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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CPNE8 Gene

protein-coding   GIFtS: 49
GCID: GC12M039045

copine VIII
 Explore 4 diseases affiliated with
CPNE8 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CPNE8    

Aliases
for CPNE8 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Copine VIII1 2 3
Copine-81

External Ids:    HGNC: 234981   Entrez Gene: 1444022   Ensembl: ENSG000001391177   UniProtKB: Q86YQ83   

Export aliases for CPNE8 gene to outside databases

Previous GC identifers: GC12M037332 GC12M036072


Summaries
for CPNE8 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CPNE8:
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and
cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II
C2 domains and an integrin A domain-like sequence in the C-terminus. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CPNE8_HUMAN, Q86YQ8
Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties (By
similarity)

Gene Wiki entry for CPNE8


Genomic Views
for CPNE8 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CPNE8 gene promoter:
         ER-alpha   Bach1   GATA-3   Bach2   ATF-2   FOXO3   E4BP4   FOXO3b   HOXA5   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CPNE8 promoter sequence
   Search SABiosciences Chromatin IP Primers for CPNE8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPNE8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12   Ensembl cytogenetic band:  12q12   HGNC cytogenetic band: 12q12

CPNE8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPNE8 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M039045:  view genomic region     (about GC identifiers)

Start:
 39,040,624 bp from pter      End:
 39,301,232 bp from pter
Size:
 260,609 bases      Orientation:
 minus strand

Proteins
for CPNE8 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CPNE8_HUMAN, Q86YQ8 (See protein sequence)
Recommended Name: Copine-8  
Size: 564 amino acids; 63108 Da
Secondary accessions: Q2TB41

Explore the universe of human proteins at neXtProt for CPNE8: NX_Q86YQ8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q86YQ8

    • CPNE8 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_705898.1  
    ENSEMBL proteins: 
     ENSP00000329748   ENSP00000439237   ENSP00000353633   ENSP00000447761  

    Human Recombinant Protein Products: 
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    OriGene Purified Protein: CPNE8
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CPNE8


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    Novus Biologicals CPNE8 Antibodies
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    Uscn Antibodies for CPNE8
    ThermoFisher Antibodies for CPNE8

    Assay Products for CPNE8: 
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    Uscn ELISAs and CLIAs for CPNE8

    Protein Domains /
    Families
    for CPNE8 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CPNE8 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR018029 C2_membr_targeting
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR010734 Copine
     IPR000008 C2_Ca-dep
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry Q86YQ8

    ProtoNet protein and cluster: Q86YQ8

    3 Blocks protein families:
    IPB000008 C2 domain
    IPB002035 Von Willebrand factor type A domain signature
    IPB010734 Copine


    UniProtKB/Swiss-Prot: CPNE8_HUMAN, Q86YQ8
    Similarity: Belongs to the copine family
    Similarity: Contains 2 C2 domains
    Similarity: Contains 1 VWFA domain


    Function
    for CPNE8 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CPNE8_HUMAN, Q86YQ8
    Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties (By
    similarity)

    miRNA
    Products:            		miRTarBase miRNAs that target CPNE8:
    hsa-mir-30a (MIRT005134)

    OriGene 3'-UTR Clone: CPNE8
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPNE8
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate CPNE8 (see all 61):
    hsa-miR-188-5p hsa-miR-4328 hsa-miR-4305 hsa-miR-25 hsa-miR-3653 hsa-miR-30d hsa-miR-218 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmid: CPNE8 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE8 (see all 6)
    OriGene shRNA RFP: CPNE8
    OriGene siRNA: CPNE8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE8

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CPNE8

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE8 (see all 5)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE8
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CPNE8 (NM_153634)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPNE8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE8 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CPNE8
    Search LifeMap BioReagents cell lines for CPNE8

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE8


    Pathways & Interactions
    for CPNE8 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPNE8

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for CPNE8 (Q86YQ83 ENSP000003297484) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APLP2Q064813I2D: score=1 
    ARRB1P494073I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Drugs & Compounds
    for CPNE8 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CPNE8

    1 HMDB Compound for CPNE8    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about CPNE8 

    Transcripts
    for CPNE8 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CPNE8 gene: 
    NM_153634.2  

    Unigene Cluster for CPNE8:

    Copine VIII
    Hs.40910  [show with all ESTs]
    Unigene Representative Sequence: BX538055
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000552259 ENST00000331366(uc001rls.1) ENST00000538596(uc001rlr.1)
    ENST00000546603 ENST00000360449 ENST00000547417 ENST00000549842 ENST00000551855
    ENST00000550863

    miRNA
    Products:             		 OriGene 3'-UTR Clone: CPNE8
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPNE8
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate CPNE8 (see all 61):
    hsa-miR-188-5p hsa-miR-4328 hsa-miR-4305 hsa-miR-25 hsa-miR-3653 hsa-miR-30d hsa-miR-218 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmid: CPNE8 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE8 (see all 6)
    OriGene shRNA RFP: CPNE8
    OriGene siRNA: CPNE8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE8
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE8 (see all 5)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE8
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CPNE8 (NM_153634)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPNE8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE8 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPNE8
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CPNE8
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPNE8

    Additional cDNA sequence: 

    AK074223.1 AK094998.1 AK098593.1 AK307908.1 AY177785.1 BC046366.1 BC048260.1 BC068040.1 
    BC110577.1 BC110578.1 BX538055.1 

    10 DOTS entries:

    DT.100690399  DT.442159  DT.100033997  DT.40188510  DT.91661483  DT.92416947  DT.75146061  DT.95110919 
    DT.97808340  DT.91718466 

    24/63 AceView cDNA sequences (see all 63):

    BG034542 AW470493 BM672075 BC048260 BC046366 AI188010 AI014430 BX111100 
    AA976153 AK098593 CA419647 CR610762 BM720158 NM_153634 AW014148 BE646019 
    BX091603 BC068040 AA431782 AK094998 AK074223 BF476090 BP370374 AW293893 

    GeneLoc Exon Structure


    Expression
    for CPNE8 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CPNE8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CPNE8 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneZeugopod Epiphyseal EndChondrocytesBone, Cartilage
    BoneMaxillary ProcessBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ progenitor T42 (Embryonic Progenitor Cell)
    PureStem™ progenitor Z1 (Embryonic Progenitor Cell)
    Nkx2-1 GFP+ cells (Efficient derivation...)

    See CPNE8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CPNE8

    SOURCE GeneReport for Unigene cluster: Hs.40910
        SABiosciences Custom PCR Arrays for CPNE8
    Primer
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE8
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPNE8
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE8

    Orthologs
    for CPNE8 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CPNE8 gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CPNE81 copine VIII 83.15(n)
    92.32(a)    		   417690  NM_001199460.1  NP_001186389.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CPNE86
    		 --
    		 90(a)
    		 1 ↔ 1
    		 5(99049947-99101572)
    zebrafish
    (Danio rerio)    		 Actinopterygii cpne81 copine VIII 72.24(n)
    81.65(a)    		   100332028  XM_002666955.1  XP_002667001.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea cpna-16
    gem-46
    (see all 7)    		 Gon-2 Extragenic Modifier family member (gem-4)
    (see all 7)    		 7(a)
    39(a)
    (see all 7)    		 possible ortholog
    possible ortholog
    (see all 7)    		 II(4186669-4208502)
    IV(11745617-11748662)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G619101 DCD (Development and Cell Death) domain-containing more 51.31(n)
    46.08(a)    		   836312  NM_001203661.1  NP_001190590.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g05213001 hypothetical protein 50.36(n)
    41.26(a)    		   4329499  NM_001053511.1  NP_001046976.1 


    ENSEMBL Gene Tree for CPNE8 (if available)
    TreeFam Gene Tree for CPNE8 (if available) 

    Paralogs
    for CPNE8 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CPNE8 gene
    CPNE92  CPNE22  CPNE62  CPNE32  CPNE52  CPNE42  CPNE72  CPNE12  
    8 SIMAP similar genes for CPNE8 using alignment to 4 protein entries:     CPNE8_HUMAN (see all proteins):
    CPNE9    CPNE5    CPNE4    CPNE2    CPNE1    CPNE3
    CPNE6    CPNE7

    CPNE8 for paralogs           About GeneDecksing



    Genomic Variants
    for CPNE8 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4534 NCBI SNPs in CPNE8 are shown (see all 4534)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1397499371,2
    		--39045608(+) CTTTAC/TGAAGC 1 -- ds50010--------
    rs752314191,2
    		F,--39045702(+) GAGCTC/GTTCTC 1 -- ds50011Minor allele frequency- G:0.07WA 118
    rs125805031,2
    		C,F,H--39045720(+) ATAGTC/GTTGGA 1 -- ds50015Minor allele frequency- G:0.00NS EA NA 422
    rs171255661,2
    		C,--39045801(+) CTAATC/GTTACA 1 -- ds50014Minor allele frequency- G:0.04NA WA 260
    rs171255701,2
    		C,F,H,--39045924(+) CAATCT/CATTAT 1 -- ds50018Minor allele frequency- C:0.01NA NS CSA 554
    rs1444424301,2
    		--39045969(+) GGACAC/GTTCAA 1 -- ds50010--------
    rs111689851,2
    		C,F,H,--39045983(+) AATAAC/ATGATG 1 -- ds500125Minor allele frequency- A:0.18NA NS EA 2552
    rs79702731,2
    		C,F,A,H,--39046064(+) AAATCC/TGTAGG 1 -- ut31 ese39Minor allele frequency- T:0.45NA EA 392
    rs1930809931,2
    		--39046065(+) AATCTA/GTAGGT 1 -- ut310--------
    rs1143612311,2
    		F,--39046092(+) ATAAAT/CATTTA 1 -- ut311Minor allele frequency- C:0.02WA 118

    HapMap Linkage Disequilibrium report for CPNE8 (39040624 - 39290624 bp, first 250kb of CPNE8)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for CPNE8
         1 CNV: 5309
         1 Indel: 11608

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPNE8
    DNA2.0 Custom Variant and Variant Library Synthesis for CPNE8

    Disorders / Diseases
    for CPNE8 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CPNE8 for disorders           About GeneDecksing

    4 diseases for CPNE8:    About MalaCards
    prion disease    hermaphroditism    infertility    leukemia

    1 disease from the University of Copenhagen DISEASES database for CPNE8:
    Distal arthrogryposis

    Export disorders for CPNE8 gene to outside databases

    Publications
    for CPNE8 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CPNE8 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with CPNE8)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Cloning, molecular characterization, and expression analysis of copine 8. (PubMed id 12670487)1, 3 Maitra R.... Lee B. (2003)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PubMed id 17620599)1 Xiao K....Lefkowitz R.J. (2007)

    External Searches for CPNE8 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CPNE8 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 144402 HGNC: 23498 AceView: CPNE8 Ensembl:ENSG00000139117 euGenes: HUgn144402
    ECgene: CPNE8 H-InvDB: CPNE8

    Other Databases showing CPNE8 gene

    (According to HUGE)
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    Specialized Databases showing CPNE8 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CPNE8 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CPNE8 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for CPNE8 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CPNE8 gene:
    Search GeneIP for patents involving CPNE8

    GeneCards and IP:
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