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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CREB5 Gene

protein-coding   GIFtS: 55
GCID: GC07P028305

CAMP Responsive Element Binding Protein 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CAMP Responsive Element Binding Protein 51 2     CAMP Response Element-Binding Protein CRE-BPa2
CAMP Response Element Binding Protein CRE-Bpa1 2     CAMP Responsive Element Binding Protein 5 Isoform Alpha2
CREB-52 3     Cyclic AMP-Responsive Element-Binding Protein 52
CAMP-Responsive Element-Binding Protein 52 3     CRE-BPa3
CRE-BPA2     CREBPA3
H_GS165L15.12     

External Ids:    HGNC: 168441   Entrez Gene: 95862   Ensembl: ENSG000001465927   UniProtKB: Q029303   

Export aliases for CREB5 gene to outside databases

Previous GC identifers: GC07P028047 GC07P028194 GC07P028081 GC07P028112


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CREB5 Gene:
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family
contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or
a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced
transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for CREB5 Gene: 
CREB5 (cAMP responsive element binding protein 5) is a protein-coding gene. Diseases associated with CREB5 include ascariasis, and trichuriasis, and among its related super-pathways are Amphetamine addiction and Circadian entrainment. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ENSG00000267281.

UniProtKB/Swiss-Prot: CREB5_HUMAN, Q02930
Function: Binds to the cAMP response element and activates transcription

Gene Wiki entry for CREB5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CREB5 gene promoter:
         E2F-4   E2F-3a   E2F-5   RP58   E2F-2   IRF-2   POU2F1   E2F   E2F-1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): CREB5 promoter sequence
   Search SABiosciences Chromatin IP Primers for CREB5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREB5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.1   Ensembl cytogenetic band:  7p15.1   HGNC cytogenetic band: 7p15

CREB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CREB5 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P028305:  view genomic region     (about GC identifiers)

Start:
28,338,940 bp from pter      End:
28,865,511 bp from pter
Size:
526,572 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 28,389,121-28,915,762     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CREB5_HUMAN, Q02930 (See protein sequence)
Recommended Name: Cyclic AMP-responsive element-binding protein 5  
Size: 508 amino acids; 56918 Da
Subunit: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1
Subcellular location: Nucleus (Probable)
Secondary accessions: A8KA51 B4DU13 B5BUH3 C9JK47 Q05886 Q06246 Q75N02 Q86UJ9
Alternative splicing: 4 isoforms:  Q02930-1   Q02930-2   Q02930-3   Q02930-4   

Explore the universe of human proteins at neXtProt for CREB5: NX_Q02930

Explore proteomics data for CREB5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q02930

  • CREB5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CREB5 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001011666.1  NP_004895.2  NP_878901.2  NP_878902.2  

    ENSEMBL proteins: 
     ENSP00000379593   ENSP00000394088   ENSP00000350359   ENSP00000379594   ENSP00000387197  
     ENSP00000394979   ENSP00000379592   ENSP00000440429  

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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CREB5 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC8378084

    CREB5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    bZIP: basic leucine zipper proteins

    5 InterPro protein domains:
     IPR004827 bZIP
     IPR015880 Znf_C2H2-like
     IPR016378 TF_cAMP-dep
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q02930

    ProtoNet protein and cluster: Q02930

    1 Blocks protein domain: IPB011616 bZIP transcription factor

    UniProtKB/Swiss-Prot: CREB5_HUMAN, Q02930
    Similarity: Belongs to the bZIP family
    Similarity: Contains 1 bZIP (basic-leucine zipper) domain
    Similarity: Contains 1 C2H2-type zinc finger


    CREB5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CREB5_HUMAN, Q02930
    Function: Binds to the cAMP response element and activates transcription

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
    GO:0003676nucleic acid binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IDA8378084
    GO:0005515protein binding IPI8440710
    GO:0008270zinc ion binding ----
         
    CREB5 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for CREB5:
     G0/1 arrest  Increased G1 DNA content  Increased cell size 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Creb5):
     adipose tissue  behavior/neurological  cellular  growth/size  homeostasis/metabolism 
     integument  mortality/aging 

    CREB5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Creb5tm1Sis for CREB5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CREB5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CREB5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CREB5 
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    miRNA
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    8/198 QIAGEN miScript miRNA Assays for microRNAs that regulate CREB5 (see all 198):
    hsa-miR-124* hsa-miR-520f hsa-miR-361-5p hsa-miR-106a hsa-miR-938 hsa-miR-519a hsa-miR-149 hsa-miR-376a*
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CREB5 About   (see all 12)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Amphetamine addiction
    Amphetamine addiction0.44
    Cocaine addiction0.44
    2Circadian entrainment
    Dopaminergic synapse0.37
    Cholinergic synapse0.37
    3Insulin secretion
    Insulin secretion0.36
    Thyroid hormone synthesis0.36
    4Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Huntington's disease0.47
    5Glioma
    Prostate cancer0.39

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/15         Kegg Pathways  (Kegg details for CREB5) (see all 15):
        PI3K-Akt signaling pathway
    TNF signaling pathway
    Cholinergic synapse
    Dopaminergic synapse
    Insulin secretion


    CREB5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CREB5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/19 Interacting proteins for CREB5 (Q029303 ENSP000003503594) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    JUNP054123, ENSP000003602664I2D: score=2 STRING: ENSP00000360266
    ATF2P153363, ENSP000002641104I2D: score=1 STRING: ENSP00000264110
    KRTAP5-9P263713I2D: score=1 
    LGALS13Q9UHV83I2D: score=1 
    CREBBPENSP000002623674STRING: ENSP00000262367
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006366transcription from RNA polymerase II promoter TAS8378084
    GO:0045444fat cell differentiation IEA--
    GO:0045893positive regulation of transcription, DNA-dependent IDA8378084
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ----

    CREB5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CREB5

    1 HMDB Compound for CREB5    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cyclic AMPCyclic AMP (see all 19)60-92-4--

    Search CenterWatch for drugs/clinical trials and news about CREB5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CREB5 gene (4 alternative transcripts): 
    NM_001011666.1  NM_004904.2  NM_182898.2  NM_182899.3  

    Unigene Cluster for CREB5:

    CAMP responsive element binding protein 5
    Hs.437075  [show with all ESTs]
    Unigene Representative Sequence: NM_182898
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396299 ENST00000469531 ENST00000478078 ENST00000482692(uc003szp.3)
    ENST00000424599 ENST00000357727(uc003szo.3 uc003szq.3 uc003szr.3 uc003szs.3)
    ENST00000396300 ENST00000409603 ENST00000461921 ENST00000426500 ENST00000396298
    ENST00000468391(uc011jzr.2) ENST00000484383 ENST00000468813 ENST00000498316

    miRNA
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    8/198 QIAGEN miScript miRNA Assays for microRNAs that regulate CREB5 (see all 198):
    hsa-miR-124* hsa-miR-520f hsa-miR-361-5p hsa-miR-106a hsa-miR-938 hsa-miR-519a hsa-miR-149 hsa-miR-376a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    Additional mRNA sequence: 

    AB209262.1 AB451409.1 AK021493.1 AK057151.1 AK292916.1 AK298121.1 AK300455.1 AK316187.1 
    BC059400.1 L05515.1 L05911.1 L05912.1 L05913.1 

    12 DOTS entries:

    DT.91750301  DT.100812990  DT.95374150  DT.100812991  DT.97828917  DT.87014787  DT.95209779  DT.97825503 
    DT.100747131  DT.121057538  DT.95225955  DT.438809 

    24/78 AceView cDNA sequences (see all 78):

    AA582287 AA700776 AV754746 BX279704 AL706571 BM468660 BP345509 CK820213 
    AL706583 BC059400 AA581655 CB149302 AU117379 L05911 AU139456 BE620362 
    AA748577 BI517600 BG546617 AW024551 BX107718 AI743249 L05515 AI609531 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CREB5 expression in normal human tissues (normalized intensities)      CREB5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CREB5 Expression
    About this image


    CREB5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Mesenchymal Condensate Cells Zeugopod
             Normal Human Articular chondrocytes (NHAC)   
     
     Uncategorized (Uncategorized)    fully expand to see all 2 entries
             PureStem Progenitor ES-263
     
     Bone (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Limb (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Hair
             hair follicle sub-bulge   

    See CREB5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CREB5

    SOURCE GeneReport for Unigene cluster: Hs.437075
        SABiosciences Custom PCR Arrays for CREB5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CREB5 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Creb55 cAMP responsive element binding protein 5   --   6 (25.90 cM) 53573374 
    chicken
    (Gallus gallus)
    Aves CREB51 cAMP responsive element binding protein 5 86.06(n)
    94.67(a)
      428435  XM_425995.3  XP_425995.2 
    lizard
    (Anolis carolinensis)
    Reptilia CREB56
    cAMP responsive element binding protein 5
    93(a)
    1 ↔ 1
    GL343275.1(364116-703330)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5659101 cyclic AMP-responsive element-binding protein 5-like 72.18(n)
    79.13(a)
      565910  XM_001921055.1  XP_001921090.1 


    ENSEMBL Gene Tree for CREB5 (if available)
    TreeFam Gene Tree for CREB5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CREB5 gene
    ENSG000002672812  ATF72  ATF22  
    2 SIMAP similar genes for CREB5 using alignment to 5 protein entries:     CREB5_HUMAN (see all proteins):
    ATF2    ATF7

    CREB5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/11054 SNPs in CREB5 are shown (see all 11054)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1506803761,2
    C,Funtested128758481(+) TCTTCC/TGCCGT 8 S syn11Minor allele frequency- T:0.00NA 4552
    rs788405531,2
    C--28275323(+) gcctg-/GGGAA 
            
    caaag
    1 -- int10--------
    rs1135528611,2
    C,F--28336976(+) ACAGAC/GAGTAA 1 -- us2k12Minor allele frequency- G:0.03NA 122
    rs1426347451,2
    --28336979(+) GACAGG/TAAGTG 1 -- us2k10--------
    rs1871351851,2
    --28336983(+) GTAAGG/TGGTAG 1 -- us2k10--------
    rs1923593641,2
    --28337040(+) TCCCAC/TTGTGT 1 -- us2k10--------
    rs1833206691,2
    --28337410(+) ATCAAC/TGCTTG 1 -- us2k10--------
    rs1870024291,2
    --28337756(+) TAAACA/GAGTGC 1 -- us2k10--------
    rs1502814031,2
    --28337760(+) CGAGTA/GCCATG 1 -- us2k10--------
    rs1458046591,2
    --28337804(+) GTATTA/CAGCCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CREB5 (28338940 - 28588940 bp, first 250kb of CREB5)

    Structural Variations
         Database of Genomic Variants (DGV) 10/22 variations for CREB5 (see all 22):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2662053CNV Deletion23128226
    esv2470943CNV Deletion19546169
    esv2141048CNV Deletion18987734
    esv3333CNV Deletion18987735
    esv2659069CNV Deletion23128226
    dgv1189e199CNV Deletion23128226
    esv2734175CNV Deletion23290073
    esv2734176CNV Deletion23290073
    nsv821171CNV Deletion20802225
    esv2676680CNV Deletion23128226

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    6 diseases for CREB5:    About MalaCards
    ascariasis    trichuriasis    encephalitis    huntington's disease
    prostate cancer    prostatitis


    CREB5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CREB5
    Human Genome Epidemiology (HuGE) Navigator: CREB5 (5 documents)

    Export disorders for CREB5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CREB5 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with CREB5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Regulation of trans-activating capacity of CRE-BPa by phorbol ester tumor promoter TPA. (PubMed id 8378084)1, 2, 3, 9 Zu Y.-L.... Ishii S. (1993)
    2. Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1. (PubMed id 8440710)1, 2, 3, 9 Nomura N....Ishii S. (1993)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Inherited genetic variant predisposes to aggressive b ut not indolent prostate cancer. (PubMed id 20080650)1, 4 Xu J....Isaacs W.B. (2010)
    5. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
    6. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PubMed id 18839057)1, 4 Lesch K.P....Jacob C. (2008)
    7. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9586 HGNC: 16844 AceView: CREB5 Ensembl:ENSG00000146592 euGenes: HUgn9586
    ECgene: CREB5 Kegg: 9586 H-InvDB: CREB5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CREB5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CREB5 gene:
    Search GeneIP for patents involving CREB5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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