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CPXM2 Gene

protein-coding   GIFtS: 51
GCID: GC10M125462

Carboxypeptidase X (M14 Family), Member 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Carboxypeptidase X (M14 Family), Member 21 2     Carboxypeptidase Hlo2
Cytosolic Carboxypeptidase1 2     Carboxypeptidase-Like Protein X22
4632435C11Rik2     Inactive Carboxypeptidase-Like Protein X22
CPX22     EC 3.4.178
UNQ6762     EC 3.4.17.38

External Ids:    HGNC: 269771   Entrez Gene: 1195872   Ensembl: ENSG000001218987   UniProtKB: Q8N4363   

Export aliases for CPXM2 gene to outside databases

Previous GC identifers: GC10M125495 GC10M119120


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CPXM2 Gene:
CPXM2 (carboxypeptidase X (M14 family), member 2) is a protein-coding gene. GO annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is CPZ.

UniProtKB/Swiss-Prot: CPXM2_HUMAN, Q8N436
Function: May be involved in cell-cell interactions




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CPXM2 gene promoter:
         Max1   TBP   RFX1   CUTL1   GATA-2   S8   FOXC1   TFIID   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCPXM2 promoter sequence
   Search Chromatin IP Primers for CPXM2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CPXM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.13   Ensembl cytogenetic band:  10q26.13   HGNC cytogenetic band: 10q26

CPXM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPXM2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M125462:  view genomic region     (about GC identifiers)

Start:
125,465,723 bp from pter      End:
125,699,783 bp from pter
Size:
234,061 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CPXM2_HUMAN, Q8N436 (See protein sequence)
Recommended Name: Inactive carboxypeptidase-like protein X2 precursor  
Size: 756 amino acids; 85870 Da
Caution: Although related to peptidase M14 family, lacks the active sites residues and zinc-binding sites,
suggesting that it has no carboxypeptidase activity
Secondary accessions: B4E3Q2

Explore the universe of human proteins at neXtProt for CPXM2: NX_Q8N436

Explore proteomics data for CPXM2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn231, Asn241, Asn281, Asn337, Asn491
  • 2 DME Specific Peptides for CPXM2 (Q8N436)
     GDYWRLL  YLHTNCFE 


    See CPXM2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_937791.2  
    ENSEMBL proteins: 
     ENSP00000241305  

    CPXM2 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CPXM2 

     
    antibodies-online proteins for CPXM2 (4 products) 

     
    antibodies-online peptides for CPXM2

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    antibodies-online antibodies for CPXM2 (36 products) 

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    antibodies-online kits for CPXM2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: Carboxypeptidase X (M14 family), member 2
    Metallocarboxypeptidases

    5 InterPro protein domains:
     IPR008969 CarboxyPept-like_regulatory
     IPR014766 CarboxyPept_regulatory_dom
     IPR008979 Galactose-bd-like
     IPR000834 Peptidase_M14
     IPR000421 Coagulation_fac_5/8-C_type_dom

    Graphical View of Domain Structure for InterPro Entry Q8N436

    ProtoNet protein and cluster: Q8N436

    2 Blocks protein domains:
    IPB000421 Coagulation factor 5/8 type C domain (FA58C)
    IPB000834 Zinc carboxypeptidase A metalloprotease (M14)


    UniProtKB/Swiss-Prot: CPXM2_HUMAN, Q8N436
    Similarity: Belongs to the peptidase M14 family
    Similarity: Contains 1 F5/8 type C domain


    Find genes that share domains with CPXM2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CPXM2_HUMAN, Q8N436
    Function: May be involved in cell-cell interactions

         Enzyme Numbers (IUBMB): EC 3.4.172 EC 3.4.17.32

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004181metallocarboxypeptidase activity IEA--
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with CPXM2           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Cpxm2 (no phenotypes)

    Find genes that share phenotypes with CPXM2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cpxm2tm1Lex for CPXM2

       genOway: Develop your customized and physiologically relevant rodent model for CPXM2

    miRNA
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    Block miRNA regulation of human, mouse, rat CPXM2 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CPXM2:
    hsa-miR-183* hsa-miR-653 hsa-miR-1261 hsa-miR-1827
    SwitchGear 3'UTR luciferase reporter plasmidCPXM2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CPXM2
    Predesigned siRNA for gene silencing in human, mouse, rat CPXM2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: CPXM2 (NM_198148)
    Sino Biological Human cDNA Clone for CPXM2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPXM2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CPXM2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPXM2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CPXM2_HUMAN, Q8N436: Secreted (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular4
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0031012colocalizes with extracellular matrix IDA--

    Find genes that share ontologies with CPXM2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CPXM2
    Interactions:

        Search GeneGlobe Interaction Network for CPXM2

    1 Interacting protein for CPXM2 (Q8N4363) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD9O151983I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0007155cell adhesion IEA--

    Find genes that share ontologies with CPXM2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CPXM2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CPXM2 gene: 
    NM_198148.2  

    Unigene Cluster for CPXM2:

    Carboxypeptidase X (M14 family), member 2
    Hs.656887  [show with all ESTs]
    Unigene Representative Sequence: AY358565
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368854(uc001lhj.3) ENST00000241305(uc001lhk.1) ENST00000481775

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CPXM2 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CPXM2:
    hsa-miR-183* hsa-miR-653 hsa-miR-1261 hsa-miR-1827
    SwitchGear 3'UTR luciferase reporter plasmidCPXM2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CPXM2
    Predesigned siRNA for gene silencing in human, mouse, rat CPXM2
    Clone
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    OriGene clones in human, mouse for CPXM2 (see all 7)
    OriGene ORF clones in mouse, rat for CPXM2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CPXM2 (NM_198148)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPXM2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPXM2
    Primer
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    OriGene qPCR primer pairs and template standards for CPXM2
    OriGene qSTAR qPCR primer pairs in human, mouse for CPXM2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CPXM2
      QuantiTect SYBR Green Assays in human, mouse, rat CPXM2
      QuantiFast Probe-based Assays in human, mouse, rat CPXM2

    Additional mRNA sequence: 

    AK296365.1 AK300506.1 AK304023.1 AK304814.1 AL833732.1 AY358565.1 BC036789.1 BC137492.1 
    BC146862.1 

    7 DOTS entries:

    DT.313496  DT.97840995  DT.100775993  DT.121263860  DT.40217909  DT.91814375  DT.91684305 

    Selected AceView cDNA sequences (see all 100):

    BQ018181 AI366508 BI492793 BM707193 AI300011 AA045145 BC036789 BM717146 
    AI041966 BQ007818 CA312019 AI143223 AY358565 W81559 W81558 AW024746 
    AA045254 BM727787 NM_198148 AW513612 BQ009856 AW029071 CN479157 BM673214 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CPXM2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:        -           -     -           -     -                                         -           -                                 
    SP2:                    -     -           -     -                                                                                       
    SP3:                                      -     -                                                                                       
    SP4:                    -     -                                                                                                         
    SP5:                                                                                                                                    


    ECgene alternative splicing isoforms for CPXM2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CPXM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTTGGCCTC
    CPXM2 Expression
    About this image


    CPXM2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Brain (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus
    CPXM2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CPXM2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656887
        Custom PCR Arrays for CPXM2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPXM2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CPXM2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cpxm21 , 5 carboxypeptidase X 2 (M14 family)1, 5 85.79(n)1
    90.19(a)1
      7 (75.60 cM)5
    559871  NM_018867.51  NP_061355.31 
     1320428165 
    chicken
    (Gallus gallus)
    Aves CPXM21 carboxypeptidase X (M14 family), member 2 75.8(n)
    81.3(a)
      423951  XM_421810.4  XP_421810.4 
    lizard
    (Anolis carolinensis)
    Reptilia CPXM26
    carboxypeptidase X (M14 family), member 2
    89(a)
    1 ↔ 1
    3(60819892-60888936)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cpxm21 carboxypeptidase X (M14 family), member 2 71.11(n)
    75.98(a)
      100127849  XM_002937805.2  XP_002937851.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7933081 adipocyte enhancer-binding protein 1-like 63.14(n)
    61.34(a)
      793308  XM_001920851.3  XP_001920886.2 


    ENSEMBL Gene Tree for CPXM2 (if available)
    TreeFam Gene Tree for CPXM2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CPXM2 gene
    CPZ2  CPE2  AEBP12  CPN12  CPD2  CPM2  CPXM12  
    9 SIMAP similar genes for CPXM2 using alignment to 2 protein entries:     CPXM2_HUMAN (see all proteins):
    DKFZp666J235    CPXM1    CPE    F8C    AEBP1    CPZ
    CPN1    CPM    CNTNAP2

    Find genes that share paralogs with CPXM2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CPXM2 (see all 3376)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1466339901,2
    C,Funtested1125557567(+) TATGCG/AGATGT 2 /R /C mis11Minor allele frequency- A:0.00NA 4552
    rs1444664071,2
    --125504735(+) TCTGCC/TTACCT 1 -- int10--------
    rs122444401,2
    --125504741(+) tacctC/Tggcct 1 -- int10--------
    rs1885617491,2
    --125504753(+) CCAAAC/GTGCTG 1 -- int10--------
    rs1923520311,2
    C--125504823(+) GTTATC/GACAGA 1 -- int10--------
    rs79182571,2
    C,F,A,H--125504915(+) AAGCTG/ATATGA 1 -- int127Minor allele frequency- A:0.25NS EA NA WA CSA 2763
    rs1849438041,2
    --125504916(+) AGCTGG/TATGAG 1 -- int10--------
    rs1866534131,2
    C--125504983(+) ACAAGA/TGTCTC 1 -- int10--------
    rs1136216181,2
    C--125505169(+) ATTTGC/TTTTAT 1 -- ut312Minor allele frequency- T:0.03NA 122
    rs32145381,2
    C--125505174(-) AAAAA-/ATAAAG 1 -- ut31 trp30--------

    HapMap Linkage Disequilibrium report for CPXM2 (125465723 - 125699783 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CPXM2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2742550CNV Deletion23290073
    esv2742528CNV Deletion23290073
    esv2742539CNV Deletion23290073
    esv2742517CNV Deletion23290073
    esv2220029CNV Deletion18987734
    esv2742506CNV Deletion23290073
    nsv820023CNV Loss19587683
    esv27822CNV Loss19812545
    nsv25320CNV Loss16902084
    nsv832011CNV Gain+Loss17160897

    Human Gene Mutation Database (HGMD): CPXM2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CPXM2
    DNA2.0 Custom Variant and Variant Library Synthesis for CPXM2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with CPXM2           About GenesLikeMe

    Genetic Association Database (GAD): CPXM2
    Human Genome Epidemiology (HuGE) Navigator: CPXM2 (2 documents)

    Export disorders for CPXM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CPXM2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CPXM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (Genome Res. 2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Identification of mouse CPX-2, a novel member of the metallocarboxypeptidase gene family: cDNA cloning, mRNA distribution, and protein expression and characterization. (PubMed id 9809751)1 Xin X....Fricker L.D. (DNA Cell Biol. 1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 119587 HGNC: 26977 AceView: CPXM2 Ensembl:ENSG00000121898 euGenes: HUgn119587
    ECgene: CPXM2 H-InvDB: CPXM2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CPXM2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CPXM2 gene:
    Search GeneIP for patents involving CPXM2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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