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Aliases for CRCT1 Gene

Aliases for CRCT1 Gene

  • Cysteine-Rich C-Terminal 1 2 3
  • Protein NICE-1 3 4
  • C1orf42 3 4
  • Chromosome 1 Open Reading Frame 42 2
  • Cysteine-Rich C-Terminal Protein 1 3
  • NICE-1 3
  • NICE1 4

External Ids for CRCT1 Gene

Previous HGNC Symbols for CRCT1 Gene

  • C1orf42

Previous GeneCards Identifiers for CRCT1 Gene

  • GC01P150756
  • GC01P152486
  • GC01P123860

Summaries for CRCT1 Gene

GeneCards Summary for CRCT1 Gene

CRCT1 (Cysteine-Rich C-Terminal 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CRCT1 Gene

Genomics for CRCT1 Gene

Regulatory Elements for CRCT1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CRCT1 Gene

152,514,502 bp from pter
152,516,010 bp from pter
1,509 bases
Plus strand

Genomic View for CRCT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CRCT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CRCT1 Gene

Proteins for CRCT1 Gene

  • Protein details for CRCT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cysteine-rich C-terminal protein 1
    Protein Accession:
    Secondary Accessions:
    • A4QN00
    • Q6IAD7

    Protein attributes for CRCT1 Gene

    99 amino acids
    Molecular mass:
    9736 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CRCT1 Gene

Proteomics data for CRCT1 Gene at MOPED

Post-translational modifications for CRCT1 Gene

No Post-translational modifications

Other Protein References for CRCT1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CRCT1 Gene

Domains for CRCT1 Gene

Protein Domains for CRCT1 Gene


Suggested Antigen Peptide Sequences for CRCT1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CRCT1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CRCT1 Gene

Function for CRCT1 Gene

Gene Ontology (GO) - Molecular Function for CRCT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CRCT1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CRCT1 Gene

Localization for CRCT1 Gene

Subcellular locations from

Jensen Localization Image for CRCT1 Gene COMPARTMENTS Subcellular localization image for CRCT1 gene
Compartment Confidence
nucleus 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CRCT1 Gene

Pathways for CRCT1 Gene

SuperPathways for CRCT1 Gene

No Data Available

Interacting Proteins for CRCT1 Gene

Gene Ontology (GO) - Biological Process for CRCT1 Gene


No data available for Pathways by source for CRCT1 Gene

Transcripts for CRCT1 Gene

mRNA/cDNA for CRCT1 Gene

(3) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CRCT1 Gene

Cysteine-rich C-terminal 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CRCT1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CRCT1 Gene

No ASD Table

Relevant External Links for CRCT1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CRCT1 Gene

mRNA expression in normal human tissues for CRCT1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CRCT1 Gene

This gene is overexpressed in Esophagus - Mucosa (26.4), Vagina (9.2), and Cervix - Ectocervix (8.1).

Protein differential expression in normal tissues for CRCT1 Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CRCT1 Gene

SOURCE GeneReport for Unigene cluster for CRCT1 Gene Hs.110196

genes like me logo Genes that share expressions with CRCT1: view

Expression partners for CRCT1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CRCT1 Gene

Orthologs for CRCT1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for CRCT1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Crct1 16
Species with no ortholog for CRCT1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CRCT1 Gene

Gene Tree for CRCT1 (if available)
Gene Tree for CRCT1 (if available)

Paralogs for CRCT1 Gene

No data available for Paralogs for CRCT1 Gene

Variants for CRCT1 Gene

Sequence variations from dbSNP and Humsavar for CRCT1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs477621 -- 152,513,776(-) TGTGC(A/G)GGACA upstream-variant-2KB
rs557057 -- 152,514,178(-) CAATA(C/T)ACACA upstream-variant-2KB
rs1053588 -- 152,515,587(-) TGTCG(A/G)CGGCG reference, synonymous-codon
rs1053590 -- 152,515,952(+) AAATG(C/T)CTATT utr-variant-3-prime
rs2282296 -- 152,515,503(-) GAGCC(A/G)CAGCA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for CRCT1 Gene

Variant ID Type Subtype PubMed ID
esv2750810 CNV Gain 17911159
dgv129e1 CNV Complex 17122850
dgv130e1 CNV Complex 17122850
dgv131e1 CNV Complex 17122850
nsv524241 CNV Loss 19592680
nsv518413 CNV Loss 19592680

Relevant External Links for CRCT1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRCT1 Gene

Disorders for CRCT1 Gene

Relevant External Links for CRCT1

Genetic Association Database (GAD)

No disorders were found for CRCT1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CRCT1 Gene

Publications for CRCT1 Gene

  1. Identification of human epidermal differentiation complex (EDC)- encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. (PMID: 11230159) Marenholz I. … Mischke D. (Genome Res. 2001) 2 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. (PMID: 21804549) Torgerson D.G. … Nicolae D.L. (Nat. Genet. 2011) 3 48
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3

Products for CRCT1 Gene

Sources for CRCT1 Gene

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