CRMP1 Gene(Protein Coding)

Collapsin Response Mediator Protein 1

GCID:: GC04M005815

GIFtS:: 58

Genes Participants

Aliases for CRMP1 Gene

Collapsin Response Mediator Protein 1 ² ³ ⁴ ⁵
Unc-33-Like Phosphoprotein 3 ³ ⁴
CRMP-1 ³ ⁴
DPYSL1 ³ ⁴
ULIP-3 ³ ⁴
DRP-1 ³ ⁴
Dihydropyrimidinase-Like 1 ³
ULIP3 ⁴
DRP1 ³

External Ids for CRMP1 Gene

HGNC: 2365
Entrez Gene: 1400
Ensembl: ENSG00000072832
OMIM: 602462
UniProtKB: Q14194

Previous GeneCards Identifiers for CRMP1 Gene

GC04M005704
GC04P005871
GC04M005887
GC04M005940

Export aliases for CRMP1 gene to outside databases

Summaries for CRMP1 Gene

Entrez Gene Summary for CRMP1 Gene

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

GeneCards Summary for CRMP1 Gene

CRMP1 (Collapsin Response Mediator Protein 1) is a Protein Coding gene. Among its related pathways are Guidance Cues and Growth Cone Motility and Semaphorin Signaling. GO annotations related to this gene include hydrolase activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. An important paralog of this gene is DPYSL5.

UniProtKB/Swiss-Prot for CRMP1 Gene

DPYL1_HUMAN,Q14194

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.

Gene Wiki entry for CRMP1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CRMP1 Gene

Genomics for CRMP1 Gene

Regulatory Elements for CRMP1 Gene

Enhancers for CRMP1 Gene

GeneHancer Identifier	Score	Enhancer Sources	TSS distance (kb)	Number of Genes Away	Size (kb)	Transcription Factor Binding Sites within enhancer	Other Gene Targets for Enhancer

Enhancers around CRMP1 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the CRMP1 gene promoter:

See All at QIAGEN

Regulatory Element Products

Genomic Location for CRMP1 Gene

Chromosome:: 4

Start:: 5,748,084 bp from pter
End:: 5,893,083 bp from pter

Size:: 145,000 bases
Orientation:: Minus strand

Genomic View for CRMP1 Gene

Genes around CRMP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:

4p16.2 by Ensembl
4p16.1 by Entrez Gene
4p16.1 by HGNC

CRMP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

Genomic Location for CRMP1 Gene — Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CRMP1 Gene

Proteins for CRMP1 Gene

Protein details for CRMP1 Gene (UniProtKB/Swiss-Prot)
Protein Symbol:

Q14194-DPYL1_HUMAN

Recommended name:

Dihydropyrimidinase-related protein 1

Protein Accession:

Q14194

Secondary Accessions:
- A0EJG6
- Q13024
- Q4W5F1
- Q96TC8
Protein attributes for CRMP1 Gene
Size:

572 amino acids

Molecular mass:

62184 Da
Quaternary structure:
Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5. Interacts with PLXNA1 (By similarity).
Three dimensional structures from OCA and Proteopedia for CRMP1 Gene
- 4B3Z (3D)
Alternative splice isoforms for CRMP1 Gene
UniProtKB/Swiss-Prot:
Q14194-1

Q14194-2

neXtProt entry for CRMP1 Gene

Proteomics data for CRMP1 Gene at MOPED

Protein Expression for CRMP1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for CRMP1 Gene

Modification sites at PhosphoSitePlus
- Q14194
Modification sites at neXtProt
- NX_Q14194

Other Protein References for CRMP1 Gene

ENSEMBL proteins:

REFSEQ proteins:

Antibody Products

EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CRMP1

Browse R&D Systems for Antibodies

OriGene Antibodies for CRMP1
- TA306259
- TA306260
- TA306707
- TA321326
- TA323437
- TA323438
- TA323439
- TA346283
- TA346284
- TA346285
Custom Antibody Services

Novus Biologicals Antibodies for CRMP1

Abcam antibodies for CRMP1 (Q14194)

Browse Antibodies at Cloud-Clone Corp.

Invitrogen Antibodies for CRMP1

antibodies-online Antibodies for CRMP1: See all 114

GeneTex CRMP1 antibody for CRMP1

ProSci Antibodies for CRMP1
Custom Antibody Services

Santa Cruz Biotechnology (SCBT) Antibodies for CRMP1

Protein Products

Browse Purified and Recombinant Proteins at EMD Millipore

Browse R&D Systems for Human Recombinant Proteins

Browse Enzo Life Sciences for proteins

OriGene Purified Proteins for CRMP1
Search Origene for MassSpec and Protein Over-expression Lysates for CRMP1
Origene Custom Protein Services for CRMP1

GenScript Custom Purified and Recombinant Proteins Services for CRMP1

Novus Biologicals proteins and lysates for CRMP1

ProSpec Recombinant Proteins for CRMP1

Browse Proteins at Cloud-Clone Corp.

Search eBioscience for CRMP1 related proteins

antibodies-online Proteins for CRMP1: See all 13
Search antibodies-online for peptides

Search GeneTex for Proteins for CRMP1

Assay Products

Browse Kits and Assays available from EMD Millipore

GenScript Custom Assay Services for CRMP1

Browse Enzo Life Sciences for kits & assays

Browse Assay Kits at Cloud-Clone Corp.

Search eBioscience for CRMP1 related elisas

antibodies-online Kits for CRMP1: See all 3

No data available for DME Specific Peptides for CRMP1 Gene

Domains & Families for CRMP1 Gene

Protein Domains for CRMP1 Gene

InterPro:

Blocks:

ProtoNet:

Q14194

Suggested Antigen Peptide Sequences for CRMP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q14194

UniProtKB/Swiss-Prot:

DPYL1_HUMAN :

Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Family:

Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

No data available for Gene Families for CRMP1 Gene

Function for CRMP1 Gene

Molecular function for CRMP1 Gene

UniProtKB/Swiss-Prot Function:

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.

DPYL1_HUMAN,Q14194

Gene Ontology (GO) - Molecular Function for CRMP1 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016787	hydrolase activity	IEA	--

Phenotypes for CRMP1 Gene

MGI mutant phenotypes for CRMP1:

inferred from 2 alleles

GenomeRNAi human phenotypes for CRMP1:

Animal Models for CRMP1 Gene

MGI Knock Outs for CRMP1:

Crmp1 ^tm1Pako
Crmp1 ^tm1.1Swl

Animal Model Products

Taconic Biosciences Mouse Models for CRMP1
- Crmp1

ViGene Biosciences lentiviral particle packaged cDNA for CRMP1 gene
- LH808202
- LH887867
ViGene Biosciences ready-to-package AAV shRNAs for CRMP1 gene
- SH887867
- SH808202
Search ViGene Biosciences for CRMP1

CRISPR Products

OriGene CRISPR knockouts for CRMP1
- KN200483
- KN303842

Santa Cruz Biotechnology (SCBT) CRISPR for CRMP1

GenScript: Design CRISPR guide RNA sequences for CRMP1

miRNA for CRMP1 Gene

miRTarBase miRNAs that target CRMP1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CRMP1 Gene

Localization for CRMP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CRMP1 Gene

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes and the mitotic spindle during metaphase.

Q14194-DPYL1_HUMAN

Subcellular locations from

COMPARTMENTS

Jensen Localization Image for CRMP1 Gene

Compartment	Confidence
cytosol	5
cytoskeleton	4
nucleus	1
peroxisome	1

Gene Ontology (GO) - Cellular Components for CRMP1 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005815	microtubule organizing center	IEA	--

Pathways & Interactions for CRMP1 Gene

SuperPathways for CRMP1 Gene

More details on SuperPathways for CRMP1

	Superpath	Contained pathways
1	Developmental Biology	Axon guidance .64	Developmental Biology .64
2	Semaphorin interactions	Semaphorin interactions .40	CRMPs in Sema3A signaling 1
3	Guidance Cues and Growth Cone Motility	Guidance Cues and Growth Cone Motility 1
4	Semaphorin Signaling	Semaphorin Signaling 1

Pathways by source for CRMP1 Gene

4 Reactome pathways for CRMP1 Gene

2 Qiagen pathways for CRMP1 Gene

Interacting Proteins for CRMP1 Gene

http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000321606%0d%0a9606.ENSP00000318486%0d%0a9606.ENSP00000323194%0d%0a9606.ENSP00000288699%0d%0a9606.ENSP00000346671%0d%0a9606.ENSP00000331504%0d%0a — STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins: Q14194-DPYL1_HUMAN ENSP00000321606 for CRMP1 Gene via MINT STRING UniProtKB I2D

Symbol	External ID(s)	Details
VIM	P08670 ¹⁹ ⁴ ²¹ ENSP00000224237 ²⁰	MINT-3980404 MINT-8277004 MINT-3981786 STRING: ENSP00000224237 EBI-473101, EBI-353844 I2D: score=3
HTT	P42858 ¹⁹ ⁴ ²¹	MINT-3978065 MINT-3981306 EBI-473101, EBI-466029 I2D: score=3
AGR2	Q4JM47 ¹⁹ ²¹ O95994 ²¹	MINT-64307 I2D: score=3 I2D: score=1
AMFR	Q9UKV5 ¹⁹ ²¹ ENSP00000290649 ²⁰	MINT-8247685 STRING: ENSP00000290649 I2D: score=2
AXIN1	O15169 ¹⁹ ⁴ ²¹	MINT-64312 EBI-473101, EBI-710484 I2D: score=4

SIGNOR curated interactions for CRMP1 Gene

Is activated by:

CDK5
GSK3B

Gene Ontology (GO) - Biological Process for CRMP1 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006139	nucleobase-containing compound metabolic process	TAS	8973361
GO:0007399	nervous system development	TAS	8973361
GO:0048666	neuron development	IEA	--

Drugs & Compounds for CRMP1 Gene

No Compound Related Data Available

Drug Products

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CRMP1

Browse compounds at ApexBio

Transcripts for CRMP1 Gene

mRNA/cDNA for CRMP1 Gene

(4) REFSEQ mRNAs :

(12) Additional mRNA sequences :

(379) Selected AceView cDNA sequences:

(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CRMP1 Gene

Collapsin response mediator protein 1:

Hs.135270

Representative Sequences:

NM_001014809

CRISPR Products

OriGene CRISPR knockouts for CRMP1
- KN200483
- KN303842

Santa Cruz Biotechnology (SCBT) CRISPR for CRMP1

GenScript: Design CRISPR guide RNA sequences for CRMP1

miRNA Products

Search ViGene Biosciences for CRMP1

SwitchGear CRMP1 3' UTR sequence
Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhibitory RNA Products

Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for CRMP1
Browse OriGene Inhibitory RNA Products For CRMP1

ViGene Biosciences ready-to-package AAV shRNAs for CRMP1 gene
- SH887867
- SH808202

Search Santa Cruz Biotechnology (SCBT) for CRMP1 siRNA/shRNA

Clone Products

OriGene clones in human for CRMP1
OriGene ORF clones in human,mouse,rat for CRMP1
Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling

GenScript: cDNA clones in your preferred vector

Sino Biological Human cDNA Clone for CRMP1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat

Search Addgene for plasmids for CRMP1

Flow Cytometry Products

eBioscience FlowRNA Probe Sets

Alternative Splicing Database (ASD) splice patterns (SP) for CRMP1 Gene

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	·	5d	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15a	·	15b	^	16a	·	16b	·	16c
SP1:					-		-		-										-																				-				-
SP2:																			-																				-				-
SP3:													-		-		-		-
SP4:													-						-
SP5:					-		-		-
SP6:							-		-
SP7:																																											-
SP8:

Relevant External Links for CRMP1 Gene

GeneLoc Exon Structure for: CRMP1
ECgene alternative splicing isoforms for: CRMP1

Expression for CRMP1 Gene

mRNA expression in normal human tissues for CRMP1 Gene

mRNA expression by BioGPS for CRMP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Epiblast (Early Embryonic Tissues)
- Primordial Germ Cell Precursors Epiblast
- Intraembryonic Epiblast Cells Epiblast
- Epiblast-like cells (Hayashi K et. al. 2011)
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
- Cerebral Cortex
Gut Tube (Gastrointestinal Tract)
- Hindgut
- Foregut
- Midgut
Heart (Cardiovascular System)
- Endocardial Tube Cells Endocardium
- Cushion Mesenchymal Cells Endocardium
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
Neural Crest (Gastrulation Derivatives)
- PureStem 4D20.8, NCr-fac Progenitor
- PureStem SM30, NCr-fac & Meso-latp Progenitor
Gonad
- Primordial Germ Cell Precursors Epiblast
Eye (Sensory Organs)
- Retina
Inner Cell Mass (Early Embryonic Tissues)
- Induced pluripotent stem cell line 1
Lateral Plate Mesoderm (Gastrulation Derivatives)
- PureStem SM30, NCr-fac & Meso-latp Progenitor

Protein differential expression in normal tissues from HIPED for CRMP1 Gene

This gene is overexpressed in Fetal Brain (37.3), Brain (11.3), and Retina (8.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for CRMP1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CRMP1 Gene

Integrated proteomics: cell line protein expression from ProteomicsDB, MOPED and MaxQB for CRMP1 Gene

SOURCE GeneReport for Unigene cluster for CRMP1 Gene Hs.135270

mRNA Expression by UniProt/SwissProt for CRMP1 Gene

Q14194-DPYL1_HUMAN

Tissue specificity: Brain.

Protein tissue co-expression partners for CRMP1 Gene

Primer Products

OriGene qPCR primer pairs for CRMP1
- HP232913
OriGene qPCR primer pairs and template standards for CRMP1
- HK202217

No data available for mRNA differential expression in normal tissues for CRMP1 Gene

Orthologs for CRMP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for CRMP1 Gene

Organism	Taxonomy	Gene	Similarity	Type	Details
cow (Bos Taurus)	Mammalia	CRMP1 ³⁵	91.59 (n) 97.5 (a)		504250 NM_001192021.2 NP_001178950.1
cow (Bos Taurus)	Mammalia	CRMP1 ³⁶	96 (a)	OneToOne	6:105105248-105166798
dog (Canis familiaris)	Mammalia	CRMP1 ³⁵	91.16 (n) 97.23 (a)		479097 XM_536244.5 XP_536244.3
dog (Canis familiaris)	Mammalia	CRMP1 ³⁶	97 (a)	OneToOne	3:71010353-71082477
mouse (Mus musculus)	Mammalia	Crmp1 ³⁵	89.26 (n) 96.5 (a)		12933 NM_001136058.2 NP_001129530.1
		Crmp1 ¹⁶			37241940
		Crmp1 ³⁶	97 (a)	OneToOne	5:37242080-37292132
chimpanzee (Pan troglodytes)	Mammalia	CRMP1 ³⁵	99.51 (n) 99.42 (a)		750614 XM_003310238.2 XP_003310286.1
chimpanzee (Pan troglodytes)	Mammalia	CRMP1 ³⁶	98 (a)	OneToOne	4:5910584-5977748
rat (Rattus norvegicus)	Mammalia	Crmp1 ³⁵	88.13 (n) 96.78 (a)		25415 NM_012932.2 NP_037064.1
oppossum (Monodelphis domestica)	Mammalia	CRMP1 ³⁶	93 (a)	OneToOne	5:222830557-222909613
platypus (Ornithorhynchus anatinus)	Mammalia	CRMP1 ³⁶	95 (a)	OneToOne	Contig9603:1708-26657
chicken (Gallus gallus)	Aves	CRMP1 ³⁵	81.75 (n) 93.74 (a)		395156 NM_204495.1 NP_989826.1
chicken (Gallus gallus)	Aves	CRMP1B ³⁶	87 (a)	OneToOne	4:78786909-78831496
lizard (Anolis carolinensis)	Reptilia	CRMP1 ³⁶	85 (a)	OneToOne	5:80502695-80553498
tropical clawed frog (Silurana tropicalis)	Amphibia	crmp1 ³⁵	75.11 (n) 84.83 (a)		779767 NM_001078846.1 NP_001072314.1
zebrafish (Danio rerio)	Actinopterygii	crmp1 ³⁵	72.87 (n) 79.61 (a)		553756 NM_001020725.1 NP_001018561.1
zebrafish (Danio rerio)	Actinopterygii	crmp1 ³⁶	75 (a)	OneToOne	1:13228201-13249457
fruit fly (Drosophila melanogaster)	Insecta	CRMP ³⁷	45 (a)
worm (Caenorhabditis elegans)	Secernentea	dhp-1 ³⁷	46 (a)
		dhp-2 ³⁷	48 (a)
		unc-33 ³⁷	32 (a)

Species with no ortholog for CRMP1:

A. gosspyii yeast (Ashbya gossypii)
Actinobacteria (Mycobacterium tuberculosis)
African clawed frog (Xenopus laevis)
African malaria mosquito (Anopheles gambiae)
Alicante grape (Vitis vinifera)
alpha proteobacteria (Wolbachia pipientis)
amoeba (Dictyostelium discoideum)
Archea (Pyrococcus horikoshii)
baker's yeast (Saccharomyces cerevisiae)
barley (Hordeum vulgare)
beta proteobacteria (Neisseria meningitidis)
bread mold (Neurospora crassa)
Chromalveolata (Phytophthora infestans)
common water flea (Daphnia pulex)
corn (Zea mays)
E. coli (Escherichia coli)
filamentous fungi (Aspergillus nidulans)
Firmicute bacteria (Streptococcus pneumoniae)
fission yeast (Schizosaccharomyces pombe)
green algae (Chlamydomonas reinhardtii)
honey bee (Apis mellifera)
K. lactis yeast (Kluyveromyces lactis)
loblloly pine (Pinus taeda)
malaria parasite (Plasmodium falciparum)
medicago trunc (Medicago Truncatula)
moss (Physcomitrella patens)
orangutan (Pongo pygmaeus)
pig (Sus scrofa)
rainbow trout (Oncorhynchus mykiss)
rice (Oryza sativa)
rice blast fungus (Magnaporthe grisea)
schistosome parasite (Schistosoma mansoni)
sea anemone (Nematostella vectensis)
sea squirt (Ciona intestinalis)
sea squirt (Ciona savignyi)
sea urchin (Strongylocentrotus purpuratus)
sorghum (Sorghum bicolor)
soybean (Glycine max)
stem rust fungus (Puccinia graminis)
sugarcane (Saccharum officinarum)
thale cress (Arabidopsis thaliana)
tomato (Lycopersicon esculentum)
toxoplasmosis (Toxoplasma gondii)
Trichoplax (Trichoplax adhaerens)
wheat (Triticum aestivum)

Evolution for CRMP1 Gene

ENSEMBL:: Gene Tree for CRMP1 (if available)
TreeFam:: Gene Tree for CRMP1 (if available)

Paralogs for CRMP1 Gene

DPYSL5 ⁵
DPYSL3 ⁵
DPYSL2 ⁵
DPYS ⁵
DPYSL4 ⁵

(5) SIMAP similar genes for CRMP1 Gene using alignment to 4 proteins:

Variants for CRMP1 Gene

Sequence variations from dbSNP and Humsavar for CRMP1 Gene

SNP ID	Clin	Chr 04 pos	Sequence Context	Type
VAR_037745	-
rs12331	--	5,836,786(-)	ATGAC(A/C/G/T)GTCGT	reference, synonymous-codon
rs984576	--	5,850,411(+)	TTTGA(A/G)TGTCT	intron-variant
rs984577	--	5,850,632(+)	TTCAA(C/G)TGCCT	intron-variant
rs1383181	--	5,838,483(-)	cttCC(G/T)ACCAA	intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CRMP1 Gene

Variant ID	Type	Subtype	PubMed ID
esv34196	OTHER	Inversion	12058347
nsv829844	CNV	Gain	17160897
esv7115	CNV	Loss	19470904
esv2678074	CNV	Deletion	23128226
esv2726978	CNV	Deletion	23290073
esv2726979	CNV	Deletion	23290073
esv2279377	CNV	Deletion	18987734
nsv293630	CNV	Loss	16902084
nsv829845	CNV	Loss	17160897
nsv822449	CNV	Gain	20364138
esv29375	CNV	Gain+Loss	19812545

Variation tolerance for CRMP1 Gene

Residual Variation Intolerance Score: 8.01% of all genes are more intolerant (likely to be disease-causing)

Gene Damage Index Score: 6.40; 77.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CRMP1 Gene

HapMap Linkage Disequilibrium report: CRMP1
Human Gene Mutation Database (HGMD): CRMP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRMP1 Gene

Disorders for CRMP1 Gene

Relevant External Links for CRMP1

Genetic Association Database (GAD): CRMP1
Human Genome Epidemiology (HuGE) Navigator: CRMP1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:: CRMP1

No disorders were found for CRMP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CRMP1 Gene

Publications for CRMP1 Gene

A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution. (PMID: 8973361) Hamajima N. … Nonaka M. (Gene 1996) ² ³ ⁴ ²³ ⁶⁷
Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non- small cell lung cancer patients. (PMID: 19362386) Pan S.-H. … Yang P.-C. (Lung Cancer 2010) ³ ²³
Loss of collapsin response mediator Protein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII. (PMID: 19903856) Mukherjee J. … Guha A. (Cancer Res. 2009) ³ ²³
Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPalpha. (PMID: 18524846) Wu C.C. … Yang P.C. (Mol. Cancer Ther. 2008) ³ ²³
Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo. (PMID: 16611631) Cole A.R. … Sutherland C. (J. Biol. Chem. 2006) ³ ²³