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CRIPT Gene

protein-coding   GIFtS: 52
GCID: GC02P046843

Cysteine-Rich PDZ-Binding Protein

  See CRIPT-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Cysteine-Rich PDZ-Binding Protein1 2
Cysteine-Rich Interactor Of PDZ Three2 3
Cysteine-Rich Interactor Of PDZ32 3
Postsynaptic Protein CRIPT2

External Ids:    HGNC: 143121   Entrez Gene: 94192   Ensembl: ENSG000001198787   OMIM: 6045945   UniProtKB: Q9P0213   
ORGUL members:         

Export aliases for CRIPT gene to outside databases

Previous GC identifers: GC02P046862 GC02P047013 GC02P046802 GC02P046818 GC02P046755 GC02P046697 GC02P046581


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CRIPT Gene:
CRIPT (cysteine-rich PDZ-binding protein) is a protein-coding gene. Diseases associated with CRIPT include short stature with microcephaly and distinctive facies. GO annotations related to this gene include PDZ domain binding and protein complex binding.

UniProtKB/Swiss-Prot: CRIPT_HUMAN, Q9P021
Function: Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses (By similarity)

Gene Wiki entry for CRIPT Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CRIPT gene promoter:
         AML1a   FOXF2   ATF-2   FOXO3   AP-2gamma   MEF-2A   AP-2beta   aMEF-2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCRIPT promoter sequence
   Search Chromatin IP Primers for CRIPT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRIPT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21   Ensembl cytogenetic band:  2p21   HGNC cytogenetic band: 2p21

CRIPT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRIPT gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P046843:  view genomic region     (about GC identifiers)

Start:
46,843,555 bp from pter      End:
46,852,881 bp from pter
Size:
9,327 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CRIPT_HUMAN, Q9P021 (See protein sequence)
Recommended Name: Cysteine-rich PDZ-binding protein  
Size: 101 amino acids; 11216 Da
Subunit: Interacts with TUBB1. Interacts strongly with the PDZ3 domain of members of the DLG4 family. Associates
with microtubules (By similarity). Interacts with DLG4

Explore the universe of human proteins at neXtProt for CRIPT: NX_Q9P021

Explore proteomics data for CRIPT at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CRIPT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_054890.1  
    ENSEMBL proteins: 
     ENSP00000238892  

    CRIPT Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Sino Biological Recombinant Protein for CRIPT
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for CRIPT
    Cloud-Clone Corp. Proteins for CRIPT

     
    Search eBioscience for Proteins for CRIPT 

     
    antibodies-online proteins for CRIPT (6 products) 

     
    antibodies-online peptides for CRIPT

    CRIPT Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of CRIPT
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    Novus Biologicals CRIPT Antibodies
    Abcam antibodies for CRIPT
    Cloud-Clone Corp. Antibodies for CRIPT
    ThermoFisher Antibodies for CRIPT
    antibodies-online antibodies for CRIPT (16 products) 

    CRIPT Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CRIPT
    Cloud-Clone Corp. CLIAs for CRIPT
    Search eBioscience for ELISAs for CRIPT 
    antibodies-online kits for CRIPT (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019367 PDZ-binding_CRIPT

    Graphical View of Domain Structure for InterPro Entry Q9P021

    ProtoNet protein and cluster: Q9P021

    UniProtKB/Swiss-Prot: CRIPT_HUMAN, Q9P021
    Similarity: Belongs to the CRIPT family


    Find genes that share domains with CRIPT           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CRIPT_HUMAN, Q9P021
    Function: Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11937501
    GO:0030165PDZ domain binding IEA--
    GO:0032403protein complex binding IEA--
         
    Find genes that share ontologies with CRIPT           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Cript):
     mortality/aging 

    Find genes that share phenotypes with CRIPT           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cripttm1(KOMP)Vlcg for CRIPT

       genOway: Develop your customized and physiologically relevant rodent model for CRIPT

    miRNA
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    Block miRNA regulation of human, mouse, rat CRIPT using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CRIPT (see all 18):
    hsa-miR-106a hsa-miR-138-2* hsa-miR-519a hsa-miR-93 hsa-miR-7-1* hsa-miR-532-5p hsa-miR-3662 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidCRIPT 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CRIPT
    Predesigned siRNA for gene silencing in human, mouse, rat CRIPT

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for CRIPT

    Clone
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    OriGene clones in human, mouse for CRIPT (see all 6)
    OriGene ORF clones in mouse, rat for CRIPT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CRIPT (NM_014171)
    Sino Biological Human cDNA Clone for CRIPT
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIPT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIPT

    Cell Line
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRIPT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CRIPT_HUMAN, Q9P021: Cytoplasm (By similarity). Cell junction, synapse (By similarity). Cell projection,
    dendritic spine (By similarity). Note=Colocalizes with DLG4 in asymmetric synapses (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    cytoskeleton2
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0014069postsynaptic density IEA--
    GO:0030054cell junction IEA--
    GO:0030425dendrite ----
    GO:0043025neuronal cell body IEA--

    Find genes that share ontologies with CRIPT           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CRIPT
    Interactions:

        GeneGlobe Interaction Network for CRIPT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for CRIPT (Q9P0211, 2, 3 ENSP000002388924) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG4P783521, 2, 3EBI-946968,EBI-80389 MINT-1901542 MINT-1901071 MINT-1901612 MINT-1900589 I2D: score=4 
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2866389 I2D: score=3 STRING: ENSP00000357292
    DLG1Q129593, ENSP000003457314I2D: score=2 STRING: ENSP00000345731
    DLG3Q927963, ENSP000003634804I2D: score=2 STRING: ENSP00000363480
    DLG2Q157003, ENSP000003652724I2D: score=1 STRING: ENSP00000365272
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031122cytoplasmic microtubule organization IEA--
    GO:0045184establishment of protein localization IEA--

    Find genes that share ontologies with CRIPT           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CRIPT



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CRIPT gene: 
    NM_014171.5  

    Unigene Cluster for CRIPT:

    Cysteine-rich PDZ-binding protein
    Hs.133998  [show with all ESTs]
    Unigene Representative Sequence: NM_014171
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486447 ENST00000238892(uc002rve.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CRIPT (see all 18):
    hsa-miR-106a hsa-miR-138-2* hsa-miR-519a hsa-miR-93 hsa-miR-7-1* hsa-miR-532-5p hsa-miR-3662 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidCRIPT 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CRIPT
    Predesigned siRNA for gene silencing in human, mouse, rat CRIPT
    Clone
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    OriGene clones in human, mouse for CRIPT (see all 6)
    OriGene ORF clones in mouse, rat for CRIPT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CRIPT (NM_014171)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIPT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIPT
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CRIPT
    OriGene qSTAR qPCR primer pairs in human, mouse for CRIPT
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CRIPT
      QuantiTect SYBR Green Assays in human, mouse, rat CRIPT
      QuantiFast Probe-based Assays in human, mouse, rat CRIPT

    Additional mRNA sequence: 

    AF161488.1 AK291298.1 BC006979.1 BC006980.1 BC018653.1 

    8 DOTS entries:

    DT.100794881  DT.113202  DT.121012453  DT.100794875  DT.121012513  DT.100794876  DT.97769824  DT.100794877 

    Selected AceView cDNA sequences (see all 188):

    BG149626 BQ267372 CK825319 AI912690 BU190150 AA461095 AI073516 AA283784 
    BF591360 AI572254 BQ231709 AW236961 BP349579 BQ004496 BX281639 AI201748 
    AA372934 AW292463 AI189393 BM460609 AI223792 AA165108 AI392760 AW196334 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CRIPT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATGAAAAT
    CRIPT Expression
    About this image

    CRIPT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CRIPT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.133998
        Custom PCR Arrays for CRIPT
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRIPT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CRIPT gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cript1 , 5 cysteine-rich PDZ-binding protein1, 5 90.76(n)1
    99.01(a)1
      17 (56.90 cM)5
    567241  NM_019936.31  NP_064320.11 
     870255505 
    chicken
    (Gallus gallus)
    Aves CRIPT1 cysteine-rich PDZ-binding protein 82.18(n)
    96.04(a)
      421412  NM_001031054.1  NP_001026225.1 
    lizard
    (Anolis carolinensis)
    Reptilia CRIPT6
    cysteine-rich PDZ-binding protein
    97(a)
    1 ↔ 1
    2(142822069-142827887)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.140042 Xenopus laevis transcribed sequence with strong similarity more 80.06(n)    BU907039.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cript1 cysteine-rich PDZ-binding protein 77.23(n)
    93.07(a)
      550592  NM_001017893.1  NP_001017893.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG45371 , 3 CG45371 60(a)3
    58.68(n)1
    62.5(a)1
      30E13
    343061  NM_001103665.21  NP_001097135.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C36B1.146
    Protein C36B1.14 (C36B1.14) mRNA, complete cds
    42(a)
    1 ↔ 1
    I(8730154-8730922) WBGene00044614
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G617801 AT1G61780 62.24(n)
    68.37(a)
      842475  NM_104860.4  NP_176371.1 
    rice
    (Oryza sativa)
    Liliopsida Os08g01908001 Os08g0190800 61.86(n)
    68.04(a)
      4344850  NM_001067703.2  NP_001061168.2 


    ENSEMBL Gene Tree for CRIPT (if available)
    TreeFam Gene Tree for CRIPT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CRIPT gene

    Find genes that share paralogs with CRIPT           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CRIPT
    PGOHUM00000239857


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CRIPT (see all 174)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75635771,2
    C,F,H--46846298(+) GAGGAG/AAAATT 1 -- int112Minor allele frequency- A:0.20NA NS EA WA 802
    rs1864952611,2
    --46846392(+) TATTTA/GCCTTC 1 -- int10--------
    rs75899081,2
    C,F--46846413(+) AATACA/GTATAG 1 -- int16Minor allele frequency- G:0.26WA CSA NA 245
    rs1379136001,2
    --46846627(+) CAGTAA/TCTTAA 1 -- int10--------
    rs1909786641,2
    --46846715(+) ATTATA/GTGTTA 1 -- int10--------
    rs1433744951,2
    C,F--46846770(+) GAAAGT/CGGTGG 2 /S syn11Minor allele frequency- C:0.00NA 4442
    rs739265351,2
    C--46846840(+) CCATCG/AATGGG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs2010029351,2
    --46846850(+) GTCACA/TTAAAT 1 -- int10--------
    rs1995105561,2
    --46846860(+) TTTCCC/TTCTTT 1 -- int10--------
    rs1826307091,2
    --46847170(+) CTAGCC/TTTATG 1 -- int10--------

    HapMap Linkage Disequilibrium report for CRIPT (46843555 - 46852881 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CRIPT:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv873997CNV Loss21882294
    nsv873996CNV Gain21882294
    dgv1181e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): CRIPT
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CRIPT
    DNA2.0 Custom Variant and Variant Library Synthesis for CRIPT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604594    OMIM disorders: --

    1 disease for CRIPT:    
    About MalaCards
    short stature with microcephaly and distinctive facies


    Find genes that share disorders with CRIPT           About GenesLikeMe

    Genetic Association Database (GAD): CRIPT
    Human Genome Epidemiology (HuGE) Navigator: CRIPT (2 documents)

    Export disorders for CRIPT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CRIPT gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with CRIPT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)1, 4 Saus E....Estivill X. (J Psychiatr Res 2010)
    2. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    3. The interaction between PSD-95 and Ca2+/calmodulin is enhanced by PDZ-binding proteins. (PubMed id 16091592)1, 3 Fukunaga Y....Miyazawa A. (J. Biochem. 2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The PDZ1 domain of SAP90. Characterization of structure and binding. (PubMed id 11744724)1, 3 Piserchio A.... Mierke D.F. (J. Biol. Chem. 2002)
    6. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    7. Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95. (PubMed id 10570482)1, 3 Passafaro M....Sheng M. (Nat. Neurosci. 1999)
    8. CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90. (PubMed id 9581762)1, 3 Niethammer M....Sheng M. (Neuron 1998)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9419 HGNC: 14312 AceView: CRIPT Ensembl:ENSG00000119878 euGenes: HUgn9419
    ECgene: CRIPT H-InvDB: CRIPT

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CRIPT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for CRIPT gene:
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