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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CPN2 Gene

protein-coding   GIFtS: 51
GCID: GC03M194060

Carboxypeptidase N, Polypeptide 2

(Previous names: carboxypeptidase N, polypeptide 2, 83kD)
(Previous symbol: ACBP)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Carboxypeptidase N, Polypeptide 21 2     Carboxypeptidase N Regulatory Subunit2 3
ACBP1 2 3     Arginine Carboxypeptidase (Carboxypeptidase N)2
Carboxypeptidase N, Polypeptide 2, 83kD1 2     Carboxypeptidase N Subunit 22
Carboxypeptidase N 83 KDa Chain2 3     Carboxypeptidase N Polypeptide 23
Carboxypeptidase N Large Subunit2 3     

External Ids:    HGNC: 23131   Entrez Gene: 13702   Ensembl: ENSG000001787727   OMIM: 6031045   UniProtKB: P227923   

Export aliases for CPN2 gene to outside databases

Previous GC identifers: GC08U990012 GC03M195380 GC03M195542 GC03U900610 GC03M191440


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CPN2 Gene: 
CPN2 (carboxypeptidase N, polypeptide 2) is a protein-coding gene. Diseases associated with CPN2 include corticosterone methyloxidase type ii deficiency, and corticosterone methyloxidase type i deficiency. GO annotations related to this gene include enzyme regulator activity. An important paralog of this gene is NYX.

UniProtKB/Swiss-Prot: CPN2_HUMAN, P22792
Function: The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in
circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit

Gene Wiki entry for CPN2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_029928.13  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CPN2 gene promoter:
         GR   PPAR-gamma1   GR-beta   Hand1   PPAR-gamma2   GR-alpha   NF-kappaB1   E47   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CPN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q29   Ensembl cytogenetic band:  3q29   HGNC cytogenetic band: 3q29

CPN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPN2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M194060:  view genomic region     (about GC identifiers)

Start:
194,060,494 bp from pter      End:
194,072,057 bp from pter
Size:
11,564 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CPN2_HUMAN, P22792 (See protein sequence)
Recommended Name: Carboxypeptidase N subunit 2 precursor  
Size: 545 amino acids; 60557 Da
Subunit: Tetramer of two catalytic chains and two glycosylated inactive chains
Subcellular location: Secreted
Secondary accessions: B2RPE7 Q86SU4 Q8N5V4

Explore the universe of human proteins at neXtProt for CPN2: NX_P22792

Explore proteomics data for CPN2 at MOPED 

Post-translational modifications:

  • UniProtKB: Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain
    disulfide bonds with the 50 kDa catalytic subunit
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P22792

  • CPN2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CPN2 Protein Expression
    REFSEQ proteins: NP_001073982.2  
    ENSEMBL proteins: 
     ENSP00000319464   ENSP00000402232  

    Human Recombinant Protein Products for CPN2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for CPN2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for CPN2
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CPN2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS2378615

    CPN2 for ontologies           About GeneDecksing



    CPN2 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for CPN2 

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    Cloud-Clone Corp. ELISAs for CPN2 
    Cloud-Clone Corp. CLIAs for CPN2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: Carboxypeptidase N, polypeptide 2 
    Metallocarboxypeptidases

    5 InterPro protein domains:
     IPR000483 Cys-rich_flank_reg_C
     IPR001611 Leu-rich_rpt
     IPR025875 Leu-rich_rpt_4
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry P22792

    ProtoNet protein and cluster: P22792

    2 Blocks protein domains:
    IPB000372 Cysteine-rich flanking region
    IPB000483 Cysteine-rich flanking region


    UniProtKB/Swiss-Prot: CPN2_HUMAN, P22792
    Similarity: Contains 12 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 LRRNT domain


    CPN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CPN2_HUMAN, P22792
    Function: The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in
    circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit

         Genatlas biochemistry entry for CPN2:
    carboxypeptidase N2 regulatory subunit,83kDa

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0030234enzyme regulator activity NAS2378615
         
    CPN2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Cpn2 (no phenotypes)

    CPN2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cpn2tm1Lex for CPN2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CPN2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CPN2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CPN2 
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    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate CPN2:
    hsa-miR-515-5p hsa-miR-766 hsa-miR-450b-5p hsa-miR-519e*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of CPN2 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPN2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPN2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CPN2 (ENSP000003194644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CPN1ENSP000003594464STRING: ENSP00000359446
    IKBKGENSP000003586224STRING: ENSP00000358622
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050790regulation of catalytic activity NAS2378615
    GO:0050821protein stabilization NAS2378615

    CPN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CPN2

    1 HMDB Compound for CPN2    About this table
    CompoundSynonyms CAS #PubMed Ids
    ZincZinc (see all 2)7440-66-6--

    Search CenterWatch for drugs/clinical trials and news about CPN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CPN2 gene: 
    NM_001080513.2  

    Unigene Cluster for CPN2:

    Carboxypeptidase N, polypeptide 2
    Hs.528368  [show with all ESTs]
    Unigene Representative Sequence: NM_001080513
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000323830(uc003fts.3) ENST00000429275
    miRNA
    Products:
         
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate CPN2:
    hsa-miR-515-5p hsa-miR-766 hsa-miR-450b-5p hsa-miR-519e*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CPN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPN2
    Clone
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    GenScript: all cDNA clones in your preferred vector: CPN2 (NM_001080513)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPN2
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPN2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPN2

    Additional mRNA sequence: 

    BC031569.1 BC042334.1 BC137398.1 BC137403.1 J05158.2 

    1 DOTS entry:

    DT.412177 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CPN2 expression in normal human tissues (normalized intensities)      CPN2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCACTCATA
    CPN2 Expression
    About this image


    CPN2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Adipose (Muscoskeletal System)
             Interscapular Brown Adipose Depot
     
     Eye (Sensory Organs)
             retinal amacrine cell p0   
     
     Liver (Hepatobiliary System)

    See CPN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CPN2

    SOURCE GeneReport for Unigene cluster: Hs.528368
        SABiosciences Custom PCR Arrays for CPN2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CPN2 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cpn21 , 5 carboxypeptidase N, polypeptide 21, 5 75.96(n)1
    67.71(a)1
      16 (21.22 cM)5
    717561  NM_027904.31  NP_082180.21 
     302563785 
    chicken
    (Gallus gallus)
    Aves CPN21 carboxypeptidase N, polypeptide 2 57.82(n)
    44.31(a)
      424899  XM_422710.3  XP_422710.3 
    lizard
    (Anolis carolinensis)
    Reptilia CPN26
    carboxypeptidase N, polypeptide 2
    43(a)
    1 ↔ 1
    GL343538.1(375683-380205)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1539131 zgc:153913 49.5(n)
    34.55(a)
      559700  NM_001079979.1  NP_001073448.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78966
    Toll-76
    (see all 7)
    Toll-7
    (see all 7)
    9(a)
    9(a)
    (see all 7)
    possible ortholog
    many ↔ many
    (see all 7)
    3R(25809174-25816514)
    2R(15714410-15720473)
    worm
    (Caenorhabditis elegans)
    Secernentea lron-111 Protein LRON-11 45.26(n)
    31.69(a)
      171837  NM_058634.3  NP_491035.1 


    ENSEMBL Gene Tree for CPN2 (if available)
    TreeFam Gene Tree for CPN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CPN2 gene
    NYX2  GP52  LRIG32  LRRTM42  LRRC152  CHAD2  LRIG22  LRRTM32  
    IGFALS2  CHADL2  LRIG12  LRRTM22  RTN4R2  LRRC702  RTN4RL12  LRRTM12  
    RTN4RL22  LRG12  
    5 SIMAP similar genes for CPN2 using alignment to 1 protein entry:     CPN2_HUMAN:
    ISLR    LGR6    LRIG3    HMFT1766    LRG1

    CPN2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CPN2
    PGOHUM00000232632


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/528 SNPs in CPN2 are shown (see all 528)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0651864
    ----see VAR_0651862 Q R mis40--------
    rs68062821,2
    C,F,A,H--194060008(+) GTCGCC/TTGGGG 1 -- int125Minor allele frequency- T:0.39EA NS NA WA CSA 2268
    rs748549071,2
    C,F--194060050(+) AAAACG/ACCGCT 1 -- int11Minor allele frequency- A:0.06WA 118
    rs1412683371,2
    --194060053(+) ACGCCA/GGTGCC 1 -- int10--------
    rs67723001,2
    C,F,H--194060054(+) CGCCGG/CTGCCT 1 -- int120Minor allele frequency- C:0.13EA NS NA WA CSA 1091
    rs1907576121,2
    --194060066(+) GGCCCC/TGTTTT 1 -- int10--------
    rs785655751,2
    C--194060080(+) AGATCC/TTGATT 1 -- int14Minor allele frequency- T:0.13CSA WA NA EA 359
    rs1436873001,2
    C--194060106(+) TGGTGG/TTGTGA 1 -- int10--------
    rs1808573101,2
    --194060161(+) TCTCAC/TGCGGG 1 -- int10--------
    rs1123010851,2
    C,F--194060162(+) CTCACG/ACGGGA 1 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for CPN2 (194060494 - 194072057 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CPN2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2726431CNV Deletion23290073
    esv2563733CNV Insertion19546169
    esv24336CNV Gain19812545

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CPN2
    DNA2.0 Custom Variant and Variant Library Synthesis for CPN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603104    OMIM disorders: --

    3 diseases for CPN2:    About MalaCards
    corticosterone methyloxidase type ii deficiency    corticosterone methyloxidase type i deficiency    glucocorticoid-remediable aldosteronism


    CPN2 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: CPN2 (185 documents)

    Export disorders for CPN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CPN2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with CPN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The deduced protein sequence of the human carboxypeptidase N high molecular weight subunit reveals the presence of leucine-rich tandem repeats. (PubMed id 2378615)1, 2, 3 Tan F.... Erdoes E.G. (1990)
    2. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. (PubMed id 14760718)1, 2 Bunkenborg J.... Wisniewski J.R. (2004)
    5. Chromosomal localization of the genes for human carboxypeptidase D (CPD) and the active 50-kilodalton subunit of human carboxypeptidase N (CPN1). (PubMed id 9628828)1, 3 Riley D.A....Skidgel R.A. (1998)
    6. Amino acid sequence of the N-terminus and selected tryptic peptides of the active subunit of human plasma carboxypeptidase N: comparison with other carboxypeptidases. (PubMed id 3408501)1, 2 Skidgel R.A....Erdoes E.G. (1988)
    7. Identification of genetic factors associated with sus ceptibility to angiotensin-converting enzyme inhibitors-induced cough. (PubMed id 21052031)1 Grilo A....SA!ez M.E. (2011)
    8. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1370 HGNC: 2313 Ensembl:ENSG00000178772 euGenes: HUgn1370 ECgene: CPN2
    H-InvDB: CPN2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CPN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CPN2 gene:
    Search GeneIP for patents involving CPN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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