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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CPNE5 Gene

protein-coding GIFtS: 50
GCID: GC06M036755

copine V

Explore 2 diseases affiliated with
CPNE5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Copine V¹ ² ³
CPN5¹ ² ⁵
COPN5¹ ²
KIAA1599¹ ³
Copine-5¹

External Ids:	HGNC: 2318¹	Entrez Gene: 57699²	Ensembl: ENSG00000124772⁷	OMIM: 604209⁵	UniProtKB: Q9HCH3³

Export aliases for CPNE5 gene to outside databases

Previous GC identifers: GC06M036710 GC06M036816 GC06M036426

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CPNE5:

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and

cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II

C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple

alternatively spliced transcript variants but their full-length natures could not be determined. (provided by RefSeq,

Jul 2008)

UniProtKB/Swiss-Prot: CPNE5_HUMAN, Q9HCH3

Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CPNE5 gene promoter:
NF-1 AML1a HTF GATA-1 E47 MEF-2A c-Rel FOXJ2 (long isoform) FOXJ2 aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CPNE5 promoter sequence

Search SABiosciences Chromatin IP Primers for CPNE5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPNE5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.2 HGNC cytogenetic band: 6p21.2

CPNE5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPNE5 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M036755: view genomic region (about GC identifiers)

Start:	36,708,552 bp from pter	End:	36,807,778 bp from pter
Size:	99,227 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CPNE5_HUMAN, Q9HCH3 (See protein sequence)

Recommended Name: Copine-5

Size: 593 amino acids; 65734 Da

Sequence caution: Sequence=BAB13425.1; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for CPNE5: NX_Q9HCH3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HCH3

CPNE5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065990.1

ENSEMBL proteins:

ENSP00000244751 ENSP00000376885

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals CPNE5 Proteins Novus Biologicals CPNE5 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CPNE5

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0043005	neuron projection	IEA	--
GO:0043025	neuronal cell body	IEA	--

CPNE5 for ontologies About GeneDecksing

CPNE5 Antibody Products:

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	Novus Biologicals CPNE5 Antibodies
	Search for Antibodies for CPNE5 at Abcam
	Uscn Antibodies for CPNE5
	Search ThermoFisher Antibodies for CPNE5

Assay Products for CPNE5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CPNE5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CPNE5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CPNE5 for domains About GeneDecksing

5 InterPro domains/families:

IPR018029 C2_membr_targeting

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR010734 Copine

IPR000008 C2_Ca-dep

IPR002035 VWF_A

Graphical View of Domain Structure for InterPro Entry Q9HCH3

ProtoNet protein and cluster: Q9HCH3

3 Blocks protein families:

IPB000008 C2 domain

IPB002035 Von Willebrand factor type A domain signature

IPB010734 Copine

UniProtKB/Swiss-Prot: CPNE5_HUMAN, Q9HCH3

Similarity: Belongs to the copine family

Similarity: Contains 2 C2 domains

Similarity: Contains 1 VWFA domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CPNE5_HUMAN, Q9HCH3

Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties (By

copine 5,calcium-dependent,phospholipid binding protein,potentially involved in regulating membrane

trafficking,expressed in several tissues

miRNA Products:		OriGene 3'-UTR Clone: CPNE5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPNE5
		8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate CPNE5 (see all 14):
		hsa-miR-194* hsa-miR-3910 hsa-miR-4328 hsa-miR-548b-3p hsa-miR-486-3p hsa-miR-3133 hsa-miR-3692 hsa-miR-23b*

		SwitchGear 3'UTR luciferase reporter plasmid: CPNE5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE5 (see all 7) OriGene shRNA RFP: CPNE5 OriGene siRNA: CPNE5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE5

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CPNE5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CPNE5 (NM_020939)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CPNE5
		Search LifeMap BioReagents cell lines for CPNE5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE5

2 GenomeRNAi human phenotypes for CPNE5:

Increased G2M DNA content

Synthetic lethal with Ras

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CPNE5

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CPNE5 (ENSP00000244751⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CPNE5

1 HMDB Compound for CPNE5 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about CPNE5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CPNE5 gene:

NM_020939.1

Unigene Cluster for CPNE5:

Copine V

Hs.657869 [show with all ESTs]

Unigene Representative Sequence: AB046819

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000459703 ENST00000244751(uc003omr.1 uc003oms.1) ENST00000493411

ENST00000393189(uc003omp.1 uc010jwn.1 uc003omq.1)

miRNA Products:		OriGene 3'-UTR Clone: CPNE5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPNE5
		8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate CPNE5 (see all 14):
		hsa-miR-194* hsa-miR-3910 hsa-miR-4328 hsa-miR-548b-3p hsa-miR-486-3p hsa-miR-3133 hsa-miR-3692 hsa-miR-23b*

		SwitchGear 3'UTR luciferase reporter plasmid: CPNE5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE5 (see all 7) OriGene shRNA RFP: CPNE5 OriGene siRNA: CPNE5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPNE5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CPNE5 (NM_020939)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPNE5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPNE5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat CPNE5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPNE5

Additional cDNA sequence:

AB046819.1 BC012765.2 BC036840.1 BC053872.1

14 DOTS entries:

DT.209642 DT.99976680 DT.101983136 DT.40277499 DT.95161624 DT.99933253 DT.91950731 DT.121369636

DT.40126474 DT.100745079 DT.95358542 DT.97848838 DT.406173 DT.95208386

24/156 AceView cDNA sequences (see all 156):

CB852499 BQ054778 BQ054669 BC012765 AA262275 BQ065230 BX102637 BX118391

AW268855 BQ054550 BQ065446 CB852991 NM_020939 AW268865 BC036840 BM927433

BQ066288 BQ065904 AA731433 BQ063859 AI382977 AA465140 BQ027323 BM703923

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CPNE5 (see all 8) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20a	·	20b	^	21	^	22	^
SP1:					-														-		-										-										-
SP2:					-														-
SP3:					-
SP4:																																							-		-
SP5:																																							-		-

ExUns:	23a	·	23b	^	24	^	25
SP1:	-
SP2:
SP3:
SP4:	-
SP5:

ECgene alternative splicing isoforms for CPNE5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CPNE5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

CPNE5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Left Ventricle

Heart

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CPNE5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CPNE5

SOURCE GeneReport for Unigene cluster: Hs.657869

SABiosciences Custom PCR Arrays for CPNE5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPNE5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat CPNE5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPNE5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for CPNE5 gene from 6/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	CPNE5⁶	--	82(a)	1 ↔ 1	4(105280620-105377562)
African clawed frog (Xenopus laevis)	Amphibia	Xl.32366²	Xenopus laevis transcribed sequence with moderate similarity more	74.9(n)		BJ632009.1
zebrafish (Danio rerio)	Actinopterygii	zgc64194²	similar to copine V	79.58(n)		394003 BC054636.1
worm (Caenorhabditis elegans)	Secernentea	nra-1¹	Protein NRA-1	50.97(n) 48.97(a)		178508 NM_182304.2 NP_872104.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G63970⁶ RGLG2⁶ (see all 5)	E3 ubiquitin-protein ligase RGLG2 (see all 5)	20(a) 18(a) (see all 5)	possible ortholog possible ortholog (see all 5)	5(25606771-25609247) 5(4648111-4651309)
rice (Oryza sativa)	Liliopsida	-- -- (see all 7)	copine, putative, expressed (see all 7)	8(a) 20(a) (see all 7)	possible ortholog possible ortholog (see all 7)	9(22507403-22512808) 1(42349883-42354354)

ENSEMBL Gene Tree for CPNE5 (if available)
TreeFam Gene Tree for CPNE5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CPNE5 gene

CPNE9² CPNE2² CPNE6² CPNE3² CPNE8² CPNE4² CPNE7² CPNE1²

9 SIMAP similar genes for CPNE5 using alignment to 2 protein entries: CPNE5_HUMAN (see all proteins):

DKFZp666C234 CPNE9 CPNE8 CPNE4 CPNE1 CPNE3

CPNE2 CPNE6 CPNE7

CPNE5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76974772^1,2	C,F,	--	36708063(+)	`GGCCTC/TGCTCT`	1	--	ds500¹		1		NA	120
rs73412301^1,2	C,	--	36708110(+)	`CTTTGC/TGCCTG`	1	--	ds500¹		1		WA	2
rs6909821^1,2	C,F,H,	--	36708164(+)	`GCTCCC/TTGTCT`	1	--	ds500¹		10		NS EA CSA WA	1212
rs2395662^1,2	C,F,A,H,	--	36708196(+)	`AACCAC/TGACCT`	1	--	ds500¹		13		NS EA NA WA CSA	788
rs145652239^1,2		--	36708245(+)	`TCACCC/TTCCTT`	1	--	ds500¹		0	--	--	--	--
rs148898607^1,2		--	36708423(+)	`CAGAGC/TGTGGC`	1	--	ds500¹		0	--	--	--	--
rs77952936^1,2		--	36708430(+)	`TGGCAC/TGTGGC`	1	--	ds500¹		1		EA	120
rs6933110^1,2	C,F,H,	--	36708467(+)	`AACAAT/CTGAAG`	1	--	ds500¹		6		NS EA CSA	424
rs45596537^1,2		--	36708512(+)	`GCAACA/GTCAGT`	1	--	ds500¹		0	--	--	--	--
rs140957358^1,2		--	36708547(+)	`AACTTC/GGTGCT`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CPNE5 (36708552 - 36807778 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CPNE5
2 CNVs: 10149 59337

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPNE5

DNA2.0 Custom Variant and Variant Library Synthesis for CPNE5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CPNE5 for disorders           About GeneDecksing

OMIM gene information: 604209    OMIM disorders: --

2 diseases for CPNE5:    About MalaCards

hermaphroditism infertility

Human Genome Epidemiology (HuGE) Navigator: CPNE5 (1 document)

Export disorders for CPNE5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CPNE5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CPNE5)

Utopia: connect your pdf to the dynamic
world of online information

The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)^{1, 2} Nagase T.... Ohara O. (2000)
The copines, a novel class of C2 domain-containing, calcium- dependent, phospholipid-binding proteins conserved from Paramecium to humans. (PubMed id 9430674)^{1, 3} Creutz C.E.... Cohen J. (1998)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex. (PubMed id 9647638)¹ Tripodis N....Ragoussis J. (1998)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57699	HGNC: 2318	AceView: CPNE5	Ensembl:ENSG00000124772	euGenes: HUgn57699
ECgene: CPNE5	H-InvDB: CPNE5

(According to HUGE)
About This Section

HUGE: KIAA1599

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CPNE5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CPNE5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CPNE5 gene:
Search GeneIP for patents involving CPNE5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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	Browse OriGene Antibodies		OriGene shRNA RFP for CPNE5
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE5		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPNE5
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CPNE5
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPNE5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPNE5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE5
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE5

	GenScript Custom Purified and Recombinant Proteins Services for CPNE5		GenScript cDNA clones with any tag delivered in your preferred vector for CPNE5
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	Regulatory tfbs in CPNE5 promoter
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE5

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Search ThermoFisher Antibodies for CPNE5

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE5

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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CPNE5 Gene

copine V

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Expression
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