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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CPLX4 Gene

protein-coding   GIFtS: 43
GCID: GC18M056962

Complexin 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Complexin 41 2
Complexin IV2 3
CPX IV2 3
CPX-IV2
CPXIV2
complexin-42

External Ids:    HGNC: 243301   Entrez Gene: 3393022   Ensembl: ENSG000001665697   OMIM: 6095865   UniProtKB: Q7Z7G23   

Export aliases for CPLX4 gene to outside databases

Previous GC identifers: GC18M056748 GC18M055112 GC18M055111 GC18M055113 GC18M053671


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CPLX4 Gene:
This gene likely encodes a member of the complexin family. The encoded protein may be involved in synaptic vesicle
exocytosis. (provided by RefSeq, Jan 2009)

GeneCards Summary for CPLX4 Gene: 
CPLX4 (complexin 4) is a protein-coding gene. Diseases associated with CPLX4 include cocaine dependence, and retinitis, and among its related super-pathways are Synaptic Vesicle Pathway. GO annotations related to this gene include syntaxin binding. An important paralog of this gene is CPLX3.

UniProtKB/Swiss-Prot: CPLX4_HUMAN, Q7Z7G2
Function: Positively regulates a late step in synaptic vesicle exocytosis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.2  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CPLX4 gene promoter:
         Pbx1a   AML1a   MyoD   C/EBPalpha   HNF-1A   AREB6   Nkx6-1   FOXO4   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCPLX4 promoter sequence
   Search SABiosciences Chromatin IP Primers for CPLX4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPLX4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.32   Ensembl cytogenetic band:  18q21.32   HGNC cytogenetic band: 18q21.32

CPLX4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPLX4 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M056962:  view genomic region     (about GC identifiers)

Start:
56,942,388 bp from pter      End:
56,985,881 bp from pter
Size:
43,494 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CPLX4_HUMAN, Q7Z7G2 (See protein sequence)
Recommended Name: Complexin-4 precursor  
Size: 160 amino acids; 18336 Da
Subunit: Weakly binds to the SNARE core complex containing SNAP25, VAMP2 and STX1A (By similarity)
Subcellular location: Membrane; Lipid-anchor. Cell junction, synapse (By similarity). Note=Enriched at the
synaptic terminal (By similarity)

Explore the universe of human proteins at neXtProt for CPLX4: NX_Q7Z7G2

Explore proteomics data for CPLX4 at MOPED 

Post-translational modifications:

  • UniProtKB: Farnesylation mediates presynaptic targeting and is important for function in neurotransmitter release (By
    similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z7G2

  • CPLX4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CPLX4 Protein Expression
    REFSEQ proteins: NP_857637.1  
    ENSEMBL proteins: 
     ENSP00000466304   ENSP00000299721  

    Human Recombinant Protein Products for CPLX4: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CPLX4 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane IEA--
    GO:0030054cell junction IEA--
    GO:0045202synapse IEA--

    CPLX4 for ontologies           About GeneDecksing



    CPLX4 Antibody Products: 
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    Cloud-Clone Corp. Antibodies for CPLX4 
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    Assay Products for CPLX4: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for CPLX4 
    Cloud-Clone Corp. CLIAs for CPLX4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008849 Synaphin

    Graphical View of Domain Structure for InterPro Entry Q7Z7G2

    ProtoNet protein and cluster: Q7Z7G2

    UniProtKB/Swiss-Prot: CPLX4_HUMAN, Q7Z7G2
    Similarity: Belongs to the complexin/synaphin family


    CPLX4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CPLX4_HUMAN, Q7Z7G2
    Function: Positively regulates a late step in synaptic vesicle exocytosis (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000149SNARE binding ----
    GO:0019905syntaxin binding IEA--
         
    CPLX4 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cplx4):
     nervous system  vision/eye 

    CPLX4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cplx4tm1Bros for CPLX4

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CPLX4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CPLX4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CPLX4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CPLX4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPLX4
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate CPLX4:
    hsa-miR-221* hsa-miR-146a* hsa-miR-659 hsa-miR-4311 hsa-miR-3140-3p hsa-miR-544
    SwitchGear 3'UTR luciferase reporter plasmidCPLX4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CPLX4
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of CPLX4

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CPLX4 (see all 6)
    OriGene ORF clones in mouse, rat for CPLX4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CPLX4 (NM_181654)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPLX4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPLX4
    Sirion Biotech Customized lentivirus for stable overexpression of CPLX4 
                         Customized lentivirus expression plasmids for stable overexpression of CPLX4 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CPLX4
    Search LifeMap BioReagents cell lines for CPLX4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPLX4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CPLX4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Synaptic vesicle cycle
    Synaptic vesicle cycle0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for CPLX4):
        Synaptic vesicle cycle


    CPLX4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPLX4

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006836neurotransmitter transport IEA--
    GO:0006887exocytosis IEA--
    GO:0046928regulation of neurotransmitter secretion IEA--

    CPLX4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CPLX4

    Search CenterWatch for drugs/clinical trials and news about CPLX4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CPLX4 gene: 
    NM_181654.3  

    Unigene Cluster for CPLX4:

    Complexin 4
    Hs.449884  [show with all ESTs]
    Unigene Representative Sequence: NM_181654
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587244 ENST00000299721(uc002lhy.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CPLX4
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate CPLX4:
    hsa-miR-221* hsa-miR-146a* hsa-miR-659 hsa-miR-4311 hsa-miR-3140-3p hsa-miR-544
    SwitchGear 3'UTR luciferase reporter plasmidCPLX4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CPLX4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPLX4
    Clone
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    OriGene clones in human, mouse for CPLX4 (see all 6)
    OriGene ORF clones in mouse, rat for CPLX4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CPLX4 (NM_181654)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPLX4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPLX4
    Sirion Biotech Customized lentivirus for stable overexpression of CPLX4 
                         Customized lentivirus expression plasmids for stable overexpression of CPLX4 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CPLX4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CPLX4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPLX4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPLX4

    Additional mRNA sequence: 

    AB593158.1 AK123184.1 AY286502.1 BC065562.1 BC106886.2 BC106887.1 BC106888.1 BX640655.1 
    BX648518.1 

    2 DOTS entries:

    DT.40254711  DT.99938306 

    13 AceView cDNA sequences:

    AA365242 NM_181654 BC065562 AY286502 AK123184 BX510095 BM661846 BX640655 
    BX648518 BM661830 BU187675 BM689812 BG472915 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CPLX4 expression in normal human tissues (normalized intensities)      CPLX4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CPLX4 Expression
    About this image


    CPLX4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer

    See CPLX4 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.449884
        SABiosciences Custom PCR Arrays for CPLX4
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CPLX4
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPLX4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPLX4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPLX4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CPLX4 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cplx41 , 5 complexin 41, 5 87.29(n)1
    91.87(a)1
      18 (39.05 cM)5
    2256441  NM_145493.11  NP_663468.11 
     659557275 
    chicken
    (Gallus gallus)
    Aves CPLX41 complexin 4 80(n)
    87.5(a)
      769026  XM_001231726.1  XP_001231727.1 
    lizard
    (Anolis carolinensis)
    Reptilia CPLX46
    Uncharacterized protein
    86(a)
    1 ↔ 1
    GL343335.1(966991-1018086)
    African clawed frog
    (Xenopus laevis)
    Amphibia CD256876.12   -- 74.56(n)    CD256876.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cplx4a1 complexin 4a 68.76(n)
    74.21(a)
      768157  NM_001077300.1  NP_001070768.1 


    ENSEMBL Gene Tree for CPLX4 (if available)
    TreeFam Gene Tree for CPLX4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CPLX4 gene
    CPLX32  
    1 SIMAP similar gene for CPLX4 using alignment to 3 protein entries:     CPLX4_HUMAN (see all proteins):
    CPLX3

    CPLX4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/554 SNPs in CPLX4 are shown (see all 554)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1884245091,2
    --56962144(+) TGAGAA/CAACGA 1 -- ds50010--------
    rs349736251,2
    C,F--56962147(+) GACAAC/TGACCA 1 -- ds500111Minor allele frequency- T:0.13NA WA CSA 433
    rs1490991301,2
    --56962178(+) GGCAGA/TCAAGA 1 -- ds50010--------
    rs1431832811,2
    --56962188(+) AGGAAG/TTGCCA 1 -- ds50010--------
    rs1917830781,2
    --56962213(+) TTAGCA/TGAACT 1 -- ds50010--------
    rs1482829291,2
    --56962226(+) CTGCAC/TCTTTT 1 -- ds50010--------
    rs1840958021,2
    --56962256(+) TTGTCA/TTCCTG 1 -- ds50010--------
    rs764141271,2
    C,F--56962386(+) GCAGAG/ATCAGG 1 -- ds50011Minor allele frequency- A:0.24EA 120
    rs1411413321,2
    --56962406(+) GAAAAC/TAAATG 1 -- ds50010--------
    rs749314111,2
    C,F--56962488(+) ACATGC/TCATTT 1 -- ds50011Minor allele frequency- T:0.24EA 120

    HapMap Linkage Disequilibrium report for CPLX4 (56942388 - 56985881 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CPLX4: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CPLX4
    DNA2.0 Custom Variant and Variant Library Synthesis for CPLX4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609586    OMIM disorders: --

    2 diseases for CPLX4:    About MalaCards
    cocaine dependence    retinitis

    1 disease from the University of Copenhagen DISEASES database for CPLX4:
    Cocaine dependence

    CPLX4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CPLX4

    Export disorders for CPLX4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CPLX4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CPLX4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structurally and functionally unique complexins at retinal ribbon synapses. (PubMed id 15911881)1, 2, 3 Reim K.... Brose N. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (2011)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
    8. The carboxy-terminal domain of complexin I stimulates liposome fusion. (PubMed id 19179400)9 Malsam J....SAPllner T.H. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 339302 HGNC: 24330 AceView: CPLX4 Ensembl:ENSG00000166569 euGenes: HUgn339302
    ECgene: CPLX4 Kegg: 339302 H-InvDB: CPLX4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CPLX4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CPLX4 gene:
    Search GeneIP for patents involving CPLX4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Regulatory tfbs in CPLX4 promoter
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     Proteins for CPLX4
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPLX4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for CPLX4
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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