Aliases for CRISP3 Gene
Aliases for CRISP3 Gene
External Ids for CRISP3 Gene
- HGNC: 16904
- Entrez Gene: 10321
- Ensembl: ENSG00000096006
- UniProtKB: P54108
Previous GeneCards Identifiers for CRISP3 Gene
- GC06M049696
- GC06M049741
- GC06M049805
- GC06M049425
Summaries for CRISP3 Gene
-
This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
GeneCards Summary for CRISP3 Gene
CRISP3 (Cysteine Rich Secretory Protein 3) is a Protein Coding gene. Diseases associated with CRISP3 include Prostate Cancer. Among its related pathways are Innate Immune System. An important paralog of this gene is CRISP2.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CRISP3 Gene
Genomics for CRISP3 Gene
Regulatory Elements for CRISP3 Gene
Enhancers for CRISP3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G049645 | 1.3 | FANTOM5 ENCODE | 10.4 | +97.5 | 97502 | 3.4 | PKNOX1 ATF1 CREB3L1 ARNT E2F7 TCF12 ZNF766 ELK1 GATA2 KLF13 | RHAG LOC101927020 LOC101927048 CRISP3 C6orf141 CENPQ CRISP2 |
| GH06G049766 | 1 | ENCODE | 11.8 | -24.2 | -24240 | 4.5 | ATF1 MLX ARNT ZFP64 ARID4B DMAP1 YY1 TCF12 GATA2 CBX5 | LOC101927020 CRISP3 LOC101927048 MUT CRISP2 C6orf141 PGK2 |
| GH06G049666 | 0.9 | ENCODE | 11.2 | +77.1 | 77099 | 0.9 | HDAC1 HDGF PKNOX1 ATF1 TBL1XR1 ARNT NFRKB TCF12 CREM CEBPB | CRISP3 PGK2 C6orf141 RHAG CRISP2 |
| GH06G049668 | 0.8 | ENCODE | 11.2 | +76.3 | 76312 | 0.3 | ESRRA TBL1XR1 GTF2E2 ZNF175 CEBPG RAD21 CTBP1 GATA3 FOSL2 FOS | CRISP3 PGK2 CRISP2 LOC101927020 RHAG |
| GH06G049669 | 0.8 | ENCODE | 11.2 | +76.1 | 76053 | 0.2 | BRD4 GTF2E2 ZNF175 CEBPG ZNF644 RAD21 CTBP1 GATA3 FOSL2 FOS | CRISP3 PGK2 C6orf141 RHAG CRISP2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CRISP3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CRISP3 gene promoter:
Regulatory Element Products
Genomic Location for CRISP3 Gene
- Chromosome:
- 6
- Start:
- 49,727,376 bp from pter
- End:
- 49,744,455 bp from pter
- Size:
- 17,080 bases
- Orientation:
- Minus strand
Genomic View for CRISP3 Gene
Genes around CRISP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p12.3 by Ensembl
- 6p12.3 by Entrez Gene
- 6p12.3 by HGNC
CRISP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CRISP3 Gene
Proteins for CRISP3 Gene
-
Protein details for CRISP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P54108-CRIS3_HUMAN
- Recommended name:
- Cysteine-rich secretory protein 3
- Protein Accession:
- P54108
- A8K9S1
- B2R8I8
- Q15512
- Q3MJ82
- Q53FA9
- Q5JW83
- Q9H108
Protein attributes for CRISP3 Gene
- Size:
- 245 amino acids
- Molecular mass:
- 27630 Da
- Quaternary structure:
-
- Interacts with A1BG.
- SequenceCaution:
-
- Sequence=AAH69580.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH69602.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG36185.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA63984.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA64527.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for CRISP3 Gene
Post-translational modifications for CRISP3 Gene
Other Protein References for CRISP3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CRISP3 (CRISP-3)
-
Custom Antibody ServicesOriGene Antibodies for CRISP3
- Novus Biologicals Antibodies for CRISP3
-
Cloud-Clone Corp. Antibodies for CRISP3
- Invitrogen Antibodies for CRISP3
- antibodies-online Antibodies for CRISP3: See all 37
- Search GeneTex for Antibodies for CRISP3
-
Santa Cruz Biotechnology (SCBT) Antibodies for CRISP3
Protein Products
- R&D Systems Proteins and Enzymes for CRISP3 (CRISP-3)
-
OriGene Purified Proteins for CRISP3
- Search Origene for MassSpec and Protein Over-expression Lysates for CRISP3
- Origene Custom Protein Services for CRISP3
- ProSpec Recombinant Proteins for CRISP3
-
Cloud-Clone Corp. Proteins for CRISP3
- antibodies-online Proteins for CRISP3: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CRISP3
-
ProSci Proteins for CRISP3
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for CRISP3
-
Cloud-Clone Corp Assay Kits for CRISP3
- antibodies-online Kits for CRISP3: See all 9
No data available for DME Specific Peptides for CRISP3 Gene
Domains & Families for CRISP3 Gene
Protein Domains for CRISP3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CRISP3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P54108- Family:
-
- Belongs to the CRISP family.
No data available for Gene Families for CRISP3 Gene
Function for CRISP3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for CRISP3 Gene
- GenomeRNAi human phenotypes for CRISP3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CRISP3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CRISP3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CRISP3 gene
- Search ViGene Biosciences for CRISP3
CRISPR Products
-
OriGene CRISPR knockouts for CRISP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CRISP3
- GenScript: Design CRISPR guide RNA sequences for CRISP3
miRNA for CRISP3 Gene
- miRTarBase miRNAs that target CRISP3
miRNA Products
- Search ViGene Biosciences for CRISP3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CRISP3
- Browse OriGene Inhibitory RNA Products For CRISP3
-
ViGene Biosciences ready-to-package AAV shRNAs for CRISP3 gene
Clone Products
- Sino Biological Human cDNA Clone for CRISP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CRISP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRISP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CRISP3
-
ViGene Biosciences adenoviral particle packaged cDNA for CRISP3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CRISP3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CRISP3 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CRISP3 Gene
Localization for CRISP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CRISP3 Gene
- Secreted. Note=In neutrophils, localized in specific granules.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005578 | proteinaceous extracellular matrix | NAS | 12223513 |
| GO:0005615 | extracellular space | IDA | 16502470 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CRISP3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
Pathways by source for CRISP3 Gene
3 Reactome pathways for CRISP3 Gene
Interacting Proteins for CRISP3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006952 | defense response | NAS | 12647793 |
| GO:0043312 | neutrophil degranulation | TAS | -- |
| GO:0045087 | innate immune response | NAS | 12223513 |
No data available for SIGNOR curated interactions for CRISP3 Gene
Transcripts for CRISP3 Gene
mRNA/cDNA for CRISP3 Gene
- (2) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (64) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CRISP3 Gene
- Cysteine-rich secretory protein 3:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CRISP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CRISP3
- GenScript: Design CRISPR guide RNA sequences for CRISP3
miRNA Products
- Search ViGene Biosciences for CRISP3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CRISP3
- Browse OriGene Inhibitory RNA Products For CRISP3
-
ViGene Biosciences ready-to-package AAV shRNAs for CRISP3 gene
Clone Products
- Sino Biological Human cDNA Clone for CRISP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CRISP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRISP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for CRISP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CRISP3 Gene
This gene is overexpressed in Minor Salivary Gland (x37.2), Esophagus - Mucosa (x6.3), and Vagina (x4.7).
This gene is overexpressed in Cervix (29.0), Serum (7.8), and Saliva (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CRISP3 Gene
NURSA nuclear receptor signaling pathways regulating expression of CRISP3 Gene:
CRISP3SOURCE GeneReport for Unigene cluster for CRISP3 Gene:
Hs.404466mRNA Expression by UniProt/SwissProt for CRISP3 Gene:
P54108-CRIS3_HUMAN
Tissue specificity:
Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon.
Evidence on tissue expression from TISSUES for CRISP3 Gene
- Stomach(4.1)
- Bone(2.2)
- Bone marrow(2.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for CRISP3
-
OriGene qPCR primer pairs for CRISP3
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CRISP3 Gene
Orthologs for CRISP3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CRISP3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | LOC481834 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CRISP3 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Crisp1 35 |
|
OneToMany | |
| Crisp3 35 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | -- 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| zebrafish (Danio rerio) |
Actinopterygii | CRISP3 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| CSA.10077 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany |
- Species where no ortholog for CRISP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CRISP3 Gene
Paralogs for CRISP3 Gene
(5) SIMAP similar genes for CRISP3 Gene using alignment to 4 proteins:
Variants for CRISP3 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000128570 | -- | 49,730,240(+) | ATTGT(A/G)TGAGA | intron-variant | |
| rs1000204340 | -- | 49,739,207(+) | CCTGC(A/C)GAATT | intron-variant | |
| rs1001513815 | -- | 49,741,623(+) | TTTTT(G/T)TTTTT | intron-variant | |
| rs1001599520 | -- | 49,743,055(+) | ATGTA(A/T)CTGTG | intron-variant | |
| rs1001632082 | -- | 49,742,737(+) | CATTT(C/G)TTGAC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3397770 | CNV | insertion | 20981092 |
| esv3608949 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
75.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.15;
80.72% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CRISP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CRISP3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRISP3 Gene
Disorders for CRISP3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| prostate cancer |
|
Search CRISP3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CRISP3
No data available for UniProtKB/Swiss-Prot and Genatlas for CRISP3 Gene
Publications for CRISP3 Gene
- The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. (PMID: 8665901) Kraetzschmar J. … Schleuning W.-D. (Eur. J. Biochem. 1996) 2 3 4 22 64
- Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. (PMID: 15461460) Udby L. … Kjeldsen L. (Biochemistry 2004) 3 4 22 64
- Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils. (PMID: 12223513) Udby L. … Kjeldsen L. (J. Leukoc. Biol. 2002) 2 3 22 64
- SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein. (PMID: 8601434) Kjeldsen L. … Borregaard N. (FEBS Lett. 1996) 3 4 22 64
- Human CRISP-3 binds serum alpha(1)B-glycoprotein across species. (PMID: 20116414) Udby L. … Borregaard N. (Biochim. Biophys. Acta 2010) 3 22 64
Products for CRISP3 Gene
- R&D Systems Antibodies for CRISP3 (CRISP-3)
- R&D Systems Proteins and Enzymes for CRISP3 (CRISP-3)
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse cDNA Clones
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CRISP3
- Custom Assay ServicesOriGene ELISA Kits for CRISP3
- OriGene Purified Proteins for CRISP3
- Search Origene for MassSpec and Protein Over-expression Lysates for CRISP3
- Origene Custom Protein Services for CRISP3
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CRISP3
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- OriGene qPCR primer pairs and template standards for CRISP3
- OriGene qPCR primer pairs for CRISP3
- OriGene CRISPR knockouts for CRISP3
- OriGene ORF clones in human for CRISP3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for CRISP3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CRISP3
- GenScript Custom Assay Services for CRISP3
- GenScript Custom overexpressing Cell Line Services for CRISP3
- GenScript: Design CRISPR guide RNA sequences for CRISP3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
- GenScript Custom Peptide Services for CRISP3
- Sino Biological Human cDNA Clone for CRISP3
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CRISP3
- Novus Biologicals proteins and lysates for CRISP3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for CRISP3
- Cloud-Clone Corp. Antibodies for CRISP3
- Cloud-Clone Corp. Proteins for CRISP3
- Cloud-Clone Corp Assay Kits for CRISP3
- Invitrogen Antibodies for CRISP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for CRISP3: See all 37
- antibodies-online Kits for CRISP3: See all 9
- antibodies-online Proteins for CRISP3: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CRISP3
- Search GeneTex for Proteins for CRISP3
- ViGene Biosciences adenoviral particle packaged cDNA for CRISP3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CRISP3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CRISP3 gene
- Search ViGene Biosciences for CRISP3
- Santa Cruz Biotechnology (SCBT) Antibodies for CRISP3
- Search Santa Cruz Biotechnology (SCBT) for CRISP3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CRISP3
- Search for CRISP3 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CRISP3
- Horizon Cell Lines for CRISP3
- Cyagen custom Knockout/knockin (KOKI) mouse models for CRISP3
- VectorBuilder custom plasmid, inducible vectors for CRISP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CRISP3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CRISP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer