Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CRIP1 Gene

protein-coding   GIFtS: 50
GCID: GC14P105952

cysteine-rich protein 1 (intestinal)
 Explore 6 diseases affiliated with
CRIP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CRIP1    

Aliases
for CRIP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cysteine-Rich Protein 1 (Intestinal)1 2     CRP-12 3
CRIP1 2 3 5     CRP12 3
Cysteine-Rich Heart Protein2 3     Cysteine-Rich Protein 12
Cysteine-Rich Intestinal Protein2 3     HCRHP1
CRHP2 3     

External Ids:    HGNC: 23601   Entrez Gene: 13962   Ensembl: ENSG000002131457   OMIM: 1238755   UniProtKB: P502383   

Export aliases for CRIP1 gene to outside databases

Previous GC identifers: GC22P021804 GC14P099944 GC14P103925 GC14P105024 GC14P086151


Summaries
for CRIP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CRIP1:
Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include
cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM
180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins,
1991 (PubMed 1946385)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238
Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein

Gene Wiki entry for CRIP1


Genomic Views
for CRIP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CRIP1 gene promoter:
         NF-1/L   NF-1   NRSF form 1   MyoD   NF-kappaB1   NF-kappaB   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CRIP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CRIP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33   Ensembl cytogenetic band:  14q32.33   HGNC cytogenetic band: 14q32.33

CRIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRIP1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P105952:  view genomic region     (about GC identifiers)

Start:
 105,952,654 bp from pter      End:
 105,955,284 bp from pter
Size:
 2,631 bases      Orientation:
 plus strand

Proteins
for CRIP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238 (See protein sequence)
Recommended Name: Cysteine-rich protein 1  
Size: 77 amino acids; 8533 Da
Secondary accessions: H3BPI2 Q13628 Q53XY7 Q96J34

Explore the universe of human proteins at neXtProt for CRIP1: NX_P50238

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P50238

    • CRIP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001302.1  
    ENSEMBL proteins: 
     ENSP00000332449   ENSP00000386340   ENSP00000376315  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: CRIP1
    OriGene Protein Over-expression Lysate: CRIP1
    OriGene Custom Protein Services for CRIP1 
    GenScript Custom Purified and Recombinant Proteins Services for CRIP1
    Novus Biologicals CRIP1 Protein
    Novus Biologicals CRIP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CRIP1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA9126610


    CRIP1 for ontologies           About GeneDecksing



    CRIP1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CRIP1 
    GenScript Custom Superior Antibodies Services for CRIP1
    Novus Biologicals CRIP1 Antibody
    Search for Antibodies for CRIP1 at Abcam  
    Uscn Antibodies for CRIP1
    ThermoFisher Antibody for CRIP1

    Assay Products for CRIP1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CRIP1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CRIP1

    Protein Domains /
    Families
    for CRIP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CRIP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry P50238

    ProtoNet protein and cluster: P50238

    1 Blocks protein family: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238
    Similarity: Contains 1 LIM zinc-binding domain


    Function
    for CRIP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238
    Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein

         Genatlas biochemistry entry for CRIP1:
    cysteine-rich heart protein 1,playing a role in processes of cellular repair (located in a region of multiple
    breakpoint)

    miRNA
    Products:            		 OriGene 3'-UTR Clone: CRIP1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CRIP1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CRIP1:
    hsa-miR-221*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CRIP1 (see all 7)
    OriGene shRNA RFP: CRIP1
    OriGene siRNA: CRIP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRIP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CRIP1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CRIP1 (NM_001311)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CRIP1
    LifeMap BioReagents: cell line associated with CRIP1: PureStem Progenitor E68

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CRIP1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003680AT DNA binding IDA--
    GO:0008270zinc ion binding IDA9126610
    GO:0008301DNA binding, bending IDA--
    GO:0042277peptide binding IDA18670594


    CRIP1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for CRIP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CRIP1

    5/6 Interacting proteins for CRIP1 (P502383) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929053I2D: score=5 
    SMYD3Q9H7B43I2D: score=5 
    SH3GL3Q999633I2D: score=4 
    GPRASP1Q5JY773I2D: score=3 
    HAP1P542573I2D: score=3 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IDA--
    GO:0006955immune response IEP--
    GO:0007507heart development TAS7999070
    GO:0008283cell proliferation TAS9126610
    GO:0010033response to organic substance IEP17486081


    CRIP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CRIP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CRIP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CRIP1
    3 Novoseek chemical compound relationships for CRIP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 57.8 12 1407754 (2), 7999070 (1), 11078733 (1), 17526766 (1) (see all 7)
    histidine 41.8 1 8286377 (1)
    cysteine 16.4 6 8286377 (1), 2115670 (1)

    Search CenterWatch for drugs/clinical trials and news about CRIP1 

    Transcripts
    for CRIP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CRIP1 gene: 
    NM_001311.4  

    Unigene Cluster for CRIP1:

    Cysteine-rich protein 1 (intestinal)
    Hs.70327  [show with all ESTs]
    Unigene Representative Sequence: BE745323
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496700 ENST00000330233 ENST00000409393 ENST00000392531(uc001yri.4)
    ENST00000460900 ENST00000461556

    miRNA
    Products:             		 OriGene 3'-UTR Clone: CRIP1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CRIP1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CRIP1:
    hsa-miR-221*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CRIP1 (see all 7)
    OriGene shRNA RFP: CRIP1
    OriGene siRNA: CRIP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRIP1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CRIP1 (NM_001311)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRIP1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CRIP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRIP1

    Additional cDNA sequence: 

    BC002738.2 BT007181.1 U09770.1 U58630.1 

    6 DOTS entries:

    DT.313573  DT.95221057  DT.95245299  DT.100780551  DT.100026177  DT.100026178 

    24/256 AceView cDNA sequences (see all 256):

    BM743922 BX446407 BM742522 BM770333 AA910827 BM771015 BX377075 BM552451 
    BM770223 BM768102 BM743871 CR621976 BM765389 BX248283 BM819466 BM767307 
    BQ232747 BX339688 BM770288 CR618931 BM770801 BX358586 CR623408 BM461601 

    GeneLoc Exon Structure


    Expression
    for CRIP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CRIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTGGGCCTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CRIP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyAfferent ArterioleJuxtaglomerular CellsKidney, Smooth Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 10/11 LifeMap Cells (see all 11) 
    NameCategory
    PureStem™ progenitor E68 (Embryonic Progenitor Cell)
    PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)Intermediate Mesoderm, Kidney
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)Lateral Plate Mesoderm, Neural Crest
    PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)
    N2/LSB induced-cells (Generation of midbra...)
    Definitive endoderm-like cells (A scalable, suspensi...)
    HyStem+BMP4-induced MEL2 cells (HyStem+BMP4 inductio...)Bone

    See CRIP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CRIP1

    SOURCE GeneReport for Unigene cluster: Hs.70327
        SABiosciences Custom PCR Arrays for CRIP1
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRIP1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CRIP1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRIP1
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CRIP1

    Orthologs
    for CRIP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CRIP1 gene from 5/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CRIP26
    		 Uncharacterized protein
    		 35(a)
    		 1 → many
    		 8(4010725-4024472)
    lizard
    (Anolis carolinensis)    		 Reptilia CRIP16
    		 --
    		 90(a)
    		 1 → many
    		 4(73956478-73967281)
    zebrafish
    (Danio rerio)    		 Actinopterygii crip11 cysteine-rich protein 1 78.35(n)
    89.61(a)    		   541319  NM_001166582.1  NP_001160054.1 
    honey bee
    (Apis mellifera)    		 Insecta --
    		 --
    		 78(a)
    		 1 → many
    		 Group4.19(319516-327444)
    worm
    (Caenorhabditis elegans)    		 Secernentea B0496.73
    valv-11    		 Protein VALV-11 74(a)3
    66.22(n)1
    77.33(a)1    		   IV(7444855-7445654)3
    1820101  NM_068786.41  NP_501187.11 


    ENSEMBL Gene Tree for CRIP1 (if available)
    TreeFam Gene Tree for CRIP1 (if available) 

    Paralogs
    for CRIP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CRIP1 gene
    CSRP22  CSRP12  CRIP22  ENSG000002573412  CRIP32  CSRP32  
    18/27 SIMAP similar genes for CRIP1 using alignment to 3 protein entries:     CRIP1_HUMAN (see all proteins) (see all similar genes):
    CRIP2    CRIP3    DKFZp686M148    LASP1    CSRP1    ABLIM1
    MICAL3    NRAP    PXN    PDLIM5    DKFZp686P2249    LIMK1
    LIMS1    MICALL2    AAG11    ABLIM2    FHL2    FBLIM1

    CRIP1 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for CRIP1
    PGOHUM00000245159 PGOHUM00000246546 PGOHUM00000237942 PGOHUM00000237964


    Genomic Variants
    for CRIP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/81 NCBI SNPs in CRIP1 are shown (see all 81)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1160325051,2
    		F,--105951289(+) GAGGAC/GAAGGA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs352030321,2
    		C,F,--105951319(+) TGCCCT/CGGCTA 1 -- us2k15Minor allele frequency- C:0.14NA 128
    rs1861628641,2
    		--105951400(+) TATGGA/GCGGAC 1 -- us2k10--------
    rs1907167011,2
    		--105951401(+) ATGGGC/TGGACA 1 -- us2k10--------
    rs1165057731,2
    		C,F,--105951435(+) GCTCGC/AGGGGA 1 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1815276131,2
    		--105951484(+) TCCACA/GGGCAC 1 -- us2k10--------
    rs733620691,2
    		C,--105951537(+) CACCCA/GGAGCA 1 -- us2k13Minor allele frequency- G:0.44WA CSA 121
    rs344480961,2
    		C,F,H--105951611(+) CCCCAG/TGGAAA 1 -- us2k12Minor allele frequency- T:0.01NS 280
    rs1115407351,2
    		C,--105951725(+) TCCCAC/TGATGC 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1171769921,2
    		F,--105951804(+) AGTGGG/CGGTTC 1 -- us2k11Minor allele frequency- C:0.04NA 120

    HapMap Linkage Disequilibrium report for CRIP1 (105952654 - 105955284 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CRIP1
         1 CNV: 29968

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRIP1
    DNA2.0 Custom Variant and Variant Library Synthesis for CRIP1

    Disorders / Diseases
    for CRIP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CRIP1 for disorders           About GeneDecksing

    OMIM gene information: 123875    OMIM disorders: --

    6 diseases for CRIP1:    About MalaCards
    situs inversus    hermaphroditism    pharyngitis    prostate cancer
    prostatitis    neuronitis


    Export disorders for CRIP1 gene to outside databases

    Publications
    for CRIP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CRIP1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with CRIP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Mapping of the human cysteine-rich intestinal protein gene CRIP1 to the human chromosomal segment 7q11.23. (PubMed id 9480758)1, 3, 9 Garcia-Barcelo M....Waye M.M. (1998)
    2. Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells. (PubMed id 9126610)1, 2, 9 Khoo C.... Cousins R.J. (1997)
    3. Isolation and characterization of a cDNA that codes for a LIM- containing protein which is developmentally regulated in heart. (PubMed id 7999070)1, 2, 9 Tsui S.K.W.... Waye M.M.Y. (1994)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate. (PubMed id 9507743)1, 9 Dube J.Y....Tremblay R.R. (1998)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. CRIP1 expression is correlated with a favorable outcom e and less metastases in osteosarcoma patients. (PubMed id 22202598)1 Baumhoer D....Nathrath M. (2011)
    9. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    10. Identification and rational redesign of peptide ligan ds to CRIP1, a novel biomarker for cancers. (PubMed id 18670594)1 Hao J....Basilion J.P. (2008)

    External Searches for CRIP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CRIP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1396 HGNC: 2360 AceView: CRIP1andC14orf80 Ensembl:ENSG00000213145 euGenes: HUgn1396
    ECgene: CRIP1 H-InvDB: CRIP1

    Other Databases showing CRIP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CRIP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CRIP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CRIP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CRIP1 gene:
    Search GeneIP for patents involving CRIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for CRIP1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for CRIP1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CRIP1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CRIP1  
     OriGene Protein Over-expression Lysate for CRIP1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for CRIP1   OriGene 3'-UTR Clone for CRIP1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CRIP1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for CRIP1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CRIP1   OriGene Custom Protein Services for CRIP1  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CRIP1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CRIP1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CRIP1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CRIP1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CRIP1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
     GenScript Custom Purified and Recombinant Proteins Services for CRIP1 GenScript cDNA clones with any tag delivered in your preferred vector for CRIP1
     GenScript Custom Assay Services for CRIP1 GenScript Custom Superior Antibodies Services for CRIP1
     GenScript Custom overexpressing Cell Line Services for CRIP1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CRIP1 promoter
     Search Chromatin IP Primers for CRIP1
     RT2 qPCR Primer Assay in human, mouse, rat CRIP1
     Search GNC Networks for CRIP1
     SABiosciences Custom PCR Arrays for CRIP1
     Search Tocris compounds for CRIP1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CRIP1 antibodies
     CRIP1 proteins
     CRIP1 lysates
     Search for Antibodies for CRIP1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for CRIP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     CRIP1 Proteins, Antibodies, CLIAs, and ELISAs
     Cell Line associated with CRIP1: PureStem Progenitor E68
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CRIP1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for CRIP1
     SwitchGear Promoter luciferase reporter plasmids for CRIP1
     ThermoFisher Antibody for CRIP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      CRIP1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4