1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CRYBA1
Search CenterWatch for drugs/clinical trials and news about CRYBA1 / CRBA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CRYBA1 gene:

NM_005208.4

Unigene Cluster for CRYBA1:

Crystallin, beta A1

Hs.46275 [show with all ESTs]

Unigene Representative Sequence: NM_005208

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000225387(uc002hdw.3) ENST00000484605

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Additional cDNA sequence:

BC069537.1 BC113693.1 U59058.1

3 DOTS entries:

DT.97854927 DT.97854926 DT.100744937

24/146 AceView cDNA sequences (see all 146):

BM696850 BM667661 BM698199 BU735217 BF726948 BM667557 BU735164 BM706265

BM696648 BF727263 BM704988 BM722553 BM697298 BU735172 BM698135 BM696429

AA446764 BU735727 BF726855 BM697711 AI078257 BU735101 BM697944 BU737001

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for CRYBA1 About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b
SP1:
SP2:							-

ECgene alternative splicing isoforms for CRYBA1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CRYBA1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGACCTTGCT

About this image

CRYBA1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Lens

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CRYBA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CRYBA1

SOURCE GeneReport for Unigene cluster: Hs.46275

SABiosciences Custom PCR Arrays for CRYBA1

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CRYBA1 gene from 4/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CRYBA1¹	crystallin, beta A1	78.91(n) 84.19(a)		396499 NM_205502.2 NP_990833.2
lizard (Anolis carolinensis)	Reptilia	CRYBA1⁶	--	77(a)	1 ↔ 1	GL343462.1(268859-278032)
African clawed frog (Xenopus laevis)	Amphibia	Xl.28806²	Xenopus laevis transcribed sequence with moderate similarity more	79.4(n)		CD329982.1
zebrafish (Danio rerio)	Actinopterygii	cryba1a¹	crystallin, beta A1a	76.87(n) 81.63(a)		436683 NM_001002410.1 NP_001002410.1

ENSEMBL Gene Tree for CRYBA1 (if available)
TreeFam Gene Tree for CRYBA1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CRYBA1 gene

CRYBB3² CRYBA4² CRYGB² CRYBB2² CRYGD² CRYGA² CRYBB1² CRYGC²

CRYBA2² CRYGN² CRYGS²

15 SIMAP similar genes for CRYBA1 using alignment to 2 protein entries: CRBA1_HUMAN (see all proteins):

CRYBA4 CRYBA2 CRYBB1 CRYBB2 CRYBB3 CRYGN

CRYGA CRYGB CRYGD CRYGC CRYBG3 CRYGS

AIM1 AIM1L DKFZp434L1713

CRYBA1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs1047790^1,2	C,F,O,A,H,	untested	27580756(-)	`AACCAG/ACCCAT`	2	/G	syn¹		39		NA EA MN NS WA CSA EU	9389
rs72819445^1,2	C,F,	--	23781186(+)	`AGCAAG/AGACAT`	1	--	us2k¹		2		WA NA	238
rs78498560^1,2		--	23781343(+)	`AACGAC/TGACCC`	1	--	us2k¹		0	--	--	--	--
rs17654416^1,2	C,F,H,	--	23781513(+)	`AACAGA/GTAAGT`	1	--	us2k¹ tfbs³		21		NA NS EA	2262
rs35814755^1,2	C,F,	--	23782044(+)	`TATAAA/GTACAG`	1	--	us2k¹		4		NA EA	244
rs72819446^1,2	C,	--	23782275(+)	`TACTCA/GTGGCA`	1	--	us2k¹		3		CSA WA NA	240
rs35401958^1,2	C	--	23783001(+)	`ACTTTT/CCCTTC`	1	--	int¹		1		NA	2
rs78097051^1,2		--	23783185(+)	`GGGCCG/AGACAT`	1	--	int¹		1		WA	118
rs60299773^1,2	C,F,	--	23783439(+)	`AGAAGG/TCAGGA`	1	--	int¹		2		WA NA	238
rs16964939^1,2	C,F,H,	--	23784372(+)	`ATGTCG/AAAGCT`	1	--	int¹		11		NA NS EA WA	1068

HapMap Linkage Disequilibrium report for CRYBA1 (27573875 - 27581512 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CRYBA1: --
Human Gene Mutation Database (HGMD): CRYBA1

Locus Specific Mutation Databases (LSDB): CRYBA1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRYBA1

DNA2.0 Custom Variant and Variant Library Synthesis for CRYBA1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CRYBA1 for disorders           About GeneDecksing

OMIM gene information: 123610
OMIM disorders: 600881
UniProtKB/Swiss-Prot: CRBA1_HUMAN, P05813

Defects in CRYBA1 are the cause of cataract congenital zonular with sutural opacities (CCZS) [MIM:600881]. A

form of zonular cataract. Zonular or lamellar cataracts are concentric opacities, broad or narrow, usually consisting

of powdery white dots affecting one lamella or zonule of an otherwise clear lens

8 diseases for CRYBA1: About MalaCards

cataract, congenital zonular, with sutural opacities autosomal dominant disease cataract posterior polar cataract

cataract, zonular congenital cataracts neurofibromatosis blindness

1 disease from the University of Copenhagen DISEASES database for CRYBA1:

Posterior polar cataract

2 Novoseek disease relationships for CRYBA1 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
congenital cataract	84.7	1	17653060 (1)
cataract	70.2	4	10585769 (1), 9788845 (1), 19262743 (1)

Genetic Association Database (GAD): CRYBA1

Export disorders for CRYBA1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CRYBA1 gene, integrated from 9 sources (see all 49):
(articles sorted by number of sources associating them with CRYBA1)

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Characterization of the human beta-crystallin gene Hu beta A3/A1 reveals ancestral relationships among the beta gamma-crystallin superfamily. (PubMed id 3745196)^{1, 2, 3} Hogg D.... Breitman M.L. (1986)
Autosomal dominant zonular cataract with sutural opacities is associated with a splice mutation in the betaA3/A1-crystallin gene. (PubMed id 9788845)^{1, 2, 9} Kannabiran C.... Hejtmancik J.F. (1998)
Modifications of human betaA1/betaA3-crystallins include S- methylation, glutathiolation, and truncation. (PubMed id 15576560)^{1, 2} Lapko V.N.... Smith J.B. (2005)
A deletion mutation in the betaA1/A3 crystallin gene ( CRYBA1/A3) is associated with autosomal dominant congenital nuclear cataract in a Chinese family. (PubMed id 14598164)^{1, 4} Qi Y....Li Y. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens. (PubMed id 8999933)^{1, 2} Lampi K.J....David L.L. (1997)
Assignment of a human beta-crystallin gene to 17cen-q23. (PubMed id 3770741)^{1, 3} Sparkes R.S....Horwitz J. (1986)
Two Chinese families with pulverulent congenital cata racts and deltaG91 CRYBA1 mutations. (PubMed id 17653060)^{1, 9} Lu S....Larsson C. (2007)
Mutation in the betaA3/A1-crystallin encoding gene Cryba1 causes a dominant cataract in the mouse. (PubMed id 10585769)^{1, 9} Graw J....Hrabe de Angelis M. (1999)
Crystallin gene mutations in Indian families with inherited pediatric cataract. (PubMed id 18587492)^{1, 9} Devi R.R....Hejtmancik J.F. (2008)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1411	HGNC: 2394	AceView: CRYBA1	Ensembl:ENSG00000108255	euGenes: HUgn1411
ECgene: CRYBA1	H-InvDB: CRYBA1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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PharmGKB entry for CRYBA1	Pharmacogenomics, SNPs, Pathways

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