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Aliases for CRAMP1 Gene

Aliases for CRAMP1 Gene

  • Cramped Chromatin Regulator Homolog 1 2 3 4 5
  • Hematological And Neurological Expressed 1-Like Protein 3 4
  • CRAMP1L 3 4
  • HN1L 3 4
  • Crm, Cramped-Like (Drosophila) 2
  • Crm (Cramped Drosophila)-Like 2
  • T-Complex Expressed Gene 4 3
  • Protein Cramped-Like 3
  • Crm, Cramped-Like 3
  • C16orf34 4
  • KIAA1426 4
  • TCE4 3

External Ids for CRAMP1 Gene

Previous HGNC Symbols for CRAMP1 Gene


Summaries for CRAMP1 Gene

GeneCards Summary for CRAMP1 Gene

CRAMP1 (Cramped Chromatin Regulator Homolog 1) is a Protein Coding gene. An important paralog of this gene is ENSG00000261732.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CRAMP1 Gene

Genomics for CRAMP1 Gene

Regulatory Elements for CRAMP1 Gene

Enhancers for CRAMP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around CRAMP1 on UCSC Golden Path with GeneCards custom track

Promoters for CRAMP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for CRAMP1 Gene

1,612,325 bp from pter
1,677,908 bp from pter
65,584 bases
Plus strand

Genomic View for CRAMP1 Gene

Genes around CRAMP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CRAMP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CRAMP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CRAMP1 Gene

Proteins for CRAMP1 Gene

  • Protein details for CRAMP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein cramped-like
    Protein Accession:
    Secondary Accessions:
    • A8MZL1
    • B1AJY1
    • Q8NDN1
    • Q9P2C1

    Protein attributes for CRAMP1 Gene

    1269 amino acids
    Molecular mass:
    134718 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAK61288.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAD38692.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for CRAMP1 Gene

Post-translational modifications for CRAMP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CRAMP1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CRAMP1 Gene

Domains & Families for CRAMP1 Gene

Gene Families for CRAMP1 Gene

Protein Domains for CRAMP1 Gene


Suggested Antigen Peptide Sequences for CRAMP1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SANT domain.
  • Belongs to the cramped family.
  • Contains 1 SANT domain.
  • Belongs to the cramped family.
genes like me logo Genes that share domains with CRAMP1: view

Function for CRAMP1 Gene

Gene Ontology (GO) - Molecular Function for CRAMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IBA --
genes like me logo Genes that share ontologies with CRAMP1: view
genes like me logo Genes that share phenotypes with CRAMP1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CRAMP1 Gene

Localization for CRAMP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CRAMP1 Gene

Gene Ontology (GO) - Cellular Components for CRAMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IBA --
genes like me logo Genes that share ontologies with CRAMP1: view

No data available for Subcellular locations from COMPARTMENTS for CRAMP1 Gene

Pathways & Interactions for CRAMP1 Gene

SuperPathways for CRAMP1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CRAMP1 Gene


No data available for Pathways by source and SIGNOR curated interactions for CRAMP1 Gene

Drugs & Compounds for CRAMP1 Gene

No Compound Related Data Available

Transcripts for CRAMP1 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CRAMP1 Gene

No ASD Table

Relevant External Links for CRAMP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CRAMP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of CRAMP1 Gene:

genes like me logo Genes that share expression patterns with CRAMP1: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CRAMP1 Gene

Orthologs for CRAMP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for CRAMP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CRAMP1L 34
  • 83.97 (n)
  • 85.07 (a)
  • 84 (a)
(Canis familiaris)
Mammalia CRAMP1L 34
  • 84.67 (n)
  • 87.25 (a)
  • 82 (a)
(Mus musculus)
Mammalia Cramp1l 34
  • 81.7 (n)
  • 84.26 (a)
Cramp1l 16
Cramp1l 35
  • 82 (a)
(Pan troglodytes)
Mammalia CRAMP1L 34
  • 97.68 (n)
  • 97 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Cramp1l 34
  • 81.63 (n)
  • 83.87 (a)
(Monodelphis domestica)
Mammalia CRAMP1L 35
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 79 (a)
(Gallus gallus)
Aves CRAMP1L 34
  • 72.3 (n)
  • 75.02 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cramp1l 34
  • 64.69 (n)
  • 65.43 (a)
(Danio rerio)
Actinopterygii cramp1l 34
  • 63.36 (n)
  • 62.28 (a)
fruit fly
(Drosophila melanogaster)
Insecta crm 35
  • 23 (a)
(Caenorhabditis elegans)
Secernentea R151.8 35
  • 20 (a)
Species where no ortholog for CRAMP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CRAMP1 Gene

Gene Tree for CRAMP1 (if available)
Gene Tree for CRAMP1 (if available)

Paralogs for CRAMP1 Gene

Paralogs for CRAMP1 Gene

genes like me logo Genes that share paralogs with CRAMP1: view

Variants for CRAMP1 Gene

Sequence variations from dbSNP and Humsavar for CRAMP1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs3169425 -- 1,632,280(-) ATGCT(C/T)GCTGG reference, synonymous-codon
rs3178656 -- 1,663,512(+) TAAGA(C/T)CAGGG intron-variant
rs3178659 -- 1,663,757(+) AACCA(C/T)GGATC intron-variant
rs3743511 -- 1,655,080(+) CCTGC(A/G)GACGC intron-variant
rs3830783 -- 1,667,646(+) GAACT(-/TAGCGCTCTGGAAGAACT)CAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CRAMP1 Gene

Variant ID Type Subtype PubMed ID
dgv4855n54 CNV loss 21841781
dgv4856n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
esv3637620 CNV loss 21293372
esv3637621 CNV loss 21293372
nsv1051692 CNV loss 25217958
nsv1143803 CNV deletion 24896259
nsv428317 CNV gain 18775914
nsv518641 CNV loss 19592680
nsv827496 CNV gain 20364138
nsv827497 CNV gain 20364138
nsv833118 CNV loss 17160897

Variation tolerance for CRAMP1 Gene

Residual Variation Intolerance Score: 13.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.78; 58.08% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CRAMP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRAMP1 Gene

Disorders for CRAMP1 Gene

Relevant External Links for CRAMP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CRAMP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CRAMP1 Gene

Publications for CRAMP1 Gene

  1. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3 4 65
  2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 3 4 65
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen J.V. … Mann M. (Sci. Signal. 2010) 4 65

Products for CRAMP1 Gene

Sources for CRAMP1 Gene

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