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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CPQ Gene

protein-coding   GIFtS: 44
GCID: GC08P097657

carboxypeptidase Q
 Explore 57 diseases affiliated with
CPQ via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CPQ    

Aliases
for CPQ gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Carboxypeptidase Q1 2     Aminopeptidase1
PGCP1 2 3     Ser-Met Dipeptidase2
LDP1 2     EC 3.4.17.-3
Lysosomal Dipeptidase2 3     LCH13
Plasma Glutamate Carboxypeptidase2 3     

External Ids:    HGNC: 169101   Entrez Gene: 104042   Ensembl: ENSG000001043247   UniProtKB: Q9Y6463   

Export aliases for CPQ gene to outside databases


Summaries
for CPQ gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: CBPQ_HUMAN, Q9Y646
Function: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the
hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine
hormone from its thyroglobulin (Tg) precursor




Genomic Views
for CPQ gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CPQ
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CPQ promoter sequence
   Search SABiosciences Chromatin IP Primers for CPQ

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPQ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.2   Ensembl cytogenetic band:  8q22.1   HGNC cytogenetic band: 8q22.2

CPQ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPQ gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P097657:  view genomic region     (about GC identifiers)

Start:
 97,657,455 bp from pter      End:
 98,161,882 bp from pter
Size:
 504,428 bases      Orientation:
 plus strand

Proteins
for CPQ gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CBPQ_HUMAN, Q9Y646 (See protein sequence)
Recommended Name: Carboxypeptidase Q precursor  
Size: 472 amino acids; 51888 Da
Subunit: Homodimer. The monomeric form is inactive while the homodimer is active
Subcellular location: Endoplasmic reticulum. Golgi apparatus. Lysosome (By similarity). Secreted. Note=Secretion is
stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin (By similarity)
Sequence caution: Sequence=AAD31418.1; Type=Frameshift; Positions=446;
Secondary accessions: B2RD88 Q8NBZ1 Q9UNM8 Q9Y5X6

Explore the universe of human proteins at neXtProt for CPQ: NX_Q9Y646

Post-translational modifications:

  • N-glycosylated. The secreted form is modified by hybrid or complex type oligosaccharide chains (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y646

    • CPQ Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_057218.1  
    ENSEMBL proteins: 
     ENSP00000220763   ENSP00000431024   ENSP00000429146   ENSP00000431114   ENSP00000429934  
     ENSP00000429134  

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    Novus Biologicals CPQ Protein
    Novus Biologicals CPQ Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005737cytoplasm IDA10206990
    GO:0005764lysosome ISS--
    GO:0005783endoplasmic reticulum ISS--
    GO:0005794Golgi apparatus ISS--


    CPQ for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CPQ gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CPQ for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007484 Peptidase_M28

    Graphical View of Domain Structure for InterPro Entry Q9Y646

    ProtoNet protein and cluster: Q9Y646

    UniProtKB/Swiss-Prot: CBPQ_HUMAN, Q9Y646
    Similarity: Belongs to the peptidase M28 family


    Function
    for CPQ gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CBPQ_HUMAN, Q9Y646
    Function: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the
    hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine
    hormone from its thyroglobulin (Tg) precursor
    Induction: Up-regulated in the majority of hepatitis C virus-associated hepatocellular carcinoma

    Enzyme Number (IUBMB): EC 3.4.17.-1

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPQ
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    SwitchGear 3'UTR luciferase reporter plasmid: CPQ 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPQ (see all 3)
    Browse OriGene siRNA
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    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPQ 

    Cell Line
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    Search LifeMap BioReagents cell lines for CPQ

    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004180carboxypeptidase activity IEA--
    GO:0042803protein homodimerization activity IDA12675526
    GO:0046872metal ion binding IEA--
    GO:0070573metallodipeptidase activity IDA10206990


    CPQ for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CPQ:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for CPQ gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPQ

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for CPQ (Q9Y6463 ENSP000002207634) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLC2A4P146723I2D: score=1 
    SIRT3ENSP000003721914STRING: ENSP00000372191
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IDA10206990
    GO:0006590thyroid hormone generation ISS--
    GO:0042246tissue regeneration ISS--
    GO:0043171peptide catabolic process IDA10206990


    CPQ for ontologies           About GeneDecksing



    Drugs & Compounds
    for CPQ gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CPQ for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CPQ
    10/94 Novoseek chemical compound relationships for CPQ gene (see all 94)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    bestatin 95.6 120 1846352 (3), 18823778 (3), 9355022 (3), 1733647 (3) (see all 80)
    amastatin 88.4 15 1282624 (1), 8395230 (1), 15783133 (1), 7575672 (1) (see all 15)
    probestin 86.6 3 11209758 (1), 9813136 (1), 1417460 (1)
    leuhistin 81.6 1 8820902 (1)
    actinonin 79.7 2 14738154 (1), 9813136 (1)
    alanine-p-nitroanilide 76.2 1 8519802 (1)
    leucine 73.5 49 8860437 (2), 10220586 (2), 14599351 (2), 8444149 (1) (see all 39)
    puromycin 72.1 13 11955816 (2), 9819290 (2), 1680182 (1), 1515063 (1) (see all 11)
    thiorphan 70.2 1 10825373 (1)
    arphamenine b 68.9 2 10374877 (1), 8820902 (1)

    Search CenterWatch for drugs/clinical trials and news about CPQ / CBPQ 

    Transcripts
    for CPQ gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CPQ gene: 
    NM_016134.2  

    Unigene Cluster for CPQ:

    Carboxypeptidase Q
    Hs.156178  [show with all ESTs]
    Unigene Representative Sequence: NM_016134
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000220763(uc010mbe.2 uc003yhw.3) ENST00000519900 ENST00000517742
    ENST00000525310 ENST00000519484 ENST00000521142 ENST00000522617 ENST00000532528
    ENST00000529551

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPQ
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    SwitchGear 3'UTR luciferase reporter plasmid: CPQ 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPQ
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPQ

    Additional cDNA sequence: 

    AF107833.1 AF107834.1 AF119386.1 AK075132.1 AK296013.1 AK304008.1 AK315447.1 BC012019.1 
    BC020689.1 

    12 DOTS entries:

    DT.452074  DT.100795333  DT.91755837  DT.95110180  DT.100795336  DT.100795332  DT.120639329  DT.120639341 
    DT.120639470  DT.91755830  DT.91755846  DT.100645102 

    24/256 AceView cDNA sequences (see all 256):

    BU734414 AA410735 CA414510 BF476110 N95081 BX355940 AI422285 BF476853 
    BI911772 BQ019250 AI032982 R05717 BU677292 AI361429 BU625199 D57208 
    AW440965 CA445512 AA329616 BX360507 AW474992 BM710601 BX439467 BI754468 

    GeneLoc Exon Structure


    Expression
    for CPQ gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CPQ expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTTCTGTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CPQ expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerMature Horizontal CellsHorizontal, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CPQ Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CPQ

    SOURCE GeneReport for Unigene cluster: Hs.156178

    UniProtKB/Swiss-Prot: CBPQ_HUMAN, Q9Y646
    Tissue specificity: Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles,
    liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level)

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    In Situ
    Assay Products:     
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    Orthologs
    for CPQ gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CPQ gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cpq5
    Pgcp1    		 plasma glutamate carboxypeptidase1, 5 87.45(n)1
    88.09(a)1    		   15 (13.74 cM)5
    543811  NM_018755.21  NP_061225.21 
     330831295 
    chicken
    (Gallus gallus)    		 Aves CPQ1 carboxypeptidase Q 72.57(n)
    74.2(a)    		   420238  XM_418350.3  XP_418350.3 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 3)    		 --
    		 70(a)
    58(a)
    (see all 3)    		 many → 1
    many → 1
    (see all 3)    		 4(20298122-20330468)
    AAWZ02039528(396-1219)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.142522 Xenopus laevis transcribed sequence with weak similarity more 70.35(n)    BX850772.1 
    rainbow trout
    (Oncorhynchus mykiss)    		 Actinopterygii Omy.2242 Oncorhynchus mykiss transcribed sequence with moderate more 74.17(n)    BX319373.1 
    mosquito
    (Anopheles gambiae)    		 Insecta AgaP_AGAP0012641 AGAP001264-PA 54.34(n)
    49.32(a)    		   1281913  XM_321888.4  XP_321888.3 


    ENSEMBL Gene Tree for CPQ (if available)
    TreeFam Gene Tree for CPQ (if available) 

    Paralogs
    for CPQ gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for CPQ gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/7285 NCBI SNPs in CPQ are shown (see all 7285)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2016533481,2
    		--97655513(+) AGAAT-/AAATAATT 1 -- us2k10--------
    rs350788711,2
    		C,--97655514(+) GAATA-/AATAATTA 1 -- us2k11Minor allele frequency- AAT:0.00NA 2
    rs763104631,2
    		--97655515(+) AATAAA/TTAATT 1 -- us2k10--------
    rs779331791,2
    		--97655516(+) ATAAAA/TAATTA 1 -- us2k10--------
    rs1858988841,2
    		--97655529(+) ACATAA/TCATGA 1 -- us2k10--------
    rs1897217631,2
    		--97655601(+) TGTGAA/GCAGAC 1 -- us2k10--------
    rs1834606501,2
    		--97655639(+) CCTAGC/TGTGGG 1 -- us2k10--------
    rs100868821,2
    		C,F,A,H,--97655880(+) GGGGGG/AAAATA 1 -- us2k127Minor allele frequency- A:0.37NS EA NA WA CSA 2768
    rs1421389741,2
    		--97655895(+) TGATAA/GTAATA 1 -- us2k10--------
    rs736962061,2
    		C,--97655948(+) AAAATC/ATTAGC 1 -- us2k11Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for CPQ (97657455 - 97907455 bp, first 250kb of CPQ)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CPQ: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPQ
    DNA2.0 Custom Variant and Variant Library Synthesis for CPQ

    Disorders / Diseases
    for CPQ gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CPQ for disorders           About GeneDecksing

    20/57 diseases for CPQ (see all 57):    About MalaCards
    non-hodgkin lymphoma    type 2 diabetes mellitus    granulocytopenia    myocardial infarction
    acute myocardial infarction    acute promyelocytic leukemia    hodgkin's lymphoma    diabetes mellitus
    interstitial lung disease    rheumatoid arthritis    pulmonary sarcoidosis    leukemia/lymphoma
    cholestasis    sarcoidosis    fibrosarcoma    liver disease
    renal cell carcinoma    choriocarcinoma    myelodysplastic syndrome    alzheimer's disease

    10/39 Novoseek disease relationships for CPQ gene (see all 39)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nasal epithelium 36.3 2 11955816 (1), 19405998 (1)
    choriocarcinoma 32.4 4 14691298 (1), 16364975 (1), 7961121 (1), 8572606 (1)
    alzheimers disease 6.23 10 2230828 (2), 9070837 (1), 9266855 (1), 11295540 (1) (see all 5)
    necrosis 4.14 1 12819930 (1)
    pneumonia 3.28 1 15751279 (1)
    cholestasis 2.85 1 8103033 (1)
    cardiovascular diseases 2.85 1 18373194 (1)
    leukemia promyelocytic acute 2.35 1 16800923 (1)
    carcinoma renal cell 1.53 3 1698011 (2), 17692401 (1)
    breast cancer 1.52 3 16619500 (1), 10508127 (1)


    Export disorders for CPQ gene to outside databases

    Publications
    for CPQ gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CPQ gene, integrated from 9 sources (see all 475):
    (articles sorted by number of sources associating them with CPQ)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification, cDNA cloning, and expression of a new human blood plasma glutamate carboxypeptidase homologous to N-acetyl-aspartyl- alpha-glutamate carboxypeptidase/prostate-specific membrane antigen. (PubMed id 10206990)1, 2, 3 Gingras R....Pshezhetsky A.V. (1999)
    2. Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma. (PubMed id 12591738)1, 2, 9 Smith M.W.... Katze M.G. (2003)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    4. Purification and primary structure determination of h uman lysosomal dipeptidase. (PubMed id 12675526)1, 2 Dolenc I. and Mihelic M. (2003)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. Human Variation in Alcohol Response Is Influenced by Variation in Neuronal Signaling Genes. (PubMed id 20201926)1 Joslyn G....White R.L. (2010)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. (PubMed id 20802479)1 Anttila V....Palotie A. (2010)
    9. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
    10. Presence of the propeptide on recombinant lysosomal dipeptidase controls both activation and dimerization. (PubMed id 17214548)2 Dolenc I.... Turk V. (2007)

    External Searches for CPQ gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CPQ gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10404 HGNC: 16910 AceView: PGCP Ensembl:ENSG00000104324 euGenes: HUgn10404
    ECgene: CPQ H-InvDB: CPQ

    Other Databases showing CPQ gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CPQ gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for CPQ gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CPQ gene:
    Search GeneIP for patents involving CPQ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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