Aliases for CPOX Gene
External Ids for CPOX Gene
Previous Symbols for CPOX Gene
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]
GeneCards Summary for CPOX Gene
CPOX (Coproporphyrinogen Oxidase) is a Protein Coding gene. Diseases associated with CPOX include coproporphyria and prostate disease. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include protein homodimerization activity and coproporphyrinogen oxidase activity.
UniProtKB/Swiss-Prot for CPOX Gene
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX