CREB3L4 Gene
protein-coding GIFtS: 53
GCID: GC01P153940
|
|
cAMP responsive element binding protein 3-like 4
| |
Aliases
for CREB3L4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CAMP Responsive Element Binding Protein 3-Like 41 2 | | Transcript Induced In Spermiogenesis Protein 402 3 | | CREB41 2 3 5 | | CREB-42 3 | | ATCE11 2 3 | | JAL2 3 | | HJAL1 | | CAMP-Responsive Element-Binding Protein 3-Like Protein 42 3 | | AIBZIP2 3 5 | | CAMP-Responsive Element-Binding Protein 42 3 | | CREB31 2 | | CAMP Responsive Element Binding Protein 12 | | AIbZIP1 3 | | Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 42 | | Androgen-Induced Basic Leucine Zipper Protein2 3 | | Tisp403 | | Attaching To CRE-Like 12 3 | | Tisp403 | | Cyclic AMP-Responsive Element-Binding Protein 42 3 | | |
Export aliases for CREB3L4 gene to outside databasesPrevious GC identifers: GC01P151157 GC01P150753 GC01P152207 GC01P125302 |
Summaries
for CREB3L4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CREB3L4:
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it tothe ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and thisprotein may function in a number of processing pathways including protein processing. Multiple transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, Dec 2011)
UniProtKB/Swiss-Prot: CR3L4_HUMAN, Q8TEY5Function: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element(UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and hastranscriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activityfrom NF-kappa-B-containing regulatory elements (By similarity)
|
Genomic Views
for CREB3L4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CREB3L4 gene promoter:
STAT5A Tal-1beta CREB PPAR-gamma1 USF-1 deltaCREB PPAR-gamma2 ITF-2 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for CREB3L4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREB3L4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.2CREB3L4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P153940: view genomic region
(about GC identifiers)
Start:
|
153,940,010 bp from pter |
End:
|
153,946,839 bp from pter |
Size:
|
6,830 bases |
Orientation:
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plus strand |
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Proteins
for CREB3L4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CR3L4_HUMAN, Q8TEY5 (See
protein sequence)Recommended Name: Cyclic AMP-responsive element-binding protein 3-like protein 4 Size: 395 amino acids; 43432 Da
Subunit: Binds DNA as a dimer (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane;Single-pass type II membrane protein (Potential). Note=May also be located in Golgi apparatus
Subcellular location: Processed cyclic AMP-responsive element-binding protein 3-like protein 4: Nucleus. Note=Under ERstress the cleaved N-terminal cytoplasmic domain translocates into the nucleus (By similarity)
Secondary accessions: D3DV62 Q5T4L0 Q86YW6Alternative splicing: 2 isoforms: Q8TEY5-1 Q8TEY5-2 Explore the universe of human proteins at neXtProt for CREB3L4: NX_Q8TEY5
Post-translational modifications:
N-glycosylated in the C-terminal region1
Controlled by regulated intramembrane proteolysis (RIP). Following ER stress a fragment containing the cytoplasmictranscription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site-1 andsite-2 proteases (PS1 and PS2). PS1 cleavage may be suppressed by a determinant in the C-terminal region (Bysimilarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TEY5
CREB3L4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001242907.1 NP_001242908.1 NP_001242909.1 NP_001242910.1 NP_570968.1
ENSEMBL proteins: ENSP00000391847 ENSP00000357596 ENSP00000271889 ENSP00000357590 ENSP00000357592 ENSP00000357589 ENSP00000402308 ENSP00000385104
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
CREB3L4 for ontologies About GeneDecksing
CREB3L4 Antibody Products:
Assay Products for CREB3L4: |
Protein
Domains /
Families
for CREB3L4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CREB3L4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TEY5ProtoNet protein and cluster: Q8TEY5 1 Blocks protein family: IPB011616 bZIP transcription factor
UniProtKB/Swiss-Prot: CR3L4_HUMAN, Q8TEY5Similarity: Belongs to the bZIP family. ATF subfamilySimilarity: Contains 1 bZIP (basic-leucine zipper) domain |
Function
for CREB3L4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CR3L4_HUMAN, Q8TEY5Function: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element(UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and hastranscriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activityfrom NF-kappa-B-containing regulatory elements (By similarity)Induction: By androgens
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CREB3L4 (NM_130898) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CREB3L4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREB3L4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L4 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
-- | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0043565 | sequence-specific DNA binding |
IEA | -- | | GO:0046983 | protein dimerization activity |
-- | -- |
CREB3L4 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CREB3L4:
Animal Models:
Mouse knock-out Creb3l4tm1Noj for CREB3L4
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Creb3l4):
CREB3L4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CREB3L4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/32 super-pathways (see all 32) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of cAMP-Dependent PKA | | | 2 | CREB Pathway | | | 3 | GPCR Pathway | | | 4 | Rho Family GTPases | | | 5 | G-Beta Gamma Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/45 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CREB3L4 (see all 45)
1  BioSystems Pathway for CREB3L4
5 
Kegg Pathways (Kegg details for CREB3L4):
CREB3L4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CREB3L4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/31 Interacting proteins for CREB3L4 (Q8TEY53 ENSP000002718894) via UniProtKB, MINT, STRING, and/or I2D (see all 31)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006986 | response to unfolded protein |
IEA | -- | | GO:0007283 | spermatogenesis |
IEA | -- | | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter |
IEA | -- |
CREB3L4 for ontologies About GeneDecksing
|
Drugs & Compounds
for CREB3L4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CREB3L4
Search CenterWatch for drugs/clinical trials and news about CREB3L4 / CR3L4
|
Transcripts
for CREB3L4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CREB3L4 gene (5 alternative transcripts): NM_001255978.1 NM_001255979.1 NM_001255980.1 NM_001255981.1 NM_130898.3 Unigene Cluster for CREB3L4: CAMP responsive element binding protein 3-like 4 Hs.744219 [show with all ESTs]Unigene Representative Sequence: NM_13089814 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000477617 ENST00000449724 ENST00000368607(uc001fdn.3 uc001fdo.3)
ENST00000271889(uc001fdm.1) ENST00000461688 ENST00000368601 ENST00000368603(uc001fdr.2 uc001fdq.2)
ENST00000368600 ENST00000479010 ENST00000492729(uc010peg.1) ENST00000473340
ENST00000431292 ENST00000468845 ENST00000405694(uc010pef.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CREB3L4 (NM_130898) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CREB3L4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREB3L4 |
Additional cDNA sequence: AB052778.1 AF394167.1 AF468007.1 AK297703.1 AK304259.1 AK304665.1 AY049977.1 BC038962.1 BX647716.1 NR_045658.1 17 DOTS entries: DT.421099 DT.97844583 DT.97844584 DT.75133749 DT.100776366 DT.100776368 DT.121436532 DT.95277031 DT.121436443 DT.95098506 DT.102825513 DT.121436551 DT.100670043 DT.100776364 DT.121436403 DT.95149731 DT.121436428 24/165 AceView cDNA sequences (see all 165): AA587806 NM_130898 BQ224313 BM846663 AI028440 AB052778 CD722502 CB068529 CB068592 AI151181 CA487547 CK429797 CR592077 AI493479 BI768195 AL528505 BM977529 AY049977 AI872174 CR624438 AL528908 BM846254 CR624400 AI130985
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CREB3L4 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CREB3L4
|
Expression
for CREB3L4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CREB3L4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGATGAGAT
About this image
See CREB3L4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CREB3L4
SOURCE GeneReport for Unigene cluster: Hs.744219
UniProtKB/Swiss-Prot: CR3L4_HUMAN, Q8TEY5Tissue specificity: According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast andprostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression issignificantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According toPubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine,testis, leukocyte and thymus
SABiosciences Custom PCR Arrays for CREB3L4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CREB3L4
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L4 |
Orthologs
for CREB3L4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CREB3L4 gene from 3/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb26f102 |
Transcribed sequence with weak similarity to protein more |
75.43(n) |
|
57039665 |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
16(a) |
1 → many |
Group14.4(543638-551371) |
worm
(Caenorhabditis elegans) |
Secernentea |
crh-26let-6076 |
LEThal family member (let-607) |
18(a)10(a) |
possible ortholog1 ↔ many |
II(5179028-5187561) I(6574003-6585176) |
ENSEMBL Gene Tree for CREB3L4 (if available)
TreeFam Gene Tree for CREB3L4 (if available) |
Paralogs
for CREB3L4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CREB3L4 gene
- CREB3L22 CREB32 CREB3L12 CREB3L32
2 SIMAP similar genes for CREB3L4 using alignment to 5 protein entries: CR3L4_HUMAN (see all proteins):CREM CREB3L3
CREB3L4 for paralogs About GeneDecksing
|
Genomic Variants
for CREB3L4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CREB3L4 (153940010 - 153946839 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CREB3L4: --
Human Gene Mutation Database (HGMD): CREB3L4
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CREB3L4 |
|
Disorders
/ Diseases
for CREB3L4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CREB3L4 for disorders About GeneDecksing
OMIM gene information: 607138
OMIM disorders: --
7  diseases for CREB3L4: About MalaCardshuntington's disease hepatocellular carcinoma prostate disease prostatitis
prostate cancer sarcoma carcinoma
Export disorders for CREB3L4 gene to outside databases
|
Publications
for CREB3L4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CREB3L4 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with CREB3L4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up- regulated by androgens in LNCaP human prostate cancer cells. (PubMed id 11830526)1, 2, 9 Qi H.... Labrie C. (2002)
- CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. (PubMed id 16236796)1, 2 Stirling J. and O'hare P. (2006)
- Molecular cloning and characterization of a novel human cAMP response element-binding (CREB) gene (CREB4). (PubMed id 12111373)1, 2 Cao G.... Mao Y. (2002)
- Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells. (PubMed id 17712038)1, 9 Ben Aicha S....Labrie C. (2007)
- Genome-wide association identifies genetic variants as sociated with lentiform nucleus volume in N = 1345 young and elderly subjects. (PubMed id 22903471)1 Hibar D.P....Thompson P.M. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma. (PubMed id 18068530)1 Inagaki Y....Okanoue T. (2008)
- Androgen-regulated transcription factor AIbZIP in prostate cancer. (PubMed id 17933519)1 Labrie C....Calvo E. (2008)
- Evaluation of AIbZIP and Cdc47 as markers for human prostatic diseases. (PubMed id 17270658)2 Levesque M.H.... Labrie C. (2007)
|
External Searches for CREB3L4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CREB3L4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CREB3L4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CREB3L4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CREB3L4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CREB3L4 gene:
Search GeneIP for patents involving CREB3L4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CREB3L4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for CREB3L4 | | OriGene shRNA RFP for CREB3L4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CREB3L4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CREB3L4 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CREB3L4 | | OriGene 3'-UTR Clone for CREB3L4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CREB3L4 | | OriGene Custom Protein Services for CREB3L4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CREB3L4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CREB3L4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREB3L4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CREB3L4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CREB3L4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CREB3L4 |
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| | | | Search Tocris compounds for CREB3L4 |
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 | | | CREB3L4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L4 |
|  |  |  | | | | ThermoFisher Antibodies for CREB3L4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREB3L4 |
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