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CRTAC1 Gene

protein-coding   GIFtS: 53
GCID: GC10M099614

Cartilage Acidic Protein 1

Alzheimer's & Parkinson's Diseases Congress
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at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cartilage Acidic Protein 11 2     Acidic Secreted Protein In Cartilage2
ASPIC2 3     Chondrocyte Expressed Protein 68 KDa CEP-682
ASPIC12 3     68 KDa Chondrocyte-Expressed Protein3
CEP-682 3     CEP683

External Ids:    HGNC: 148821   Entrez Gene: 551182   Ensembl: ENSG000000957137   OMIM: 6062765   UniProtKB: Q9NQ793   

Export aliases for CRTAC1 gene to outside databases

Previous GC identifers: GC10M098518 GC10M098858 GC10M099755 GC10M099289 GC10M093250


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CRTAC1 Gene:
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of
articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and
mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that
this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have
been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple
transcript variants. (provided by RefSeq, Aug 2011)

GeneCards Summary for CRTAC1 Gene:
CRTAC1 (cartilage acidic protein 1) is a protein-coding gene. Diseases associated with CRTAC1 include glomus tumor, and neurofibromatosis. GO annotations related to this gene include calcium ion binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CRTAC1 gene promoter:
         E2F-4   E2F-3a   E2F-5   Pax-5   NRSF form 1   CUTL1   E2F-2   NRSF form 2   E2F   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCRTAC1 promoter sequence
   Search Chromatin IP Primers for CRTAC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRTAC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22   Ensembl cytogenetic band:  10q24.2   HGNC cytogenetic band: 10q22

CRTAC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRTAC1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M099614:  view genomic region     (about GC identifiers)

Start:
99,624,757 bp from pter      End:
99,790,585 bp from pter
Size:
165,829 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CRAC1_HUMAN, Q9NQ79 (See protein sequence)
Recommended Name: Cartilage acidic protein 1 precursor  
Size: 661 amino acids; 71421 Da
Sequence caution: Sequence=AAH34245.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA91540.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAB98268.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAB98269.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=CAI12584.1; Type=Erroneous gene model prediction;
Secondary accessions: B1ALN4 Q5T4F8 Q8N4H6 Q8TE52 Q9NQ78 Q9NQ80 Q9NW46
Alternative splicing: 3 isoforms:  Q9NQ79-1   Q9NQ79-2   Q9NQ79-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CRTAC1: NX_Q9NQ79

Explore proteomics data for CRTAC1 at MOPED

Post-translational modifications: 

  • O-glycosylated1
  • Glycosylation2 at Thr608, Thr618, Thr619, Thr621, Thr626
  • Modification sites at PhosphoSitePlus

  • See CRTAC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001193457.1  NP_060528.3  

    ENSEMBL proteins: 
     ENSP00000408445   ENSP00000359629   ENSP00000404549   ENSP00000310810   ENSP00000298819  
     ENSP00000359623  

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    Cloud-Clone Corp. CLIAs for CRTAC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011519 UnbV_ASPIC
     IPR027039 Crtac1
     IPR018097 EGF_Ca-bd_CS
     IPR001881 EGF-like_Ca-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q9NQ79

    ProtoNet protein and cluster: Q9NQ79

    1 Blocks protein domain: IPB001881 EGF-like calcium-binding

    UniProtKB/Swiss-Prot: CRAC1_HUMAN, Q9NQ79
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 4 FG-GAP repeats


    CRTAC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CRAC1_HUMAN, Q9NQ79
    Induction: Up-regulated by BMP4 (at protein level). Up-regulated in mesenchymal stem cells undergoing chondrogenic
    differentiation and by BMP4

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    CRTAC1 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Crtac1):
     cellular  nervous system 

    CRTAC1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Crtac1tm1Kota for CRTAC1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CRTAC1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CRTAC1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CRTAC1

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    miRTarBase miRNAs that target CRTAC1:
    hsa-mir-29c-3p (MIRT020387)

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRTAC1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CRAC1_HUMAN, Q9NQ79: Secreted, extracellular space, extracellular matrix
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane2
    lysosome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--

    CRTAC1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CRTAC1
    Interactions:

        Search GeneGlobe Interaction Network for CRTAC1

    1 Interacting protein for CRTAC1 (Q9NQ793) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHABP319463I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CRTAC1 (CRAC1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CRTAC1 gene (2 alternative transcripts): 
    NM_001206528.2  NM_018058.6  

    Unigene Cluster for CRTAC1:

    Cartilage acidic protein 1
    Hs.500736  [show with all ESTs]
    Unigene Representative Sequence: NM_018058
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000413387 ENST00000370597(uc001kot.2 uc001kou.2) ENST00000436034
    ENST00000309155 ENST00000468549 ENST00000298819 ENST00000370591(uc001kov.3)


    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat CRTAC1

    Additional mRNA sequence: 

    AJ276171.1 AJ279016.1 AJ421515.1 AK001182.1 AK057190.1 AK292084.1 BC034245.1 

    8 DOTS entries:

    DT.100814327  DT.97839043  DT.430096  DT.121287669  DT.121287671  DT.97770427  DT.97792350  DT.121287663 

    Selected AceView cDNA sequences (see all 102):

    BQ067249 AJ421515 AJ276171 AA365484 BC034245 NM_018058 BQ182286 BM699706 
    AK001182 CA434127 BM673713 BQ183029 AA938499 BG820409 BU687942 CA388867 
    BF727076 AA485275 BF725127 BU727696 BM707643 BF727075 AJ279016 F03192 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CRTAC1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^ 21
    SP1:        -     -     -           -     -                                                                             -                             -         
    SP2:                                -     -                                                                             -                                       
    SP3:                                                                                                                    -           -                 -         
    SP4:                                                                                                                                                            
    SP5:              -     -           -     -                                                                                                                     


    ECgene alternative splicing isoforms for CRTAC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CRTAC1 expression in normal human tissues (normalized intensities)      CRTAC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACATTACTT
    CRTAC1 Expression
    About this image


    CRTAC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Bone (Muscoskeletal System)
             Articular chondrocyte-like cells
     
     Cartilage (Muscoskeletal System)
             Articular chondrocyte-like cells
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Gonad
             Primordial Germ Cells Allantois
     
     Neural Tube (Nervous System)
             Telencephalon
    CRTAC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CRTAC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.500736

    UniProtKB/Swiss-Prot: CRAC1_HUMAN, Q9NQ79
    Tissue specificity: Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level).
    Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in
    cartilage, bone, cultured chondrocytes and lung, and at low levels in heart. Not detected in osteoblasts

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CRTAC1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Crtac11 , 5 cartilage acidic protein 11, 5 88.68(n)1
    93.95(a)1
      19 (36.07 cM)5
    728321  NM_145123.41  NP_660105.31 
     422830375 
    chicken
    (Gallus gallus)
    Aves CRTAC11 cartilage acidic protein 1 76.05(n)
    80.91(a)
      425346  NM_001080211.1  NP_001073680.1 
    lizard
    (Anolis carolinensis)
    Reptilia CRTAC16
    cartilage acidic protein 1
    77(a)
    1 ↔ 1
    3(38965655-39004618)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia crtac11 cartilage acidic protein 1 70.01(n)
    79(a)
      779826  NM_001078905.1  NP_001072373.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.62102 Transcribed sequence with weak similarity to protein more 71.58(n)    57077573 


    ENSEMBL Gene Tree for CRTAC1 (if available)
    TreeFam Gene Tree for CRTAC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CRTAC1 (see all 3465)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs38387411,2
    C,F--93263479(+) GGGGCT/-TTTTT 1 -- int1 trp33Minor allele frequency- -:0.50NA 6
    rs560014481,2
    C--93275146(+) CACAC-/AC    
       
    /ACAC
    TCTCA
    2 -- int11NA 2
    rs1470117801,2
    C--93289078(+) ACCAG-/AAAAAA 2 -- int10--------
    rs719500651,2
    C--93292526(+) TGTGTGTAG/-  
            
    GGTGG
    2 -- int11Minor allele frequency- -:0.50CSA 2
    rs665315591,2
    C--93292527(+) GTGTG-/TAGG  
            
    GTGGT
    2 -- int10--------
    rs2004776401,2
    --93297542(+) TCTCT-/CAGACTG 2 -- int10--------
    rs680712611,2
    C--93297543(+) CTCTC-/AG/GA 
            
    ACTGC
    2 -- int10--------
    rs558345901,2
    C--93297544(+) TCTCA-/GACTGCA 2 -- int10--------
    rs2007030431,2
    --93304001(+) ATCCA-/CCA   
       CCCCC
    CCCCG
    2 -- int10--------
    rs107143471,2
    C--93304004(+) CACCAC/-CCCCC 2 -- int11Minor allele frequency- -:0.50CSA 2

    HapMap Linkage Disequilibrium report for CRTAC1 (99624757 - 99790585 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for CRTAC1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660852CNV Deletion23128226
    nsv509364CNV Insertion20534489
    esv270898CNV Insertion20981092
    nsv513013CNV Insertion21212237
    nsv7510CNV Insertion18451855
    nsv25263CNV Loss16902084
    nsv831953CNV Gain17160897
    nsv819567CNV Gain19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CRTAC1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606276    OMIM disorders: --

    8 diseases for CRTAC1:    About MalaCards
    glomus tumor    neurofibromatosis    bone fracture    botulism
    primary hyperparathyroidism    hyperparathyroidism    alzheimer's disease    cerebritis

    1 disease from the University of Copenhagen DISEASES database for CRTAC1:
    Botulism

    CRTAC1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): CRTAC1
    Human Genome Epidemiology (HuGE) Navigator: CRTAC1 (2 documents)

    Export disorders for CRTAC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CRTAC1 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with CRTAC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chondrocyte expressed protein-68 (CEP-68), a novel human marker gene for cultured chondrocytes. (PubMed id 11139377)1, 2, 3 Steck E.... Richter W. (Biochem. J. 2001)
    2. Chondrocyte secreted CRTAC1: a glycosylated extracellular matrix molecule of human articular cartilage. (PubMed id 17074475)1, 2, 9 Steck E.... Richter W. (Matrix Biol. 2007)
    3. A genome-wide association study of the metabolic syndrome in Indian Asian men. (PubMed id 20694148)1, 4 Zabaneh D. and Balding D.J. (PLoS ONE 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. CRTAC1 homolog proteins are conserved from cyanobacteria to man and secreted by the teleost fish pituitary gland. (PubMed id 20171266)1, 9 Redruello B....Power D.M. (Gene 2010)
    9. Genes up- or down-regulated by high calcium medium in parathyroid tissue explants from patients with primary hyperparathyroidism. (PubMed id 19952464)1, 9 Nakajima K....Sato K. (Endocr. J. 2010)
    10. Detection of bone and cartilage-related proteins in plasma of patients with a bone fracture using liquid chromatography-mass spectrometry. (PubMed id 17602227)1, 9 Grgurevic L....Vukicevic S. (Int Orthop 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55118 HGNC: 14882 AceView: CRTAC1 Ensembl:ENSG00000095713 euGenes: HUgn55118
    ECgene: CRTAC1 H-InvDB: CRTAC1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CRTAC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CRTAC1 gene:
    Search GeneIP for patents involving CRTAC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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