CPSF6 Gene
protein-coding GIFtS: 55
GCID: GC12P069633
|
|
cleavage and polyadenylation specific factor 6, 68kDa(Previous names: cleavage and polyadenylation specific factor 6, 68kD subunit...)
| |
Aliases
for CPSF6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cleavage And Polyadenylation Specific Factor 6, 68kDa1 2 | | Protein HPBRII-4/72 3 | | CFIM681 2 3 | | CPSF 68 KDa Subunit2 3 | | CFIM1 2 5 | | Cleavage And Polyadenylation Specific Factor 6, 68kD Subunit1 | | HPBRII-41 2 | | Cleavage And Polyadenylation Specificity Factor Subunit 62 | | HPBRII-71 2 | | Pre-MRNA Cleavage Factor I, 68kD Subunit2 | | Cleavage And Polyadenylation Specificity Factor 68 KDa Subunit2 3 | | Pre-MRNA Cleavage Factor Im (68kD)2 | | Pre-MRNA Cleavage Factor Im 68 KDa Subunit2 3 | | CFIm683 |
Export aliases for CPSF6 gene to outside databasesPrevious GC identifers: GC12M069604 GC12P069573 GC12P069350 GC12P067919 |
Summaries
for CPSF6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CPSF6:
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylationprocessing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' endprocessing complex and facilitates the recruitment of other processing factors. The cleavage factor complex iscomposed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent ofspliceosomal proteins. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CPSF6_HUMAN, Q16630Function: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involvedin association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds tocleavage and polyadenylation RNA substrates and promotes RNA looping
Gene Wiki entry for CPSF6
|
Genomic Views
for CPSF6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CPSF6 gene promoter:
NF-1/L NF-1 Elk-1 MAZR AML1a E47 HEN1 STAT3 Cart-1 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CPSF6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPSF6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q15 Ensembl cytogenetic band: 12q15 HGNC cytogenetic band: 12q15CPSF6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P069633: view genomic region
(about GC identifiers)
Start:
|
69,633,317 bp from pter |
End:
|
69,668,138 bp from pter |
Size:
|
34,822 bases |
Orientation:
|
plus strand |
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Proteins
for CPSF6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CPSF6_HUMAN, Q16630 (See
protein sequence)Recommended Name: Cleavage and polyadenylation specificity factor subunit 6 Size: 551 amino acids; 59210 Da
Subunit: Component of the cleavage factor Im (CFIm) complex, composed at least of NUDT21/CPSF5 and CPSF6 or CPSF7.Within the cleavage factor Im complex, the NUDT21/CPSF5 homodimer is at the core of a heterotetramer, and is claspedby two additional subunits (CPSF6 or CPSF7). Interacts with NUDT21/CPSF5, SFRS3, SFRS7, SNRNP70 and TRA2B/SFRS10
Subcellular location: Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, calledparaspeckles
5 PDB 3D structures from  and Proteopedia  for CPSF6:3P5T (3D)
3P6Y (3D)
3Q2S (3D)
3Q2T (3D)
4B4N (3D)
Secondary accessions: A8K7K9 Q53ES1 Q9BSJ7 Q9BW18Alternative splicing: 3 isoforms: Q16630-1 Q16630-2 Q16630-3 Explore the universe of human proteins at neXtProt for CPSF6: NX_Q16630
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16630
CPSF6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008938.2
ENSEMBL proteins: ENSP00000391774 ENSP00000446670 ENSP00000391437 ENSP00000266679 ENSP00000450206 Reactome Protein details: Q16630
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
CPSF6 for ontologies About GeneDecksing
CPSF6 Antibody Products:
Assay Products for CPSF6: |
Protein
Domains /
Families
for CPSF6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CPSF6 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16630ProtoNet protein and cluster: Q16630 1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
UniProtKB/Swiss-Prot: CPSF6_HUMAN, Q16630Similarity: Belongs to the RRM CPSF6/7 familySimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for CPSF6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CPSF6_HUMAN, Q16630Function: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involvedin association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds tocleavage and polyadenylation RNA substrates and promotes RNA looping
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPSF6 (see all 3)
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPSF6 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
CPSF6 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CPSF6:
|
Pathways & Interactions
for CPSF6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by FGFR1 mutants | | | 2 | Disease | | | 3 | mRNA surveillance pathway | | | 4 | Signaling by FGFR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/6 
Reactome Pathways for CPSF6 (see all 6)
1 
Kegg Pathway (Kegg details for CPSF6):
CPSF6 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CPSF6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/100 Interacting proteins for CPSF6 (Q166301, 2, 3 ENSP000003917744) via UniProtKB, MINT, STRING, and/or I2D (see all 100)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| KLHL12 | Q53G592, 3, ENSP000003562304 | MINT-67222 I2D:
score=5 STRING: ENSP00000356230 | | WWP2 | O003082, 3, ENSP000003482834 | MINT-67985 I2D:
score=5 STRING: ENSP00000348283 | | RELB | Q012012, 3 | MINT-49005 I2D:
score=2 | | WWP1 | Q9H0M01, 2, 3, ENSP000002654284 | EBI-740029,EBI-742157 MINT-66359 I2D:
score=6 STRING: ENSP00000265428 | | PLSCR1 | O151621, 2, 3, ENSP000003454944 | EBI-740029,EBI-740019 MINT-66053 I2D:
score=6 STRING: ENSP00000345494 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
CPSF6 for ontologies About GeneDecksing
|
Drugs & Compounds
for CPSF6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CPSF6
Search CenterWatch for drugs/clinical trials and news about CPSF6
|
Transcripts
for CPSF6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CPSF6 gene: NM_007007.2 Unigene Cluster for CPSF6: Cleavage and polyadenylation specific factor 6, 68kDa Hs.369606 [show with all ESTs]Unigene Representative Sequence: NM_0070077 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000435070(uc001sut.4 uc001suu.4 uc010stk.2) ENST00000550075
ENST00000456847 ENST00000266679 ENST00000550987 ENST00000551516 ENST00000547486
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPSF6 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPSF6 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CPSF6 (NM_007007) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CPSF6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPSF6 |
Additional cDNA sequence: AK021534.1 AK021833.1 AK093765.1 AK098338.1 AK223568.1 AK292024.1 AK299928.1 BC000714.2 BC005000.1 X67337.1 18 DOTS entries: DT.100028557 DT.91770904 DT.70103416 DT.91981183 DT.97773721 DT.95126043 DT.121189687 DT.86805461 DT.100806125 DT.121189683 DT.121189715 DT.91770901 DT.91770902 DT.417884 DT.121189720 DT.91770909 DT.95126038 DT.95147508 24/359 AceView cDNA sequences (see all 359): BM968382 BQ924444 BM758741 R44870 BF439464 AA682629 BU675035 AA884612 BM716550 BP368706 AU125770 AL556891 C03053 AV728580 BM766794 AI146408 AV727306 CR623508 AA354466 H88941 BM758309 CF141943 CA942912 BU844439
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CPSF6 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 |
|---|
|
| SP1: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CPSF6
|
Expression
for CPSF6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CPSF6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTATTTATCT
About this image
See CPSF6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CPSF6
SOURCE GeneReport for Unigene cluster: Hs.369606
SABiosciences Custom PCR Arrays for CPSF6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPSF6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CPSF6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPSF6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPSF6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPSF6 |
Orthologs
for CPSF6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CPSF6 gene from 8/28 species (see all 28) About this table
ENSEMBL Gene Tree for CPSF6 (if available)
TreeFam Gene Tree for CPSF6 (if available) |
Paralogs
for CPSF6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CPSF6 gene
- CPSF72 SF3B42 MAPK1IP1L2
1 SIMAP similar gene for CPSF6 using alignment to 5 protein entries: CPSF6_HUMAN (see all proteins):CPSF7
CPSF6 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CPSF6
PGOHUM00000234236
|
Genomic Variants
for CPSF6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CPSF6 (69633317 - 69668138 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CPSF6: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPSF6 |
|
Disorders
/ Diseases
for CPSF6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CPSF6 for disorders About GeneDecksing
OMIM gene information: 604979
OMIM disorders: --
6  diseases for CPSF6: About MalaCardswiskott-aldrich syndrome synovial sarcoma sarcoma ataxia
tuberculosis mycobacterium tuberculosis
Export disorders for CPSF6 gene to outside databases
|
Publications
for CPSF6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CPSF6 gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with CPSF6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. (PubMed id 9659921)1, 2, 3 Rueegsegger U.... Keller W. (1998)
- Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping. (PubMed id 21295486)1, 2 Yang Q.... Doublie S. (2011)
- Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation. (PubMed id 20695905)1, 2 Kim S....Yamaguchi Y. (2010)
- Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit. (PubMed id 17267687)1, 3 Cardinale S....Barabino S.M. (2007)
- Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. (PubMed id 15169763)1, 2 Dettwiler S.... Barabino S.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im. (PubMed id 14690600)1, 2 Brown K.M. and Gilmartin G.M. (2003)
- Association of polyadenylation cleavage factor I with U1 snRNP. (PubMed id 14561889)1, 2 Awasthi S. and Alwine J.C. (2003)
- Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors. (PubMed id 8626397)1, 2 Rueegsegger U.... Keller W. (1996)
|
External Searches for CPSF6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CPSF6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CPSF6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CPSF6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CPSF6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CPSF6 gene:
Search GeneIP for patents involving CPSF6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CPSF6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CPSF6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPSF6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPSF6 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CPSF6 | | OriGene 3'-UTR Clone for CPSF6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPSF6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPSF6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CPSF6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CPSF6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPSF6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPSF6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPSF6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPSF6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPSF6 |
| |
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| | | | Search Tocris compounds for CPSF6 |
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 | | | CPSF6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPSF6 |
|  |  |  | | | | Search ThermoFisher Antibodies for CPSF6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPSF6 |
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