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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CRISPLD2 Gene

protein-coding   GIFtS: 52
GCID: GC16P084853

Cysteine-Rich Secretory Protein LCCL Domain Containing 2

(Previous name: LCCL domain containing cysteine-rich secretory protein 2)
(Previous symbol: LCRISP2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cysteine-Rich Secretory Protein LCCL Domain Containing 21 2     CRISP-112 3
LCRISP21 2 3     CRISP112 3
LCCL Domain Containing Cysteine-Rich Secretory Protein 21 2     LCCL Domain-Containing Cysteine-Rich Secretory Protein 22 3
Cysteine-Rich Secretory Protein 112 3     Cysteine-Rich Secretory Protein LCCL Domain-Containing 22

External Ids:    HGNC: 252481   Entrez Gene: 837162   Ensembl: ENSG000001031967   OMIM: 6124345   UniProtKB: Q9H0B83   

Export aliases for CRISPLD2 gene to outside databases

Previous GC identifers: GC16P083412 GC16P070606


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CRISPLD2 Gene: 
CRISPLD2 (cysteine-rich secretory protein LCCL domain containing 2) is a protein-coding gene. Diseases associated with CRISPLD2 include cleft lip, and cleft palate. GO annotations related to this gene include heparin binding. An important paralog of this gene is CLEC18B.

UniProtKB/Swiss-Prot: CRLD2_HUMAN, Q9H0B8
Function: Promotes matrix assembly (By similarity)

Gene Wiki entry for CRISPLD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CRISPLD2 gene promoter:
         GR   ER-alpha   RP58   AP-1   RREB-1   HNF-4alpha1   FAC1   GR-alpha   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCRISPLD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CRISPLD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRISPLD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.1   Ensembl cytogenetic band:  16q24.1   HGNC cytogenetic band: 16q24.1

CRISPLD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRISPLD2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P084853:  view genomic region     (about GC identifiers)

Start:
84,853,587 bp from pter      End:
84,954,374 bp from pter
Size:
100,788 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CRLD2_HUMAN, Q9H0B8 (See protein sequence)
Recommended Name: Cysteine-rich secretory protein LCCL domain-containing 2 precursor  
Size: 497 amino acids; 55920 Da
Subunit: Binds to heparin, dermatan sulfate and chondroitin sulfate (By similarity)
Subcellular location: Secreted (By similarity)
Secondary accessions: D3DUM0 Q6P590 Q6UWH0 Q6UXC6 Q96IB1 Q96K61
Alternative splicing: 5 isoforms:  Q9H0B8-1   Q9H0B8-2   Q9H0B8-3   Q9H0B8-4   Q9H0B8-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CRISPLD2: NX_Q9H0B8

Explore proteomics data for CRISPLD2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H0B8

  • CRISPLD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CRISPLD2 Protein Expression
    REFSEQ proteins: NP_113664.1  
    ENSEMBL proteins: 
     ENSP00000262424   ENSP00000456554   ENSP00000457183   ENSP00000457655   ENSP00000454858  
     ENSP00000456952   ENSP00000457259   ENSP00000463171  

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    Novus Biologicals CRISPLD2 Protein
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    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CRISPLD2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0030133transport vesicle IDA--
    GO:0031012extracellular matrix IEA--

    CRISPLD2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR014044 CAP_domain
     IPR004043 LCCL
     IPR001283 Allrgn_V5/Tpx1
     IPR018244 Allrgn_V5/Tpx1_CS

    Graphical View of Domain Structure for InterPro Entry Q9H0B8

    ProtoNet protein and cluster: Q9H0B8

    1 Blocks protein domain: IPB001283 Allergen V5/Tpx-1 related

    UniProtKB/Swiss-Prot: CRLD2_HUMAN, Q9H0B8
    Similarity: Belongs to the CRISP family
    Similarity: Contains 2 LCCL domains
    Similarity: Contains 1 SCP domain


    CRISPLD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CRLD2_HUMAN, Q9H0B8
    Function: Promotes matrix assembly (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005539glycosaminoglycan binding ----
    GO:0008201heparin binding IEA--
         
    CRISPLD2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Crispld2 (no phenotypes)

    CRISPLD2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Crispld2tm1Lex for CRISPLD2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CRISPLD2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CRISPLD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CRISPLD2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CRISPLD2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CRISPLD2
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate CRISPLD2 (see all 27):
    hsa-miR-376b hsa-miR-4288 hsa-let-7a-2* hsa-miR-632 hsa-miR-548g hsa-miR-629* hsa-let-7g* hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmidCRISPLD2 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRISPLD2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CRISPLD2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CRISPLD2 (ENSP000002624244) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IQCB1ENSP000003115054STRING: ENSP00000311505
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030198extracellular matrix organization IEA--

    CRISPLD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CRISPLD2 (CRLD2)

    Search CenterWatch for drugs/clinical trials and news about CRISPLD2 / CRLD2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CRISPLD2 gene: 
    NM_031476.3  

    Unigene Cluster for CRISPLD2:

    Cysteine-rich secretory protein LCCL domain containing 2
    Hs.513779  [show with all ESTs]
    Unigene Representative Sequence: NM_031476
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262424(uc010vog.1 uc010voh.1) ENST00000566151 ENST00000567845
    ENST00000566431 ENST00000565561(uc002fik.4) ENST00000564567(uc002fin.4)
    ENST00000569090(uc002fil.2) ENST00000569262(uc002fim.2) ENST00000563066
    ENST00000566789 ENST00000566165
    miRNA
    Products:
         
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    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate CRISPLD2 (see all 27):
    hsa-miR-376b hsa-miR-4288 hsa-let-7a-2* hsa-miR-632 hsa-miR-548g hsa-miR-629* hsa-let-7g* hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmidCRISPLD2 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRISPLD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRISPLD2

    Additional mRNA sequence: 

    AK027395.1 AK056839.1 AK303887.1 AK308396.1 AL136861.1 AY358413.1 AY358790.1 BC007689.2 
    BC018643.2 BC063012.1 

    17 DOTS entries:

    DT.87016965  DT.40231085  DT.100717151  DT.101980538  DT.102842928  DT.120675550  DT.91715453  DT.120675546 
    DT.95142384  DT.102842927  DT.120675573  DT.91693739  DT.92430479  DT.120675552  DT.75156532  DT.91936301 
    DT.95113684 

    24/175 AceView cDNA sequences (see all 175):

    BQ003613 AW074528 BF222666 BC007689 AI581103 AI468764 AA954363 AA568584 
    CA415056 BE315250 AI972383 AK056839 CR593410 BU734411 BP345108 BE856161 
    CR606278 BQ010162 AI620252 CR596827 BQ003508 AI811893 BX357067 BM785441 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CRISPLD2 expression in normal human tissues (normalized intensities)      CRISPLD2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CRISPLD2 Expression
    About this image


    CRISPLD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 4 entries
             Umbilical cord blood-derived mesenchymal stem cells
             Human Umbillical Artery Smooth Muscle Cells (HUASMC)   
     
     Mesenchymal Stem Cells
             Umbilical cord blood-derived mesenchymal stem cells
             Human Umbilical Mesenchymal Stem Cells (HUMSC)   
     
     Smooth Muscle (Muscoskeletal System)    fully expand to see all 3 entries
             Human Umbillical Artery Smooth Muscle Cells (HUASMC)   
     
     Uncategorized (Uncategorized)    fully expand to see all 3 entries
             PureStem Progenitor W10
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Conventional Dendritic Cells II Spleen
             Umbilical cord blood-derived mesenchymal stem cells

    See CRISPLD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CRISPLD2

    SOURCE GeneReport for Unigene cluster: Hs.513779
        SABiosciences Custom PCR Arrays for CRISPLD2
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRISPLD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CRISPLD2 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Crispld21 , 5 cysteine-rich secretory protein LCCL domain containing more1, 5 79.08(n)1
    77.94(a)1
      8 (68.76 cM)5
    788921  NM_030209.31  NP_084485.11 
     1199924385 
    chicken
    (Gallus gallus)
    Aves CRISPLD21 cysteine-rich secretory protein LCCL domain containing more 72.7(n)
    73.64(a)
      415818  XM_414180.3  XP_414180.2 
    lizard
    (Anolis carolinensis)
    Reptilia CRISPLD26
    cysteine-rich secretory protein LCCL domain contai...
    71(a)
    1 ↔ 1
    GL343617.1(309783-334245)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005351491 cysteine-rich secretory protein LCCL domain-containing more 65.57(n)
    63.58(a)
      100535149  XM_003199017.1  XP_003199065.1 


    ENSEMBL Gene Tree for CRISPLD2 (if available)
    TreeFam Gene Tree for CRISPLD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CRISPLD2 gene
    CLEC18B2  CLEC18C2  PI162  GLIPR12  CRISP22  PI152  CRISP12  CRISPLD12  
    CRISP32  GLIPR1L12  CLEC18A2  GLIPR1L22  R3HDML2  
    4 SIMAP similar genes for CRISPLD2 using alignment to 6 protein entries:     CRLD2_HUMAN (see all proteins):
    PI15    R3HDML    CRISPLD1    CLEC18A

    CRISPLD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3055 SNPs in CRISPLD2 are shown (see all 3055)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118604741,2
    C,F,H--84851590(+) AGTGGC/TTCGAT 1 -- us2k110Minor allele frequency- T:0.13NS EA NA CSA WA 783
    rs1511527181,2
    --84851641(+) CCTCCC/TACCTC 1 -- us2k10--------
    rs1401764821,2
    --84851741(+) CTGAAC/TTCAAG 1 -- us2k10--------
    rs1453208951,2
    --84851786(+) CAGGCA/CTGAGC 1 -- us2k10--------
    rs1877394661,2
    --84851825(+) CTAACA/GCAGAT 1 -- us2k10--------
    rs1165278281,2
    C,F--84851846(+) CTTGGA/GTTTGT 1 -- us2k11Minor allele frequency- G:0.05WA 118
    rs727995411,2
    C,F--84851854(+) TGTCTT/GTTGTC 1 -- us2k11Minor allele frequency- G:0.05NA 120
    rs1913830731,2
    --84851872(+) GGACTC/GTTGTT 1 -- us2k10--------
    rs1821417481,2
    --84851958(+) TGGATA/GACTGC 1 -- us2k10--------
    rs1865313131,2
    --84852026(+) AAAGAG/TGAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CRISPLD2 (84853587 - 84954374 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for CRISPLD2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv457608CNV Loss19166990
    nsv457610CNV Loss19166990
    nsv907085CNV Gain21882294
    nsv907086CNV Gain21882294
    dgv2935n71CNV Gain21882294
    nsv457606CNV Gain19166990
    nsv907081CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612434    OMIM disorders: --

    2 diseases for CRISPLD2:    About MalaCards
    cleft lip    cleft palate

    2 diseases from the University of Copenhagen DISEASES database for CRISPLD2:
    Cleft lip     Cleft palate

    CRISPLD2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CRISPLD2
    Human Genome Epidemiology (HuGE) Navigator: CRISPLD2 (10 documents)

    Export disorders for CRISPLD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CRISPLD2 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with CRISPLD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. CRISPLD2: a novel NSCLP candidate gene. (PubMed id 17616516)1, 4, 9 Chiquet B.T....Hecht J.T. (2007)
    3. CRISPLD2 polymorphisms are associated with non-syndro mic cleft lip with or without cleft palate in a northern Chinese population. (PubMed id 20662919)1, 4 Shi J....Cao F. (2010)
    4. Testing reported associations of genetic risk factors for oral clefts in a large Irish study population. (PubMed id 19937600)1, 4 Carter T.C....Mills J.L. (2010)
    5. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    6. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    10. Nonsyndromic cleft lip and palate: CRISPLD genes and the folate gene pathway connection. (PubMed id 21254358)1 Chiquet B.T....Hecht J.T. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83716 HGNC: 25248 AceView: DKFZP434B044 Ensembl:ENSG00000103196 euGenes: HUgn83716
    ECgene: CRISPLD2 H-InvDB: CRISPLD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CRISPLD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CRISPLD2 gene:
    Search GeneIP for patents involving CRISPLD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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