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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CREBRF Gene

protein-coding   GIFtS: 39
GCID: GC05P172484

CREB3 Regulatory Factor

(Previous name: chromosome 5 open reading frame 41)
(Previous symbol: C5orf41)
  Search for CREBRF
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CREB3 Regulatory Factor1 2     Chromosome 5 Open Reading Frame 411
C5orf411 2 3     Adult Retina Protein2
Luman/CREB3 Recruitment Factor1 2     Luman-Recruiting Factor2
Luman Recruitment Factor2 3     UPF0474 Protein C5orf412
LRF2 3     

External Ids:    HGNC: 240501   Entrez Gene: 1532222   Ensembl: ENSG000001644637   UniProtKB: Q8IUR63   

Export aliases for CREBRF gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CREBRF Gene: 
CREBRF (CREB3 regulatory factor) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: CRERF_HUMAN, Q8IUR6
Function: Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response
(UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_023133.13  NC_018916.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CREBRF
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCREBRF promoter sequence
   Search SABiosciences Chromatin IP Primers for CREBRF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREBRF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.1   Ensembl cytogenetic band:  5q35.1   HGNC cytogenetic band: 5q35.2

CREBRF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CREBRF gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P172484:  view genomic region     (about GC identifiers)

Start:
172,483,355 bp from pter      End:
172,566,291 bp from pter
Size:
82,937 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CRERF_HUMAN, Q8IUR6 (See protein sequence)
Recommended Name: CREB3 regulatory factor  
Size: 639 amino acids; 72149 Da
Subunit: Interacts (via leucine-zipper domain) with CREB3 (via leucine-zipper domain); the interaction promotes
CREB3 degradation
Subcellular location: Nucleus. Note=Colocalizes with CREB3 in nuclear foci
Sequence caution: Sequence=AC008378; Type=Erroneous gene model prediction;
Secondary accessions: B3DFH2 B3KW49 D3DQM2 F5GXN3 Q5HYG4 Q5HYK0 Q86YR3 Q8IZG1
Alternative splicing: 3 isoforms:  Q8IUR6-1   Q8IUR6-2   Q8IUR6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CREBRF: NX_Q8IUR6

Explore proteomics data for CREBRF at MOPED 

Post-translational modifications:

  • UniProtKB: Probably degraded by the proteasome
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IUR6

  • CREBRF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CREBRF Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001161865.1  NP_001161866.1  NP_705835.2  

    ENSEMBL proteins: 
     ENSP00000431107   ENSP00000296953   ENSP00000428290   ENSP00000430801   ENSP00000440075  

    Human Recombinant Protein Products for CREBRF: 
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    Novus Biologicals CREBRF Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA18391022
    GO:0016604nuclear body IDA18391022

    CREBRF for ontologies           About GeneDecksing



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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004827 bZIP

    Graphical View of Domain Structure for InterPro Entry Q8IUR6

    ProtoNet protein and cluster: Q8IUR6

    UniProtKB/Swiss-Prot: CRERF_HUMAN, Q8IUR6
    Similarity: Belongs to the bZIP family. CREBRF subfamily
    Similarity: Contains 1 bZIP (basic-leucine zipper) domain


    CREBRF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CRERF_HUMAN, Q8IUR6
    Function: Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response
    (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci
    Induction: Up-regulated by endoplasmic reticulum stress

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI18391022
    GO:0043565sequence-specific DNA binding IEA--
         
    CREBRF for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CREBRF:
     Increased G2M DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CREBRF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CREBRF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CREBRF 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CREBRF 

    miRNA
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    miRTarBase miRNAs that target CREBRF:
    hsa-mir-155 (MIRT005103)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CREBRF
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CREBRF
    SwitchGear 3'UTR luciferase reporter plasmidCREBRF 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene clones in human, mouse for CREBRF (see all 13)
    OriGene ORF clones in mouse, rat for CREBRF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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    Browse Sino Biological Human cDNA Clones
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                         Customized lentivirus expression plasmids for stable overexpression of CREBRF 

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    Search LifeMap BioReagents cell lines for CREBRF
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREBRF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CREBRF

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CREBRF (Q8IUR61, 3 ENSP000002969534) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD2BP2O954003, ENSP000003049034I2D: score=2 STRING: ENSP00000304903
    CREB3O43889-21, ENSP000003421364EBI-1042699,EBI-625022 STRING: ENSP00000342136
    ZBTB7AENSP000003236704STRING: ENSP00000323670
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA18391022
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006810transport IEA--
    GO:0006986response to unfolded protein IEA--
    GO:0032388positive regulation of intracellular transport IDA18391022

    CREBRF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CREBRF (CRERF)

    Search CenterWatch for drugs/clinical trials and news about CREBRF / CRERF

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CREBRF gene (3 alternative transcripts): 
    NM_001168393.1  NM_001168394.1  NM_153607.2  

    Unigene Cluster for CREBRF:

    CREB3 regulatory factor
    Hs.484195  [show with all ESTs]
    Unigene Representative Sequence: NM_153607
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000522692(uc003mcf.3 uc003mcg.3) ENST00000296953(uc011dfd.1)
    ENST00000520420 ENST00000520464 ENST00000517882 ENST00000523161 ENST00000540014(uc003mch.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CREBRF
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CREBRF
    SwitchGear 3'UTR luciferase reporter plasmidCREBRF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CREBRF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CREBRF
    Clone
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    OriGene clones in human, mouse for CREBRF (see all 13)
    OriGene ORF clones in mouse, rat for CREBRF
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    GenScript Custom all cDNA clones Services for CREBRF
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CREBRF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREBRF
    Sirion Biotech Customized lentivirus for stable overexpression of CREBRF 
                         Customized lentivirus expression plasmids for stable overexpression of CREBRF 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CREBRF
    OriGene qSTAR qPCR primer pairs in human, mouse for CREBRF
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CREBRF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CREBRF

    Additional mRNA sequence: 

    AK122675.1 AK124117.1 AK291677.1 AK297424.1 AK300043.1 AY139008.1 AY174896.1 AY635785.1 
    BC041709.1 BC043185.2 BX647768.1 

    9 DOTS entries:

    DT.91991182  DT.92052308  DT.451573  DT.95210676  DT.120813712  DT.65288542  DT.95272153  DT.405613 
    DT.92027438 

    24/169 AceView cDNA sequences (see all 169):

    BX647768 BG150109 AW768436 AI808566 CA393950 CA413726 AI436055 BE465448 
    BX118518 BM723244 AW342063 AA481626 BU675873 BQ027319 NM_153607 N50563 
    AA290875 AA442286 BU736313 BQ025672 CA395235 AA437223 AI276414 BF593533 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CREBRF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTTCTCAT
    CREBRF Expression
    About this image


    See CREBRF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CREBRF

    SOURCE GeneReport for Unigene cluster: Hs.484195
        SABiosciences Custom PCR Arrays for CREBRF
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREBRF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CREBRF gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Crebrf1 , 5 RIKEN cDNA A930001N09 gene5
    CREB3 regulatory factor1
    89.88(n)1
    93.9(a)1
      17 (13.50 cM)5
    771281  NM_029870.21  NP_084146.11 
     267156505 
    chicken
    (Gallus gallus)
    Aves C13H5orf411 chromosome 13 open reading frame, human C5orf41 82.2(n)
    89.06(a)
      416206  XM_001231573.2  XP_001231574.1 
    lizard
    (Anolis carolinensis)
    Reptilia CREBRF6
    Uncharacterized protein
    82(a)
    1 ↔ 1
    2(124536117-124554236)
    zebrafish
    (Danio rerio)
    Actinopterygii crebrf1 creb3 regulatory factor 63.3(n)
    62.93(a)
      100149876  XM_001920091.3  XP_001920126.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG136246
    --
    16(a)
    1 ↔ 1
    3R(20383090-20408586)


    ENSEMBL Gene Tree for CREBRF (if available)
    TreeFam Gene Tree for CREBRF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1488 SNPs in CREBRF are shown (see all 1488)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs297771,2
    C,F,A,H--172481414(-) GCAGCC/GAGGTT 3 -- us2k110Minor allele frequency- G:0.31NA CSA WA EA 371
    rs1479013771,2
    --172481461(+) AACGTA/GCCCGT 3 -- us2k10--------
    rs777860121,2
    F--172481560(+) TATGCC/TGGGGA 3 -- us2k11Minor allele frequency- T:0.03EA 120
    rs1884721811,2
    --172481597(+) CGAGTA/C/TGGGGT 3 -- us2k10--------
    rs1416843231,2
    --172481750(+) CCTTCA/TTTGGG 3 -- us2k10--------
    rs784628581,2
    C,F--172481753(+) TCATTG/AGGCAT 3 -- us2k12Minor allele frequency- A:0.04CSA WA 120
    rs1917078691,2
    --172481796(+) GCTACA/GGAGGA 3 -- us2k10--------
    rs297761,2
    C,F,A,H--172481818(-) GGAAAC/GTAAAA 3 -- us2k131Minor allele frequency- G:0.37NS EA NA CSA WA 3185
    rs1843009921,2
    --172482106(+) GTTAAA/TTTGTG 3 -- us2k10--------
    rs2019052391,2
    --172482379(+) TTATT-/CCCCCGT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for CREBRF (172483355 - 172566291 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CREBRF: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CREBRF
    DNA2.0 Custom Variant and Variant Library Synthesis for CREBRF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CREBRF gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CREBRF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response. (PubMed id 18391022)1, 2, 3 Audas T.E.... Lu R. (2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Luman/CREB3 recruitment factor regulates glucocorticoi d receptor activity and is essential for prolactin-mediated maternal instinct. (PubMed id 23071095)1 Martyn A.C....Lu R. (2012)
    4. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    6. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 153222 HGNC: 24050 AceView: LOC153222 Ensembl:ENSG00000164463 euGenes: HUgn153222
    ECgene: CREBRF H-InvDB: CREBRF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CREBRF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CREBRF gene:
    Search GeneIP for patents involving CREBRF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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