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CRISP3 Gene

protein-coding GIFtS: 53
GCID: GC06M049741

Cysteine-Rich Secretory Protein 3

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Cysteine-Rich Secretory Protein 3¹ ²		CRS3²
Specific Granule Protein Of 28 KDa² ³		Cysteine-Rich Secretory Protein-3²
CRISP-3² ³		dJ442L6.3²
SGP28² ³		Specific Granule Protein (28 KDa)²
Aeg2²

External Ids:	HGNC: 16904¹	Entrez Gene: 10321²	Ensembl: ENSG00000096006⁷	UniProtKB: P54108³

Export aliases for CRISP3 gene to outside databases

Previous GC identifers: GC06M049696 GC06M049805 GC06M049425

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CRISP3 Gene:

CRISP3 (cysteine-rich secretory protein 3) is a protein-coding gene. Diseases associated with CRISP3 include vernal keratoconjunctivitis, and ectopic pregnancy. An important paralog of this gene is CLEC18B.

Gene Wiki entry for CRISP3 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000006.12 NC_018917.2 NT_007592.16

Regulatory elements:

Regulatory transcription factor binding sites in the CRISP3 gene promoter:
HNF-3beta Evi-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CRISP3 promoter sequence

Search Chromatin IP Primers for CRISP3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRISP3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.3 Ensembl cytogenetic band: 6p12.3 HGNC cytogenetic band: 6p12.3

CRISP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRISP3 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M049741: view genomic region (about GC identifiers)

Start:	49,695,089 bp from pter	End:	49,712,168 bp from pter
Size:	17,080 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CRIS3_HUMAN, P54108 (See protein sequence)

Recommended Name: Cysteine-rich secretory protein 3 precursor

Size: 245 amino acids; 27630 Da

Subunit: Interacts with A1BG

Sequence caution: Sequence=AAH69580.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=AAH69602.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG36185.1;

Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAA63984.1; Type=Erroneous

initiation; Note=Translation N-terminally extended; Sequence=CAA64527.1; Type=Erroneous initiation;

Note=Translation N-terminally extended;

Secondary accessions: A8K9S1 B2R8I8 Q15512 Q3MJ82 Q53FA9 Q5JW83 Q9H108

Alternative splicing: 3 isoforms: P54108-1 P54108-2 P54108-3

Explore the universe of human proteins at neXtProt for CRISP3: NX_P54108

Explore proteomics data for CRISP3 at MOPED

Post-translational modifications:

Glycosylation² at Asn239

Modification sites at PhosphoSitePlus

See CRISP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001177915.1 NP_006052.2

ENSEMBL proteins:

ENSP00000263045 ENSP00000360201 ENSP00000346636 ENSP00000389026 ENSP00000377274

ENSP00000410469

CRISP3 Human Recombinant Protein Products:

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	Novus Biologicals CRISP3 Lysate
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	Cloud-Clone Corp. Proteins for CRISP3

CRISP3 Antibody Products:

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	Novus Biologicals CRISP3 Antibody
	Abcam antibodies for CRISP3
	Cloud-Clone Corp. Antibodies for CRISP3
	Search ThermoFisher Antibodies for CRISP3
	LSBio Antibodies in human, mouse, rat for CRISP3

CRISP3 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for CRISP3
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CRISP3
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for CRISP3 Cloud-Clone Corp. CLIAs for CRISP3

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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5 InterPro protein domains:

IPR014044 CAP_domain

IPR001283 Allrgn_V5/Tpx1

IPR018244 Allrgn_V5/Tpx1_CS

IPR003582 ShKT_dom

IPR013871 Cysteine_rich_secretory

Graphical View of Domain Structure for InterPro Entry P54108

ProtoNet protein and cluster: P54108

2 Blocks protein domains:

IPB001283 Allergen V5/Tpx-1 related

IPB013871 Cysteine-rich secretory protein

UniProtKB/Swiss-Prot: CRIS3_HUMAN, P54108

Similarity: Belongs to the CRISP family

Similarity: Contains 1 SCP domain

Similarity: Contains 1 ShKT domain

CRISP3 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

CRISP3 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for CRISP3:

Lamellipodia cells

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Crisp1):

reproductive system

CRISP3 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Crisp1^tm1Pasc for CRISP3

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CRISP3

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CRISP3

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CRISP3

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CRISP3

miRNA Products:		miRTarBase miRNAs that target CRISP3: hsa-mir-1229-3p (MIRT036271)

		Block miRNA regulation of human, mouse, rat CRISP3 using miScript Target Protectors
		1 qRT-PCR Assays for microRNA that regulate CRISP3:
		hsa-miR-3149
		SwitchGear 3'UTR luciferase reporter plasmid: CRISP3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CRISP3
		Predesigned siRNA for gene silencing in human, mouse, rat CRISP3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CRISP3

Clone Products:		OriGene clones in human, mouse for CRISP3 (see all 9) OriGene ORF clones in mouse, rat for CRISP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): CRISP3 (NM_006061)
		Sino Biological Human cDNA Clone for CRISP3
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRISP3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRISP3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CRISP3
		Browse ESI BIO Cell Lines and PureStem Progenitors for CRISP3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRISP3

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

CRIS3_HUMAN, P54108: Secreted. Note=In neutrophils, localized in specific granules

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
extracellular	5
lysosome	1

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IDA	12009203
GO:0005578	proteinaceous extracellular matrix	NAS	12223513
GO:0042581	specific granule	IDA	12223513

CRISP3 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for CRISP3
Interactions:

GeneGlobe Interaction Network for CRISP3

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for CRISP3 (P54108³ ENSP00000263045⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
A1BG	P04217³, ENSP00000263100⁴	I2D: score=1 STRING: ENSP00000263100
BMPER	ENSP00000297161⁴	STRING: ENSP00000297161
CRIM1	ENSP00000280527⁴	STRING: ENSP00000280527
--	ENSP00000396664⁴	STRING: ENSP00000396664

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Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006952	defense response	NAS	12647793
GO:0045087	innate immune response	NAS	12223513

CRISP3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for CRISP3 (CRIS3)

1 Novoseek inferred chemical compound relationship for CRISP3 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
percoll	42	1	12223513 (1)

CRISP3 for compounds About GeneDecksing

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CRISP3 gene (2 alternative transcripts):

NM_001190986.1 NM_006061.2

Unigene Cluster for CRISP3:

Cysteine-rich secretory protein 3

Hs.404466 [show with all ESTs]

Unigene Representative Sequence: NM_001190986

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000263045 ENST00000371159 ENST00000354620 ENST00000433368(uc021zai.1 uc003ozs.3)

ENST00000393666 ENST00000423399

miRNA Products:		Block miRNA regulation of human, mouse, rat CRISP3 using miScript Target Protectors
		1 qRT-PCR Assays for microRNA that regulate CRISP3:
		hsa-miR-3149
		SwitchGear 3'UTR luciferase reporter plasmid: CRISP3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CRISP3
		Predesigned siRNA for gene silencing in human, mouse, rat CRISP3

Clone Products:		OriGene clones in human, mouse for CRISP3 (see all 9) OriGene ORF clones in mouse, rat for CRISP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): CRISP3 (NM_006061)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRISP3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRISP3

Primer Products:		OriGene qPCR primer pairs and template standards for CRISP3 OriGene qSTAR qPCR primer pairs in human, mouse for CRISP3
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat CRISP3
		QuantiTect SYBR Green Assays in human, mouse, rat CRISP3
		QuantiFast Probe-based Assays in human, mouse, rat CRISP3

Additional mRNA sequence:

AK223380.1 AK292786.1 AK313387.1 BC069580.1 BC069602.1 BC101539.1 X94323.1 X95240.1

7 DOTS entries:

DT.107746 DT.121376065 DT.121376073 DT.121376066 DT.121376071 DT.121308552 DT.85103119

Selected AceView cDNA sequences (see all 64):

NM_006061 X94323 BC069602 X95240 BC069580 AW075694 BE673586 AI791346

AI474434 BF897404 BF897378 BP334614 BP334549 AA888534 CN479307 BM993763

AW468294 BV198855 AW236196 BF446166 BE855975 AI400952 CA487317 AL703262

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CRISP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TGAGCCAAAT

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CRISP3 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 4) fully expand


Skeletal Muscle (Muscoskeletal System) fully expand to see all 2 entries
Myoblasts Mandibular Arch Muscles

Testis (Reproductive System)
Sertoli cells Seminiferous Tubules

Bone (Muscoskeletal System)
Bone Marrow

Esophagus (Gastrointestinal Tract)

CRISP3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

CRISP3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.404466

UniProtKB/Swiss-Prot: CRIS3_HUMAN, P54108

Tissue specificity: Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon

Custom PCR Arrays for CRISP3

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		QuantiFast Probe-based Assays in human, mouse, rat CRISP3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRISP3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CRISP3 gene from Selected species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Crisp1⁵	cysteine-rich secretory protein 1	--		17 (19.47 cM) 40293758
chicken (Gallus gallus)	Aves	--	Uncharacterized protein	56(a)	1 → many	3(108320648-108333075)
lizard (Anolis carolinensis)	Reptilia	-- -- (see all 3)	Uncharacterized protein (see all 3)	54(a) 51(a) (see all 3)	many ↔ many many ↔ many (see all 3)	1(121628264-121655431) 1(121596101-121610603)
tropical clawed frog (Xenopus tropicalis)	Amphibia	137721385²	--	79.16(n)		137721385
zebrafish (Danio rerio)	Actinopterygii	CRISP3⁶	cysteine-rich secretory protein 3	42(a)	1 → many	16(52339308-52358047) ENSDARG00000091103

ENSEMBL Gene Tree for CRISP3 (if available)
TreeFam Gene Tree for CRISP3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for CRISP3 gene

CLEC18B² CRISPLD2² CLEC18C² PI16² GLIPR1² CRISP2² PI15² CRISP1²

CRISPLD1² GLIPR1L1² CLEC18A² GLIPR1L2² R3HDML²

5 SIMAP similar genes for CRISP3 using alignment to 4 protein entries: CRIS3_HUMAN (see all proteins):

CRISP2 CRISP1 GLIPR1 GLIPR1L1 PI16

CRISP3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150130845^1,2		--	49694607(+)	`TTAACA/GGGCTC`	2	--	ds500¹		0	--	--	--	--
rs75341882^1,2	F	--	49694642(+)	`GGGAGG/AGTGGA`	2	--	ds500¹		1		WA	118
rs6902472^1,2	C,F,H	--	49694656(+)	`AAGTGA/GGATTG`	2	--	ds500¹		17		NS EA NA WA	2338
rs190021343^1,2		--	49694715(+)	`AGATCA/GTGAAT`	2	--	ds500¹		0	--	--	--	--
rs183331548^1,2		--	49694803(+)	`AAGAGA/GTGCAG`	2	--	ds500¹		0	--	--	--	--
rs619312^1,2	C,F,A,H	--	49694901(+)	`TACTGA/CAGTTT`	2	--	ds500¹		30		EA NA NS WA CSA	2544
rs114792206^1,2	C,F	--	49694909(+)	`TTTGAT/CACTGG`	2	--	ds500¹		1		WA	118
rs138656589^1,2		--	49694926(+)	`ATATCA/GATCTG`	2	--	ds500¹		0	--	--	--	--
rs149311207^1,2	C	--	49694959(+)	`ATTATC/TTGAAA`	2	--	ds500¹		0	--	--	--	--
rs696717^1,2	C,F,A	--	49695102(+)	`CAAGAC/TACTtt`	2	--	ut3¹ ese³		8		NA WA EA	504

HapMap Linkage Disequilibrium report for CRISP3 (49695089 - 49712168 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for CRISP3: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing CRISP3

DNA2.0 Custom Variant and Variant Library Synthesis for CRISP3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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17 diseases for CRISP3:
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vernal keratoconjunctivitis ectopic pregnancy otitis media keratoconjunctivitis

epididymitis sjogren's syndrome atopic dermatitis sinusitis

dermatitis inflammatory bowel disease prostate cancer hepatitis b

prostatitis ovarian cancer hepatitis adenocarcinoma

pancreatitis

CRISP3 for disorders About GeneDecksing

4 Novoseek inferred disease relationships for CRISP3 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
prostate cancer	18.6	11	12433721 (4), 17634540 (3), 16388501 (1)
inflammation	0	1	17665393 (1)
adenocarcinoma	0	1	12433721 (1)
cancer	0	3	16388501 (1), 12647793 (1), 12433721 (1)

Human Genome Epidemiology (HuGE) Navigator: CRISP3 (1 document)

Export disorders for CRISP3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CRISP3 gene, integrated from 10 sources (see all 56):
(articles sorted by number of sources associating them with CRISP3)

Utopia: connect your pdf to the dynamic
world of online information

The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. (PubMed id 8665901)^{1, 2, 3, 9} Kraetzschmar J.... Schleuning W.-D. (Eur. J. Biochem. 1996)
Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils. (PubMed id 12223513)^{1, 3, 9} Udby L....Kjeldsen L. (J. Leukoc. Biol. 2002)
Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. (PubMed id 15461460)^{1, 2, 9} Udby L.... Kjeldsen L. (Biochemistry 2004)
SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein. (PubMed id 8601434)^{1, 2, 9} Kjeldsen L.... Borregaard N. (FEBS Lett. 1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (Nature 2003)
Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland. (PubMed id 16388501)^{1, 9} Bjartell A....Udby L. (Prostate 2006)
Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy. (PubMed id 17634540)^{1, 9} Bjartell A.S....Scardino P.T. (Clin. Cancer Res. 2007)
Endometrial cysteine-rich secretory protein 3 is inhibited by human chorionic gonadotrophin, and is increased in the decidua of tubal ectopic pregnancy. (PubMed id 19282327)^{1, 9} Horne A.W....Critchley H.O. (Mol. Hum. Reprod. 2009)
Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis. (PubMed id 12647793)^{1, 9} Liao Q....Friess H. (Histol. Histopathol. 2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10321	HGNC: 16904	AceView: CRISP3	Ensembl:ENSG00000096006	euGenes: HUgn10321
ECgene: CRISP3	H-InvDB: CRISP3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CRISP3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CRISP3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CRISP3 gene:
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Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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Cysteine-Rich Secretory Protein 3

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