External Ids for CRB3 Gene
This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for CRB3 Gene
CRB3 (Crumbs Family Member 3) is a Protein Coding gene. Diseases associated with CRB3 include leber congenital amaurosis. Among its related pathways are Cell junction organization and Cell junction organization. GO annotations related to this gene include protein domain specific binding and SH3 domain binding.
UniProtKB/Swiss-Prot for CRB3 Gene
Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions.