CREB3L2 Gene
protein-coding GIFtS: 59
GCID: GC07M137559
|
|
cAMP responsive element binding protein 3-like 2
| |
Aliases
for CREB3L2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CAMP Responsive Element Binding Protein 3-Like 21 2 | | B-ZIB Transcription Factor2 | | BBF2H71 2 3 | | Basic Transcription Factor 22 | | TCAG_19514391 2 | | Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 22 | | BBF2 Human Homolog On Chromosome 72 3 | | FUS/BBF2H7 Protein2 | | CAMP-Responsive Element-Binding Protein 3-Like Protein 22 3 | | |
Export aliases for CREB3L2 gene to outside databasesPrevious GC identifers: GC07M136981 GC07M136975 GC07M137021 GC07M137210 GC07M131867 |
Summaries
for CREB3L2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CREB3L2:
This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but formhomodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Dec 2011)
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1Function: Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase.Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription ofunfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Alsoregulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a keyrole in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity)
|
Genomic Views
for CREB3L2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CREB3L2 gene promoter:
AML1a p300 Tal-1beta E47 c-Rel CP2 LyF-1 Pax-4a ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for CREB3L2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREB3L2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q33 HGNC cytogenetic band: 7q34CREB3L2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M137559: view genomic region
(about GC identifiers)
Start:
|
137,559,725 bp from pter |
End:
|
137,686,846 bp from pter |
Size:
|
127,122 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 136,905,109-137,032,068 |
|
Proteins
for CREB3L2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1 (See
protein sequence)Recommended Name: Cyclic AMP-responsive element-binding protein 3-like protein 2 Size: 520 amino acids; 57415 Da
Subunit: Binds DNA as a dimer (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein
Subcellular location: Processed cyclic AMP-responsive element-binding protein 3-like protein 2: Nucleus. Note=Under ERstress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
Secondary accessions: Q6P454 Q6ZMR6Alternative splicing: 3 isoforms: Q70SY1-1 Q70SY1-2 Q70SY1-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CREB3L2: NX_Q70SY1
Post-translational modifications:
Controlled by regulated intramembrane proteolysis (RIP). Following ER stress a fragment containing the cytoplasmictranscription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site-1 andsite-2 proteases (PS1 and PS2)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q70SY1
CREB3L2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001240704.1 NP_919047.2
ENSEMBL proteins: ENSP00000329140 ENSP00000403550 ENSP00000410314 ENSP00000388917 ENSP00000402889
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CREB3L2 for ontologies About GeneDecksing
CREB3L2 Antibody Products:
Assay Products for CREB3L2: |
Protein
Domains /
Families
for CREB3L2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CREB3L2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q70SY1ProtoNet protein and cluster: Q70SY1 1 Blocks protein family: IPB011616 bZIP transcription factor
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1Similarity: Belongs to the bZIP family. ATF subfamilySimilarity: Contains 1 bZIP (basic-leucine zipper) domain |
Function
for CREB3L2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1Function: Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase.Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription ofunfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Alsoregulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a keyrole in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity)
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CREB3L2 (NM_194071) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
CREB3L2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CREB3L2:
Animal Models:
Mouse knock-out Creb3l2tm1Kami for CREB3L2
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Creb3l2):
CREB3L2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CREB3L2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Vasopressin-regulated water reabsorption | | | 2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 3 | Glioma | | | 4 | Basal cell carcinoma | | | 5 | Development Angiotensin activation of ERK | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Kegg Pathways (Kegg details for CREB3L2):
CREB3L2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CREB3L2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/22 Interacting proteins for CREB3L2 (Q70SY13 ENSP000003291404) via UniProtKB, MINT, STRING, and/or I2D (see all 22)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
CREB3L2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CREB3L2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CREB3L2
1 HMDB Compound for CREB3L2 About this table
Search CenterWatch for drugs/clinical trials and news about CREB3L2 / CR3L2
|
Transcripts
for CREB3L2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CREB3L2 gene (2 alternative transcripts): NM_001253775.1 NM_194071.3 Unigene Cluster for CREB3L2: CAMP responsive element binding protein 3-like 2 Hs.490273 [show with all ESTs]Unigene Representative Sequence: NM_1940716 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000330387(uc003vtv.3 uc003vtw.3) ENST00000456390(uc003vtx.2)
ENST00000452463(uc003vty.4) ENST00000458726 ENST00000420629 ENST00000468127
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CREB3L2 (NM_194071) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CREB3L2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREB3L2 |
Additional cDNA sequence: AJ549092.1 AJ549387.1 AK293048.1 AL080209.1 BC046181.1 BC063666.1 BC110813.1 BC131723.1 BX648300.1 BX649143.1 CR749563.1 20 DOTS entries: DT.91933479 DT.100696668 DT.101965632 DT.204213 DT.100790846 DT.100746865 DT.92053939 DT.91898223 DT.405778 DT.70105155 DT.100790845 DT.40287540 DT.407629 DT.95160810 DT.100790844 DT.121058745 DT.40206132 DT.95140218 DT.100790843 DT.91820768 24/134 AceView cDNA sequences (see all 134): CA422461 AI262707 CR749563 BU194910 AI032468 AI341211 BG236289 AI651873 AA861496 AI962466 CK429764 BU553910 CD557473 AA374818 AA005122 BG012564 AW453050 AA115304 AK131517 AI638783 BX092349 BQ438006 CA391461 AA704896
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CREB3L2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CREB3L2
|
Expression
for CREB3L2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CREB3L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTTACACTA
About this image
See CREB3L2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CREB3L2
SOURCE GeneReport for Unigene cluster: Hs.490273
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1Tissue specificity: Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels inheart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected inbrain and heart
SABiosciences Custom PCR Arrays for CREB3L2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CREB3L2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CREB3L2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CREB3L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CREB3L2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L2 |
Orthologs
for CREB3L2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CREB3L2 gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CREB3L21 |
cAMP responsive element binding protein 3-like 2 |
70.8(n)
68.02(a) |
|
418123 XM_416356.3 XP_416356.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CREB3L26 |
-- |
64(a) |
1 ↔ 1 |
5(16272168-16302753) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BU908500.12 |
-- |
75.28(n) |
|
BU908500.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
creb3l21 |
cAMP responsive element binding protein 3-like 2 |
60.31(n)
56.43(a) |
|
791169 NM_001080651.1 NP_001074120.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CrebA6 |
Cyclic-AMP response element binding protein A |
23(a) |
1 → many |
3L(15528514-15546314) |
ENSEMBL Gene Tree for CREB3L2 (if available)
TreeFam Gene Tree for CREB3L2 (if available) |
Paralogs
for CREB3L2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CREB3L2 gene
- CREB32 CREB3L42 CREB3L12 CREB3L32
2 SIMAP similar genes for CREB3L2 using alignment to 5 protein entries: CR3L2_HUMAN (see all proteins):DKFZp686N2325 CREB3L1
CREB3L2 for paralogs About GeneDecksing
|
Genomic Variants
for CREB3L2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CREB3L2 (137559725 - 137686846 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CREB3L2
2 CNVs: 100139 7605
1 Indel: 64959 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CREB3L2 |
|
Disorders
/ Diseases
for CREB3L2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CREB3L2 for disorders About GeneDecksing
OMIM gene information: 608834
OMIM disorders: --
UniProtKB/Swiss-Prot: CR3L2_HUMAN, Q70SY1
Note=A chromosomal aberration involving CREB3L2 is found in low grade fibromyxoid sarcoma (LGFMS).Translocation t(7;16)(q33;p11) with FUS
11  diseases for CREB3L2: About MalaCardsossifying fibromyxoid tumor sarcoma ring chromosomes myxoid liposarcoma
liposarcoma huntington's disease fibrosarcoma prostate cancer
prostatitis thyroiditis neuronitis
4 diseases from the University of Copenhagen DISEASES database for CREB3L2:Sarcoma Myxoid liposarcoma Fibrosarcoma Extraskeletal myxoid chondrosarcoma 1 Novoseek disease relationship for CREB3L2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sarcoma |
57.4 |
4 |
17117415 (2), 12915480 (2) |
Human Genome Epidemiology (HuGE) Navigator: CREB3L2 (2 documents)
Export disorders for CREB3L2 gene to outside databases
|
Publications
for CREB3L2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CREB3L2 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with CREB3L2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. (PubMed id 17178827)1, 2, 9 Kondo S.... Imaizumi K. (2007)
- Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma. (PubMed id 12915480)1, 2, 9 Storlazzi C.T.... Panagopoulos I. (2003)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera. (PubMed id 17117415)1, 9 Panagopoulos I....Mertens F. (2007)
- The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma. (PubMed id 15139001)2, 9 Panagopoulos I.... Mertens F. (2004)
- BBF2H7-mediated Sec23A pathway is required for endopla smic reticulum-to-Golgi trafficking in dermal fibroblasts to promote collagen sy nthesis. (PubMed id 22495181)1 Ishikura-Kinoshita S....Tsuji-Naito K. (2012)
- FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1. (PubMed id 21536545)1 MAPller E....Mertens F. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
|
External Searches for CREB3L2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CREB3L2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CREB3L2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CREB3L2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CREB3L2 gene:
Search GeneIP for patents involving CREB3L2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CREB3L2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CREB3L2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CREB3L2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CREB3L2 | | | OriGene Protein Over-expression Lysate for CREB3L2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CREB3L2 | | OriGene 3'-UTR Clone for CREB3L2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CREB3L2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CREB3L2 | | OriGene Custom Protein Services for CREB3L2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CREB3L2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CREB3L2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CREB3L2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CREB3L2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CREB3L2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CREB3L2 |
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| | | | Search Tocris compounds for CREB3L2 |
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 | | | CREB3L2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CREB3L2 |
|  |  |  | | | | ThermoFisher Antibodies for CREB3L2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CREB3L2 |
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