Aliases for CRISP3 Gene
External Ids for CRISP3 Gene
Previous GeneCards Identifiers for CRISP3 Gene
This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
GeneCards Summary for CRISP3 Gene
CRISP3 (Cysteine Rich Secretory Protein 3) is a Protein Coding gene. Diseases associated with CRISP3 include Prostate Cancer. Among its related pathways are Innate Immune System. An important paralog of this gene is CRISP2.