CRTC3 Gene
protein-coding GIFtS: 56
GCID: GC15P091073
|
|
CREB regulated transcription coactivator 3
| |
Aliases
for CRTC3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CREB Regulated Transcription Coactivator 31 2 | | CREB-Regulated Transcription Coactivator 32 | | TORC32 3 5 | | Transducer Of Regulated CAMP Response Element-Binding Protein (CREB) 32 | | Transducer Of Regulated CAMP Response Element-Binding Protein 32 3 | | Transducer Of Regulated CREB Protein 32 | | TORC-32 3 | | Transducer Of CREB Protein 33 | | FLJ218681 | | |
Export aliases for CRTC3 gene to outside databasesPrevious GC identifers: GC15P088875 GC15P067184 |
Summaries
for CRTC3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CRTC3:
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependentgene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The proteinencoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. Atranslocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein,has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants thatencode different protein isoforms. (provided by RefSeq, Jul 2012)
UniProtKB/Swiss-Prot: CRTC3_HUMAN, Q6UUV7Function: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)
Gene Wiki entry for CRTC3
|
Genomic Views
for CRTC3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CRTC3 gene promoter:
AML1a ATF-2 CREB CRE-BP1 Nkx6-1 CP2 deltaCREB Msx-1 Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for CRTC3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRTC3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.1 Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26.1CRTC3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P091073: view genomic region
(about GC identifiers)
Start:
|
91,073,157 bp from pter |
End:
|
91,188,577 bp from pter |
Size:
|
115,421 bases |
Orientation:
|
plus strand |
|
Proteins
for CRTC3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CRTC3_HUMAN, Q6UUV7 (See
protein sequence)Recommended Name: CREB-regulated transcription coactivator 3 Size: 619 amino acids; 66959 Da
Subunit: Binding, as a tetramer, through its N-terminal region, with the bZIP domain of CREB1 enhances recruitment ofTAF4 to the promoter. 'Arg-314' in the bZIP domain of CREB1 is essential for this interaction (By similarity).Interaction with HTLV-1 TAX enhances its transcriptional activity. Interacts, via the N-terminal with the ankyrinrepeats of BCL3, to form a complex with CREB1 on CRE and TxRE responsive elements and represses HTLV-1 LTR-mediatedtranscription
Subcellular location: Nucleus. Cytoplasm. Note=Appears to be mainly nuclear
Sequence caution: Sequence=BAC03424.1; Type=Frameshift; Positions=82;
Secondary accessions: Q6DK61 Q6DK62 Q8NF38 Q9H6U2Alternative splicing: 2 isoforms: Q6UUV7-1 Q6UUV7-3 Explore the universe of human proteins at neXtProt for CRTC3: NX_Q6UUV7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6UUV7
CRTC3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001036039.1 NP_073606.3
ENSEMBL proteins: ENSP00000416573 ENSP00000452640 ENSP00000268184 ENSP00000452676
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CRTC3 for ontologies About GeneDecksing
CRTC3 Antibody Products:
Assay Products for CRTC3: |
Protein
Domains /
Families
for CRTC3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CRTC3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6UUV7ProtoNet protein and cluster: Q6UUV7 UniProtKB/Swiss-Prot: CRTC3_HUMAN, Q6UUV7Similarity: Belongs to the TORC family |
Function
for CRTC3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CRTC3_HUMAN, Q6UUV7Function: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CRTC3 (NM_022769) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CRTC3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRTC3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRTC3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008140 | cAMP response element binding protein binding |
IEA | -- |
CRTC3 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for CRTC3:
Animal Models:
Mouse knock-out Crtc3tm1Mmy for CRTC3
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Crtc3):
CRTC3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CRTC3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glucose / Energy Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for CRTC3
CRTC3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CRTC3
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/7 Interacting proteins for CRTC3 (Q6UUV73 ENSP000002681844) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0019048 | virus-host interaction |
IEA | -- | | GO:0032793 | positive regulation of CREB transcription factor activity |
IEA | -- | | GO:0044419 | interspecies interaction between organisms |
-- | -- | | GO:0051289 | protein homotetramerization |
IEA | -- |
CRTC3 for ontologies About GeneDecksing
|
Drugs & Compounds
for CRTC3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CRTC3
1 HMDB Compound for CRTC3 About this table
Search CenterWatch for drugs/clinical trials and news about CRTC3
|
Transcripts
for CRTC3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CRTC3 gene (2 alternative transcripts): NM_001042574.2 NM_022769.4 Unigene Cluster for CRTC3: CREB regulated transcription coactivator 3 Hs.567572 [show with all ESTs]Unigene Representative Sequence: NM_02276914 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000420329(uc002bpp.3 uc002bpo.3) ENST00000560098(uc002bpn.3)
ENST00000561218 ENST00000268184 ENST00000558619 ENST00000560927 ENST00000561119
ENST00000558005 ENST00000561290 ENST00000558496 ENST00000561255 ENST00000560047
ENST00000560320 ENST00000558167
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CRTC3 (NM_022769) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CRTC3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRTC3 |
Additional cDNA sequence: AK024981.1 AK025521.1 AK074170.1 AK090443.1 AK225300.1 AL360259.1 AY360173.1 BC019060.2 BC074730.2 BC074731.2 11 DOTS entries: DT.453027 DT.40234550 DT.95134569 DT.121018996 DT.439611 DT.121019056 DT.121019062 DT.91737590 DT.95213901 DT.91716241 DT.91925295 24/125 AceView cDNA sequences (see all 125): BM848265 BF593236 BU528448 BM667305 AL360259 CD678851 BQ945777 BM698139 CA427035 BC019060 BF434743 AI015510 BC074730 AA724679 BU168168 BX472107 AK074170 AA897770 BM784357 BQ068919 BI260655 BX280445 NM_022769 CA391684
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CRTC3 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 19b |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for CRTC3
|
Expression
for CRTC3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CRTC3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGGGACCA
About this image
See CRTC3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CRTC3
SOURCE GeneReport for Unigene cluster: Hs.567572
UniProtKB/Swiss-Prot: CRTC3_HUMAN, Q6UUV7Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain,colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen andstomach
SABiosciences Custom PCR Arrays for CRTC3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRTC3
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRTC3 |
Orthologs
for CRTC3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CRTC3 gene from 2/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
CR382298.26 |
-- |
49(a) |
1 ↔ 1 |
7(52005062-52088616) |
fruit fly
(Drosophila melanogaster) |
Insecta |
TORC6 |
TORC |
13(a) |
1 → many |
3L(17653208-17662334) |
ENSEMBL Gene Tree for CRTC3 (if available)
TreeFam Gene Tree for CRTC3 (if available) |
Paralogs
for CRTC3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CRTC3 gene
- CRTC12 CRTC22
3 SIMAP similar genes for CRTC3 using alignment to 3 protein entries: CRTC3_HUMAN (see all proteins):CRTC3/MAML2 fusion FLJ00243 CRTC2
CRTC3 for paralogs About GeneDecksing
|
Genomic Variants
for CRTC3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CRTC3 (91073157 - 91188577 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for CRTC3
1 CNV: 102158
9 Indels: 45379 40117 40118 60189 61472 42021 25577 11809 11103 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRTC3 |
|
Disorders
/ Diseases
for CRTC3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CRTC3 for disorders About GeneDecksing
OMIM gene information: 608986
OMIM disorders: --
6  diseases for CRTC3: About MalaCardsmucoepidermoid carcinoma human t-cell leukemia virus type 1 carcinoma t-cell leukemia
leukemia prostatitis
1 disease from the University of Copenhagen DISEASES database for CRTC3:Mucoepidermoid carcinoma Human Genome Epidemiology (HuGE) Navigator: CRTC3 (2 documents)
Export disorders for CRTC3 gene to outside databases
|
Publications
for CRTC3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CRTC3 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with CRTC3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. (PubMed id 14506290)1, 2, 3 Iourgenko V.... Labow M.A. (2003)
- TORCs: transducers of regulated CREB activity. (PubMed id 14536081)1, 2, 3 Conkright M.D.... Montminy M. (2003)
- Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3. (PubMed id 15466468)1, 2, 9 Koga H.... Shimotohno K. (2004)
- BCL3 acts as a negative regulator of transcription from the human T- cell leukemia virus type 1 long terminal repeat through interactions with TORC3. (PubMed id 17644518)1, 2 Hishiki T.... Shimotohno K. (2007)
- Transducer of regulated CREB-binding proteins (TORCs) induce PGC- 1alpha transcription and mitochondrial biogenesis in muscle cells. (PubMed id 16980408)1, 2 Wu Z.... Stevenson S.C. (2006)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Role of cAMP-responsive element-binding protein (CREB )-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondr ial biogenesis and stress response in liver cells. (PubMed id 21536665)1 Than T.A....Kaplowitz N. (2011)
- Impact of CRTC1/3-MAML2 fusions on histological class ification and prognosis of mucoepidermoid carcinoma. (PubMed id 21668476)1 Okumura Y....Inagaki H. (2011)
- Whole genome association scan for genetic polymorphis ms influencing information processing speed. (PubMed id 21130836)1 Luciano M....Deary I.J. (2011)
- CRTC3 links catecholamine signalling to energy balanc e. (PubMed id 21164481)1 Song Y....Montminy M. (2010)
|
External Searches for CRTC3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CRTC3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CRTC3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CRTC3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CRTC3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CRTC3 gene:
Search GeneIP for patents involving CRTC3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CRTC3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for CRTC3 | | OriGene shRNA RFP for CRTC3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CRTC3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRTC3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CRTC3 | | OriGene 3'-UTR Clone for CRTC3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRTC3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CRTC3 | | OriGene Custom Protein Services for CRTC3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CRTC3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRTC3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRTC3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRTC3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRTC3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRTC3 |
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| | Antibodies & Assays for CRTC3 (TORC3) |
| | | | Search Tocris compounds for CRTC3 |
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 | | | CRTC3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRTC3 |
|  |  |  | | | | ThermoFisher Antibody for CRTC3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRTC3 |
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