Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CRIP1 Gene

protein-coding   GIFtS: 52
GCID: GC14P105952

Cysteine-Rich Protein 1 (Intestinal)

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cysteine-Rich Protein 1 (Intestinal)1 2     CRP-12 3
CRIP2 3 5     CRP12 3
Cysteine-Rich Heart Protein2 3     Cysteine-Rich Protein 12
Cysteine-Rich Intestinal Protein2 3     hCRHP3
CRHP2 3     

External Ids:    HGNC: 23601   Entrez Gene: 13962   Ensembl: ENSG000002131457   OMIM: 1238755   UniProtKB: P502383   

Export aliases for CRIP1 gene to outside databases

Previous GC identifers: GC22P021804 GC14P099944 GC14P103925 GC14P105024 GC14P086151


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CRIP1 Gene:
Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which
include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2
(RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport
(Hempe and Cousins, 1991 (PubMed 1946385)).(supplied by OMIM, Mar 2008)

GeneCards Summary for CRIP1 Gene:
CRIP1 (cysteine-rich protein 1 (intestinal)) is a protein-coding gene. GO annotations related to this gene include DNA binding, bending and AT DNA binding. An important paralog of this gene is CSRP2.

UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238
Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein

Gene Wiki entry for CRIP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the CRIP1 gene promoter:
         NF-1/L   NF-1   NRSF form 1   MyoD   NF-kappaB1   NF-kappaB   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCRIP1 promoter sequence
   Search Chromatin IP Primers for CRIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33   Ensembl cytogenetic band:  14q32.33   HGNC cytogenetic band: 14q32.33

CRIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CRIP1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P105952:  view genomic region     (about GC identifiers)

Start:
105,952,654 bp from pter      End:
105,955,284 bp from pter
Size:
2,631 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238 (See protein sequence)
Recommended Name: Cysteine-rich protein 1  
Size: 77 amino acids; 8533 Da
Secondary accessions: H3BPI2 Q13628 Q53XY7 Q96J34

Explore the universe of human proteins at neXtProt for CRIP1: NX_P50238

Explore proteomics data for CRIP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys9
  • Modification sites at PhosphoSitePlus

  • See CRIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001302.1  
    ENSEMBL proteins: 
     ENSP00000332449   ENSP00000386340   ENSP00000376315  

    CRIP1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CRIP1
    OriGene Protein Over-expression Lysate for CRIP1
    OriGene MassSpec for CRIP1
    OriGene Custom Protein Services for CRIP1
    GenScript Custom Purified and Recombinant Proteins Services for CRIP1
    Novus Biologicals CRIP1 Proteins
    Novus Biologicals CRIP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CRIP1

     
    Search eBioscience for Proteins for CRIP1 

     
    antibodies-online proteins for CRIP1 (6 products) 

     
    antibodies-online peptides for CRIP1

    CRIP1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CRIP1
    Novus Biologicals CRIP1 Antibody
    Abcam antibodies for CRIP1
    Cloud-Clone Corp. Antibodies for CRIP1
    ThermoFisher Antibody for CRIP1
    antibodies-online antibodies for CRIP1 (11 products) 

    CRIP1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CRIP1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CRIP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CRIP1
    Cloud-Clone Corp. CLIAs for CRIP1
    Search eBioscience for ELISAs for CRIP1 
    antibodies-online kits for CRIP1 (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry P50238

    ProtoNet protein and cluster: P50238

    1 Blocks protein domain: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: CRIP1_HUMAN, P50238
    Similarity: Contains 1 LIM zinc-binding domain


    Find genes that share domains with CRIP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CRIP1_HUMAN, P50238
    Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein

         Genatlas biochemistry entry for CRIP1:
    cysteine-rich heart protein 1,playing a role in processes of cellular repair (located in a region of multiple
    breakpoint)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003680AT DNA binding IDA--
    GO:0008270zinc ion binding IDA9126610
    GO:0008301DNA binding, bending IDA--
    GO:0042277peptide binding IDA18670594
         
    Find genes that share ontologies with CRIP1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CRIP1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CRIP1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CRIP1:
    hsa-miR-221*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CRIP1
    Predesigned siRNA for gene silencing in human, mouse, rat CRIP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CRIP1

    Clone
    Products:
         
    OriGene clones in human, mouse for CRIP1 (see all 6)
    OriGene ORF clones in mouse, rat for CRIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CRIP1 (NM_001311)
    Sino Biological Human cDNA Clone for CRIP1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CRIP1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CRIP1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with CRIP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CRIP1
    Interactions:

        Search GeneGlobe Interaction Network for CRIP1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for CRIP1 (P502383 ENSP000003324494) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3GL3Q999633, ENSP000003913724I2D: score=4 STRING: ENSP00000391372
    COPS5Q929053I2D: score=5 
    SMYD3Q9H7B43I2D: score=5 
    GPRASP1Q5JY773I2D: score=3 
    HAP1P542573I2D: score=3 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response IEP--
    GO:0007507heart development TAS7999070
    GO:0008283cell proliferation TAS9126610
    GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage IDA--
    GO:0010033response to organic substance IEP17486081

    Find genes that share ontologies with CRIP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CRIP1

    3 Novoseek inferred chemical compound relationships for CRIP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 57.8 12 1407754 (2), 7999070 (1), 11078733 (1), 17526766 (1) (see all 7)
    histidine 41.8 1 8286377 (1)
    cysteine 16.4 6 8286377 (1), 2115670 (1)



    Find genes that share compounds with CRIP1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CRIP1 gene: 
    NM_001311.4  

    Unigene Cluster for CRIP1:

    Cysteine-rich protein 1 (intestinal)
    Hs.70327  [show with all ESTs]
    Unigene Representative Sequence: BE745323
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496700 ENST00000330233 ENST00000409393 ENST00000392531(uc001yri.4)
    ENST00000460900 ENST00000461556
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CRIP1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CRIP1:
    hsa-miR-221*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CRIP1
    Predesigned siRNA for gene silencing in human, mouse, rat CRIP1
    Clone
    Products:
         
    OriGene clones in human, mouse for CRIP1 (see all 6)
    OriGene ORF clones in mouse, rat for CRIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CRIP1 (NM_001311)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CRIP1
    OriGene qSTAR qPCR primer pairs in human, mouse for CRIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CRIP1
      QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
      QuantiFast Probe-based Assays in human, mouse, rat CRIP1

    Additional mRNA sequence: 

    BC002738.2 BT007181.1 U09770.1 U58630.1 

    6 DOTS entries:

    DT.313573  DT.95221057  DT.95245299  DT.100780551  DT.100026177  DT.100026178 

    Selected AceView cDNA sequences (see all 256):

    BE873246 BX248074 BM742569 C00425 BM767307 BI160461 BQ128340 BM743922 
    CR616658 BM766855 BM770223 BM770333 BM552451 BM768102 BM771535 BM771015 
    CR602316 BX377075 BX446407 BM743871 BM767233 BM765744 BM771458 BM770272 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CRIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTGGGCCTA
    CRIP1 Expression
    About this image


    CRIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Kidney (Urinary System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Thymus (Hematopoietic System)
             Thymus
    CRIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CRIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.70327
        Custom PCR Arrays for CRIP1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CRIP1
    OriGene qSTAR qPCR primer pairs in human, mouse for CRIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CRIP1
    QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
    QuantiFast Probe-based Assays in human, mouse, rat CRIP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for CRIP1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Crip11 , 5 cysteine-rich protein 1 (intestinal)1, 5 88.74(n)1
    97.4(a)1
      12 (61.59 cM)5
    129251  NM_007763.31  NP_031789.11 
     1131520125 
    chicken
    (Gallus gallus)
    Aves CRIP11 cysteine-rich protein 1 (intestinal) 84.85(n)
    90.91(a)
      101747696  XM_004943153.1  XP_004943210.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    90(a)
    1 → many
    4(73956323-73967777)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia crip11 cysteine-rich protein 1 (intestinal) 76.62(n)
    84.42(a)
      100125153  NM_001171648.1  NP_001165119.1 
    zebrafish
    (Danio rerio)
    Actinopterygii crip11 cysteine-rich protein 1 78.35(n)
    89.61(a)
      541319  NM_001166582.1  NP_001160054.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0496.73
    valv-11
    valv-11 74(a)3
    66.22(n)1
    77.33(a)1
      IV(7444855-7445654)3
    1820101  NM_068786.51  NP_501187.11 


    ENSEMBL Gene Tree for CRIP1 (if available)
    TreeFam Gene Tree for CRIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CRIP1 gene
    CSRP22  CSRP12  CRIP22  CRIP32  ENSG000002573412  CSRP32  
    Selected SIMAP similar genes for CRIP1 using alignment to 3 protein entries:     CRIP1_HUMAN (see all proteins) (see all similar genes):
    CRIP3    CRIP2    DKFZp686M148    LASP1    ABLIM1    CSRP1
    MICAL3    NRAP    PXN    PDLIM5    DKFZp686P2249    LIMK1
    LIMS3    LIMS1    MICALL2    AAG11    ABLIM2    FHL2

    Find genes that share paralogs with CRIP1           About GenesLikeMe


    4 Pseudogenes.org Pseudogenes for CRIP1
    PGOHUM00000245159 PGOHUM00000246546 PGOHUM00000237942 PGOHUM00000237964


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CRIP1 (see all 58)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1160325051,2
    F--105951289(+) GAGGAC/GAAGGA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs352030321,2
    C,F--105951319(+) TGCCCT/CGGCTA 1 -- us2k15Minor allele frequency- C:0.14NA 128
    rs1861628641,2
    --105951400(+) TATGGA/GCGGAC 1 -- us2k10--------
    rs1907167011,2
    --105951401(+) ATGGGC/TGGACA 1 -- us2k10--------
    rs1165057731,2
    C,F--105951435(+) GCTCGA/C/TGGGGA 1 -- us2k11WA 118
    rs1815276131,2
    C--105951484(+) TCCACA/GGGCAC 1 -- us2k10--------
    rs733620691,2
    C,F--105951537(+) CACCCA/GGAGCA 1 -- us2k13Minor allele frequency- G:0.44WA CSA 121
    rs344480961,2
    C,F,H--105951611(+) CCCCAG/TGGAAA 1 -- us2k12Minor allele frequency- T:0.01NS 280
    rs1115407351,2
    C--105951725(+) TCCCAC/TGATGC 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1171769921,2
    C,F--105951804(+) AGTGGG/CGGTTC 1 -- us2k11Minor allele frequency- C:0.04NA 120

    HapMap Linkage Disequilibrium report for CRIP1 (105952654 - 105955284 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CRIP1 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv2033n71CNV Loss21882294
    dgv2025n71CNV Loss21882294
    nsv902490CNV Loss21882294
    dgv2036n71CNV Loss21882294
    dgv2035n71CNV Loss21882294
    dgv2037n71CNV Loss21882294
    nsv902480CNV Loss21882294
    dgv2032n71CNV Loss21882294
    dgv2020n71CNV Loss21882294
    dgv2024n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CRIP1
    DNA2.0 Custom Variant and Variant Library Synthesis for CRIP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 123875    OMIM disorders: --


    Find genes that share disorders with CRIP1           About GenesLikeMe


    Export disorders for CRIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CRIP1 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with CRIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mapping of the human cysteine-rich intestinal protein gene CRIP1 to the human chromosomal segment 7q11.23. (PubMed id 9480758)1, 3, 9 Garcia-Barcelo M....Waye M.M. (Genomics 1998)
    2. Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells. (PubMed id 9126610)1, 2, 9 Khoo C.... Cousins R.J. (Protein Expr. Purif. 1997)
    3. Isolation and characterization of a cDNA that codes for a LIM- containing protein which is developmentally regulated in heart. (PubMed id 7999070)1, 2, 9 Tsui S.K.W.... Waye M.M.Y. (Biochem. Biophys. Res. Commun. 1994)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate. (PubMed id 9507743)1, 9 DubAc J.Y....Tremblay R.R. (Arch. Androl. 1998)
    6. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients. (PubMed id 22202598)1 Baumhoer D....Nathrath M. (Oncotarget 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 1396 HGNC: 2360 AceView: CRIP1andC14orf80 Ensembl:ENSG00000213145 euGenes: HUgn1396
    ECgene: CRIP1 H-InvDB: CRIP1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CRIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CRIP1 gene:
    Search GeneIP for patents involving CRIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CRIP1  
     OriGene qPCR primer pairs and template standards for CRIP1   OriGene Protein Over-expression Lysate for CRIP1  
     OriGene MassSpec for CRIP1   OriGene clones in human, mouse for CRIP1  
     OriGene qSTAR qPCR primer pairs in human, mouse for CRIP1   OriGene Purified Protein for CRIP1  
     OriGene ORF clones in mouse, rat for CRIP1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CRIP1   OriGene Custom Protein Services for CRIP1  

     
     
     Block miRNA regulation of human, mouse, rat CRIP1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CRIP1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CRIP1 Predesigned siRNA for gene silencing in human, mouse, rat CRIP1
     QuantiFast Probe-based Assays in human, mouse, rat CRIP1 QuantiTect SYBR Green Assays in human, mouse, rat CRIP1
     Custom PCR Arrays for CRIP1 Search Chromatin IP Primers for CRIP1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CRIP1  Search GeneGlobe Interaction Network for CRIP1
     Regulatory tfbs in CRIP1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CRIP1 GenScript cDNA clones with any tag delivered in your preferred vector for CRIP1
     GenScript Custom Assay Services for CRIP1 GenScript Custom overexpressing Cell Line Services for CRIP1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CRIP1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for CRIP1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CRIP1 antibodies
     CRIP1 proteins
     CRIP1 lysates
     Antibodies for CRIP1
     See all of Abcam's Antibodies, Kits and Proteins for CRIP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CRIP1
     Antibodies for CRIP1
     ELISAs for CRIP1
     CLIAs for CRIP1



     Browse ESI BIO Cell Lines and PureStem Progenitors for CRIP1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CRIP1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for CRIP1
     SwitchGear Promoter luciferase reporter plasmids for CRIP1
     ThermoFisher Antibody for CRIP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CRIP1
     Browse compounds at ApexBio
     Search Addgene for plasmids for CRIP1
      Search eBioscience for proteins for CRIP1
      Search eBioscience for elisas for CRIP1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for CRIP1
     antibodies-online antibodies for CRIP1 (11 products)
     antibodies-online kits for CRIP1 (10 products)
     antibodies-online peptides for CRIP1
     antibodies-online proteins for CRIP1 (6 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CRIP1 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4