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Aliases for CPXCR1 Gene

Aliases for CPXCR1 Gene

  • CPX Chromosome Region, Candidate 1 2 3 5
  • Cancer/Testis Antigen 77 2 3 4
  • CT77 3 4

External Ids for CPXCR1 Gene

Previous GeneCards Identifiers for CPXCR1 Gene

  • GC0XP083274
  • GC0XP084971
  • GC0XP086037
  • GC0XP086774
  • GC0XP087808
  • GC0XP088002
  • GC0XP081584

Summaries for CPXCR1 Gene

Entrez Gene Summary for CPXCR1 Gene

  • This gene is one of several genes identified in a region of the X chromosome associated with an X-linked cleft palate (CPX) disorder. The encoded protein contains a motif similar to a motif found in zinc-finger proteins. Mutation analysis of this gene has not revealed any mutation which causes the CPX disorder. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]

GeneCards Summary for CPXCR1 Gene

CPXCR1 (CPX Chromosome Region, Candidate 1) is a Protein Coding gene. Diseases associated with CPXCR1 include X-Linked Cleft Palate And Ankyloglossia.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CPXCR1 Gene

Genomics for CPXCR1 Gene

Regulatory Elements for CPXCR1 Gene

Enhancers for CPXCR1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CPXCR1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CPXCR1 Gene

88,747,225 bp from pter
88,754,785 bp from pter
7,561 bases
Plus strand

Genomic View for CPXCR1 Gene

Genes around CPXCR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CPXCR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CPXCR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CPXCR1 Gene

Proteins for CPXCR1 Gene

  • Protein details for CPXCR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    CPX chromosomal region candidate gene 1 protein
    Protein Accession:
    Secondary Accessions:
    • B2R9F9
    • D3DTE7
    • Q96RS3

    Protein attributes for CPXCR1 Gene

    301 amino acids
    Molecular mass:
    34727 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CPXCR1 Gene

Proteomics data for CPXCR1 Gene at MOPED

Post-translational modifications for CPXCR1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CPXCR1 Gene

No data available for DME Specific Peptides for CPXCR1 Gene

Domains & Families for CPXCR1 Gene

Protein Domains for CPXCR1 Gene


Suggested Antigen Peptide Sequences for CPXCR1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CPXCR1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CPXCR1 Gene

Function for CPXCR1 Gene

genes like me logo Genes that share phenotypes with CPXCR1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CPXCR1 Gene

Localization for CPXCR1 Gene

Subcellular locations from

Jensen Localization Image for CPXCR1 Gene COMPARTMENTS Subcellular localization image for CPXCR1 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CPXCR1 Gene

Pathways & Interactions for CPXCR1 Gene

SuperPathways for CPXCR1 Gene

No Data Available

Interacting Proteins for CPXCR1 Gene

Selected Interacting proteins: Q8N123-CPXCR_HUMAN for CPXCR1 Gene via MINT

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CPXCR1 Gene


No data available for Pathways by source and SIGNOR curated interactions for CPXCR1 Gene

Drugs & Compounds for CPXCR1 Gene

No Compound Related Data Available

Transcripts for CPXCR1 Gene

mRNA/cDNA for CPXCR1 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CPXCR1 Gene

CPX chromosome region, candidate 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CPXCR1 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP2: -

Relevant External Links for CPXCR1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CPXCR1 Gene

mRNA expression in normal human tissues for CPXCR1 Gene

mRNA differential expression in normal tissues according to GTEx for CPXCR1 Gene

This gene is overexpressed in Testis (x52.2).

Protein differential expression in normal tissues from HIPED for CPXCR1 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CPXCR1 Gene

SOURCE GeneReport for Unigene cluster for CPXCR1 Gene Hs.458292

mRNA Expression by UniProt/SwissProt for CPXCR1 Gene

Tissue specificity: Expressed in a variety of fetal tissues.
genes like me logo Genes that share expression patterns with CPXCR1: view

Protein tissue co-expression partners for CPXCR1 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for CPXCR1 Gene

Orthologs for CPXCR1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for CPXCR1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Cpxcr1 35
  • 63.82 (n)
  • 43.34 (a)
Cpxcr1 16
Cpxcr1 36
  • 39 (a)
(Pan troglodytes)
Mammalia CPXCR1 35
  • 99.22 (n)
  • 98.01 (a)
  • 98 (a)
Species with no ortholog for CPXCR1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CPXCR1 Gene

Gene Tree for CPXCR1 (if available)
Gene Tree for CPXCR1 (if available)

Paralogs for CPXCR1 Gene

No data available for Paralogs for CPXCR1 Gene

Variants for CPXCR1 Gene

Sequence variations from dbSNP and Humsavar for CPXCR1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs5940915 - 88,753,422(+) GAGTT(A/C)TCCTA reference, missense
rs5984611 - 88,753,806(+) AACTC(A/G)TTTTC reference, missense
rs747844870 -- 88,754,332(+) TTGGG(A/G)TAAAT utr-variant-3-prime
rs747893236 -- 88,751,208(+) ATTTA(A/G)TGCTA intron-variant
rs747992351 -- 88,750,237(+) TTTGA(G/T)ATACG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CPXCR1 Gene

Variant ID Type Subtype PubMed ID
nsv515219 CNV Loss 21397061

Variation tolerance for CPXCR1 Gene

Residual Variation Intolerance Score: 71.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.52; 77.74% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CPXCR1 Gene

Disorders for CPXCR1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CPXCR1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
x-linked cleft palate and ankyloglossia
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CPXCR1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CPXCR1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CPXCR1 Gene

Publications for CPXCR1 Gene

  1. Physical and transcriptional mapping of the X-linked cleft palate and ankyloglossia (CPX) critical region. (PMID: 11499681) Braybrook C. … Stanier P. (Hum. Genet. 2001) 2 3 4 67
  2. Genetically distinct subsets within ANCA-associated vasculitis. (PMID: 22808956) Lyons P.A. … Smith K.G. (N. Engl. J. Med. 2012) 3
  3. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CPXCR1 Gene

Sources for CPXCR1 Gene