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Aliases for CPED1 Gene

Aliases for CPED1 Gene

  • Cadherin Like And PC-Esterase Domain Containing 1 2 3
  • Cadherin-Like And PC-Esterase Domain Containing 1 2 3 5
  • C7orf58 3 4
  • Chromosome 7 Open Reading Frame 58 2

External Ids for CPED1 Gene

Previous HGNC Symbols for CPED1 Gene

  • C7orf58

Previous GeneCards Identifiers for CPED1 Gene

  • GC07P120629

Summaries for CPED1 Gene

GeneCards Summary for CPED1 Gene

CPED1 (Cadherin Like And PC-Esterase Domain Containing 1) is a Protein Coding gene.

Gene Wiki entry for CPED1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CPED1 Gene

Genomics for CPED1 Gene

Regulatory Elements for CPED1 Gene

Enhancers for CPED1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CPED1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CPED1 Gene

120,988,677 bp from pter
121,297,444 bp from pter
308,768 bases
Plus strand

Genomic View for CPED1 Gene

Genes around CPED1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CPED1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CPED1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CPED1 Gene

Proteins for CPED1 Gene

  • Protein details for CPED1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cadherin-like and PC-esterase domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A8K1R3
    • Q6UXT1
    • Q86T76
    • Q86T84
    • Q8N2T5
    • Q96NC9

    Protein attributes for CPED1 Gene

    1026 amino acids
    Molecular mass:
    117491 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH30538.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CPED1 Gene


neXtProt entry for CPED1 Gene

Proteomics data for CPED1 Gene at MOPED

Post-translational modifications for CPED1 Gene

  • Glycosylation at Asn 251, Asn 404, Asn 413, Asn 737, Asn 791, and Asn 985
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CPED1 Gene

Domains & Families for CPED1 Gene

Protein Domains for CPED1 Gene

Suggested Antigen Peptide Sequences for CPED1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PC-esterase family.
  • Belongs to the PC-esterase family.
genes like me logo Genes that share domains with CPED1: view

No data available for Gene Families for CPED1 Gene

Function for CPED1 Gene

genes like me logo Genes that share phenotypes with CPED1: view

Animal Model Products

miRNA for CPED1 Gene

miRTarBase miRNAs that target CPED1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CPED1 Gene

Localization for CPED1 Gene

Subcellular locations from

Jensen Localization Image for CPED1 Gene COMPARTMENTS Subcellular localization image for CPED1 gene
Compartment Confidence
endoplasmic reticulum 5
golgi apparatus 2
extracellular 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CPED1 Gene

Pathways & Interactions for CPED1 Gene

SuperPathways for CPED1 Gene

No Data Available

Interacting Proteins for CPED1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000309772 for CPED1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CPED1 Gene


No data available for Pathways by source and SIGNOR curated interactions for CPED1 Gene

Drugs & Compounds for CPED1 Gene

No Compound Related Data Available

Transcripts for CPED1 Gene

Unigene Clusters for CPED1 Gene

Cadherin-like and PC-esterase domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CPED1 Gene

No ASD Table

Relevant External Links for CPED1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CPED1 Gene

mRNA expression in normal human tissues for CPED1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CPED1 Gene

This gene is overexpressed in Artery - Tibial (x7.9), Artery - Coronary (x4.5), and Artery - Aorta (x4.1).

Protein differential expression in normal tissues from HIPED for CPED1 Gene

This gene is overexpressed in Monocytes (48.5) and Ovary (20.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CPED1 Gene

SOURCE GeneReport for Unigene cluster for CPED1 Gene Hs.189652

genes like me logo Genes that share expression patterns with CPED1: view

Protein tissue co-expression partners for CPED1 Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for CPED1 Gene

Orthologs for CPED1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CPED1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CPED1 35
  • 86.88 (n)
  • 81.84 (a)
CPED1 36
  • 81 (a)
(Canis familiaris)
Mammalia CPED1 35
  • 84.78 (n)
  • 80.36 (a)
CPED1 36
  • 76 (a)
(Mus musculus)
Mammalia Cped1 35
  • 80.64 (n)
  • 74.93 (a)
Cped1 16
Cped1 36
  • 75 (a)
(Pan troglodytes)
Mammalia CPED1 35
  • 99.25 (n)
  • 98.83 (a)
CPED1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Cped1 35
  • 80.67 (n)
  • 74.24 (a)
(Monodelphis domestica)
Mammalia CPED1 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia CPED1 36
  • 63 (a)
(Gallus gallus)
Aves CPED1 35
  • 66.6 (n)
  • 57.93 (a)
CPED1 36
  • 55 (a)
(Anolis carolinensis)
Reptilia CPED1 36
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cped1 35
  • 59.7 (n)
  • 52.14 (a)
(Danio rerio)
Actinopterygii cped1 35
  • 51.59 (n)
  • 42.44 (a)
cped1 36
  • 37 (a)
Species with no ortholog for CPED1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CPED1 Gene

Gene Tree for CPED1 (if available)
Gene Tree for CPED1 (if available)

Paralogs for CPED1 Gene

(2) SIMAP similar genes for CPED1 Gene using alignment to 6 proteins: Pseudogenes for CPED1 Gene

genes like me logo Genes that share paralogs with CPED1: view

No data available for Paralogs for CPED1 Gene

Variants for CPED1 Gene

Sequence variations from dbSNP and Humsavar for CPED1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs17143165 - 121,124,389(+) TGACA(C/T)TATGA reference, missense
rs41281692 - 121,136,043(+) AGCTG(C/G)AGTTC reference, missense
VAR_038666 -
rs798911 - 121,271,408(+) GGGGA(A/C)GTGTG reference, missense
rs767737 -- 121,038,327(+) ATTAA(A/G)AAGGG intron-variant

Variation tolerance for CPED1 Gene

Residual Variation Intolerance Score: 66.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.78; 73.58% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CPED1 Gene

Disorders for CPED1 Gene

Relevant External Links for CPED1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CPED1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CPED1 Gene

Publications for CPED1 Gene

  1. Novel eukaryotic enzymes modifying cell-surface biopolymers. (PMID: 20056006) Anantharaman V. … Aravind L. (Biol. Direct 2010) 2 3 67
  2. Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. (PMID: 24945404) Kemp J.P. … Evans D.M. (PLoS Genet. 2014) 3
  3. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. (PMID: 22504420) Estrada K. … Rivadeneira F. (Nat. Genet. 2012) 3
  4. Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. (PMID: 22792070) Medina-Gomez C. … Rivadeneira F. (PLoS Genet. 2012) 3
  5. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3

Products for CPED1 Gene

Sources for CPED1 Gene