Aliases for CRABP2 Gene
External Ids for CRABP2 Gene
Previous GeneCards Identifiers for CRABP2 Gene
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]
GeneCards Summary for CRABP2 Gene
CRABP2 (Cellular Retinoic Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with CRABP2 include Embryonal Carcinoma and Leukemia, Acute Promyelocytic, Somatic. Among its related pathways are Vitamin A and Carotenoid Metabolism and RNA Polymerase II Transcription Initiation And Promoter Clearance. GO annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP1.
UniProtKB/Swiss-Prot for CRABP2 Gene
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.